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Teriparatide as a Regenerative Therapy in Knee Osteoarthritis

Research Question:
Does the medication Teriparatide help with osteoarthritis of the knee?

Basic Study Information

Purpose:
If you decide to take part in this study, you will be asked to complete UP TO 16 study visits over the course of the next two and a half years. This study will determine if the drug Teriparatide (Forteo)improves arthritis in knee joints. If you have osteoarthritis in your knee you may be eligible to enroll. You will be assigned by chance (like flipping a coin) to one of two groups. Group 1 will receive the study drug (teriparatide) and Group 2 will receive a placebo (saline). There is an equal chance that you will be assigned to either group. Study Staff members will not know which group you have been assigned to. You will be asked to inject yourself with the study injection pen every day for 24 weeks. A nurse will teach you how to administer the injection. As a part of these visits study staff will ask you to rate your pain and test your physical function. They will also collect height, weight, blood pressure, pulse, collect blood and urine samples and pain surveys. You will have x rays and MRIs of your knee.

Location: URMC Orthopaedics, Clinton Crossings Building D
Study Reference #: NA6

Lead Researcher (Principal Investigator)

Lead Researcher: Christopher Ritchlin

Study Contact Information

Study Coordinator: Samantha Hoffman
Phone: (585) 341-9056
Email: Ortho_Research@urmc.rochester.edu

Additional Study Details

Study Details:
Eligible participants will be compensated for their time.

Number of Visits:  More than 10
Parking:  Free
Reimbursement:  Yes

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