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Welcome to the Multiphoton Imaging Core Facility

About the Multiphoton SRL

The mission of the URMC Multiphoton Shared Resource Laboratory (SRL) is to provide state-of-the-art multiphoton imaging capabilities to further the biomedical and bio-optical research at the URMC and the University of Rochester with emphasis on intravital imaging and systems physiology.

The Multiphoton SRL provides access to a state-of-the-art Olympus Fluoview FVMPE-RS multiphoton imaging system for deep tissue high-spatial and high-temporal resolution imaging. The two-photon system combines high speed, deep observation capability with multi-color imaging, which will meet a myriad of experiment needs. Further capabilities of the core facility include engineering applications for opto-electronics and spectroscopy, and software development for quantitative image analysis, visualization and instrument control.

Information for New/Perspective Users

Training and access to the imaging system are available as well as supported in the design of experimental procedures, acquisition of image data, and analysis of the required images. Our services are available to all investigators within the University as well as academic or commercial/industrial institutions in the region. If you are interested in using the multiphoton system, please contact the technical director for a consultation.

The use of laboratory animals covered by active UCAR-protocols, tissue explants, and cell-cultures, and radio-active tracer substances is permitted. We also offer access to a chemical hood, and isoflurane vaporizers. Please ensure compliance with all intramural and extramural regulations regarding use of research animals and hazardous materials before accessing the Multiphoton SRL. Contributions made by the core facility should be mentioned in the acknowledgments of scientific publications. If the work performed in the core facility is more than routine, publication as co-author is appropriate.