This Center has established a multidisciplinary, collaborative, integrated, and iterative program focused on the conduct of research activities to understand the etiology and impact of viral respiratory pathogens and to develop and evaluate strategies for their control, treatment, and prevention. Specifically, we provide a team of experienced investigators and technical staff with expertise in clinical research and laboratory methods, experience working with respiratory pathogens and the diseases they cause, immunological responses and assays, animal models, vaccinology, and clinical genomics, proteomics, and bioinformatics. This Center is comprised of faculty and staff from the University of Rochester, the University of Alabama, J. Craig Venter Institute, and Oregon Health and Sciences University. The individual projects focus on infant immune responses and disease after RSV infection, the impact of commensal and opportunistic infections on infant immune system development and lung function, studies on experimental and licensed influenza vaccines; pilot projects on non-TB mycobacterial infection and disease, and influenza adaptation, and supports a Bacterial Respiratory Pathogen Reference Laboratory.
The mission of the NIAID Respiratory Pathogens Research Center (RPRC) is to provide NIAID resources to conduct clinical and translational research activities to understand the etiology and impact of viral and bacterial respiratory pathogens, and to develop and evaluate strategies for their control, treatment, and prevention.
RPRC Innovation Research Program
The primary objective of the RPRC Innovation Research Program is to facilitate highly innovative research activities that take advantage of novel technologies and new research opportunities, or that respond to emergent issues in viral respiratory pathogens, focusing on high priority translational and/or clinical research. A major set of goals for the program is to:
Encourage new collaborations with investigators outside of the RPRC
Infuse the RPRC with novel technologies and approaches
Attract new faculty to the Center and to viral respiratory pathogens research
Assist junior faculty to develop productive research programs
Expand our funding in the area of translational research
Seed the development of independently (extramural) funded research application