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April 2018

Part III: The Power and Promise of RNA

Part III: The Power and Promise of RNA

RNA presents an entirely new pool of drugs targets and provides an opening to correct diseases that don’t respond to conventional drugs. Lynne Maquat is working to gain a deeper understanding of RNA and the sophisticated mechanisms related to nonsense-mediated mRNA decay.

Part I: Lynne Maquat’s 40-Year-Voyage to Solve the Mysteries of Gene Expression

Part I: Lynne Maquat’s 40-Year-Voyage to Solve the Mysteries of Gene Expression

Years of meticulous focus led to Lynne Maquat’s discovery of nonsense-mediated mRNA decay (NMD), one of the most prominent surveillance systems in the body to protect against mistakes in gene expression that lead to disease. Poised on one of the newest and most promising frontiers of discovery, her work in the burgeoning field of RNA biology may one day help to cure nearly every disease on the planet.