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Cell & Developmental Biology

Kate Ackerman, Ph.D. Kate G. Ackerman, M.D., M.B.A.

  | Associate Professor, Pediatrics

Research Interest:
Congenital Diaphragmatic Hernia.

 

Brian J. Altman, Ph.D.Brian J. Altman, Ph.D.

  | Visit Lab Website

Assistant Professor, Biomedical Genetics

Research Interest:
Role of Circadian Rhythm in in gene regulation and cancer cell biology and metabolism. 

 

Douglas M. Anderson, Ph.D.Douglas M. Anderson, Ph.D.

  | Visit Lab Website

Assistant Professor - Department of Pharmacology and Physiology (SMD)

Research Interest:
LncRNA control of heart development and disease; Discovery and function of micropeptides encoded by putative lncRNAs; Genome-editing by RNA-guided nucleases.

 

Jeevisha Bajaj, Ph.D.Jeevisha Bajaj, Ph.D.

  | Assistant Professor | Lab Website

Research Interest:
Role of cancer stem cell interactions with their microenvironment in disease progression.

 

Daniel T. Bergstralh, Ph.D.Daniel T. Bergstralh, Ph.D.

  | Assistant Professor | Visit Lab Website

Research Interest:
Investigating cell division and adhesion in epithelial tissues, with a particular interest in how tissue integrity is established and maintained during development.

 

Bradford C. Berk, M.D., Ph.D.Bradford C. Berk, M.D., Ph.D.

  | Visit Lab Website

Professor - Department of Medicine , Cardiology (SMD)

Professor - Department of Neurology (SMD)

Professor - Department of Pharmacology and Physiology (SMD)

Distinguished University Professor - President's Office (UR)

Research Interest:
Signaling transduction mechanisms in the vascular system.

 

Dirk Bohmann, Ph.D.Dirk Bohmann, Ph.D.

  | Professor, Biomedical Genetics

Research Interest:
Genetics of transcription factors and their role in aging and disease.

 

Stephen Dewhurst, Ph.D.Stephen Dewhurst, Ph.D.

  | Visit Lab Website

Professor - Department of Microbiology and Immunology (SMD)

Albert and Phyllis Ritterson Professorship - Department of Microbiology and Immunology (SMD)

Associate Vice President for Health Sciences Research - Office of Sr VP for Research (UR)

Vice Dean for Research, SMD - Dean's Office M&D - Administration (SMD)

Research Interests:
Understanding the interaction of HIV with glial cells; Developing an improved live attenuated influenza vaccine (LAIV); Elucidating the host cell response to infection by viral pathogens (with emphasis on SARS-CoV-2 and Adeno-associated virus, AAV).

 

Dmitri N. Ermolenko, Ph.D.Dmitri N. Ermolenko, Ph.D.

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Associate Professor - Department of Biochemistry and Biophysics (SMD)

Research Interest:
Structural dynamics of the ribosome and ribosomal ligands during proteins synthesis, regulation of protein synthesis by mRNA structure in normal and diseased cells, and mechanisms of antibiotic action.

 

Isaac S. Harris, Ph.D.Isaac S. Harris, Ph.D.

  | Visit Lab Website

Assistant Professor, Department of Biomedical GeneticsDepartment of Pharmacology and Physiology 

Research Interest:
The role of antioxidants in disease and the development of novel strategies to manipulate them therapeutically.

 

Amy Kiernan, Ph.D.Amy Kiernan, Ph.D.

  | Lab Website  

Assistant Professor, Biomedical Genetics 

Research Interests:
Molecular development of the eye and inner ear; anterior segment dysgenesis (ASD) and developmental glaucoma; congenital deafness and vestibular dysfunction.

 

Xin Zhiguo Li, Ph.D.Xin Zhiguo Li, Ph.D.

 Visit Lab Website

Investigation of the germ cell genome, the only genome carrying the duty of integrating new information with genetic history, enabling reproduction and evolution—the key difference between life and non-life.

 

Richard Libby, Ph.D.Richard Libby, Ph.D.

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Research Interest:
Neurobiology of glaucoma, molecular processes that lead to retinal ganglion cell death.

 

Alayna E. Loiselle, Ph.D.Alayna E. Loiselle, Ph.D.

  | Lab Website

Associate Professor, Department of Orthopaedics , Department of Biomedical Engineering, Department of Pathology and Laboratory Medicine | 

Research Interest:
Musculoskeletal tissue regeneration.

 

Sanjay B. Maggirwar, M.B.A., Ph.D.Sanjay B. Maggirwar, M.B.A., Ph.D.

  |

 

 

 

Lynne Elizabeth Maquat, Ph.D.Lynne Elizabeth Maquat, Ph.D.

  | Visit Lab Website

Associate Professor, Biochemistry & Biophysics 

Research Interest:
The molecular basis of human diseases, including but not limited to the most common single-gene cause of intellectual disability and autism, Fragile X Syndrome, and the development of therapeutics. 

 

Thomas J. Mariani, Ph.D.Thomas J. Mariani, Ph.D.

  | Visit Lab Website

Professor - Department of Pediatrics , Neonatology (SMD)

David H. Smith Professor in Pediatrics - Department of Pediatrics (SMD)

Professor (Part-Time) - Department of Environmental Medicine (SMD)

Professor - Department of Biomedical Genetics (SMD)

Research Interest:
Genetic mechanisms of susceptibility to congenital and infectious lung diseases, focusing on developmental antecedents and the influence of environmental factors. 

 

Margot Mayer-Pröschel, Ph.D.Margot Mayer-Pröschel, Ph.D.

  | Lab website

Professor, Biomedical GeneticsNeuroscience

Research Interest:
Identification of different stem and precursor cell pools in CNS that may be critical for cell replacement therapies or are targets of insults that lead to developmental pathologies.

 

Helene McMurray, Ph.D.Helene McMurray, Ph.D.

  | Visit Lab Website

Assistant Professor, Biomedical Genetics

Research Interests:
tRNA biogenesis, function and quality control; intellectual disability due to deficiencies.

 

Martha Susiarjo, Ph.D.Martha Susiarjo, Ph.D.

Email MarthaSusiarjo

Susiarjo Lab

Environmental Medicine

Research Interest:
Our research program focuses on mechanisms underlying gene environment interaction in pregnancy. We are interested in elucidating how environmental factors influence epigenetic regulation of developmental-relevant genes including imprinted genes, and how exposure modulates maternal-fetal health.

Karl Glastad, Ph.D. Karl Glastad, Ph.D. 

 | Lab Website

Assistant Professor

Research Interest: Plasticity of aging, stress response, and metabolism. Also behavioral plasticity, why not?

 

Joseph M. Miano, Ph.D. Joseph M. Miano, Ph.D.

  | Adjunct Professor - Department of Medicine , Aab Cardiovascular Research Institute (SMD)

 

 

Keith Nehrke, Ph.D.Keith Nehrke, Ph.D.

  | Visit Lab website

Professor, Department of Medicine , Department of Pharmacology and Physiology 

Research Interest:
Integrative Physiology.

 

Mark Noble, Ph.D.Mark Noble, Ph.D.

  | Professor, Biomedical Genetics

Research Interests:
Discovering new treatments for afflictions that lack satisfactory therapies, and to better understand the toxicity of currently used medicines; studies span normal and pathological cell function, with focus on stem and progenitor cells.

 

Michael O'Reilly, Ph.D.Michael O'Reilly, Ph.D.

  | Professor, Pediatrics

Research Interest:
Effects of newborn hypoxia on lung and heart development.

 

Catherine E. Ovitt, Ph.D.Catherine E. Ovitt, Ph.D.

 | Visit Lab Website

Professor - Department of Biomedical Genetics (SMD)

Interim Director, Oral & Craniofacial Biology - Department of Dentistry (SMD)

Research Interest:
Protective and regenerative strategies for salivary gland function and radiation therapies.

 

Alexander R. Paciorkowski, M.D.Alexander R. Paciorkowski, M.D.

  | Associate Professor - Department of Biomedical Genetics

Research Interests:
tRNA biogenesis, function and quality control; intellectual disability due to deficiencies in tRNA modifications.

 

Eric M. Phizicky, Ph.D.Eric M. Phizicky, Ph.D.

  Visit Lab Website

Professor - Department of Biochemistry and Biophysics (SMD)

Research Interest:
tRNA biogenesis, function and quality control; intellectual disability due to deficiencies in tRNA modifications.

 

Peng Yao, Ph.D.Peng Yao, Ph.D.

  | Lab website

Associate Professor, Department of Medicine , Department of Biochemistry and Biophysics

Research Interest:
Pathophysiological function and molecular mechanism of new non-coding RNAs (and RBPs) and new modes of gene regulation in cardiac system and cardiovascular disease.

 

Christoph Pröschel, Ph.D.Christoph Pröschel, Ph.D.

  | Associate Professor, Biomedical Genetics

Research Interest:
Defining roles of glial progenitor cells and astrocytes as critical modulators in responses to chemical exposure, injury, or stress; discovering how exogenous factors contribute to neurodegenerative diseases; and developing new approaches to treat traumatic injury and neurodegenerative diseases.

 

Jacques Robert, Ph.D.Jacques Robert, Ph.D.

  | Visit Lab Website

Professor - Department of Microbiology and Immunology, Interim Chair Department of Microbiology and Immunology, Professor - Department of Environmental Medicine Vice Chair - Department of Microbiology and Immunology |

Research Interest:
Experimental platform using the amphibian Xenopus for research in immunotoxicology, fundamental and medical immunology.
 

Jacques Robert, Ph.D. Marlies P. Rossmann, M.D., Ph.D. 

Research Interest: Elucidate the metabolic origins of a variety of diseases, facilitate novel metabolism-centered differentiation therapies for hematological malignancies, and combat the decline in lymphoid cell production by the aging hematopoietic system.

 

Jacques Robert, Ph.D.Regina K. Rowe, M.D., Ph.D.

 | Visit Rowe Lab

Research Interest:
Mechanisms of how allergic inflammation impacts innate immune cell antiviral responses.

 

Andrew Samuelson, Ph.D.Andrew Samuelson, Ph.D.

  | Assistant Professor, Biomedical Genetics

Research Interest:
Aging at the Genetic, Molecular and Organismal Level.

 

Edward M. Schwarz, Ph.D.Edward M. Schwarz, Ph.D.

  | Visit Lab Website

Professor - Department of Orthopaedics , Center for Musculoskeletal Research

Director - Center for Musculoskeletal Research

Richard and Margaret Burton Distinguished Professor in Orthopaedics - Department of Orthopaedics

Professor - Department of Urology

Professor - Department of Medicine , Allergy/Immunology and Rheumatology

Professor - Department of Pathology and Laboratory Medicine

Professor - Department of Microbiology and Immunology

Professor - Department of Biomedical Engineering

Research Interest:
Inflammatory bone loss as seen in rheumatoid arthritis, infections, tumor metastasis and wear debris induced osteolysis around prosthetic implants.

 

Ruchira Singh, Ph.D.Ruchira Singh, Ph.D.

  | Assistant Professor, Ophthalmology

Research Interest:
Cellular and molecular mechanisms of retinal and neurodegenerative diseases in patient-derived induced pluripotent stem cell (iPSC) model systems.

 

Eric Small, Ph.D.Eric Small, Ph.D.

  | Associate Professor, MedicinePharmacology & PhysiologyBiomedical Engineering

Research Interest:
Cellular and molecular mechanisms of heart development, disease, and regeneration; Transcriptional regulation of fibroblast plasticity and cardiac fibrosis.

 

Harold C. Smith, Ph.D.Harold C. Smith, Ph.D.

| Professor (Part-Time) - Department of Biochemistry and Biophysics (SMD)

 


 

Laurie A. Steiner, M.D.Laurie A. Steiner, M.D.

 | Visit Steiner Lab

Associate Professor - Department of Pediatrics, Neonatology (SMD)

Research Interest:
Understanding how regulation of RNA Polymerase II activity regulates cellular differentiation, with a focus on erythropoiesis. Delineating epigenetic control of normal erythropoiesis; determining the contribution of disrupted epigenetic regulation to inherited anemias.

 

Michel Telias, Ph.D.Michel Telias, Ph.D.

  | Visit Lab website

Assistant Professor, Department of OphthalmologyDepartment of Neuroscience, Center for Visual Science A&S (RC) 

Research Interest:
Signaling mechanisms linking neuronal activity and gene expression.

 

Juilee Thakar, Ph.D.Juilee Thakar, Ph.D.

  | Visit Lab Website

Associate Professor - Department of Microbiology and Immunology (SMD)

Associate Professor - Department of Biostatistics and Computational Biology (SMD) - Joint

Associate Professor - Department of Biomedical Genetics (SMD) - Joint

Research Interest:
Signaling mechanisms linking neuronal activity and gene expression.

 

Charles A. Thornton, M.D.Charles A. Thornton, M.D.

  | Visit Lab website

Professor, Department of NeurologySaunders Family Distinguished Professor in Neuromuscular Research - Department of Neurology (SMD)Department of Neuroscience

Research Interests:
Neurogenetics, experimental therapeutics, repeat expansion diseases.

 

Ning Wang, PhDNing Wang, PhD

Email NingWang

|  Ning-Wang Lab

Assistant Professor

Research Interest: Cell biology, biochemistry, and molecular genetics; Organelle biogenesis; Organelle degradation through selective autophagy; Organelle aging and neurodegeneration; Cellular stress response

 

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