URMC / New York Influenza Center of Excellence / Publications / 2018 Publications 2018 Publications 2020 | 2019 | 2018 | 2017 | 2016 | Archived 2018, December Nogales A, Martinez-Sobrido L, Topham DJ, DeDiego ML Modulation of Innate Immune Responses by the Influenza A NS1 and PA-X Proteins. PMID: 30545063 2018, October Brown DM, Hixon AM, Oldfield LM, Zhang Y, Novotny M, Wang W, Das SR, Shabman RS, Tyler KL, Scheuermann RH. Contemporary Circulating Enterovirus D68 Strains Have Acquired the Capacity for Viral Entry and Replication in Human Neuronal Cells. PMID: 30327438 Ávila-Pérez G, Nogales A, Martín V, Almazán F, Martínez-Sobrido L Reverse Genetic Approaches for the Generation of Recombinant Zika Virus. PMID: 30384426 Rodriguez L, Nogales A, Iqbal M, Perez DR, Martinez-Sobrido L Identification of Amino Acid Residues Responsible for Inhibition of Host Gene Expression by Influenza A H9N2 NS1 Targeting of CPSF30. PMID: 30405591 Martínez-Sobrido L, Peersen O, Nogales A Temperature Sensitive Mutations in Influenza A Viral Ribonucleoprotein Complex Responsible for the Attenuation of the Live Attenuated Influenza Vaccine. PMID: 30326610 Márquez-Jurado S, Nogales A, Ávila-Pérez G, Iborra FJ, Martínez-Sobrido L, Almazán F An Alanine-to-Valine Substitution in the Residue 175 of Zika Virus NS2A Protein Affects Viral RNA Synthesis and Attenuates the Virus In Vivo. PMID: 30301244 2018, September Nogales A, Martinez-Sobrido L, Chiem K, Topham DJ, DeDiego ML Functional Evolution of the 2009 Pandemic H1N1 Influenza Virus NS1 and PA in Humans. PMID: 30021892 DeDiego ML, Chiem K, Topham DJ Directed selection of amino acid changes in the influenza hemagglutinin and neuraminidase affecting protein antigenicity. PMID: 30224200 Davis AKF, McCormick K, Gumina ME, Petrie JG, Martin ET, Xue KS, Bloom JD, Monto AS, Bushman FD, Hensley SE Sera from Individuals with Narrowly Focused Influenza Virus Antibodies Rapidly Select Viral Escape Mutations In Ovo. PMID: 30045982 2018, August Topham DJ, Nguyen P, Sangster MY Pandemic influenza vaccines: what they have taught us about B cell immunology. PMID: 29957457 Richards KA, Treanor JJ, Nayak JL, Sant AJ Overarching Immunodominance Patterns and Substantial Diversity in Specificity and Functionality in the Circulating Human Influenza A and B Virus-Specific CD4+ T-Cell Repertoire. PMID: 29762692 Pardi N, Parkhouse K, Kirkpatrick E, McMahon M, Zost SJ, Mui BL, Tam YK, Karikó K, Barbosa CJ, Madden TD, Hope MJ, Krammer F, Hensley SE, Weissman D Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies. PMID: 30135514 Guthmiller JJ, Wilson PC Harnessing immune history to combat influenza viruses. PMID: 29890370 DiPiazza AT, Richards KA, Liu WC, Albrecht RA, Sant AJ Analyses of Cellular Immune Responses in Ferrets Following Influenza Virus Infection. PMID: 30151589 2018, July Sant AJ, DiPiazza AT, Nayak JL, Rattan A, Richards KA CD4 T cells in protection from influenza virus: Viral antigen specificity and functional potential. PMID: 29944766 Albrecht RA, Liu WC, Sant AJ, Tompkins SM, Pekosz A, Meliopoulos V, Cherry S, Thomas PG, Schultz-Cherry S Moving Forward: Recent Developments for the Ferret Biomedical Research Model. PMID: 30018107 Cobey S, Gouma S, Parkhouse K, Chambers BS, Ertl HC, Schmader KE, Halpin RA, Lin X, Stockwell TB, Das SR, Landon E, Tesic V, Youngster I, Pinsky BA, Wentworth DE, Hensley SE, Grad YH Poor Immunogenicity, Not Vaccine Strain Egg Adaptation, May Explain the Low H3N2 Influenza Vaccine Effectiveness in 2012-2013. PMID: 29471464 Zhang H, Henry C, Anderson CS, Nogales A, DeDiego ML, Bucukovski J, Martinez-Sobrido L, Wilson PC, Topham DJ, Miller BL Crowd on a Chip: Label-Free Human Monoclonal Antibody Arrays for Serotyping Influenza. PMID: 29985597 Brouillette RB, Phillips EK, Patel R, Mahauad-Fernandez W, Moller-Tank S, Rogers KJ, Dillard JA, Cooney AL, Martinez-Sobrido L, Okeoma C, Maury W TIM-1 Mediates Dystroglycan-Independent Entry of Lassa Virus. PMID: 29875238 2018, June Garretson TA, Petrie JG, Martin ET, Monto AS, Hensley SE Identification of human vaccinees that possess antibodies targeting the egg-adapted hemagglutinin receptor binding site of an H1N1 influenza vaccine strain. PMID: 29861178 2018, May Lewnard JA, Cobey S Immune History and Influenza Vaccine Effectiveness. PMID: 29883414 Babu TM, Perera R, Wu JT, Fitzgerald T, Nolan C, Cowling BJ, Krauss S, Treanor JT, Peiris M Population Serologic Immunity to human and avian H2N2 viruses in the United States and HongKong for Pandemic Risk Assessment. PMID: 29762672 2018, April Krammer F, Fouchier RAM, Eichelberger MC, Webby RJ, Shaw-Saliba K, Wan H, Wilson PC, Compans RW, Skountzou I, Monto AS NAction! How Can Neuraminidase-Based Immunity Contribute to Better Influenza Virus Vaccines? PMID: 29615508 Richards KA, DiPiazza AT, Rattan A, Knowlden ZAG, Yang H, Sant AJ Diverse Epitope Specificity, Immunodominance Hierarchy, and Functional Avidity of Effector CD4T Cells Established During Priming Is Maintained in Lung After Influenza A Virus Infection. PMID: 29681900 DiPiazza A, Laniewski N, Rattan A, Topham DJ, Miller J, Sant AJ CD4 T cell epitope specificity and cytokine potential are preserved as cells transition from the lung vasculature to lung tissue following influenza infection. PMID: 29669836 Sant AJ, Richards KA, Nayak J Distinct and complementary roles of CD4 T cells in protective immunity to influenza virus. PMID: 29621639 Chen YQ, Wohlbold TJ, Zheng NY, Huang M, Huang Y, Neu KE, Lee J, Wan H, Rojas KT, Kirkpatrick E, Henry C, Palm AE, Stamper CT, Lan LY, Topham DJ, Treanor J, Wrammert J, Ahmed R, Eichelberger MC, Georgiou G, Krammer F, Wilson PC Influenza Infection in Humans Induces Broadly Cross-Reactive and Protective Neuraminidase-Reactive Antibodies. PMID: 29625056 Wang J, Hilchey SP, DeDiego M, Perry S, Hyrien O, Nogales A, Garigen J, Amanat F, Huertas N, Krammer F, Martinez-Sobrido L, Topham DJ, Treanor JJ, Sangster MY, Zand M Broad cross-reactive IgG responses elicited by adjuvanted vaccination with recombinant influenza hemagglutinin (rHA) in ferrets and mice. PMID: 29641537 2018, March Nogales A, Piepenbrink MS, Wang J, Ortega S, Basu M, Fucile CF, Treanor JJ, Rosenberg AF, Zand MS, Keefer MC, Martinez-Sobrido L, Kobie JJ A Highly Potent and Broadly Neutralizing H1 Influenza-Specific Human Monoclonal Antibody. PMID: 29531320 Rodriguez L, Reedy S, Nogales A, Murcia PR, Chambers TM, Martinez-Sobrido L Development of a novel equine influenza virus live-attenuated vaccine. PMID: 29331866 2018, February Anderson CS, McCall PR, Stern HA, Yang H, Topham DJ Antigenic cartography of H1N1 influenza viruses using sequence-based antigenic distance calculation. PMID: 29433425 Chauché C, Nogales A, Zhu H, Goldfarb D, Ahmad Shanizza AI, Gu Q, Parrish CR, Martínez-Sobrido L, Marshall JF, Murcia PR Mammalian Adaptation of an Avian Influenza A Virus Involves Stepwise Changes in NS1. PMID: 29237841 Duffney PF, McCarthy CE, Nogales A, Thatcher TH, Martinez-Sobrido L, Phipps RP, Sime PJ Cigarette smoke dampens antiviral signaling in small airway epithelial cells by disrupting TLR3 cleavage. PMID: 29351447 2018, January Henry C, Palm AE, Krammer F, Wilson PC From Original Antigenic Sin to the Universal Influenza Virus Vaccine. PMID: 28867526