Welcome to the Department of Biochemistry & Biophysics
I made the leap from natural-product chemistry at Hobart College to the atomic-level world of protein and RNA structure in the Wedekind lab at the University of Rochester, where we primarily use X-ray crystallography to visualize biological molecules. more ...
The Department of Biochemistry & Biophysics (B&B) strives to understand the molecular mechanisms of important biological processes, thereby providing insight into how disruption of these mechanisms causes disease. Departmental research is generously supported by the National Institutes of Health (NIH). NIH instrument funds have contributed to our recent two million dollar investment in cutting edge structural biology, biophysical and mass spectrometry-based equipment. Furthermore, income generated from intellectual property derived from departmental research discoveries continues to be reinvested back into the department, and used to stimulate the genesis of private biotechnology companies.
In addition to supporting our research, the NIH has recognized our excellence in the Biochemistry & Molecular Biology (BMB) and Biophysics, Structural & Computational Biology (BSCB) Ph.D. programs by awarding the university a highly competitive interdepartmental T32 graduate training grant. Our commitment to graduate education is apparent from the positions acquired by our previous students and fellows, who are professors at major research universities and leaders in corporate research. Our continued focus on pioneering research and quality education ensures our position as a premier Biochemistry & Biophysics department.
Genomic analysis of genes, expression and codon usage more info...
- Coarse-grained molecular dynamics provides insight into the interactions of lipids and cholesterol with rhodopsin. Adv Exp Med Biol. 796, 75-94. (2014 Jan 01).
- Fluorescent approaches for understanding interactions of ligands with G protein coupled receptors. Biochim Biophys Acta. 1838, 15-33. (2014 Jan 01).
- Dynamics of adhesion molecule domains on neutrophil membranes: surfing the dynamic cell topography. Eur Biophys J. 42, 851-5. (2013 Dec 01).