Hongmei Yang, PhDHongmei.Yang

Research Assistant Professor
Ph.D. (2007) North Carolina State University


Contact Information:

University of Rochester
Dept of Biostatistics and Computational Biology
265 Crittenden Boulevard, CU 420630 
Rochester, New York 14642-0630
Office: Saunders Research Building 4148
Phone: (585) 275-0411
Fax: (585) 273-1031
E-mail: Hongmei_Yang@urmc.rochester.edu

Research Interests

My research is practically driven, a combination of active collaborations in HIV, Influenza, and other diseases and independent research. In summary it falls in three areas: statistical processing of assay data (e.g., Elispot, Elisa, and Hemagglutination assays), mixed-effect models for correlated data, and variable selection for high dimensional data.

Selected Publications

  • Nayak, J.L., Fitzgerald, T.F., Richards, K.A., Yang, H., Treanor, J.J. and Sant, A.J. (2012). CD4 T-cell Expansion Predicts Neutralizing Antibody Responses to Monovalent Inactivated Pandemic H1N1 Influenza Vaccine. Journal of Infectious Diseases Accepted.
  • Yang, H., Topham, D.J., Holden-Wiltse, J. andWu, H. (2012). Statistical Estimation & Inference of Cell Counts from ELISPOT Limiting Dilution Assays. Journal of Biopharmaceutical Statistics. Accepted.
  • Henn, A.D., Laski, M., Yang, H., Qiu, X., Miao, H., Barry, C.T.,Welle, S.,Wu, H. and Zand, M.S. (2012) Functionally Distinct Subpopulations of CpG-Activated Memory B Cells. Nature Scientific Reports. doi:10.1038/srep00345.
  • Sundararajan, A., Huan, L., Richards, K.A., Marcelin, G., Alam, S., Joo, H., Yang, H., Webby, R.J., Topham, D.J., Sant, A.J. and Sangster, M.Y. (2012) Host Differences in Influenza-Specific CD4 T Cell and B Cell Responses are Modulated by Viral Strain and
    Route of Immunization. PLoS One. 2012;7(3):e34377.
  • Lartey M, Sagoe KW, Yang H, Kenu E, Xexemeku F, Oliver-Commey J, Boima V, Seshie M, Sagoe A, Mingle JAA, Flanigan TP, Wu H, Kwara A (2011). Viral Decay Rates are Similar in HIV-infected Patients with and without TB Coinfection during Treatment with an Efavirenz-based Regimen. Clinical Infectious Diseases 52(4): 547-550.

  • Quách TD, Manjarrez-Orduño N, Adlowitz DG, Silver L, Yang H, Wei C, Milner EC, Sanz I (2011). Anergic responses characterize a large fraction of human autoreactive naive B cells expressing low levels of surface IgM. Journal of Immunology 186(8):4640-8. Epub 2011 Mar 11.
  • Barnett S, Klein JD, Pollard Jr RQ, Samar V, Schlehofer D, Starr M, Sutter E, Yang H, Pearson TA (2011). Community participatory research with deaf sign language users to identify health inequities. American Journal of Public Health 101(12):2235-8. Epub 2011 Oct 20.
  • Baer J, Santiago F, Yang H, Wu H, Holden-Wiltse J, Treanor J, Topham DJ (2010). B Cell Responses to H5 Influenza HA in Human Subjects Vaccinated with Drifted Variants. Vaccine 28(4): 907-915.
  • Kyu SY, Kobie J, Yang H, Zand MS, Topham DJ, Quataert SA, Sanz I, Lee FE (2009). Frequencies of human influenza-specific antibody secreting cells or plasmablasts post vaccination from fresh and frozen peripheral blood mononuclear cells. Journal of Immunological Methods 340(1):42-7.