Research Labs

Our faculty, staff and students work as a team to create an atmosphere of learning, growing and life-long friendships. If you are interested in joining our team, please feel free to contact us for more information.

Charles J. Lowenstein , M.D.

Dr. Charles LowensteinDr. Lowenstein's research is focused on vascular biology. One team of researchers explores mechanisms of exocytosis, through which endothelial cells release pro-inflammatory and pro-thrombotic mediators. A second group of scientists study how platelets communicate with endothelial cells. A third area of research involves an exploration of the role of microRNA in endothelial cells. A fourth team investigates how nitric oxide affects vascular inflammation. View Lowenstein Lab page

Bradford C. Berk, M.D., Ph.D.

Berk Lab small photoDr. Berk's laboratory is focused on defining the mechanisms by which cells in the vascular wall respond to hemodynamic and hormonal stimuli. View Berk Lab page

Mark B. Taubman, M.D.

Mark TaubmanDr. Taubman's laboratory is focused on the role of vascular smooth muscle cells (SMC) in regulating inflammation and thrombosis in the arterial wall. There are three major areas of investigation.
View Taubman Lab page

Jun-ichi Abe, M.D., Ph.D.

Jun-ichi AbeIn the last four years, I have been interested in the mechanism of atherosclerosis and myocardial infarction, especially in the role of oxidative stress, hypoxia, and hyperglycemia.

View Abe Lab page

Zheng-Gen Jin, Ph.D.

Zheng-Gen JinDr. Jin’s research has been focused on molecular regulation of vascular endothelial function. Vascular endothelial cells in blood vessels produce a number of vasodilator and vasoconstrictor substances that not only physiologically regulate vasomotor tone and vascular homeostasis, but also mediate the recruitment and activity of inflammatory cells and the propensity towards atherosclerotic lesion
formation and thrombosis in the pathological condition. View Jin Lab page

Slava Korshunov , Ph.D.

Slava KorshunovDr. Korshunov's major focus is the understanding of mechanisms that regulate the structure of blood vessels (a process we call “vascular remodeling”) could prevent cardiovascular morbidity and mortality in humans.
View Korshunov Lab page

 

Coeli Lopes, Ph.D.

Coeli LopesThe major focus of Dr. Lopes current work involves the regulation of the slow delayed rectifier-like current (IKs) in the heart and the pathogenesis of the Long QT (LQT1) syndrome. View Lopes Lab page

Joseph Miano, Ph.D.

Miano LabMy lab utilizes state-of-the-art methods in molecular biology, genetics, genomics, and computational biology to acquire in-depth knowledge on the transcriptional regulation of gene expression and the functional role of regulatory proteins in Alzheimer’s disease and vascular occlusive disease.

View Miano Lab page

Craig Morrell, DVM, Ph.D.

Morrell LabPlatelets have two major functions: hemostastis/thrombosis and an immune regulatory function. My laboratory uses in vitro techniques and in vivo mouse models to study both important platelet functions.
View Morrell Lab page

Eric Small, Ph.D.

Eric SmallResearch in the Small Lab is focused on understanding the molecular mechanisms that control how a cell responds to its surroundings during development or following tissue injury.
View Small Lab page

Jane Sottile, Ph.D.

Jane SottileRemodelling of extracellular matrices occurs during development, wound healing, and in a variety of pathological processes including atherosclerosis, ischemic injury, and angiogenesis. Perturbing matrix remodelling events by preventing the turnover of extracellular matrix molecules, or by increasing the levels of matrix degrading proteases or inhibitors has been shown to result in fibrosis, arthritis, reduced angiogenesis, and developmental abnormalities.

View Sottile Lab page

R. James White, M.D., Ph.D.

Jim WhiteThe overall goal of my laboratory is to understand the pathobiology which causes vascular remodeling in severe human pulmonary hypertension. Severe pulmonary hypertension (PH) occurs in idiopathic form and is also observed in diseases as diverse as chronic venous thromboembolism, scleroderma, HIV infection, and cirrhosis.

View White Lab page

Chen Yan, Ph.D.

Chen YanRegulation and function of cyclic nucleotide phosphodiesterases in the cardiovascular system. Second messenger cyclic nucleotides (cAMP and cGMP) regulate many signaling pathways in the cardiovascular system.

View Yan Lab page

watch our commercials