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Oral Health Research

The Eastman Institute for Oral Health, ranking in the top five for NIDCR dentistry funding, continues to gain international attention for breakthrough discoveries.

We work on a wide range of projects, including oral infectious diseases, salivary gland biology, craniofacial development, and community-based disease prevention. We focus on basic-science research as well as translational, clinical and community dentistry research.

We have four specific research goals as we expand our capabilities:

1. To boost our national reputation as a research institution
2. To enhance clinical and translational research
3. To better integrate basic with translational and clinical research efforts
4. To improve the overall quality and number of research-intensive faculty

Our Latest Publications

• Access to oral health services for urban low-income Latino children: social ecological influences. J Public Health Dent. 2011 Aug 19. Telleen S, Rhee Kim YO, Chavez N, Barrett RE, Hall W, Gajendra S.
• Endosseous arteries in the anterior mandible: literature review.Int J Oral Maxillofac Implants. 2012 Jan;27(1):90-4. Romanos GE, Gupta B, Crespi R.
• An alternative multiple pontic design for a fixed implant-supported prosthesis. J Prosthet Dent. 2011 Sep;106(3):198-203. Del Castillo R, Ercoli C, Delgado JC, Alcaraz J.
• Pro-apoptotic gene knockdown mediated by nanocomplexed siRNA reduces radiation damage in primary salivary gland cultures. J Cell Biochem. 2012 Jan 17
  Arany S, Xu Q, Hernady E, Benoit DS, Dewhurst S, Ovitt CE.
• Role of calcium and PKC in salivary mucous cell exocrine secretion. J Dent Res. 2011 Dec;90(12):1469-76. Culp DJ, Zhang Z, Evans RL.
• Role of glucosyltransferase B in interactions of Candida albicans with Streptococcus mutans and with an experimental pellicle on hydroxyapatite surfaces. Appl Environ Microbiol. 2011 Sep;77(18):6357-67. Gregoire S, Xiao J, Silva BB, Gonzalez I, Agidi PS, Klein MI, Ambatipudi KS, Rosalen PL, Bauserman R, Waugh RE, Koo H.
• A novel technique for tailored surface modification of dental implants - a step wise approach based on plasma immersion ion implantation. Clin Oral Implants Res. 2011 Dec 15. Meirelles L, Uzumaki ET, Lima JH, Muller CA, Albrektsson T, Wennerberg A, Lambert CS.
• Expression of Ecto-ATPase NTPDase2 in Human Dental Pulp. J Dent Res. 2011 Dec 14. Liu X, Yu L, Wang Q, Pelletier J, Fausther M, Sévigny J, Malmström HS, Dirksen RT, Ren YF.
• The Influence of Verification Jig on Framework Fit for Nonsegmented Fixed Implant-Supported Complete Denture.Clin Implant Dent Relat Res. 2011 Dec 16.
  Ercoli C, Geminiani A, Feng C, Lee H.
• Mutation of NADH oxidase (nox) reveals an overlap of the oxygen- and acid-meditated stress responses in Streptococcus mutans. Appl Environ Microbiol. 2011 Dec 16. Derr AM, Faustoferri RC, Betzenhauser MJ, Gonzalez K, Marquis RE, Quivey RG Jr.
• Comparison of Modified Widman and Coronally Advanced Flap Surgery Combined with Co2 Laser Root Irradiation in Periodontal Therapy: A 15-Year Follow-up. Crespi R, Cappare P, Gherlone E, Romanos GE. Int J Periodontics Restorative Dent. 2011 Nov;31(6):641-51.
• Microcomputed Tomographic Analysis of Bone Reaction at Insertion of Orthodontic Mini-implants in Sheep.Int J Oral Maxillofac Implants. 2011 Nov;26(6):1233-40. Rebaudi A, Laffi N, Benedicenti S, Angiero F, Romanos GE.
  
• Osteoarthritis accelerates and exacerbates Alzheimer's disease pathology in mice. Kyrkanides S, Tallents RH, Miller JN, et al. J Neuroinflammation. 2011 Sep 7;8:112.
  
• Ren, Y. (2011). Dental erosion: Etiology, diagnosis and prevention. RDH, 31(8), 75-84.
• Implementing a Smoke-free Campus: a Medical Center initiative. J Community Health. 2011 Aug;36(4):684-92. Gajendra S, Ossip DJ, Panzer RJ, McIntosh S.
• The antimicrobial effect of Iseganan HCl oral solution in patients receiving stomatotoxic chemotherapy: analysis from a multicenter, double-blind, placebo-controlled, randomized, phase III clinical trial.J Oral Pathol Med. 2011 Nov 14. Elad S, Epstein JB, Raber-Durlacher J, Donnelly P, Strahilevitz J.
• Severe Defects in Absorptive Ion Transport in Distal Colons of Mice that Lack ClC-2 Channels.Gastroenterology. 2011 Nov 9. Catalán MA, Flores CA, González-Begne M, Zhang Y, Sepúlveda FV, Melvin JE.
• Miconazole Induces Fungistasis and Increases Killing of Candida albicans Subjected to Photodynamic Therapy(†).Photochem Photobiol. 2011 Nov 12. Snell SB, Foster TH, Haidaris CG.
• Role of Dentifrices With Essential Oil Formulations in Periodontal Healing. Am J Med Sci. 2011 Nov 2. Javed F, Al-Hezaimi K, Romanos GE.
  
• Prenatal exposure to dental amalgam: Evidence from the Seychelles Child Development Study main cohort. J Am Dent Assoc. 2011 Nov;142(11):1283-94. Watson GE, Lynch M, Myers GJ, Shamlaye CF, Thurston SW, Zareba G, Clarkson TW, Davidson PW.
• Maxillary sinus augmentation with a sonic handpiece for the osteotomy of the lateral window: A clinical report. J Prosthet Dent. 2011 Nov;106(5):279-83. Geminiani A, Papadimitriou DE, Ercoli C.
• Clinical Evaluation of Immediate Loading of Electroeroded Screw-Retained Titanium Fixed Prostheses Supported by Tilted Implant: A Multicenter Retrospective Study.  Clin Implant Dent Relat Res. 2011 Oct 20. Acocella A, Ercoli C, Geminiani A, Feng C, Billi M, Acocella G, Giannini D, Sacco R.
• Simplified orthodontic tooth movement with dental implants and orthodontic elastics: a clinical report. J Prosthet Dent. 2011 Jun;105(6):363-6. Rotella M, Geminiani A, Ercoli C.
• Nonfluoride caries-preventive agents: executive summary of evidence-based clinical recommendations. J Am Dent Assoc. 2011 Sep;142(9):1065-1071. Billings RJ, et al.
• Transcriptome analysis reveals that ClpXP proteolysis controls key virulence properties of Streptococcus mutans. Microbiology. 2011 Oct;157(Pt 10):2880-90. Kajfasz JK, Abranches J, Lemos JA.
• Characterization of the human submandibular/sublingual saliva glycoproteome using lectin affinity chromatography coupled to Multidimensional Protein Identification Technology.J Proteome Res. 2011 Sep 21. Gonzalez-Begne M, Lu B, Liao L, Xu T, Bedi G, Melvin JE, Yates JR.
• A comparison of stress distributions for different surgical procedures, screw dimensions and orientations for a Temporomandibular joint implant. J Biomech. 2011 Sep 23;44(14):2584-7. Chowdhury AR, Kashi A, Saha S.
• An alternative multiple pontic design for a fixed implant-supported prosthesis. J Prosthet Dent. 2011 Sep;106(3):198-203. Del Castillo R, Ercoli C, Delgado JC, Alcaraz J.
• Osteoarthritis accelerates and exacerbates Alzheimer's disease pathology in mice. J Neuroinflammation. 2011 Sep 7;8(1):112. Kyrkanides S, Tallents RH, Miller JN, Olschowka ME, Johnson R, Yang M, Olschowka JA, Brouxhon SM, O'Banion MK.