Quantitative Myometry

Background: There a number of clinical methods for quantifying muscle strength. The classical method using the five point MRC scale is useful in clinical care settings and when averaged over a large number of muscle groups to give a measure of global clinical severity. However, the MRC is an ordinal scale is and is not suited for quantitative measurement of strength in a single muscle group. Quantitative myometry is currently being used in the Fields Center as a measure of disease severity of the muscle that is being sampled by needle biopsy. The methods described have been previously used to study the natural history of FSHD (FSH dystrophy) and in subsequent clinical trials

Maximum Isometric Voluntary Contraction Testing (MVICT): (Download PDF file)



For more information, please contact the Fields Center FieldsCenter@urmc.rochester.edu