PI: Dr. Soo Lee

Soo OK Lee

Dr. Soo Ok Lee

Research Assistant Professor of Pathology

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Email: Soook_Lee@urmc.rochester.edu

 

Dr. Soo Ok Lee's Publications (PDF files are available when you click individual publication)

  1. Lee, S O. The influence of polypeptides on the terminal galactosylation of murine immunoglobulin G. A Ph.D. thesis of Graduate program in Biochemistry, Rutgers university and the university of Medicine and Dentistry of New Jersey, New Brunswick, New Jersey. (1989)

  2. Lee, S-O., Connolly, J.M., Ramirez-Soto, D. and Poretz, R.D. The polypeptide of Immunoglobulin G influences its galactosylation in vitro. J.Biol. Chem. 265, 5833-5839 (1990)

  3. Lee, S-O. and Poretz, R.D. Hybrid myeloma cells which secrete heterodimeric IgG: A model to study the N-linked glycan. Immunology and Cell Biology 69, 151-157 (1991)

  4. Lee, S.O. and Na D.S. Eukaryotic Gene Expression and its Control (Review) The 3th Symposium in Dermatology, (1993)

  5. Kim, S.B., Kim, W.S., Lee, S.O., Lee, K.P., Park, J.S. and Na, D.S. Lipocortin inhibits proliferation of cultured human mesangial cells. Nephron 74, 39-44 (1996)

  6. Huh, K.R., Cho, E.H., Lee, S.O. and Na, D.S. High level expression of human lipocortin (annexin) 1 in Escherichia coli. Biotechnology Letters 18, 163-168 (1996)

  7. Kim, H.W., Choi, E.A., Yoo, B., Lee, K.P., Lee, S.O., Moon, H-B. and Na, D.S. Lipocortin 1 binding sites on human T lymphocytes: population with LC-1 binding sites is larger in CD8+ T cells than in CD4+ T cells. Biochem. Intl. 40, 1167-1173 (1996)

  8. Kim, G-Y., Lee, H-B., Lee, S.O., Rhee, H.J. and Na, D.S. Chaperone like function of lipocortin-1 in human glomerulonephritis. Nephrology 2, 235-240 (1996)

  9. Park, H., Jang. Y.J., Kim, D.H., Lee, S.O. and Doe Sun Na. Transient increase of lipocortin 1 nuclei of the hippocampal pyramidal neurons in rats by immobilization stress. J. Biochem. Mol. Biol. 31, 117-122, (1998)

  10. Lee, H.J., Kim, S.W., Lee, S.O., Park, Y.M. and Na, D.S. Translocation of Annexin 1 to the nucleus by Epidermal Growth Factor in A549 cells. J. Biochem. Mol. Biol. 32, 28-32 (1999)

  11. Ni, Z., Lou, W., Dhir, R., de Miguel, F., Lee, S.O., Grandis, J.R., and Gao, A.C. Selective activation of members of the STATs family in prostate carcinomas. J. of Urology 167, 1859-1862 (2002)

  12. de Miguel, F., Lou, W., Lee, S.O., Xiao, X., Pflug, B., Nelson, J.B., and Gao, A.C. Stat3 enhances the growth of LNCaP human prostate cancer cells in intact and castrated male nude mice. Prostate 52, 123-9 (2002)

  13. Lee, S.O. Lou, W, Hou, M., Onate, S.A., and Gao, A.C. Interleukin-4 enhances prostate specific antigen expression by activation of the androgen receptor and Akt pathway. Oncogene 22, 6047-6044, (2003)

  14. Lee, S.O., Lou, W., de Miguel, F., Hou, M. and Gao, A.C. Interleukin-6 promotes androgen-independent growth in LNCaP human prostate cancer cells. Clin. Can. Res. 9, 370-376 (2003)

  15. de Miguel, F., Lee, S.O., Onate, S.A. and Gao, A.C. Sta3 enhances transactivation of steroid hormone receptors. Nuc. Receptor 1, 3-7 (2003)

  16. Lee, S.O., Lou, W., Hou, M, Johnson, C.S., Trump, D.L. and Gao A.C. Interleukin-6 protects LNCaP cells from apoptosis induced by androgen deprivation through the Stat3 pathway. Prostate 60, 178-186, (2004)

  17. Lee, S.O., Lou, W., Qureshi, K.M., Mehraein-Ghomi, F., and Gao A.C. RNA interference targeting Stat3 inhibits growth and induces apoptosis of human prostate cancer cells. Prostate 60, 303-309, (2004)

  18. Dong, Y, Lee, S.O., Zhang, H., Marshall, J., Gao, A.C. and Ip C. Prostate specific antigen expression is down-regulated by selenium through disruption of androgen receptor signaling Cancer Res. 64, 19-22, (2004)

  19. Lee, S.O. and Gao, A.C. STAT3 and transactivation of steroid hormone receptors. Vitam. Horm. 70, 33-57 (2005) (review)

  20. Lee, S.O., Lou, W., Lin, X. and Gao, A.C. Requirement for NFkB in interleukin-4-induced androgen receptor activation in prostate cancer cells. Prostate 64,160-167, (2005)

  21. Tan, D.F., Hou, M., Lee, S.O., Lou, W, Wang, J., Trump, D.L. and Gao, A.C. Interleukin-6 polymorphism and risk of advanced prostate cancer. J. Urology 174, 753-756, (2005)

  22. Lee, S.O., Chun, J.Y., Nadiminty, N. and Gao, A.C. Monomethylated selenium inhibits growth of LNCaP human prostate cancer xenograft accompanied by a decrease in the expression of androgen receptor and prostate-specific antigen (PSA). Prostate 66, 1070-1075 (2006)

  23. Nadiminty, N., Chun, J.Y., Lee, S.O., Onate, S.A., Lou, W., and Gao A.C. Mechanism of selenium down regulation of androgen receptor signaling in prostate cancer. Mol.Cancer Thera. 5, 913-918 (2006)

  24. Nadiminty, N., Lou, W., Lee, S.O., Lin, X., Trump, D.L. and Gao, A.C. Stat3 activation of NFkB p100 processing involves CBP/p300 mediated acetylation. Proc. Natl. Acad. Sci. U.S.A. 103, 7264-7269 (2006)

  25. Nadiminty, N., Lou, W., Lee, S.O., Mehraein-Ghomi, F., Kirk, J.S., Conroy, J.F., Zhang, H and Gao, A.C. Prostate specific antigen (PSA) modulates genes involved in bone remodeling and induces osteoblast differentiation of human osteosarcoma cell line SaOS-2. Clin. Can. Res. 12, 1420-1430 (2006)

  26. Lee, S.O., Nadiminty, N., Wu, X.X., Lou, W., Dong, Y, IP, C, Onate, S.A. and Gao, A.C. Selenium disrupts estrogen signaling by altering estrogen receptor expression and ligand binding in human breast cancer cells. Cancer Res. 65, 3487-92 (2005)

  27. Lee, S.O., Chun, J.Y., Nadiminty, N., Lou, W. and Gao, A.C. Interleukin-6 undergoes transition from growth inhibitor associated with neuroendocrine differentiation to stimulator accompanied by androgen receptor activation during LNCaP prostate cancer cell progression. Prostate 67, 764-773 (2007)

  28. Lee S.O., Dutt, S.S., Nadiminty, N., Pinder, E., Liao, H and Gao A.C. Development of an androgen- deprivation induced and androgen suppressed human prostate cancer cell line. Prostate 67, 1293-1300 (2007)

  29. Lee S.O., Chun J.Y., Hu Y., Pinder, E., Lou W., and Gao A.C. Interleukin-4 stimulates androgen- independent growth in LNCaP human prostate cancer cells. Prostate 68, 85-91 (2008)

  30. Lee S.O., Chun, J.Y., Nadiminty, N., Lou, W., Feng, S., Gao, A.C. Interleukin-4 activates androgen receptor through CBP/p300. Prostate 69 126-132 (2009)

 

Contact

Soo Ok Lee
University of Rochester
Box 626
601 Elmwood Ave.
Rochester, NY 14642
+1-585-273-4501
Soook_Lee@URMC.rochester.edu

Other PIs' Emails

 
Chawnshang Chang, Ph.D.

 

Chawnshang Chang, Ph.D.
Shu-Yuan Yeh, Ph.D.

 

Shu-Yuan Yeh, Ph.D.
Yi-Fen Lee, Ph.D.

 

Yi-Fen Lee, Ph.D.
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Hiroshi Miyamoto , MD. Ph.D.
HueiJu Ting

 

HueiJu Ting, Ph.D.
JeffLin's Photo Wen-Jye Lin, Ph.D