Honors & News
January 12, 2015
Andrew Shubin Awarded Grant from National Cancer Institute
Andrew Shubin, a graduate student in Danielle Benoit's lab, was awarded an F30 grant from the National Cancer Institute (NCI) for his project titled
Poly(ethylene glycol) Hydrogels for Salivary Gland Regeneration.
Radiation for head and neck cancers causes severe damage to salivary glands resulting in permanent dry mouth. This issue greatly affects the quality of life for cancer survivors, as proper saliva production is essential for eating, speaking, and oral hygiene. This project aims to develop at 3D tissue engineering scaffold utilizing poly(ethylene glycol) hydrogels in order to regenerate salivary gland tissue to help treat this condition.
- Disruption of cell-cell contact-mediated notch signaling via hydrogel encapsulation reduces mesenchymal stem cell chondrogenic potential. J Biomed Mater Res A. In press. (2014 Dec 11).
- Development and in vitro assessment of enzymatically-responsive poly(ethylene glycol) hydrogels for the delivery of therapeutic peptides. Biomaterials. 35, 9719-30. (2014 Dec 01).
- Degradable hydrogels for spatiotemporal control of mesenchymal stem cells localized at decellularized bone allografts. Acta Biomater. 10, 3431-41. (2014 Aug 01).