Principal Investigator
Working in the Lab
Post-Doctoral Fellows
Study of the Tumor Extracellular Matrix Using Second Harmonic Generation
Posted on: Wednesday, December 8, 2010.
Multiple opportunities exist for scientists with backgrounds in second harmonic generation (SHG) imaging, tumor biology, multiphoton laser-scanning microscopy, and/or biomedical imaging.
The focus of the research will be to study the tumor extracellular matrix using SHG imaging. We will initially focus on several improvements to a technique we have recently developed (Han et al., Optics Express (2010) 18(8): pp.10538-10550) for measurement of the ratio of forwards-propagating SHG to backwards-propagating SHG. We will also apply this technique to the study of tumor samples.
Specific Qualifications
The successful candidate will have a Ph.D. or M.D., an interest in cancer, SHG, and/or biomedical imaging, as well as a demonstrated level of productivity. Optics, immunohistochemistry, laboratory pathology, and/or animal surgery experience are also desirable. Positions are available for highly qualified Postdoctoral Fellows funded by a 5-year DoD Breast Cancer Research Program Era of Hope Scholar Research Award, as well as a 5-year NIH Director's New Innovator Award.
Interested applicants should send an application package (in a single PDF file) via email with the subject line 'Postdoctoral Applicant') to Dr. Brown. The application package should contain:
- CV including a letter describing their interests
- A list of publications and references
Recent Publications
- (2012 Feb 01). Two-photon and second harmonic microscopy in clinical and translational cancer research. Ann Biomed Eng. 40, 277-91.
- (2011 Dec 01). Measuring intranodal pressure and lymph viscosity to elucidate mechanisms of arthritic flare and therapeutic outcomes. Ann N Y Acad Sci. 1240, 47-52.
- (2011 Dec 01). β-Adrenergic receptors (β-AR) regulate VEGF and IL-6 production by divergent pathways in high β-AR-expressing breast cancer cell lines. Breast Cancer Res Treat. 130, 747-58.
