Honors & News
October 3, 2014
Professor Diane Dalecki and Professor Denise Hocking Receive NIH Grant
Diane Dalecki, Ph.D. (BME) and Denise C. Hocking, Ph.D. (Pharmacology & Physiology) have received a $2 million grant from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) for their project titled
Ultrasound standing wave fields for vascular engineering. The goal of this 4-year project is to advance a novel ultrasound technology to fabricate complex, functional microvascular networks within three-dimensional engineered constructs.
Collaborators on this project are Maria Helguera, Ph.D. (Imaging Sciences, RIT), Ingrid Sarelius, Ph.D. (Pharmacology & Physiology) and Angela Glading, Ph.D. (Pharmacology & Physiology).
New, versatile vascularization strategies are needed to produce small-scale 3D tissue models and are critical for the fabrication of large-scale engineered tissues. The noninvasive capacity of ultrasound also enables innovative capabilities for fabricating microvessel networks within hydrogels injected within tissues. The successful completion of this project will provide new tools for tissue engineering and for a variety of clinical reconstructive and vascular surgery applications.
- Estimating cell concentration in three-dimensional engineered tissues using high frequency quantitative ultrasound. Ann Biomed Eng. 42, 1292-304. (2014 Jun 01).
- Characterizing collagen microstructure using high frequency ultrasound. J Acoust Soc Am. 135, 2373. (2014 Apr 01).
- Investigation of effects of ultrasound on dermal wound healing in diabetic mice. J Acoust Soc Am. 135, 2370. (2014 Apr 01).