Principal Investigator

Diane Dalecki, Ph.D. University of Rochester work Box 270168 Rochester NY 14627-0168 office: Goergen Hall 310 p 585-275-7378 f 585-276-1999 dalecki@bme.rochester.edu

Honors & News

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December 10, 2010

Hocking & Dalecki Research Image Featured on Cover of Tissue Engineering

Immunofluorescence image captured by two-photon microscopy showing cell nuclei (blue), fibronectin (green), and actively proliferating cells (red) in a three-dimensional tissue body. Featured on the cover of Tissue Engineering (2010).

An immunofluorescence image captured by two-photon microscopy by Carlos Sevilla, has been featured as the cover for the December issue of Tissue Engineering. The image is featured in an article by BME graduate student Carlos Sevilla, co-authored by Dr. Dalecki and Dr. Denise Hocking.

The article entitled, Extracellular Matrix Fibronectin Stimulates the Self-Assembly of Microtissues on Native Collagen Gels, demonstrates a novel role for cell-mediated fibronectin fibrillogenesis in the formation and vertical assembly of microtissues, and provide a novel approach for engineering complex tissue architecture.
July 26, 2010

BME Students Participate in the David T. Kearns Symposium

Six current BME students participated in the summer session of the David T. Kearns Research Symposium for Leadership and Diversity in the Arts, Sciences, and Engineering by presenting posters about their research. The symposium was held on Thursday July 29, 2010 in the Sloan Auditorium at Goergen Hall, and was sponsored by the David T. Kearns Center for Leadership and Diversity in Arts, Sciences, and Engineering.

Threshold of Non-Eye Movement Vestibular Cells in Alert Monkeys

Daniel Barbash, mentored by Laurel Carney

Analysis of SHG (Second Harmonic Generation) Microscopy Sensitivity to Experimental Parameters

Jacy Bulaon, mentored by Edward Brown III

Investigating Acoustic Parameters that Optimize Ultrasound Standing Wave Fields for Cell Banding

Jasmine Carvalho, mentored by Diane Dalecki

Strategies for Erythrocyte Maturation In Vitro

Eric Lam, mentored by Richard Waugh

Identifying Potential Transcription Factors Regulating Cellulose Degradation in Ethanol Production in Clostridium Thermocellum

Kathleen Maloney, mentored by J.H. David Wu

Novel Parthenolide Delivery System for Leukemia Treatment

Hannah Watkins, mentored by Danielle Benoit
July 1, 2010

Sally Child Celebrates 45^th Anniversary at the University of Rochester

This month the RCBU recognizes Sally Child's 45 years of employment at the University of Rochester! Sally began employment at the University of Rochester in June 1965 in the Department of Electrical Engineering. She was first hired by Professor Edwin Carstensen as a technician for his laboratory that was dedicated to studying the biological effects of ultrasound and electric fields. Sally worked with Professor Carstensen for over 30 years, and in that time established herself as a key member in the broader community of scientists involved in advancing the use of ultrasound in medicine and biology. Upon the retirement of Professor Carstensen, Sally began to work with Professor Diane Dalecki and moved to the Department of Biomedical Engineering in 2000. Again, her efforts focused on researching the use of ultrasound in diagnostic imaging and developing new therapeutic applications of ultrasound.

Currently, Sally is a Senior Technical Associate, an author of approximately 70 publications, and a recognized expert in biomedical ultrasound. Sally has been a member of the Rochester Center for Biomedical Ultrasound since its founding. Throughout her career, Sally has provided expert training and guidance to numerous graduate and undergraduate students. Sally has made significant contributions to our understanding of the interaction of ultrasound with biological tissues and systems. Her ingenuity and technical skill are invaluable to progress in our lab, said Professor Diane Dalecki, Director of the Rochester Center for Biomedical Ultrasound. The field of biomedical ultrasound and the University of Rochester community are indebted to her dedicated efforts and contributions throughout her 45 years of service.
May 5, 2010

BME Graduate Diana Ladkany Awarded Tau Beta Pi Graduate Fellowship

Diana K. Ladkany, BME class of 2009, has received a graduate fellowship from Tau Beta Pi for the 2010-11 year. Tau Beta Pi, the world's largest engineering society, awarded Ladkany a cash stipend of $10,000 to pursue her medical education at the University of Rochester School of Medicine and Dentistry. An honors student, Ladkany is the president of the New York Kappa Chapter of Tau Beta Pi, a member of the Rochester Early Medical Scholars, a member of Phi Beta Kappa Academic Honor Society, and a Girl Scout Gold Award Recipient. Tau Beta Pi membership represents the highest honor that can be obtained by an engineering student and is awarded on the basis of high scholarship and exemplary character. Tau Beta Pi Fellowships are awarded on the basis of high scholarship, campus leadership and service, and the promise of future contributions to the engineering profession.Through her junior and senior years, Diana has been involved in research on the effects of biomedical ultrasound on cellular processes as a member of Professor Diane Dalecki's laboratory.
April 28, 2010

Kelley Garvin Wins Best Student Paper Competition

Kelley Garvin won the Best Student Paper Competition at the 159^th Meeting of the Acoustical Society of America held in Baltimore, MD from April 19-23. Her invited paper, titled Ultrasound standing wave fields induce endothelial cell sprouting within three-dimensional engineered tissues was recognized as the Best Student Paper in the Biomedical Ultrasound/Bioresponse to Vibration Technical Section. This was the second year in a row that Kelley has won this award. Kelley presented her recent work demonstrating the use of ultrasound standing wave fields to spatially organize cells and induce endothelial cell sprouting in three-dimensional engineered tissues.

Kelley is a graduate student in the Department of Biomedical Engineering (BME) and her thesis research is co-advised by Dr. Diane Dalecki and Dr. Denise Hocking. Kelley is also a student member of the Rochester Center for Biomedical Ultrasound (RCBU) and organizer of the Ultrasound Journal Club. Kelley's research is part of a larger, multidisciplinary project, led by Drs. Dalecki and Hocking and funded by the NIH that aims to develop novel ultrasound technologies for the field of tissue engineering.
April 26, 2010

BME Undergraduate Nicholas Berry Wins Research Award

Nicholas Berry (UR BME class of 2010) was awarded the Professors' Choice Award for Undergraduate Research in Engineering at the UR Undergraduate Research Expo held on April 23, 2010. Nick was awarded this honor for his scientific poster titled, High Frequency Pulse-Echo Ultrasound for Three- Dimensional Engineered Tissue Characterization. In his research, Nick has developed a high-frequency ultrasound system to be used to characterize the biological, structural, and mechanical properties of three-dimensional engineered tissues. Nick has been working on this project for a summer and two semesters. His coauthors on this work are Diane Dalecki, Maria Helguera, and Denise Hocking.
April 13, 2010

Dr. Diane Dalecki honored as Professor of the Year in Engineering

During the Undergraduate Research Exposition, on April 23^rd, an awards ceremony will be held, in part, honoring Dr. Diane Dalecki as Professor of the Year in Engineering. This award is presented by the University of Rochester Students' Association for excellence in undergraduate teaching.
March 22, 2010

BME Undergraduate Jasmine Carvalho Awarded a Xerox Undergraduate Fellowship

BME undergraduate student Jasmine Carvalho has been awarded a Xerox Undergraduate Research Fellowship. Jasmine will be working in the laboratory of Diane Dalecki, RCBU Director and Associate Professor of Biomedical Engineering, on a project related to the use of ultrasound in cell and tissue engineering. The UR SEAS Xerox Undergraduate Fellows Program is a highly competitive program that provides engineering students with research experience. The program begins during the summer preceding the senior year, and continues as an independent research course in the fall and spring semesters of the senior year.