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Principal Investigator

Tim R. Mosmann, Ph.D. University of Rochester work Rochester NY p 585-275-9120 Tim_Mosmann@urmc.rochester.edu

Recent Publications

The following list was auto-generated 1 week ago.

• 1. Weaver JM
  2. Yang H
  3. Roumanes D
  4. Lee FE
  5. Wu H
  6. Treanor JJ
  7. Mosmann TR
  (2013 Jan 01). Increase in IFNγ(-)IL-2(+) cells in recent human CD4 T cell responses to 2009 pandemic H1N1 influenza. PLoS One. 8, e57275.
• 1. Li X
  2. Miao H
  3. Henn A
  4. Topham DJ
  5. Wu H
  6. Zand MS
  7. Mosmann TR
  (2012 Jun 29). Ki-67 expression reveals strong, transient influenza specific CD4 T cell responses after adult vaccination. Vaccine. 30, 4581-4.
• 1. Qi Y
  2. Operario DJ
  3. Georas SN
  4. Mosmann TR
  (2012 Jan 01). The acute environment, rather than T cell subset pre-commitment, regulates expression of the human T cell cytokine amphiregulin. PLoS One. 7, e39072.
• 1. Qi Y
  2. Operario DJ
  3. Oberholzer CM
  4. Kobie JJ
  5. Looney RJ
  6. Georas SN
  7. Mosmann TR
  (2010 Dec 01). Human basophils express amphiregulin in response to T cell-derived IL-3. J Allergy Clin Immunol. 126, 1260-6.e4.
• 1. Mosmann TR
  2. Kobie JJ
  3. Lee FE
  4. Quataert SA
  (2009 Dec 01). T helper cytokine patterns: defined subsets, random expression, and external modulation. Immunol Res. 45, 173-84.
• 1. Seavey MM
  2. Mosmann TR
  (2009 Apr 14). Estradiol-induced vaginal mucus inhibits antigen penetration and CD8(+) T cell priming in response to intravaginal immunization. Vaccine. 27, 2342-9.
• 1. Zaiss DM
  2. Sijts AJ
  3. Mosmann TR
  (2008 Oct 01). Enumeration of cytotoxic CD8 T cells ex vivo during the response to Listeria monocytogenes infection. Infect Immun. 76, 4609-14.
• 1. Rebhahn JA
  2. Bishop C
  3. Divekar AA
  4. Jiminez-Garcia K
  5. Kobie JJ
  6. Lee FE
  7. Maupin GM
  8. Snyder-Cappione JE
  9. Zaiss DM
  10. Mosmann TR
  (2008 Oct 01). Automated analysis of two- and three-color fluorescent Elispot (Fluorospot) assays for cytokine secretion. Comput Methods Programs Biomed. 92, 54-65.
• 1. Seavey MM
  2. Mosmann TR
  (2008 Jan 01). Immunoregulation of fetal and anti-paternal immune responses. Immunol Res. 40, 97-113.
• 1. Lee FE
  2. Walsh EE
  3. Falsey AR
  4. Lumb ME
  5. Okam NV
  6. Liu N
  7. Divekar AA
  8. Hall CB
  9. Mosmann TR
  (2007 Jun 15). Human infant respiratory syncytial virus (RSV)-specific type 1 and 2 cytokine responses ex vivo during primary RSV infection. J Infect Dis. 195, 1779-88.
• 1. Zaiss DM
  2. Yang L
  3. Shah PR
  4. Kobie JJ
  5. Urban JF
  6. Mosmann TR
  (2006 Dec 15). Amphiregulin, a TH2 cytokine enhancing resistance to nematodes. Science. 314, 1746.
• 1. Seavey MM
  2. Mosmann TR
  (2006 Dec 01). Paternal antigen-bearing cells transferred during insemination do not stimulate anti-paternal CD8+ T cells: role of estradiol in locally inhibiting CD8+ T cell responses. J Immunol. 177, 7567-78.
• 1. Kobie JJ
  2. Shah PR
  3. Yang L
  4. Rebhahn JA
  5. Fowell DJ
  6. Mosmann TR
  (2006 Nov 15). T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5'-adenosine monophosphate to adenosine. J Immunol. 177, 6780-6.
• 1. Snyder-Cappione JE
  2. Divekar AA
  3. Maupin GM
  4. Jin X
  5. Demeter LM
  6. Mosmann TR
  (2006 Feb 15). HIV-specific cytotoxic cell frequencies measured directly ex vivo by the Lysispot assay can be higher or lower than the frequencies of IFN-gamma-secreting cells: anti-HIV cytotoxicity is not generally impaired relative to other chronic virus responses. J Immunol. 176, 2662-8.
• 1. Divekar AA
  2. Zaiss DM
  3. Lee FE
  4. Liu D
  5. Topham DJ
  6. Sijts AJ
  7. Mosmann TR
  (2006 Feb 01). Protein vaccines induce uncommitted IL-2-secreting human and mouse CD4 T cells, whereas infections induce more IFN-gamma-secreting cells. J Immunol. 176, 1465-73.
• 1. Yang L
  2. Kobie JJ
  3. Mosmann TR
  (2005 Nov 15). CD73 and Ly-6A/E distinguish in vivo primed but uncommitted mouse CD4 T cells from type 1 or type 2 effector cells. J Immunol. 175, 6458-64.
• 1. Lee FE
  2. Walsh EE
  3. Falsey AR
  4. Liu N
  5. Liu D
  6. Divekar A
  7. Snyder-Cappione JE
  8. Mosmann TR
  (2005 Nov 01). The balance between influenza- and RSV-specific CD4 T cells secreting IL-10 or IFNgamma in young and healthy-elderly subjects. Mech Ageing Dev. 126, 1223-9.
• 1. Yang L
  2. Mosmann T
  (2004 Jun 01). Synthesis of several chemokines but few cytokines by primed uncommitted precursor CD4 T cells suggests that these cells recruit other immune cells without exerting direct effector functions. Eur J Immunol. 34, 1617-26.
• 1. Snyder JE
  2. Bowers WJ
  3. Livingstone AM
  4. Lee FE
  5. Federoff HJ
  6. Mosmann TR
  (2003 Feb 01). Measuring the frequency of mouse and human cytotoxic T cells by the Lysispot assay: independent regulation of cytokine secretion and short-term killing. Nat Med. 9, 231-5.
• 1. Wang X
  2. Mosmann T
  (2001 Oct 15). In vivo priming of CD4 T cells that produce interleukin (IL)-2 but not IL-4 or interferon (IFN)-gamma, and can subsequently differentiate into IL-4- or IFN-gamma-secreting cells. J Exp Med. 194, 1069-80.
• 1. Mosmann T
  (2000 Apr 01). Reply to cohen Immunol Today. 21, 199.