Principal Investigators

M. Kerry O'Banion, M.D., Ph.D. University of Rochester work Box 603 601 Elmwood Ave Rochester NY 14642 office: MC 5-8527A p 585-275-5185 Kerry_obanion@urmc.rochester.edu

John A. Olschowka, Ph.D. University of Rochester work Box 603 601 Elmwood Ave Rochester NY 14642 office: MC 5-6312 p 585-275-8238 john_olschowka@urmc.rochester.edu

Recent Publications

The following list was auto-generated 1 day ago.

1. Latchney SE
2. Hein AM
3. O'Banion MK
4. Dicicco-Bloom E
5. Opanashuk LA
(2013 May 01). Deletion or activation of the aryl hydrocarbon receptor alters adult hippocampal neurogenesis and contextual fear memory. J Neurochem. 125, 430-45.
1. Brouxhon SM
2. Kyrkanides S
3. Teng X
4. Raja V
5. O'Banion MK
6. Clark R
7. Byers SW
8. Silberfeld A
9. Tornos C
10. Ma L
(2013 Apr 25). Monoclonal antibody against the ectodomain of E-cadherin (DECMA-1) suppresses breast carcinogenesis: Involvement of the HER/PI3K/Akt/mTOR and IAP pathways. Clin Cancer Res. In press.
1. Montgomery SL
2. Narrow WC
3. Mastrangelo MA
4. Olschowka JA
5. O'Banion MK
6. Bowers WJ
(2013 Apr 05). Chronic Neuron- and Age-Selective Down-Regulation of TNF Receptor Expression in Triple-Transgenic Alzheimer's Disease Mice Leads to Significant Modulation of Amyloid- and Tau-Related Pathologies. Am J Pathol. In press.
1. Wu MD
2. Montgomery SL
3. Rivera-Escalera F
4. Olschowka JA
5. O'Banion MK
(2013 Mar 16). Sustained IL-1β expression impairs adult hippocampal neurogenesis independent of IL-1 signaling in nestin(+) neural precursor cells. Brain Behav Immun. In press.
1. Ghosh S
2. Wu MD
3. Shaftel SS
4. Kyrkanides S
5. LaFerla FM
6. Olschowka JA
7. O'Banion MK
(2013 Mar 13). Sustained interleukin-1β overexpression exacerbates tau pathology despite reduced amyloid burden in an Alzheimer's mouse model. J Neurosci. 33, 5053-64.
1. Brouxhon SM
2. Kyrkanides S
3. Teng X
4. Athar M
5. Ghazizadeh S
6. Simon M
7. O'Banion MK
8. Ma L
(2013 Jan 14). Soluble E-cadherin: a critical oncogene modulating receptor tyrosine kinases, MAPK and PI3K/Akt/mTOR signaling. Oncogene. In press.
1. Dilmanian FA
2. Jenkins AL
3. Olschowka JA
4. Zhong Z
5. Park JY
6. Desnoyers NR
7. Sobotka S
8. Fois GR
9. Messina CR
10. Morales M
11. Hurley SD
12. Trojanczyk L
13. Ahmad S
14. Shahrabi N
15. Coyle PK
16. Meek AG
17. O'Banion MK
(2013 Jan 01). X-ray microbeam irradiation of the contusion-injured rat spinal cord temporarily improves hind-limb function. Radiat Res. 179, 76-88.
1. Dilmanian FA
2. Rusek A
3. Fois GR
4. Olschowka J
5. Desnoyers NR
6. Park JY
7. Dioszegi I
8. Dane B
9. Wang R
10. Tomasi D
11. Lee H
12. Hurley SD
13. Coyle PK
14. Meek AG
15. O'Banion MK
(2012 Oct 01). Interleaved carbon minibeams: an experimental radiosurgery method with clinical potential. Int J Radiat Oncol Biol Phys. 84, 514-9.
1. Hein AM
2. O'Banion MK
(2012 Mar 01). Neuroinflammation and cognitive dysfunction in chronic disease and aging. J Neuroimmune Pharmacol. 7, 3-6.
1. Matousek SB
2. Ghosh S
3. Shaftel SS
4. Kyrkanides S
5. Olschowka JA
6. O'Banion MK
(2012 Mar 01). Chronic IL-1β-mediated neuroinflammation mitigates amyloid pathology in a mouse model of Alzheimer's disease without inducing overt neurodegeneration. J Neuroimmune Pharmacol. 7, 156-64.
1. Hein AM
2. Zarcone TJ
3. Parfitt DB
4. Matousek SB
5. Carbonari DM
6. Olschowka JA
7. O'Banion MK
(2012 Mar 01). Behavioral, structural and molecular changes following long-term hippocampal IL-1β overexpression in transgenic mice. J Neuroimmune Pharmacol. 7, 145-55.
1. Wu MD
2. Hein AM
3. Moravan MJ
4. Shaftel SS
5. Olschowka JA
6. O'Banion MK
(2012 Feb 01). Adult murine hippocampal neurogenesis is inhibited by sustained IL-1β and not rescued by voluntary running. Brain Behav Immun. 26, 292-300.
1. Cherry JD
2. Liu B
3. Frost JL
4. Lemere CA
5. Williams JP
6. Olschowka JA
7. O'Banion MK
(2012 Jan 01). Galactic cosmic radiation leads to cognitive impairment and increased aβ plaque accumulation in a mouse model of Alzheimer's disease. PLoS One. 7, e53275.
1. Kyrkanides S
2. Brouxhon SM
3. Tallents RH
4. Miller JN
5. Olschowka JA
6. O'Banion MK
(2012 Jan 01). Conditional expression of human β-hexosaminidase in the neurons of Sandhoff disease rescues mice from neurodegeneration but not neuroinflammation. J Neuroinflammation. 9, 186.
1. O'Banion MK
(2011 Nov 15). Acute neuroinflammation and neurogenesis: a role for microglial COX-1. Cell Cycle. 10, 3819-20.
1. Moravan MJ
2. Olschowka JA
3. Williams JP
4. O'Banion MK
(2011 Oct 01). Cranial irradiation leads to acute and persistent neuroinflammation with delayed increases in T-cell infiltration and CD11c expression in C57BL/6 mouse brain. Radiat Res. 176, 459-73.
1. Kyrkanides S
2. Tallents RH
3. Miller JN
4. Olschowka ME
5. Johnson R
6. Yang M
7. Olschowka JA
8. Brouxhon SM
9. O'Banion MK
(2011 Jan 01). Osteoarthritis accelerates and exacerbates Alzheimer's disease pathology in mice. J Neuroinflammation. 8, 112.
1. Andersen OS
2. O'Banion MK
(2010 Oct 01). Medical Scientist Training Programs: federal funding offers support and drives innovation. Acad Med. 85, 1559.
1. Heneka MT
2. O'Banion MK
3. Terwel D
4. Kummer MP
(2010 Aug 01). Neuroinflammatory processes in Alzheimer's disease. J Neural Transm. 117, 919-47.
1. Matousek SB
2. Hein AM
3. Shaftel SS
4. Olschowka JA
5. Kyrkanides S
6. O'Banion MK
(2010 Jul 01). Cyclooxygenase-1 mediates prostaglandin E(2) elevation and contextual memory impairment in a model of sustained hippocampal interleukin-1beta expression. J Neurochem. 114, 247-58.
1. O'Banion MK
(2010 Apr 01). Prostaglandin E2 synthases in neurologic homeostasis and disease. Prostaglandins Other Lipid Mediat. 91, 113-7.
1. Hein AM
2. Stasko MR
3. Matousek SB
4. Scott-McKean JJ
5. Maier SF
6. Olschowka JA
7. Costa AC
8. O'Banion MK
(2010 Feb 01). Sustained hippocampal IL-1beta overexpression impairs contextual and spatial memory in transgenic mice. Brain Behav Immun. 24, 243-53.
1. Moore AH
2. Wu M
3. Shaftel SS
4. Graham KA
5. O'Banion MK
(2009 Dec 29). Sustained expression of interleukin-1beta in mouse hippocampus impairs spatial memory. Neuroscience. 164, 1484-95.
1. Hein AM
2. O'Banion MK
(2009 Aug 01). Neuroinflammation and memory: the role of prostaglandins. Mol Neurobiol. 40, 15-32.
1. Kyrkanides S
2. Yang M
3. Tallents RH
4. Miller JN
5. Brouxhon SM
6. Olschowka JA
(2009 Apr 30). The trigeminal retrograde transfer pathway in the treatment of neurodegeneration. J Neuroimmunol. 209, 139-42.
1. Ahn J
2. Nguyen FT
3. Mann JR
4. O'Banion MK
(2009 Apr 01). Restructuring MD-PhD programs: career training or broad education? Acad Med. 84, 407; author reply 407-8.
1. Kyrkanides S
2. Miller AW
3. Miller JN
4. Tallents RH
5. Brouxhon SM
6. Olschowka ME
7. O'Banion MK
8. Olschowka JA
(2008 Oct 15). Peripheral blood mononuclear cell infiltration and neuroinflammation in the HexB-/- mouse model of neurodegeneration. J Neuroimmunol. 203, 50-7.
1. Fiorentino PM
2. Tallents RH
3. Miller JN
4. Brouxhon SM
5. O'Banion MK
6. Puzas JE
7. Kyrkanides S
(2008 Oct 01). Spinal interleukin-1beta in a mouse model of arthritis and joint pain. Arthritis Rheum. 58, 3100-9.
1. Zhong Z
2. Deane R
3. Ali Z
4. Parisi M
5. Shapovalov Y
6. O'Banion MK
7. Stojanovic K
8. Sagare A
9. Boillee S
10. Cleveland DW
11. Zlokovic BV
(2008 Apr 01). ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration. Nat Neurosci. 11, 420-2.
1. Shaftel SS
2. Griffin WS
3. O'Banion MK
(2008 Jan 01). The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective. J Neuroinflammation. 5, 7.