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papers of willard m. allen, m.d.

Introduction

Willard Myron Allen (1904-1993) was a 1932 graduate of the University of Rochester School of Medicine & Dentistry and a member of its faculty until his appointment as Chairman of the Department of Obstetrics & Gynecology at Washington University (St. Louis) in 1940. Allen was renowned for his research on female hormones, including his collaboration with George W. Corner on the isolation of progesterone. The Papers of Willard M. Allen were presented by his daughter Lucille Anderson to the Edward G. Miner Library in the summer of 2002. Processing was completed in September 2004. The collection comprises twenty-five boxes and occupies fourteen linear feet.

Biographical Data

Willard Myron Allen was born in Macedon, N.Y. on 5 November 1904 to Lewis F. Allen and Marion E. Hoag. After receiving his undergraduate degree from Hobart College (Geneva, N.Y.) in 1926, Allen enrolled in the second class of the University of Rochester School of Medicine & Dentistry. At the end of his first year, Allen accepted a two-year research fellowship (1927-29) in the laboratory of anatomy department chairman George Washington Corner (1889-1981). Upon completion of his fellowship, Allen returned to his medical studies and graduated with the Class of 1932.

Allen remained in Rochester in 1932-33 as a National Research Council fellow and assistant resident pathologist. In 1933-34 he interned at Strong Memorial Hospital, the University’s teaching hospital. He did his residencies (1934-37) in the Dept. of Obstetrics & Gynecology at Strong. Allen was made an instructor in the School of Medicine in 1936, and assistant professor of obstetrics & gynecology in 1938. He held this position until his appointment in 1940 as chairman of the Dept. of Obstetrics & Gynecology at Washington University School of Medicine (St. Louis). Allen was the first Rochester medical graduate to attain this professorial rank, and at the time was one of the youngest department chairmen in an American medical school. Allen served as chair of obstetrics & gynecology at Washington University and as obstetrician-in-chief at Barnes and Allied Hospitals until his retirement in 1971. That year Allen left St. Louis for Baltimore, where he was appointed professor of obstetrics at the University of Maryland. Allen subsequently served as associate dean of the medical school at Maryland (1976-1982).

Late in his first year of medical school (1927), Allen was invited by George W. Corner to become a fellow in anatomy and to work with him on the identification of the hormone responsible for progestational changes. By the end of 1928 Corner and Allen had made hundreds of extracts from the corpus luteum of rabbits and in the process had isolated the hormone later to be named progesterone. Their work was described in a classic paper, “Physiology of the corpus luteum,” published in the American Journal of Physiology (1929, 88:326-46). Allen also described this work in the thesis submitted for his masters degree on 17 May 1929 entitled The preparation of a hormone of the corpus luteum which produced progestational proliferation (Box 14, Folder 9).

The female hormones would remain the focus of Allen's research the remainder of his career. This research is described in an autobiographical article entitled “Recollections of my life with progesterone,” published in Gynecologic Investigation (1974, 5:142-182). Allen was the first to administer progesterone to human subjects – specifically for the treatment of dysfunctional uterine bleeding (1942); developed “Allen’s blue reaction” (the blue color test for DHIA) and its clinical application (1950); specified the role of progesterone in the maintenance of pregnancy, etc. Allen's best known contribution outside the laboratory is his description of what has been termed the “Allen-Masters Syndrome,” i.e., the laceration of the fascial layers of the broad and Mackenrodt ligaments resulting in abnormal mobility of the cervix. This condition was described by Allen and William H. Masters in their paper “Traumatic laceration of uterine support: the clinical syndrome and operative treatment,” published in the American Journal of Obstetrics and Gynecology (1955, 70:500-513).

In 1927 Allen married Julia Bell Gardner (d. 1941). A daughter (Lucille) was born to them in 1933. In 1946 Allen married Dorothy Dunn Esley. Willard Myron Allen died in Baltimore on 15 August 1993.

Organization of the Collection


General Files (Boxes 1-8)

The General Files are an alphabetically arranged series that reflect Allen’s various activities from the late 1920s through the early 1990s. It includes materials pertaining to medical and scientific societies; extensive correspondence with pharmaceutical companies involved in the manufacture of hormonal extracts; and Allen's participation in governmental or organizational review committees (e.g., the FDA’s committee on the oral contraceptive Enovid). Material on academic matters at the University of Rochester or Washington University is limited.

Correspondence (Boxes 9-10)

Allen’s correspondence is arranged alphabetically by correspondent. (His extensive correspondence with pharmaceutical companies is organized in the General Files under each firm’s name.)

Talks and Publications (Boxes 11-13)

This series is interesting, but by no means complete. For example, there is not a complete set of Allen’s reprints in the collection; nor are most of the talks and lectures given over half a century present. Many manuscripts, reprints and texts of oral presentations are here, however, including the manuscripts of several articles that were never published.

Research (Boxes 14-23)

The research series may be divided into two unequal parts. The first (Boxes 14-15) contains the laboratory notebooks in which Allen recorded the preparation of more than 100 hormonal extracts at the University of Rochester between 1929 and 1936. The second part of this series records clinical research conducted at Washington University from the early 1940s. Because the St. Louis files include patient health information, researchers needing access to Boxes 14-23 will require permission from the University of Rochester Medical Center’s HIPAA officer.

Diplomas, Certificates, Awards, etc. (Boxes 24-25)

In addition to diplomas, certificates and awards, Box 25 also includes photographic portraits of Willard M. Allen.

Inventory of the Papers of Willard M. Allen


Box One: General Files

  • Folder 1: Curriculum vitae of Willard M. Allen
  • Folder 2: American Association of Obstetricians & Gynecologists (1972-77)
  • Folder 3: American Chemical Society (1935)
  • Folder 4: American College of Obstetricians & Gynecologists. Certificate of appreciation (1974)
  • Folder 5: American College of Obstetricians & Gynecologists. Distinguished service award (1980)
  • Folder 6: American Gynecological Society (1972-75)
  • Folder 7: American Medical Association. Advisory committee on nomenclature of endocrine principles (1935-40)
  • Folder 8: American Medical Association. Advisory committee on nomenclature of endocrine principles (1935-40)
  • Folder 9: American Medical Association. Subcommittee on diabetes and pregnancy wastage (1952)
  • Folder 10: American Medical Association. Subcommittee on diabetes and pregnancy wastage (1953-54)
  • Folder 11: American Medical Association. Subcommittee on diabetes and pregnancy wastage (1955)
  • Folder 12: American Medical Association. Subcommittee on diabetes and pregnancy wastage (1956)
  • Folder 13: American Medical Association. Subcommittee on diabetes and pregnancy wastage (1957)
  • Folder 14: American Medical Association. Fifty year club (1985)
  • Folder 15: American Society for the Study of Sterility (15th annual meeting: 1955: Atlantic City)
  • Folder 16: Ayerst, McKenna and Harrison (1937-39)
  • Folder 17: Ayerst, McKenna and Harrison (1940-49)

Box Two: General Files

  • Folder 1: Ayerst, McKenna and Harrison (1950-61)
  • Folder 2: Carnick and Co. (1938-40)
  • Folder 3: Ciba Pharmaceutical Products (1938-44)
  • Folder 4: Club for Research on Aging (1939)
  • Folder 5: Club for Research on Aging (1940)
  • Folder 6: Club for Research on Aging (1941)
  • Folder 7: Club for Research on Aging (1942)
  • Folder 8: Club for Research on Aging (1943-44)
  • Folder 9: DES litigation (1977)
  • Folder 10: Eli Lilly Co. (1936-49)
  • Folder 11: Encuentro  Internacional de Ginecologia y Obstetricia (1st annual meeting: 1982: Monterrey, Mexico)
  • Folder 12: Food and Drug Administration. Committee on Enovid. Correspondence (Jan. 1963
  • Folder 13: Food and Drug Administration. Committee on Enovid. Correspondence (Feb.-Mar. 1963)
  • Folder 14: Food and Drug Administration. Committee on Enovid. Correspondence (April 1963)

Box Three: General Files

  • Folder 1: Food and Drug Administration. Committee on Enovid. Correspondence (May-Sep 1963)
  • Folder 2: Food and Drug Administration. Committee on Enovid. Responses from physicians solicited for data (Mar-Apr 1963)
  • Folder 3: Food and Drug Administration. Committee on Enovid. Data on patients in St. Louis who took Enovid in 1962 (1963)
  • Folder 4: Food and Drug Administration. Committee on Enovid. Summary data
  • Folder 5: Food and Drug Administration. Committee on Enovid. G.D. Searle & Co. report (2 Apr 1963)
  • Folder 6: Food and Drug Administration. Committee on Enovid. Searle publications on Enovid
  • Folder 7: Food and Drug Administration. Committee on Enovid. Final report (12 Sep 1963)
  • Folder 8: Food and Drug Administration. Committee on Enovid. Irwin C. Winter. “Contents of Book B” (1963?)
  • Folder 9: Food and Drug Administration. Committee on Enovid. Transcript of Senator Gruening’s meeting (7 Aug 1963)
  • Folder 10: Food and Drug Administration. Fertility and maternal health drugs advisory committee (1983)
  • Folder 11: FASEB. Dedication of new wings of the Milton O. Lee Building (1987)
  • Folder 12: Genesee Hospital, Rochester, N.Y. Tatelbaum lecture (1971)
  • Folder 13: Germany. Photographs of visit to the Schering Laboratories in Berlin (1954)
  • Folder 14: Harter, Calhoun and Williams. Lutrexin case (1974)

Box Four: General Files

  • Folder 1: Hobart College. Correspondence (1988-92)
  • Folder 2: Hobart College. 50th anniversary reunion (1976)
  • Folder 3: Hobart College. Alumni association (1992)
  • Folder 4: Hynson, Westcott and Dunning. Lutein tablets legal action (1938-39)
  • Folder 5: Hynson, Westcott and Dunning. Lutein tablets legal action  (1939-42)

Box 5: General Files

  • U.S. District Court. Southern District of New York. United States of America vs. 6 boxes, more or less, each containing one dozen tubes of Lutein tablets. Hynson, Westcott and Dunning … New York, April 4, 1940. Stenographer’s minutes.

Box 6: General Files

  • Folder 1: International Symposium on the Pregnant Uterus (3rd: 1991: Debrecen, Hungary)
  • Folder 2: League of Nations. Meetings on standardization of sexual hormones (1935: London)
  • Folder 3: Los Alamos Hospital (1947-58)
  • Folder 4: Memberships
  • Folder 5: Merck and Company (1933-41)
  • Folder 6: Wm. S. Merrell Co. (1943-49)
  • Folder 7: Wm. S. Merrell Co. (1951-57)
  • Folder 8: Wm. S. Merrell Co. Tace Symposium (1952: Cincinnati)
  • Folder 9: Wm. S. Merrell Co. MER-25, an estrogen antagonist
  • Folder 10: National Institute of Neurological Diseases and Blindness. Ad hoc committee to review the perinatal research program (1965-66)
  • Folder 11: National Research Council (1931-34)
  • Folder 12: New York Academy of Sciences. Conference on biochemical actions of progesterone and progestins (1976)
  • Folder 13: Organon Inc. (1960)
  • Folder 14: Pan-Pacific Surgical Association Congress (13th: Honolulu: 1975)
  • Folder 15: Parke Davis and Co. (1931-38)
  • Folder 16: Perinatology-Neonatology. WMA cover and profile (May/June 1980)
  • Folder 17: Pharmacopoeia of the United States of America. Progesterone correspondence (1938-48)
  • Folder 18: Rockefeller Foundation. General Education Board (1934-36)

Box Seven: General Files

  • Folder 1: Schering Corp. Correspondence (1934-37)
  • Folder 2: Schering Corp. Correspondence (1938-39)
  • Folder 3: Schering Corp. Correspondence (1940-41)
  • Folder 4: Schering Corp. Correspondence (1942-44)
  • Folder 5: Schering Corp. Correspondence (1968)
  • Folder 6: Sharpe and Dohme (1954-58)
  • Folder 7: Sinai Hospital of Detroit. Alfred I. Sherman Resident Society (1973)
  • Folder 8: Société Française de Gynecologie (30th meeting: 1981: Clermont-Ferrand) [see also “Allen-Masters Syndrome Revisted,” Box 13/3]
  • Folder 9: Society for Gynecologic Investigation. Distinguished Achievement Award (1983)
  • Folder 10: E.R. Squibb and Sons (1954-55)
  • Folder 11: E.R. Squibb and Sons (1956)
  • Folder 12: E.R. Squibb and Sons (1957)
  • Folder 13: E.R. Squibb and Sons (1958-65)

Box Eight: General Files

  • Folder 1: E.R. Squibb and Sons (1866-69)
  • Folder 2: University of Rochester. Doctor of science honoris causa (1957)
  • Folder 3: University of Rochester. Trustees (1960-70)
  • Folder 4: University of Rochester. Inauguration of Dennis O’Brien (1984)
  • Folder 5: University of Rochester. School of Medicine and Dentistry. Letters of appointment (1927-39)
  • Folder 6: University of Rochester. School of Medicine and Dentistry. WMA’s cesarean section deliveries
  • Folder 7: University of Rochester. School of Medicine and Dentistry. Correspondence (1959-91)
  • Folder 8: University of Rochester. School of Medicine and Dentistry. Corner-Mason Seminar Room (1973)
  • Folder 9: University of Rochester. School of Medicine and Dentistry. 36th annual reunion alumni lecture (1980)
  • Folder 10: University of Rochester School of Medicine and Dentistry. Alumni reunions (1987, 1991, 1992)
  • Folder 11: Washington University. School of Medicine. Appointment (1939-40)
  • Folder 12: Washington University. School of Medicine. Letters of congratulation on appointment as professor of obstetrics (1939-40)
  • Folder 13: Washington University. School of Medicine. Visitors (1957-58)
  • Folder 14: Washington University. School of Medicine. Vital statistics re: OB/GYN service, 1927-66
  • Folder 15: Washington University. Correspondence
  • Folder 16: Willard Allen Resident Society (1971)

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Box Nine: Correspondence

  • Folder 1: General correspondence A-E
  • Folder 2: General correspondence F-J
  • Folder 3: General correspondence K-M
  • Folder 4: General correspondence N-S
  • Folder 5: General correspondence T-Z
  • Folder 6: Arneson, A. N. (1971-86)
  • Folder 7: Atwell, Wayne J. (1939)
  • Folder 8: Auerbach, Larry Scott (1992)
  • Folder 9: Bradbury, James T. (1976-86)
  • Folder 10: Collison, David B. (1939)
  • Folder 11: Corner, George W. Correspondence re: progesterone nomenclature (1962)
  • Folder 12: Corner, George W. (1975-81)
  • Folder 13: Crenshaw, Carlyle (1980-86)
  • Folder 14: Csapo, Arpad (1963-83)
  • Folder 15: Friedrich, Ernst R. (1972-91)
  • Folder 16: Hartman, Carl G. (1932, 1939)
  • Folder 17: Haskins, Arthur L. (1947-49, 1976-82)

Box Ten: Correspondence

  • Folder 1: Haterius, Hans C. (1933-39)
  • Folder 2: Hoffman, Friedrich (1934-35)
  • Folder 3: Horvath, A. A. (1935-37)
  • Folder 4: Karnaky, Karl John (1970-84)
  • Folder 5: King, M. Kenton (1972-89)
  • Folder 6: Klopper, Arnold (1971-76)
  • Folder 7: Longo, Lawrence D. (1971-82)
  • Folder 8: Mikhail, Girgis (1972-84)
  • Folder 9: Parkes, Alan (1962)
  • Folder 10: Ponder, Eric (1937)
  • Folder 11: Reynolds, S. R. M. (1974-77)
  • Folder 12: Simmer, Hans (1968-86)
  • Folder 13: Smith, George V. (1935-40)
  • Folder 14: Smith, Thomas W. (1980-81)
  • Folder 15: Speert, Harold (1980)
  • Folder 16: Sweet, Frederick (1981-89)
  • Folder 17: Sweet, Frederick (1991)
  • Folder 18: Tausk, M. (1931-67)
  • Folder 19: Tsuei, Julia J. (1972-73)
  • Folder 20: Veldhuis, Andrew (1950-51)
  • Folder 21: Wangensteen, Owen H. (1975)
  • Folder 22: Westphal, Ulrich (1980)
  • Folder 23: Wiest, Walter G. (1973-76)
  • Folder 24: Woolf, Ralph (1973)

Box Eleven: Talks, Publications and Papers

  • Folder 1: Partial list of WMA ’s lectures, 1936-1950
  • Allen Papers
  • Folder 2: “ Some effects of estrin and progestin in the rabbit, ” IN: Cold SprinAllen Papersg Harbor symposia on q
  • Folder 3: “Duration of sensitivity of the endometrium during lactation in the rat” (1938)
  • Folder 4: “Physiology of the vagina ” [not published] (ca. 1938)
  • Folder 5: Sex and internal secretions [ed. by WMA]. Baltimore, 1939. Correspondence with contributors
  • Folder 6: “Bioassay of progesterone” [U.S. Pharmacopoeial Conference] (May 1940)
  • Folder 7: “Endocrine factors in gynecological disease” [Cleveland] (Oct. 1940)
  • Folder 8: “Effect of progesterone in adolescent girls and young women with functional utrine bleeding” (1942)
  • Folder 9: "The ovarian hormones and their clinical use” (1942)
  • Folder 10: “Treatment of amenorrhea with progesterone and anhydrohydroxy progesterone” (1943)
  • Folder 11: “Excretion of neutral 17-ketosteroids in two cases of male pseudohermaphroditism” (1946)
  • Folder 12: “Stability of natural progesterone” (1948)
  • Folder 13: “Color test for dehydroisoandrosterone and closely related steroids” (1950)
  • Folder 14: “Functional uterine bleeding” [Southern Medical Association, St. Louis] (1950)
  • Folder 15: “A simple method for analyzing absorption curves of use in the colorimetric determination of urinary steroids” (1950)
  • Folder 16: “Paper chromatography of conjugated urinary steroids” [not published] (1951)

Box Twelve: Talks, Publications and Papers

  • Folder 1: “Uses and abuses of hormone therapy” (1951)
  • Folder 2: “The mathematical development of the formulae essential to the intelligent use of countercurrent separations where the number of passes is less than twenty-five” [National Academy of Sciences meeting, St. Louis] (1952)
  • Folder 3: “Hormonal control of menstruation” (1954)
  • Folder 4: “Endocrine  therapy in gynecology” [Interstate Postgraduate Medical Association of North America, Milwaukee] (1955)
  • Folder 5: “Study of steroid color reaction  by Allen’s blue color test” [not published] (ca. 1950)
  • Folder 6: “Five-year analysis of cesarean sections at the St. Louis Maternity Hospital, 1956-1960” [not published]
  • Folder 7: Progestins in the human [contract with Georg Thieme Verlag] (1960)
  • Folder 8: “Maintenance of pregnancy in castrated rabbits by 6-alpha-methyl 17-alpha-hydroxy  progesterone” (1961)
  • Folder 9: “Endocrinology in pregnancy” [New York Obstetrical Society] (1963)
  • Folder 10: Initiation of Labor Conference [Princeton, N.J.] (Dec. 1963)
  • Folder 11: “Internal bleeding” [2nd ed. of Zander monograph] (1963)
  • Folder 12: “Ovarian function in human pregnancy” [Endocrine Society, San Francisco] (1964)
  • Folder 13: “Use of progestational agents in habitual abortion” [Wyoming State Medical Society] (1964)
  • Folder 14: Discussion of paper by Arthur Haskins [American Gynecological Society] (May 1968)
  • Folder 15: “Ovarian resection in the Stein-Leventhal syndrome” (1968)
  • Folder 16: “Progesterone in retrospect” [Louisiana Obstetrical & Gynecological Society] (1968)
  • Folder 17: “Possible hazards in the administration of estrogen” (1969)
  • Folder 18: “George W. Corner: reflections and recollectons, 1926-1940” [American Association of Anatomists] (197?)
  • Folder 19: Abortion statement (1970)
  • Folder 20: “Chronic pelvic congestion and pelvic pain” (1970)
  • Folder 21: “Progesterone and the pill” (1970)
  • Folder 22: “Progesterone: how did the name originate?” (1970)
  • Folder 23: “Stein-Levanthal syndrome and the results of bilateral ovarian medullary resection” [not published] (1971)
  • Folder 24: “Progesterone ‘receptor’ in normal and abnormal human uterine tissue” (1973)
  • Folder 25: “Pros and cons of estrogen therapy for gynecologic conditions” (1973)
  • Folder 26: “Recollections of my life with progesterone” (1974)
  • Folder 27: ”Recollections of my life with progesterone” [illustrations] (1974)

Box Thirteen: Talks, Publications and Papers

Allen Papers

  • Folder 1: “Stein-Levanthal syndrome” (1974)
  • Folder 2: Current contents “citation classic&rdqu; Allen Papers; (1979)
  • Folder 3: “The Allen-Masters syndrome revisited” (1981) [ see also Société Française de Gynecologie, Box 7/8 ]
  • Folder 4: Obituary of G.W. Corner for the Transactions of the American Gynecological and Obstetrical Society (1982)
  • Folder 5: “Fifty years of progesterone” (1986)
  • Folder 6: Letter to the editor of the Journal of the University of Rochester Medical Center (1992)
  • Folder 7: Discussion of Carl Kaufmann paper (no date)
  • Folder 8: Miscellaneous reprints

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Box Fourteen: Research

  • Folder 1: Laboratory notebook II. Extracts #57-69 (1929-30)
  • Folder 2: Laboratory notebook III. Extracts #70-81 (1930)
  • Folder 3: Laboratory notebook IV. Extracts #82-92 (1930-32)
  • Folder 4: Laboratory notebook V. Extracts #92-98 (1932)
  • Folder 5: Laboratory notebook. Extracts #99-104 (1933-34)
  • Folder 6: Laboratory notebook. Extracts #103, 105-113 (1933-35)
  • Folder 7: Laboratory notebook. Purification only. Extracts #103-110 (1933-34)
  • Folder 8: Laboratory notebook. Extract #114 (1935-36)
  • Folder 9: Masters thesis (1929)

Box Fifteen: Research

  • 11 small bottles containing laboratory and commercial extracts (1930s)

Box Sixteen: Research

  • Folder 1: Estrogen studies. Chiefly methods and formulae (1941-43)
  • Folder 2: Pregnancy urine. Patient GWH (1941)
  • Folder 3: Adrenal tumor studies. Patient EB (1942)
  • Folder 4: Pregnancy. Premature delivery. NaPG, estrogen and estriol studies. Patient GW (1942)
  • Folder 5: Dehydro 150 and rosterone studies. Adrenal tumors, female pseudohermaphroditism, Cushing’s disease, pregnancy (1942-49)
  • Folder 6: Isolation studies. Patient EL (1942-52)
  • Folder 7: Female pseudohermaphroditism. Patient FA (1944-52)
  • Folder 8: Graph of NaPG and urinary nitrogen. Patient KS (1945)

Box Seventeen: Research

  • Folder 1: Isolation studies. Patient KLB (1945-52)
  • Folder 2: Pregnancy data (1946-50)
  • Folder 3: Isolation studies. Patient LC (1946-53)
  • Folder 4: Abdominal pregnancy. Patient JD (1946)
  • Folder 5: Estrogen NaPG method used prior to 1947
  • Folder 6: Female pseudohermaphroditism. Patient SE (1947)
  • Folder 7: Adrenal tumor. Patient DZ (1947)
  • Folder 8: Adrenal tumor studies. Patient MO (1947-48)
  • Folder 9: “C.” Patient LAN (1949-50)
  • Folder 10: Isolation experiments. NaPG, estriol (1949-50)
  • Folder 11: Patient data (1949-50)
  • Folder 12: NaPG graph. Patient K (1950)
  • Folder 13: Adrenal tumor. Patient B (1950)

Box Eighteen: Research

  • Folder 1: Abdominal pregnancy. Patient JMD (1950)
  • Folder 2: Patients MR, JMD, H, S (1950-51)
  • Folder 3: Adrenal tumor studies. Patient ML (1950-51)
  • Folder 4: Adrenal tumor studies. Patient JS [with left ovarion tumor] (1950-53)
  • Folder 5: Countercurrent book I (1950-59)
  • Folder 6: Countercurrent book II (1954-71)
  • Folder 7: Adrenal tumor studies. Patient BW (1952)
  • Folder 8: Patients FB and others (1952-54)
  • Folder 9: NaPG (1953)
  • Folder 10: Pregnancy urine. Estriol glucuronide distribution (1953)
  • Folder 11: Adrenal tumor studies. Patient CE (1953)
  • Folder 12: Pregnancy urine. Last month of pregnancy (1953-54)
  • Folder 13: Original pregnancy urine extracts (1953-55)
  • Folder 14: Pregnancy urine. Countercurrent distribution B (1955)
  • Folder 15: Adrenal tumor. DHA sulfate (1956)
  • Folder 16: NaPG, NaEG studies (1957-58)

Box Nineteen: Research

  • Folder 1: PURT (1958)
  • Folder 2: Standard curves. Progesterone (1956)
  • Folder 3: PURT analysis (1959)
  • Folder 4: PURT. Kober test curves, NaPG fractions, Zimmerman tests and blue color tests (1960)
  • Folder 5: Zimmerman fractions, blue color curves (Nov. 1960)
  • Folder 6: PURT. Recrystallization of white NaPG fractions (1960)
  • Folder 7: Blue color curves BuOH 80, .01N NaOH 160 (1960-61)
  • Folder 8: PURT. Kober test, countercurrent BuOH 80, .01N NaOH 160 (1960-61)
  • Folder 9: PURT countercurrent BuOH 80, .01N NaOH 160 (1960-61)
  • Folder 10: PURT countercurrent BuOH 80, .01N NaOH 160 (1960-61)
  • Folder 11: Abdominal pregnancy. Patient BH (1961)
  • Folder 12: Abdominal pregnancy. NaHEG study. Patient BH (1961)
  • Folder 13: Abdominal pregnancy. Estrogen fraction. Patient BH (1961)
  • Folder 14: Abdominal pregnancy. Estriol (alkali fractions). Patient BH (1961)
  • Folder 15: Abdominal pregnancy. Column chromatography. Estrogen fractions. Patient BH (1961)
  • Folder 16: Abdominal pregnancy. Estrogen fraction, celite partition. Patient BH (1961-62)
  • Folder 17: Abdominal pregnancy. NaPG (neutral fraction). Patient BH (1961)
  • Folder 18: Abdominal pregnancy. Summary sheet for all specimens. Patient BH
  • Folder 19: Abdominal pregnancy. Ultra violet and Kober curves. Estrogen fraction, celite (1962)
  • Folder 20: Patient BH. NaPG (neutral fraction), Zimmerman test curves (1961)
  • Folder 21: Patient BH. Estrogen (alkali) fraction (1961)
  • Folder 22: Patient BH. NaPG fraction (neutral), Kober curves, column chromatography tubes 1-70 (1961)
  • Folder 23: Patient BH data (1961)
  • Folder 24: Normal pregnancy. Patient EC (1962)

Box Twenty: Research

  • Folder 1: NaPG methods, orceinol, etc. Patient BH (1964-66)
  • Folder 2: “P.” NaPG workup (1964)
  • Folder 3: Countercurrent separation of progesterone, testosterone, vinyltestosterone (1965-66)
  • Folder 4: Orceinol methods for NaPG (1965)
  • Folder 5: Abdominal pregnancy charts (1966)
  • Folder 6: Countercurrent math presentation (1966)
  • Folder 7: Countercurrent equipment (1966-68)
  • Folder 8: Countercurrent separation of 20-alpha and 20-beta progesterone (1966-67)
  • Folder 9: Patient MR (1967?)
  • Folder 10: Urinary data. Final summary and graph for NaPG. Patient MR (1967-70)
  • Folder 11: Patient MR. NaPG fractions 3-16
  • Folder 12: Patient MR. Fractions 22, 17
  • Folder 13: Patient MR completed. Fractions 17, 22, 23

Box Twenty-One: Research

  • Folder 1:Patient MR. Fractions 27-30 (1968)
  • Folder 2:Patient MR. Fractions 31-34, 37, 38, 50A 42 (1968-70)
  • Folder 3:Patient MR. Fractions 51, 48, 46, 44, 43 complete (1969-70)
  • Folder 4:Patient MR. Fraction 66
  • Folder 5:Patient MR. Fractions 66, 65, 63, 56, 59, 54A, 52 complete (1969-71)
  • Folder 6:Patient MR. Analyses and computations (1970)
  • Folder 7:Patient MR. Final summary sheets
  • Folder 8: Orceinol methods, also Patient MR NaPG-XG data (1971)

Box Twenty-Two: Research

  • Folder 1: Countercurrent papers (1960s-1970s)
  • Folder 2: Graphs for countercurrent mathematics
  • Folder 3: Equations for two unknowns. Countercurrent analysis
  • Folder 4: Countercurrent analyses for A-subscript 1, A-subscript2, K-subscript 1, K-subscript 2 (1972)
  • Folder 5: Development of formulae for K-subscript 1, etc. (1980)
  • Folder 6: Serial addition for calculating A-subscript 1, etc. (1981-82)
  • Folder 7: Countercurrent. Summarized development (no date)
  • Folder 8: Blue color test method (no date)

Box Twenty-Three: Research Photography

  • Envelope 1: Patient LB. Tubal pregnancy, dead foetus in tube (1946)
  • Envelope 2: Patient DB. Congenital height disease (1963)
  • Envelope 3: Patient FB. Cushing’s syndrome (1948-52)
  • Envelope 4: Patient MB. Cushing’s disease (1956-57)
  • Envelope 5: Patient C. (1955)
  • Envelope 6: Patient EC. Double uterus twin pregnancy (1954)
  • Envelope 7: Patient DC (1961)
  • Envelope 8: Patient JC. True hermaphrodite. Left adnexus, left gonad, right gonad (1959)
  • Envelope 9: Patient MC. Twin abdominal pregnancy (1959)
  • Envelope 10: Patient JD. Abdominal pregnancy (1946-47)
  • Envelope 11: Patient CD. Feminizing tumor left ovary, precocious puberty (1957)
  • Envelope 12: Patient JD. Abdominal pregnancy (1957)
  • Envelope 13: Patient JD. Abdominal pregnancy, placenta not removed (1950)
  • Envelope 14: Patient WD. Virilizing patient (1957)
  • Envelope 15: Patient CE. Adenal tumor (1953)
  • Envelope 16: Patient RF (1958)
  • Envelope 17: Patient CF. Precocious puberty (1958)
  • Envelope 18: Patient RG (1951)
  • Envelope 19: Patient BH. Abdominal pregnancy (1961)
  • Envelope 20: Patient CJ. Leydig cell tumor (1961)
  • Envelope 21: Patient SK. Turner’s syndrome (1960)
  • Envelope 22: Patient BK. Precocious puberty (1960)
  • Envelope 23: Patient ML after removal of tumor (1950-53)
  • Envelope 24: Patient JL (1958)
  • Envelope 25: Patient PL (1954)
  • Envelope 26: Patient CM. True hermaphrodite (1957)
  • Envelope 27: Patient BM. Precious puberty (1960)
  • Envelope 28: Patient BM. Arrhens blastoma (1951)
  • Envelope 29: Patient ER. Eclampsia before and after (1948)
  • Envelope 30: Patient PR. Precious puberty (1948-51)
  • Envelope 31: Patient MR. Abdominal pregnancy (1948)
  • Envelope 32: Patient MR in operating room (1948)
  • Envelope 33: Patient DS. Left ovary removed (1960)
  • Envelope 34: Patient S. Leydig cell hyperplasia (1952)
  • Envelope 35: Patient RS. Eclampsia (1948)
  • Envelope 36: Patient DW (1949)
  • Envelope 37: Patients BW, MLR, LB. Turner’s syndrome (1957)
  • Envelope 38: Patient CW. Hyperplasia of adrenal, right adrenal tumor (1957)
  • Envelope 39: Patient CW. Adrenal tumor (1959)
  • Envelope 40: Patient ZD. Tumor (1947-49)
  • Envelope 41: Human parabiotic identical twins (1954)
  • Envelope 42: Anacephalous monster (1962)

Box Twenty-Four: Awards and Medallions

Box Twenty-Five: Awards, Diplomas, Certificates, Photographs

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Portrait of Willard M. Allen

Willard M. Allen, M.D.

How the Collection is Organized

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If you have questions regarding this collection, please contact:

Christopher Hoolihan