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Dean A. Arvan, M.D.

Professor of Pathology and Laboratory Medicine

Laboratory Medicine
Prenatal and Molecular Diagnosis

URMC Labs
601 Elmwood Ave.
Rochester, NY 14642-8626
Dean_Arvan@urmc.rochester.edu

Director of the URMC Clinical Laboratories from 1977 through 1997. Twice Acting Chair of the Department. Senior Associate Dean for Academic Affairs in the School of Medicine and Dentistry from 1998 to 2002. Dr. Arvan was responsible for the consolidation of the URMC Labs into one efficient organization. His clinical interests have been in both the medical and administrative aspects of laboratory operations, with a particular interest and expertise in the appropriate and cost-effective utilization of diagnostic tests. He continues as advisor to the Department and School on administrative and academic issues.

Qualifications

M.D., Hahnemann Medical College 1959
Rotating Internship, St. Agnes Hospital, Philadelphia, PA 1959-60
Residency AP/CP, University of Pennsylvania 1960-64
Board Certification, American Board of Pathology (AP/CP) 1965

Research Overview

Dr. Arvan's research has included collaboration with the Divison of Pediatric Genetics and the Department of Obstetrics and Gynecology in the establishment of the Rochester Regional Maternal Serum Alpha-Fetoprotein Program; evaluation of immunoassays for the detection of oncoprotein expression; and, more recently, evaluation of molecular assays in genetic diseases and cancer.

Publications

Ryan DH, Nuccie BL, Arvan DA. Non-PCR dependent detection of the Factor V Leiden mutation from genomic DNA using a Homogeneous Invader™ microtiter plate assay. Molecular Diagnosis 4(2):135-143, 1999.

Corsetti J, Arvan DA. Acute viral hepatitis. In: Diagnostic strategies for common medical problems. Black ER et. al, eds. pp. 170-180, APC Press, 1999.

Mooney RA, Arvan DA, Saller DN Jr, French CA, Peterson CJ. Decreased maternal serum hCG levels with increasing gravidity and parity. Obstet Gynecol 1995 Dec;86(6):900-5.

Mooney RA, Peterson CJ, French CA, Saller DN Jr, Arvan DA. Effectiveness of combining maternal serum alpha-fetoprotein and hCG in a second-trimester screening program for Down syndrome. Obstet Gynecol. 1994 Aug;84(2):298-303.

Rodewald LE, Woodin KA, Szilagyi PG, Arvan DA, Raubertas RF, Powell KR. Relevance of common tests of cerebrospinal fluid in screening for bacterial meningitis. J Pediatr. 1991 Sep;119(3):363-9.