print

Mahlon D. Johnson, M.D., Ph.D.

Professor of Pathology and Laboratory Medicine

Neuropathology
Leptomeningeal Diseases, Meningiomas,
Tumors of the Central and Peripheral Nervous System

URMC Labs
601 Elmwood Ave., Rm 1-7423D
Rochester, NY 14642-8626
Tel: (585) 276-3087
Fax: (585) 273-1027

Mahlon_Johnson@urmc.rochester.edu

Dr. Johnson has particular interest and expertise in neurosurgical pathology and neurodigenerative disorders. He has published extensively in peer-reviewed journals and receives referrals for consultation from across the U.S.

Qualifications

M.D., University of Tennessee 1981
Ph.D., University of Tennessee 1984
Research Fellow, Cell Biology, University of Texas Health Sciences Center Dallas 1985
Resident in Anatomic Pathology, Vanderbilt University 1984-87
Fellow in Neuropathology, Vanderbilt University, 1987-89
Research Fellow, Cell Bioogy, Vanderbilt University 1989-93
Board Certification, American Board of Pathology (Anatomic Pathology) 1988
American Board of Pathology (Neuropathology) 1989

Research Overview

Dr. Johnson's primary research interest is in the growth regulation of the leptomeninges and meningiomas.

Publications

Atkinson J.A., Johnson M.D., Bouldin, T.W. and Whetsell W.O. Muscle and nerve biopsy (Chapter 54). In Noel Weider, Richard Cote, Saul Suster and Lawerence Weiss (eds.) Modern Surgical Pathology: New York, W.B.Saunders. 2003 and 2009.

Johnson M.D. and Atkinson JA.  Central Nervous System Tumors (Chapter 51). In Noel Weider, Richard Cote, Saul Suster and Lawerence Weiss (eds.) Modern Surgical Pathology: New York, W.B.Saunders, 2009.

Johnson MD, O'Connell M, Vito F, Bakos, RS. Increased STAT-3 and synchronous activation of Raf-1-MEK-1-MAPK, and Phosphatidylinositol 3-Kinase-Akt-mTOR Pathways in Atypical andAnaplastic Meningiomas. J Neurooncol 92 (2):129-36, 2009.

Johnson MD, Sade, B. Milano MT, Lee JH and Toms, SA. New prospects for management and treatment of inoperable and recurrent skull base meningioma. J Neurooncol, 86 (1):109-22, 2008.

Johnson MD, O’Connell M., Vito F. Mesothelin expression in the leptomeninges and meningiomas. J Histochem Ctyochem 56 (6):579-85, 2008.

Majumder SK, Gebhart S, Johnson MD, Thompson R, Lin WC, Mahadevan-Jansen A. A probability-based spectroscopic diagnostic algorithm for simultaneous discrimination of brain tumor and tumor margins from normal brain tissue. Appl Spectrosc. 2007 May;61(5):548-57.

Johnson MD, Fan X, Bourne P, Walters D. Neuronal differentiation and expression of neural epitopes in pituitary adenomas. J Histochem Cytochem. 2007 Dec;55(12):1265-71.

Johnson MD, Sade B, Milano MT, Lee JH, Toms SA. New prospects for management and treatment of inoperable and recurrent skull base meningiomas . J Neurooncol. 2008 Jan;86(1):109-22.

Johnson MD, Stevenson CB, Thompson RC, Atkinson J, Boyer P. December 2006: 31-year-old woman with hemiparesis. Brain Pathol. 2007 Apr;17(2):255-7.

Johnson MD, Floyd JL, Caprioli RM. Proteomics in diagnostic neuropathology. J Neuropathol Exp Neurol. 2006 Sep;65(9):837-45.

Mangels KJ, Johnson MD, Weil RJ. 35-year-old Woman with Progressive Bilateral Leg Weakness. Brain Pathol. 2006 Apr;16(2):183-4.

Johnson M, Toms S. Mitogenic signal transduction pathways in meningiomas: novel targets for meningioma chemotherapy? J Neuropathol Exp Neurol. 2005 Dec;64(12):1029-36.

Stevenson CB, Johnson MD, Thompson RC. Cystic cavernous malformation of the cerebellopontine angle. 2005 Nov;103(5):931.

Toms SA, Lin WC, Weil RJ, Johnson MD, Jansen ED, Mahadevan-Jansen A. Intraoperative optical spectroscopy identifies infiltrating glioma margins with high sensitivity. Neurosurgery. 2005 Oct;57(4 Suppl):382-91; discussion 382-91.

Schwartz SA, Weil RJ, Thompson RC, Shyr Y, Moore JH, Toms SA, Johnson MD, Caprioli RM. Proteomic-based prognosis of brain tumor patients using direct-tissue matrix-assisted laser desorption ionization mass spectrometry. Cancer Res. 2005 Sep 1;65(17):7674-81.