Robert Anthony Bambara, Ph.D.

Robert Anthony Bambara, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 672
Rochester, NY 14642

Office: (585) 275-2764
Fax: (585) 275-6007

Journal Articles

Showing all 245 journal articles available.

2014 Jun 13
Amie SM, Daly MB, Noble E, Schinazi RF, Bambara RA, Kim B. "Anti-HIV host factor SAMHD1 regulates viral sensitivity to nucleoside reverse transcriptase inhibitors via modulation of cellular deoxyribonucleoside triphosphate (dNTP) levels." The Journal of biological chemistry.. 2014 Jun 13; 289(24):16640.
2014 Jun 13
Amie SM, Bambara RA, Kim B. "GTP is the primary activator of the anti-HIV restriction factor SAMHD1." The Journal of biological chemistry.. 2014 Jun 13; 289(24):16641.
2014 Apr 29
Piekna-Przybylska D, Sullivan MA, Sharma G, Bambara RA. "U3 region in the HIV-1 genome adopts a G-quadruplex structure in its RNA and DNA sequence." Biochemistry.. 2014 Apr 29; 53(16):2581-93. Epub 2014 Apr 15.
2013 Oct
Wang J, Li D, Bambara RA, Dykes C. "Reverse transcriptase backbone can alter the polymerization and RNase activities of non-nucleoside reverse transcriptase mutants K101E+G190S." The Journal of general virology. 2013 Oct; 94(Pt 10):2297-308. Epub 2013 Jun 26.
2013 Aug 30
Amie SM, Bambara RA, Kim B. "GTP is the primary activator of the anti-HIV restriction factor SAMHD1." The Journal of biological chemistry.. 2013 Aug 30; 288(35):25001-6. Epub 2013 Jul 23.
2013 Jul 23
Muchiri JM, Li D, Dykes C, Bambara RA. "Efavirenz stimulates HIV-1 reverse transcriptase RNase H activity by a mechanism involving increased substrate binding and secondary cleavage activity." Biochemistry.. 2013 Jul 23; 52(29):4981-90. Epub 2013 Jul 09.
2013 Jul
Wang J, Li D, Bambara RA, Yang H, Dykes C. "L74V increases the reverse transcriptase content of HIV-1 virions with non-nucleoside reverse transcriptase drug-resistant mutations L100I+K103N and K101E+G190S, which results in increased fitness." The Journal of general virology. 2013 Jul; 94(Pt 7):1597-607. Epub 2013 Mar 27.
2012 Aug 30
Kantartzis A, Williams GM, Balakrishnan L, Roberts RL, Surtees JA, Bambara RA. "Msh2-Msh3 interferes with Okazaki fragment processing to promote trinucleotide repeat expansions." Cell reports. 2012 Aug 30; 2(2):216-22. Epub 2012 Aug 02.
2012 Aug
Gloor JW, Balakrishnan L, Campbell JL, Bambara RA. "Biochemical analyses indicate that binding and cleavage specificities define the ordered processing of human Okazaki fragments by Dna2 and FEN1." Nucleic acids research.. 2012 Aug; 40(14):6774-86. Epub 2012 May 07.
2012 Apr 20
Kennedy EM, Amie SM, Bambara RA, Kim B. "Frequent incorporation of ribonucleotides during HIV-1 reverse transcription and their attenuated repair in macrophages." The Journal of biological chemistry.. 2012 Apr 20; 287(17):14280-8. Epub 2012 Mar 01.
2012 Mar 1
Miller A, Balakrishnan L, Buncher NA, Opresko PL, Bambara RA. "Telomere proteins POT1, TRF1 and TRF2 augment long-patch base excision repair in vitro." Cell cycle.. 2012 Mar 1; 11(5):998-1007. Epub 2012 Mar 01.
2012 Jan 13
Nguyen LA, Daddacha W, Rigby S, Bambara RA, Kim B. "Altered strand transfer activity of a multiple-drug-resistant human immunodeficiency virus type 1 reverse transcriptase mutant with a dipeptide fingers domain insertion." Journal of molecular biology.. 2012 Jan 13; 415(2):248-62. Epub 2011 Nov 12.
2011 Oct
Wang J, Zhang G, Bambara RA, Li D, Liang H, Wu H, Smith HM, Lowe NR, Demeter LM, Dykes C. "Nonnucleoside reverse transcriptase inhibitor-resistant HIV is stimulated by efavirenz during early stages of infection." Journal of virology.. 2011 Oct; 85(20):10861-73. Epub 2011 Aug 10.
2011 Aug 26
Shen W, Gorelick RJ, Bambara RA. "HIV-1 nucleocapsid protein increases strand transfer recombination by promoting dimeric G-quartet formation." The Journal of biological chemistry.. 2011 Aug 26; 286(34):29838-47. Epub 2011 Jul 07.
2011 Aug 15
Balakrishnan L, Bambara RA. "The changing view of Dna2." Cell cycle.. 2011 Aug 15; 10(16):2620-1. Epub 2011 Aug 15.
2011 Aug 1
Gewandter JS, Bambara RA, O'Reilly MA. "The RNA surveillance protein SMG1 activates p53 in response to DNA double-strand breaks but not exogenously oxidized mRNA." Cell cycle.. 2011 Aug 1; 10(15):2561-7. Epub 2011 Aug 01.
2011 Jul 8
Fortini BK, Pokharel S, Polaczek P, Balakrishnan L, Bambara RA, Campbell JL. "Characterization of the endonuclease and ATP-dependent flap endo/exonuclease of Dna2." The Journal of biological chemistry.. 2011 Jul 8; 286(27):23763-70. Epub 2011 May 13.
2011 Feb 20
Piekna-Przybylska D, Dykes C, Demeter LM, Bambara RA. "Sequences in the U3 region of human immunodeficiency virus 1 improve efficiency of minus strand transfer in infected cells." Virology.. 2011 Feb 20; 410(2):368-74. Epub 2010 Dec 30.
2011
Piekna-Przybylska D, Bambara RA. "Requirements for efficient minus strand strong-stop DNA transfer in human immunodeficiency virus 1." RNA biology. 2011 8(2):230-6. Epub 2011 Mar 01.
2010 Nov 5
Gloor JW, Balakrishnan L, Bambara RA. "Flap endonuclease 1 mechanism analysis indicates flap base binding prior to threading." The Journal of biological chemistry.. 2010 Nov 5; 285(45):34922-31. Epub 2010 Aug 25.
2010 Sep 10
Henry RA, Balakrishnan L, Tan Ying-Lin S, Campbell JL, Bambara RA. "Components of the secondary pathway stimulate the primary pathway of eukaryotic Okazaki fragment processing." The Journal of biological chemistry.. 2010 Sep 10; 285(37):28496-505. Epub 2010 Jul 13.
2010 Sep
Wang J, Bambara RA, Dykes C. "Reduced fitness in cell culture of HIV-1 with nonnucleoside reverse transcriptase inhibitor-resistant mutations correlates with relative levels of reverse transcriptase content and RNase H activity in virions." Journal of virology.. 2010 Sep; 84(18):9377-89. Epub 2010 Jun 30.
2010 Jul
Balakrishnan L, Gloor JW, Bambara RA. "Reconstitution of eukaryotic lagging strand DNA replication." Methods (San Diego, Calif.). 2010 Jul; 51(3):347-57. Epub 2010 Feb 21.
2010 Feb 12
Balakrishnan L, Stewart J, Polaczek P, Campbell JL, Bambara RA. "Acetylation of Dna2 endonuclease/helicase and flap endonuclease 1 by p300 promotes DNA stability by creating long flap intermediates." The Journal of biological chemistry.. 2010 Feb 12; 285(7):4398-404. Epub 2009 Dec 17.
2010 Jan
Stewart JA, Campbell JL, Bambara RA. "Dna2 is a structure-specific nuclease, with affinity for 5'-flap intermediates." Nucleic acids research.. 2010 Jan; 38(3):920-30. Epub 2009 Nov 24.
2010 Jan
Piekna-Przybylska D, Dichiacchio L, Mathews DH, Bambara RA. "A sequence similar to tRNA 3 Lys gene is embedded in HIV-1 U3-R and promotes minus-strand transfer." Nature structural & molecular biology. 2010 Jan; 17(1):83-9. Epub 2009 Dec 06.
2010
Pike JE, Henry RA, Burgers PM, Campbell JL, Bambara RA. "An alternative pathway for Okazaki fragment processing: resolution of fold-back flaps by Pif1 helicase." The Journal of biological chemistry.. 2010 285(53):41712-23. Epub 2010 Oct 19.
2010
Balakrishnan L, Polaczek P, Pokharel S, Campbell JL, Bambara RA. "Dna2 exhibits a unique strand end-dependent helicase function." The Journal of biological chemistry.. 2010 285(50):38861-8. Epub 2010 Oct 06.
2009 Sep 11
Pike JE, Burgers PM, Campbell JL, Bambara RA. "Pif1 helicase lengthens some Okazaki fragment flaps necessitating Dna2 nuclease/helicase action in the two-nuclease processing pathway." The Journal of biological chemistry.. 2009 Sep 11; 284(37):25170-80. Epub 2009 Jul 15.
2009 May 29
Balakrishnan L, Brandt PD, Lindsey-Boltz LA, Sancar A, Bambara RA. "Long patch base excision repair proceeds via coordinated stimulation of the multienzyme DNA repair complex." The Journal of biological chemistry.. 2009 May 29; 284(22):15158-72. Epub 2009 Mar 27.
2009 Apr 24
Rigby ST, Rose AE, Hanson MN, Bambara RA. "Mechanism analysis indicates that recombination events in HIV-1 initiate and complete over short distances, explaining why recombination frequencies are similar in different sections of the genome." Journal of molecular biology.. 2009 Apr 24; 388(1):30-47. Epub 2009 Feb 20.
2009 Mar 27
Stewart JA, Campbell JL, Bambara RA. "Significance of the dissociation of Dna2 by flap endonuclease 1 to Okazaki fragment processing in Saccharomyces cerevisiae." The Journal of biological chemistry.. 2009 Mar 27; 284(13):8283-91. Epub 2009 Jan 29.
2009 Mar 3
Song M, Balakrishnan M, Gorelick RJ, Bambara RA. "A succession of mechanisms stimulate efficient reconstituted HIV-1 minus strand strong stop DNA transfer." Biochemistry.. 2009 Mar 3; 48(8):1810-9.
2009
Rigby ST, Van Nostrand KP, Rose AE, Gorelick RJ, Mathews DH, Bambara RA. "Factors that determine the efficiency of HIV-1 strand transfer initiated at a specific site." Journal of molecular biology.. 2009 394(4):694-707. Epub 2009 Oct 21.
2009
Shen W, Gao L, Balakrishnan M, Bambara RA. "A recombination hot spot in HIV-1 contains guanosine runs that can form a G-quartet structure and promote strand transfer in vitro." The Journal of biological chemistry.. 2009 284(49):33883-93. Epub 2009 Oct 12.
2008 Nov 14
Stewart JA, Miller AS, Campbell JL, Bambara RA. "Dynamic removal of replication protein A by Dna2 facilitates primer cleavage during Okazaki fragment processing in Saccharomyces cerevisiae." The Journal of biological chemistry.. 2008 Nov 14; 283(46):31356-65. Epub 2008 Sep 17.
2008 Oct 10
Rossi ML, Pike JE, Wang W, Burgers PM, Campbell JL, Bambara RA. "Pif1 helicase directs eukaryotic Okazaki fragments toward the two-nuclease cleavage pathway for primer removal." The Journal of biological chemistry.. 2008 Oct 10; 283(41):27483-93. Epub 2008 Aug 09.
2008 Aug 1
Bartos JD, Willmott LJ, Binz SK, Wold MS, Bambara RA. "Catalysis of strand annealing by replication protein A derives from its strand melting properties." The Journal of biological chemistry.. 2008 Aug 1; 283(31):21758-68. Epub 2008 Jun 03.
2008 Jul 3
Gehen SC, Staversky RJ, Bambara RA, Keng PC, O'Reilly MA. "hSMG-1 and ATM sequentially and independently regulate the G1 checkpoint during oxidative stress." Oncogene.. 2008 Jul 3; 27(29):4065-74. Epub 2008 Mar 10.
2008 Jun
Basu VP, Song M, Gao L, Rigby ST, Hanson MN, Bambara RA. "Strand transfer events during HIV-1 reverse transcription." Virus research. 2008 Jun; 134(1-2):19-38. Epub 2008 Feb 14.
2008 May
Li X, Nott SL, Huang Y, Hilf R, Bambara RA, Qiu X, Yakovlev A, Welle S, Muyan M. "Gene expression profiling reveals that the regulation of estrogen-responsive element-independent genes by 17 beta-estradiol-estrogen receptor beta is uncoupled from the induction of phenotypic changes in cell models." Journal of molecular endocrinology.. 2008 May; 40(5):211-29.
2008 Apr 4
Jamburuthugoda VK, Santos-Velazquez JM, Skasko M, Operario DJ, Purohit V, Chugh P, Szymanski EA, Wedekind JE, Bambara RA, Kim B. "Reduced dNTP binding affinity of 3TC-resistant M184I HIV-1 reverse transcriptase variants responsible for viral infection failure in macrophage." The Journal of biological chemistry.. 2008 Apr 4; 283(14):9206-16. Epub 2008 Jan 24.
2008 Apr 4
Gao L, Hanson MN, Balakrishnan M, Boyer PL, Roques BP, Hughes SH, Kim B, Bambara RA. "Apparent defects in processive DNA synthesis, strand transfer, and primer elongation of Met-184 mutants of HIV-1 reverse transcriptase derive solely from a dNTP utilization defect." The Journal of biological chemistry.. 2008 Apr 4; 283(14):9196-205. Epub 2008 Jan 24.
2008 Feb 8
Song M, Basu VP, Hanson MN, Roques BP, Bambara RA. "Proximity and branch migration mechanisms in HIV-1 minus strand strong stop DNA transfer." The Journal of biological chemistry.. 2008 Feb 8; 283(6):3141-50. Epub 2007 Dec 11.
2007 Apr 27
Purohit V, Roques BP, Kim B, Bambara RA. "Mechanisms that prevent template inactivation by HIV-1 reverse transcriptase RNase H cleavages." The Journal of biological chemistry.. 2007 Apr 27; 282(17):12598-609. Epub 2007 Mar 02.
2007 Mar 2
Gao L, Balakrishnan M, Roques BP, Bambara RA. "Insights into the multiple roles of pausing in HIV-1 reverse transcriptase-promoted strand transfers." The Journal of biological chemistry.. 2007 Mar 2; 282(9):6222-31. Epub 2007 Jan 03.
2007 Mar
Gehen SC, Vitiello PF, Bambara RA, Keng PC, O'Reilly MA. "Downregulation of PCNA potentiates p21-mediated growth inhibition in response to hyperoxia." American journal of physiology. Lung cellular and molecular physiology.. 2007 Mar; 292(3):L716-24. Epub 2006 Nov 03.
2006 Nov 10
Hanson MN, Balakrishnan M, Roques BP, Bambara RA. "Evidence that creation of invasion sites determines the rate of strand transfer mediated by HIV-1 reverse transcriptase." Journal of molecular biology.. 2006 Nov 10; 363(5):878-90. Epub 2006 Aug 30.
2006 Oct 27
Operario DJ, Balakrishnan M, Bambara RA, Kim B. "Reduced dNTP interaction of human immunodeficiency virus type 1 reverse transcriptase promotes strand transfer." The Journal of biological chemistry.. 2006 Oct 27; 281(43):32113-21. Epub 2006 Aug 21.
2006 Oct 27
Bartos JD, Wang W, Pike JE, Bambara RA. "Mechanisms by which Bloom protein can disrupt recombination intermediates of Okazaki fragment maturation." The Journal of biological chemistry.. 2006 Oct 27; 281(43):32227-39. Epub 2006 Aug 31.
2006 Sep 8
Rossi ML, Bambara RA. "Reconstituted Okazaki fragment processing indicates two pathways of primer removal." The Journal of biological chemistry.. 2006 Sep 8; 281(36):26051-61. Epub 2006 Jul 11.
2006 Aug 25
Song M, Balakrishnan M, Chen Y, Roques BP, Bambara RA. "Stimulation of HIV-1 minus strand strong stop DNA transfer by genomic sequences 3' of the primer binding site." The Journal of biological chemistry.. 2006 Aug 25; 281(34):24227-35. Epub 2006 Jun 15.
2006 Aug 18
Brandt PD, Helt CE, Keng PC, Bambara RA. "The Rad9 protein enhances survival and promotes DNA repair following exposure to ionizing radiation." Biochemical and biophysical research communications.. 2006 Aug 18; 347(1):232-7. Epub 2006 Jun 21.
2006 Aug 1
Domaoal RA, Bambara RA, Demeter LM. "HIV-1 reverse transcriptase mutants resistant to nonnucleoside reverse transcriptase inhibitors do not adversely affect DNA synthesis: pre-steady-state and steady-state kinetic studies." Journal of acquired immune deficiency syndromes : JAIDS.. 2006 Aug 1; 42(4):405-11.
2006 Jul 28
Wang W, Lindsey-Boltz LA, Sancar A, Bambara RA. "Mechanism of stimulation of human DNA ligase I by the Rad9-rad1-Hus1 checkpoint complex." The Journal of biological chemistry.. 2006 Jul 28; 281(30):20865-72. Epub 2006 May 25.
2006 May 10
Wang J, Dykes C, Domaoal RA, Koval CE, Bambara RA, Demeter LM. "The HIV-1 reverse transcriptase mutants G190S and G190A, which confer resistance to non-nucleoside reverse transcriptase inhibitors, demonstrate reductions in RNase H activity and DNA synthesis from tRNA(Lys, 3) that correlate with reductions in replication efficiency." Virology.. 2006 May 10; 348(2):462-74. Epub 2006 Feb 28.
2006 Feb
Rossi ML, Purohit V, Brandt PD, Bambara RA. "Lagging strand replication proteins in genome stability and DNA repair." Chemical reviews. 2006 Feb; 106(2):453-73.
2006
Stewart JA, Campbell JL, Bambara RA. "Flap endonuclease disengages Dna2 helicase/nuclease from Okazaki fragment flaps." The Journal of biological chemistry.. 2006 281(50):38565-72. Epub 2006 Oct 11.
2006
Huang J, Li X, Qiao T, Bambara RA, Hilf R, Muyan M. "A tale of two estrogen receptors (ERs): how differential ER-estrogen responsive element interactions contribute to subtype-specific transcriptional responses." Nuclear receptor signaling. 2006 4:e015. Epub 2006 Jul 07.
2005 Nov 4
Hanson MN, Balakrishnan M, Roques BP, Bambara RA. "Effects of donor and acceptor RNA structures on the mechanism of strand transfer by HIV-1 reverse transcriptase." Journal of molecular biology.. 2005 Nov 4; 353(4):772-87. Epub 2005 Sep 26.
2005 Nov
Huang J, Li X, Maguire CA, Hilf R, Bambara RA, Muyan M. "Binding of estrogen receptor beta to estrogen response element in situ is independent of estradiol and impaired by its amino terminus." Molecular endocrinology.. 2005 Nov; 19(11):2696-712. Epub 2005 Jun 23.
2005 Apr 15
Chen Y, Balakrishnan M, Roques BP, Bambara RA. "Acceptor RNA cleavage profile supports an invasion mechanism for HIV-1 minus strand transfer." The Journal of biological chemistry.. 2005 Apr 15; 280(15):14443-52. Epub 2005 Jan 18.
2005 Apr
Helt CE, Wang W, Keng PC, Bambara RA. "Evidence that DNA damage detection machinery participates in DNA repair." Cell cycle.. 2005 Apr; 4(4):529-32. Epub 2005 Apr 10.
2005 Feb 18
Wang W, Bambara RA. "Human Bloom protein stimulates flap endonuclease 1 activity by resolving DNA secondary structure." The Journal of biological chemistry.. 2005 Feb 18; 280(7):5391-9. Epub 2004 Dec 04.
2005 Jan 14
Helt CE, Cliby WA, Keng PC, Bambara RA, O'Reilly MA. "Ataxia telangiectasia mutated (ATM) and ATM and Rad3-related protein exhibit selective target specificities in response to different forms of DNA damage." The Journal of biological chemistry.. 2005 Jan 14; 280(2):1186-92. Epub 2004 Nov 08.
2005
Purohit V, Balakrishnan M, Kim B, Bambara RA. "Evidence that HIV-1 reverse transcriptase employs the DNA 3' end-directed primary/secondary RNase H cleavage mechanism during synthesis and strand transfer." The Journal of biological chemistry.. 2005 280(49):40534-43. Epub 2005 Oct 11.
2005
Huang J, Li X, Hilf R, Bambara RA, Muyan M. "Molecular basis of therapeutic strategies for breast cancer." Current drug targets. Immune, endocrine and metabolic disorders. 2005 5(4):379-96.
2004 Nov 30
Wang W, Brandt P, Rossi ML, Lindsey-Boltz L, Podust V, Fanning E, Sancar A, Bambara RA. "The human Rad9-Rad1-Hus1 checkpoint complex stimulates flap endonuclease 1." Proceedings of the National Academy of Sciences of the United States of America.. 2004 Nov 30; 101(48):16762-7. Epub 2004 Nov 19.
2004 Sep 1
Dykes C, Balakrishnan M, Planelles V, Zhu Y, Bambara RA, Demeter LM. "Identification of a preferred region for recombination and mutation in HIV-1 gag." Virology.. 2004 Sep 1; 326(2):262-79.
2004 Sep
Li X, Huang J, Yi P, Bambara RA, Hilf R, Muyan M. "Single-chain estrogen receptors (ERs) reveal that the ERalpha/beta heterodimer emulates functions of the ERalpha dimer in genomic estrogen signaling pathways." Molecular and cellular biology.. 2004 Sep; 24(17):7681-94.
2004 May
Liu Y, Zhang H, Veeraraghavan J, Bambara RA, Freudenreich CH. "Saccharomyces cerevisiae flap endonuclease 1 uses flap equilibration to maintain triplet repeat stability." Molecular and cellular biology.. 2004 May; 24(9):4049-64.
2004 Apr 20
Weiss KK, Chen R, Skasko M, Reynolds HM, Lee K, Bambara RA, Mansky LM, Kim B. "A role for dNTP binding of human immunodeficiency virus type 1 reverse transcriptase in viral mutagenesis." Biochemistry.. 2004 Apr 20; 43(15):4490-500.
2004 Apr 15
Huang J, Li X, Yi P, Hilf R, Bambara RA, Muyan M. "Targeting estrogen responsive elements (EREs): design of potent transactivators for ERE-containing genes." Molecular and cellular endocrinology.. 2004 Apr 15; 218(1-2):65-78.
2004 Apr 9
Kao HI, Veeraraghavan J, Polaczek P, Campbell JL, Bambara RA. "On the roles of Saccharomyces cerevisiae Dna2p and Flap endonuclease 1 in Okazaki fragment processing." The Journal of biological chemistry.. 2004 Apr 9; 279(15):15014-24. Epub 2004 Jan 26.
2004 Mar
Helt CE, Staversky RJ, Lee YJ, Bambara RA, Keng PC, O'Reilly MA. "The Cdk and PCNA domains on p21Cip1 both function to inhibit G1/S progression during hyperoxia." American journal of physiology. Lung cellular and molecular physiology.. 2004 Mar; 286(3):L506-13. Epub 2003 Aug 22.
2004 Feb
Sharma S, Otterlei M, Sommers JA, Driscoll HC, Dianov GL, Kao HI, Bambara RA, Brosh RM. "WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork." Molecular biology of the cell.. 2004 Feb; 15(2):734-50. Epub 2003 Dec 02.
2004
Kao HI, Campbell JL, Bambara RA. "Dna2p helicase/nuclease is a tracking protein, like FEN1, for flap cleavage during Okazaki fragment maturation." The Journal of biological chemistry.. 2004 279(49):50840-9. Epub 2004 Sep 22.
2004
Diamond TL, Roshal M, Jamburuthugoda VK, Reynolds HM, Merriam AR, Lee KY, Balakrishnan M, Bambara RA, Planelles V, Dewhurst S, Kim B. "Macrophage tropism of HIV-1 depends on efficient cellular dNTP utilization by reverse transcriptase." The Journal of biological chemistry.. 2004 279(49):51545-53. Epub 2004 Sep 26.
2004
Renda, M. J.; Bradel-Tretheway, B.; Planelles, V.; Bambara, R. A.; Dewhurst, S.;. "Inhibition of HIV Type1 Replication Using Lentiviral-Mediated Delivery of Mutant tRNA(Lys3)A58U". AIDS Res. & Human Retroviruses. 2004; 20(3): 1324-1334.
2004
Liu Y, Kao HI, Bambara RA. "Flap endonuclease 1: a central component of DNA metabolism." Annual review of biochemistry.. 2004 73:589-615.
2004
Renda MJ, Bradel-Tretheway B, Planelles V, Bambara RA, Dewhurst S. "Inhibition of HIV type 1 replication using lentiviral-mediated delivery of mutant tRNA(Lys3)A58U." AIDS research and human retroviruses.. 2004 20(12):1324-34.
2003 Oct 31
Veeraraghavan J, Rossi ML, Bambara RA. "Analysis of DNA replication intermediates suggests mechanisms of repeat sequence expansion." The Journal of biological chemistry.. 2003 Oct 31; 278(44):42854-66. Epub 2003 Aug 05.
2003 Oct 3
Chen Y, Balakrishnan M, Roques BP, Bambara RA. "Steps of the acceptor invasion mechanism for HIV-1 minus strand strong stop transfer." The Journal of biological chemistry.. 2003 Oct 3; 278(40):38368-75. Epub 2003 Jul 22.
2003 Aug 22
Roda RH, Balakrishnan M, Hanson MN, Wohrl BM, Le Grice SF, Roques BP, Gorelick RJ, Bambara RA. "Role of the Reverse Transcriptase, Nucleocapsid Protein, and Template Structure in the Two-step Transfer Mechanism in Retroviral Recombination." The Journal of biological chemistry.. 2003 Aug 22; 278(34):31536-46. Epub 2003 Jun 11.
2003 Aug 8
Diamond TL, Souroullas G, Weiss KK, Lee KY, Bambara RA, Dewhurst S, Kim B. "Mechanistic understanding of an altered fidelity simian immunodeficiency virus reverse transcriptase mutation, V148I, identified in a pig-tailed macaque." The Journal of biological chemistry.. 2003 Aug 8; 278(32):29913-24. Epub 2003 May 08.
2003 Apr 18
Liu Y, Bambara RA. "Analysis of human flap endonuclease 1 mutants reveals a mechanism to prevent triplet repeat expansion." The Journal of biological chemistry.. 2003 Apr 18; 278(16):13728-39. Epub 2003 Jan 28.
2003 Apr
Balakrishnan M, Roques BP, Fay PJ, Bambara RA. "Template dimerization promotes an acceptor invasion-induced transfer mechanism during human immunodeficiency virus type 1 minus-strand synthesis." Journal of virology.. 2003 Apr; 77(8):4710-21.
2003 Mar 7
Chen Y, Balakrishnan M, Roques BP, Fay PJ, Bambara RA. "Mechanism of minus strand strong stop transfer in HIV-1 reverse transcription." The Journal of biological chemistry.. 2003 Mar 7; 278(10):8006-17. Epub 2002 Dec 23.
2003
Kao HI, Bambara RA. "The protein components and mechanism of eukaryotic Okazaki fragment maturation." Critical reviews in biochemistry and molecular biology. 2003 38(5):433-52.
2002 Nov 1
Ranalli TA, Tom S, Bambara RA. "AP endonuclease 1 coordinates flap endonuclease 1 and DNA ligase I activity in long patch base excision repair." The Journal of biological chemistry.. 2002 Nov 1; 277(44):41715-24. Epub 2002 Aug 27.
2002 Nov
Huggins CF, Chafin DR, Aoyagi S, Henricksen LA, Bambara RA, Hayes JJ. "Flap endonuclease 1 efficiently cleaves base excision repair and DNA replication intermediates assembled into nucleosomes." Molecular cell. 2002 Nov; 10(5):1201-11.
2002 Aug 9
Wisniewski M, Chen Y, Balakrishnan M, Palaniappan C, Roques BP, Fay PJ, Bambara RA. "Substrate requirements for secondary cleavage by HIV-1 reverse transcriptase RNase H." The Journal of biological chemistry.. 2002 Aug 9; 277(32):28400-10. Epub 2002 May 21.
2002 Aug
Yi P, Bhagat S, Hilf R, Bambara RA, Muyan M. "Differences in the abilities of estrogen receptors to integrate activation functions are critical for subtype-specific transcriptional responses." Molecular endocrinology.. 2002 Aug; 16(8):1810-27.
2002 Jun 28
Sathya G, Yi P, Bhagat S, Bambara RA, Hilf R, Muyan M. "Structural regions of ERalpha critical for synergistic transcriptional responses contain co-factor interacting surfaces." Molecular and cellular endocrinology.. 2002 Jun 28; 192(1-2):171-85.
2002 Jun 21
Weiss KK, Bambara RA, Kim B. "Mechanistic role of residue Gln151 in error prone DNA synthesis by human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT). Pre-steady state kinetic study of the Q151N HIV-1 RT mutant with increased fidelity." The Journal of biological chemistry.. 2002 Jun 21; 277(25):22662-9. Epub 2002 Apr 01.
2002 Jun 21
Henricksen LA, Veeraraghavan J, Chafin DR, Bambara RA. "DNA ligase I competes with FEN1 to expand repetitive DNA sequences in vitro." The Journal of biological chemistry.. 2002 Jun 21; 277(25):22361-9. Epub 2002 Apr 10.
2002 Apr 26
Kao HI, Henricksen LA, Liu Y, Bambara RA. "Cleavage specificity of Saccharomyces cerevisiae flap endonuclease 1 suggests a double-flap structure as the cellular substrate." The Journal of biological chemistry.. 2002 Apr 26; 277(17):14379-89. Epub 2002 Feb 01.
2002 Apr
Yi P, Driscoll MD, Huang J, Bhagat S, Hilf R, Bambara RA, Muyan M. "The effects of estrogen-responsive element- and ligand-induced structural changes on the recruitment of cofactors and transcriptional responses by ER alpha and ER beta." Molecular endocrinology.. 2002 Apr; 16(4):674-93.
2002 Jan 18
Ranalli TA, DeMott MS, Bambara RA. "Mechanism underlying replication protein a stimulation of DNA ligase I." The Journal of biological chemistry.. 2002 Jan 18; 277(3):1719-27. Epub 2001 Nov 06.
2002
Roda RH, Balakrishnan M, Kim JK, Roques BP, Fay PJ, Bambara RA. "Strand transfer occurs in retroviruses by a pause-initiated two-step mechanism." The Journal of biological chemistry.. 2002 277(49):46900-11. Epub 2002 Oct 04.
2002
Kao, H.I.; Bambara, R.A.;. "RPA Governs Endonuclease Switching During Processing of Okazaki Fragments in Eukaryotes". Chemtracts - Biochemistry & Molecular Biology, Eukaryotic DNA Replication. 2002; : 326-333. Link
2001 Oct
Renda MJ, Rosenblatt JD, Klimatcheva E, Demeter LM, Bambara RA, Planelles V. "Mutation of the methylated tRNA(Lys)(3) residue A58 disrupts reverse transcription and inhibits replication of human immunodeficiency virus type 1." Journal of virology.. 2001 Oct; 75(20):9671-8.
2001 Sep 28
Balakrishnan M, Fay PJ, Bambara RA. "The kissing hairpin sequence promotes recombination within the HIV-I 5' leader region." The Journal of biological chemistry.. 2001 Sep 28; 276(39):36482-92. Epub 2001 Jun 29.
2001 Sep
Muyan M, Yi P, Sathya G, Willmert LJ, Driscoll MD, Hilf R, Bambara RA. "Fusion estrogen receptor proteins: toward the development of receptor-based agonists and antagonists." Molecular and cellular endocrinology.. 2001 Sep; 182(2):249-63.
2001 Aug
Xie Y, Liu Y, Argueso JL, Henricksen LA, Kao HI, Bambara RA, Alani E. "Identification of rad27 mutations that confer differential defects in mutation avoidance, repeat tract instability, and flap cleavage." Molecular and cellular biology.. 2001 Aug; 21(15):4889-99.
2001 Jul 6
Tom S, Henricksen LA, Park MS, Bambara RA. "DNA ligase I and proliferating cell nuclear antigen form a functional complex." The Journal of biological chemistry.. 2001 Jul 6; 276(27):24817-25. Epub 2001 Apr 30.
2001 Apr 3
Archer RH, Wisniewski M, Bambara RA, Demeter LM. "The Y181C mutant of HIV-1 reverse transcriptase resistant to nonnucleoside reverse transcriptase inhibitors alters the size distribution of RNase H cleavages." Biochemistry.. 2001 Apr 3; 40(13):4087-95.
2001
Tom S, Ranalli TA, Podust VN, Bambara RA. "Regulatory roles of p21 and apurinic/apyrimidinic endonuclease 1 in base excision repair." The Journal of biological chemistry.. 2001 276(52):48781-9. Epub 2001 Oct 18.
2000 Oct 24
Wisniewski M, Balakrishnan M, Palaniappan C, Fay PJ, Bambara RA. "Unique progressive cleavage mechanism of HIV reverse transcriptase RNase H." Proceedings of the National Academy of Sciences of the United States of America.. 2000 Oct 24; 97(22):11978-83.
2000 Oct 16
Chafin DR, Vitolo JM, Henricksen LA, Bambara RA, Hayes JJ. "Human DNA ligase I efficiently seals nicks in nucleosomes." The EMBO journal. 2000 Oct 16; 19(20):5492-501.
2000 Sep
Archer RH, Dykes C, Gerondelis P, Lloyd A, Fay P, Reichman RC, Bambara RA, Demeter LM. "Mutants of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase resistant to nonnucleoside reverse transcriptase inhibitors demonstrate altered rates of RNase H cleavage that correlate with HIV-1 replication fitness in cell culture." Journal of virology.. 2000 Sep; 74(18):8390-401.
2000 Jun 2
Henricksen LA, Tom S, Liu Y, Bambara RA. "Inhibition of flap endonuclease 1 by flap secondary structure and relevance to repeat sequence expansion." The Journal of biological chemistry.. 2000 Jun 2; 275(22):16420-7.
2000 Apr 7
Tom S, Henricksen LA, Bambara RA. "Mechanism whereby proliferating cell nuclear antigen stimulates flap endonuclease 1." The Journal of biological chemistry.. 2000 Apr 7; 275(14):10498-505.
2000
Wisniewski M, Balakrishnan M, Palaniappan C, Fay PJ, Bambara RA. "The sequential mechanism of HIV reverse transcriptase RNase H." The Journal of biological chemistry.. 2000 275(48):37664-71.
1999 Oct 5
Bornarth CJ, Ranalli TA, Henricksen LA, Wahl AF, Bambara RA. "Effect of flap modifications on human FEN1 cleavage." Biochemistry.. 1999 Oct 5; 38(40):13347-54.
1999 Oct 1
Wisniewski M, Palaniappan C, Fu Z, Le Grice SF, Fay P, Bambara RA. "Mutations in the primer grip region of HIV reverse transcriptase can increase replication fidelity." The Journal of biological chemistry.. 1999 Oct 1; 274(40):28175-84.
1999 Jul
Gerondelis P, Archer RH, Palaniappan C, Reichman RC, Fay PJ, Bambara RA, Demeter LM. "The P236L delavirdine-resistant human immunodeficiency virus type 1 mutant is replication defective and demonstrates alterations in both RNA 5'-end- and DNA 3'-end-directed RNase H activities." Journal of virology.. 1999 Jul; 73(7):5803-13.
1999 Jun
Driscoll MD, Sathya G, Saidi LF, DeMott MS, Hilf R, Bambara RA. "An explanation for observed estrogen receptor binding to single-stranded estrogen-responsive element DNA." Molecular endocrinology.. 1999 Jun; 13(6):958-68.
1999 May 21
Rumbaugh JA, Henricksen LA, DeMott MS, Bambara RA. "Cleavage of substrates with mismatched nucleotides by Flap endonuclease-1. Implications for mammalian Okazaki fragment processing." The Journal of biological chemistry.. 1999 May 21; 274(21):14602-8.
1998 Nov 6
Driscoll MD, Sathya G, Muyan M, Klinge CM, Hilf R, Bambara RA. "Sequence requirements for estrogen receptor binding to estrogen response elements." The Journal of biological chemistry.. 1998 Nov 6; 273(45):29321-30.
1998 Oct 30
Rumbaugh JA, Fuentes GM, Bambara RA. "Processing of an HIV replication intermediate by the human DNA replication enzyme FEN1." The Journal of biological chemistry.. 1998 Oct 30; 273(44):28740-5.
1998 Oct 16
DeMott MS, Zigman S, Bambara RA. "Replication protein A stimulates long patch DNA base excision repair." The Journal of biological chemistry.. 1998 Oct 16; 273(42):27492-8.
1998 Aug 25
Klinge CM, Studinski-Jones AL, Kulakosky PC, Bambara RA, Hilf R. "Comparison of tamoxifen ligands on estrogen receptor interaction with estrogen response elements." Molecular and cellular endocrinology.. 1998 Aug 25; 143(1-2):79-90.
1998 Mar 3
Murante RS, Henricksen LA, Bambara RA. "Junction ribonuclease: an activity in Okazaki fragment processing." Proceedings of the National Academy of Sciences of the United States of America.. 1998 Mar 3; 95(5):2244-9.
1998 Feb 13
Palaniappan C, Kim JK, Wisniewski M, Fay PJ, Bambara RA. "Control of initiation of viral plus strand DNA synthesis by HIV reverse transcriptase." The Journal of biological chemistry.. 1998 Feb 13; 273(7):3808-16.
1998 Jan
Henricksen LA, Bambara RA. "Multiprotein reactions in mammalian DNA replication." Leukemia research.. 1998 Jan; 22(1):1-5.
1997 Sep 5
Rumbaugh JA, Murante RS, Shi S, Bambara RA. "Creation and removal of embedded ribonucleotides in chromosomal DNA during mammalian Okazaki fragment processing." The Journal of biological chemistry.. 1997 Sep 5; 272(36):22591-9.
1997 Jul 4
Kim JK, Palaniappan C, Wu W, Fay PJ, Bambara RA. "Evidence for a unique mechanism of strand transfer from the transactivation response region of HIV-1." The Journal of biological chemistry.. 1997 Jul 4; 272(27):16769-77.
1997 Jun 6
Lu Y, Planelles V, Li X, Palaniappan C, Day B, Challita-Eid P, Amado R, Stephens D, Kohn DB, Bakker A, Fay P, Bambara RA, Rosenblatt JD. "Inhibition of HIV-1 replication using a mutated tRNALys-3 primer." The Journal of biological chemistry.. 1997 Jun 6; 272(23):14523-31.
1997 Apr 25
Palaniappan C, Wisniewski M, Jacques PS, Le Grice SF, Fay PJ, Bambara RA. "Mutations within the primer grip region of HIV-1 reverse transcriptase result in loss of RNase H function." The Journal of biological chemistry.. 1997 Apr 25; 272(17):11157-64.
1997 Feb 21
Bambara RA, Murante RS, Henricksen LA. "Enzymes and reactions at the eukaryotic DNA replication fork." The Journal of biological chemistry.. 1997 Feb 21; 272(8):4647-50.
1997
Klinge CM, Silver BF, Driscoll MD, Sathya G, Bambara RA, Hilf R. "Chicken ovalbumin upstream promoter-transcription factor interacts with estrogen receptor, binds to estrogen response elements and half-sites, and inhibits estrogen-induced gene expression." The Journal of biological chemistry.. 1997 272(50):31465-74.
1997
Sathya G, Li W, Klinge CM, Anolik JH, Hilf R, Bambara RA. "Effects of multiple estrogen responsive elements, their spacing, and location on estrogen response of reporter genes." Molecular endocrinology.. 1997 11(13):1994-2003.
1997
Klinge CM, Brolly CL, Bambara RA, Hilf R. "hsp70 is not required for high affinity binding of purified calf uterine estrogen receptor to estrogen response element DNA in vitro." The Journal of steroid biochemistry and molecular biology.. 1997 63(4-6):283-301.
1996 Nov 22
Fuentes GM, Palaniappan C, Fay PJ, Bambara RA. "Strand displacement synthesis in the central polypurine tract region of HIV-1 promotes DNA to DNA strand transfer recombination." The Journal of biological chemistry.. 1996 Nov 22; 271(47):29605-11.
1996 Nov 22
Barnes CJ, Wahl AF, Shen B, Park MS, Bambara RA. "Mechanism of tracking and cleavage of adduct-damaged DNA substrates by the mammalian 5'- to 3'-exonuclease/endonuclease RAD2 homologue 1 or flap endonuclease 1." The Journal of biological chemistry.. 1996 Nov 22; 271(47):29624-31.
1996 Nov 22
DeMott MS, Shen B, Park MS, Bambara RA, Zigman S. "Human RAD2 homolog 1 5'- to 3'-exo/endonuclease can efficiently excise a displaced DNA fragment containing a 5'-terminal abasic lesion by endonuclease activity." The Journal of biological chemistry.. 1996 Nov 22; 271(47):30068-76.
1996 Oct 18
Murante RS, Rumbaugh JA, Barnes CJ, Norton JR, Bambara RA. "Calf RTH-1 nuclease can remove the initiator RNAs of Okazaki fragments by endonuclease activity." The Journal of biological chemistry.. 1996 Oct 18; 271(42):25888-97.
1996 Sep 13
Palaniappan C, Wisniewski M, Wu W, Fay PJ, Bambara RA. "Misincorporation by HIV-1 reverse transcriptase promotes recombination via strand transfer synthesis." The Journal of biological chemistry.. 1996 Sep 13; 271(37):22331-8.
1996 Jul 16
Huang L, Rumbaugh JA, Murante RS, Lin RJ, Rust L, Bambara RA. "Role of calf RTH-1 nuclease in removal of 5'-ribonucleotides during Okazaki fragment processing." Biochemistry.. 1996 Jul 16; 35(28):9266-77.
1996 May 1
Wu W, Palaniappan C, Bambara RA, Fay PJ. "Differences in mutagenesis during minus strand, plus strand and strand transfer (recombination) synthesis of the HIV-1 gene in vitro." Nucleic acids research.. 1996 May 1; 24(9):1710-8.
1996 May 1
Fuentes GM, Fay PJ, Bambara RA. "Relationship between plus strand DNA synthesis removal of downstream segments of RNA by human immunodeficiency virus, murine leukemia virus and avian myeloblastoma virus reverse transcriptases." Nucleic acids research.. 1996 May 1; 24(9):1719-26.
1996 May
Klinge CM, Traish AM, Driscoll MD, Hilf R, Bambara RA. "Site-directed estrogen receptor antibodies stabilize 4-hydroxytamoxifen ligand, but not estradiol, and indicate ligand-specific differences in the recognition of estrogen response element DNA in vitro." Steroids. 1996 May; 61(5):278-89.
1996 Apr
Driscoll MD, Klinge CM, Hilf R, Bambara RA. "Footprint analysis of estrogen receptor binding to adjacent estrogen response elements." The Journal of steroid biochemistry and molecular biology.. 1996 Apr; 58(1):45-61.
1996 Jan 26
Fuentes GM, Rodríguez-Rodríguez L, Palaniappan C, Fay PJ, Bambara RA. "Strand displacement synthesis of the long terminal repeats by HIV reverse transcriptase." The Journal of biological chemistry.. 1996 Jan 26; 271(4):1966-71.
1996 Jan 26
Palaniappan C, Fuentes GM, Rodríguez-Rodríguez L, Fay PJ, Bambara RA. "Helix structure and ends of RNA/DNA hybrids direct the cleavage specificity of HIV-1 reverse transcriptase RNase H." The Journal of biological chemistry.. 1996 Jan 26; 271(4):2063-70.
1996 Jan
Klinge CM, Traish AM, Bambara RA, Hilf R. "Dissociation of 4-hydroxytamoxifen, but not estradiol or tamoxifen aziridine, from the estrogen receptor as the receptor binds estrogen response element DNA." The Journal of steroid biochemistry and molecular biology.. 1996 Jan; 57(1-2):51-66.
1996
Anolik JH, Klinge CM, Brolly CL, Bambara RA, Hilf R. "Stability of the ligand-estrogen receptor interaction depends on estrogen response element flanking sequences and cellular factors." The Journal of steroid biochemistry and molecular biology.. 1996 59(5-6):413-29.
1995 Nov 24
Fuentes GM, Rodríguez-Rodríguez L, Fay PJ, Bambara RA. "Use of an oligoribonucleotide containing the polypurine tract sequence as a primer by HIV reverse transcriptase." The Journal of biological chemistry.. 1995 Nov 24; 270(47):28169-76.
1995 Jun 23
Rodríguez-Rodríguez L, Tsuchihashi Z, Fuentes GM, Bambara RA, Fay PJ. "Influence of human immunodeficiency virus nucleocapsid protein on synthesis and strand transfer by the reverse transcriptase in vitro." The Journal of biological chemistry.. 1995 Jun 23; 270(25):15005-11.
1995 Mar 3
Palaniappan C, Fay PJ, Bambara RA. "Nevirapine alters the cleavage specificity of ribonuclease H of human immunodeficiency virus 1 reverse transcriptase." The Journal of biological chemistry.. 1995 Mar 3; 270(9):4861-9.
1995 Feb 28
Anolik JH, Klinge CM, Hilf R, Bambara RA. "Cooperative binding of estrogen receptor to DNA depends on spacing of binding sites, flanking sequence, and ligand." Biochemistry.. 1995 Feb 28; 34(8):2511-20.
1995 Jan 6
Wu W, Blumberg BM, Fay PJ, Bambara RA. "Strand transfer mediated by human immunodeficiency virus reverse transcriptase in vitro is promoted by pausing and results in misincorporation." The Journal of biological chemistry.. 1995 Jan 6; 270(1):325-32.
1995
Murante RS, Rust L, Bambara RA. "Calf 5' to 3' exo/endonuclease must slide from a 5' end of the substrate to perform structure-specific cleavage." The Journal of biological chemistry.. 1995 270(51):30377-83.
1995
Bambara RA, Huang L. "Reconstitution of mammalian DNA replication." Progress in nucleic acid research and molecular biology. 1995 51:93-122.
1995
Bambara RA, Fay PJ, Mallaber LM. "Methods of analyzing processivity." Methods in enzymology. 1995 262:270-80.
1994 Oct 18
DeStefano JJ, Wu W, Seehra J, McCoy J, Laston D, Albone E, Fay PJ, Bambara RA. "Characterization of an RNase H deficient mutant of human immunodeficiency virus-1 reverse transcriptase having an aspartate to asparagine change at position 498." Biochimica et biophysica acta.. 1994 Oct 18; 1219(2):380-8.
1994 Oct 14
Huang L, Kim Y, Turchi JJ, Bambara RA. "Structure-specific cleavage of the RNA primer from Okazaki fragments by calf thymus RNase HI." The Journal of biological chemistry.. 1994 Oct 14; 269(41):25922-7.
1994 Oct 11
Turchi JJ, Huang L, Murante RS, Kim Y, Bambara RA. "Enzymatic completion of mammalian lagging-strand DNA replication." Proceedings of the National Academy of Sciences of the United States of America.. 1994 Oct 11; 91(21):9803-7.
1994 Sep 11
DeStefano JJ, Mallaber LM, Fay PJ, Bambara RA. "Quantitative analysis of RNA cleavage during RNA-directed DNA synthesis by human immunodeficiency and avian myeloblastosis virus reverse transcriptases." Nucleic acids research.. 1994 Sep 11; 22(18):3793-800.
1994 Jan 14
Murante RS, Huang L, Turchi JJ, Bambara RA. "The calf 5'- to 3'-exonuclease is also an endonuclease with both activities dependent on primers annealed upstream of the point of cleavage." The Journal of biological chemistry.. 1994 Jan 14; 269(2):1191-6.
1994 Jan 7
DeStefano JJ, Bambara RA, Fay PJ. "The mechanism of human immunodeficiency virus reverse transcriptase-catalyzed strand transfer from internal regions of heteropolymeric RNA templates." The Journal of biological chemistry.. 1994 Jan 7; 269(1):161-8.
1993 Oct 19
Buiser RG, Bambara RA, Fay PJ. "Pausing by retroviral DNA polymerases promotes strand transfer from internal regions of RNA donor templates to homopolymeric acceptor templates." Biochimica et biophysica acta.. 1993 Oct 19; 1216(1):20-30.
1993 Sep 11
DeStefano JJ, Mallaber LM, Fay PJ, Bambara RA. "Determinants of the RNase H cleavage specificity of human immunodeficiency virus reverse transcriptase." Nucleic acids research.. 1993 Sep 11; 21(18):4330-8.
1993 Jul 15
Turchi JJ, Bambara RA. "Completion of mammalian lagging strand DNA replication using purified proteins." The Journal of biological chemistry.. 1993 Jul 15; 268(20):15136-41.
1993 Jul 13
DeStefano JJ, Bambara RA, Fay PJ. "Parameters that influence the binding of human immunodeficiency virus reverse transcriptase to nucleic acid structures." Biochemistry.. 1993 Jul 13; 32(27):6908-15.
1993 Jan 26
Huang L, Turchi JJ, Wahl AF, Bambara RA. "Effects of the anticancer drug cis-diamminedichloroplatinum(II) on the activities of calf thymus DNA polymerase epsilon." Biochemistry.. 1993 Jan 26; 32(3):841-8.
1993
Huang L, Turchi JJ, Wahl AF, Bambara RA. "Activity of calf thymus DNA helicase E on cis-diamminedichloroplatinum (II)-damaged DNA." The Journal of biological chemistry.. 1993 268(35):26731-7.
1993
Anolik JH, Klinge CM, Bambara RA, Hilf R. "Differential impact of flanking sequences on estradiol- vs 4-hydroxytamoxifen-liganded estrogen receptor binding to estrogen responsive element DNA." The Journal of steroid biochemistry and molecular biology.. 1993 46(6):713-30.
1992 Nov 25
Turchi JJ, Murante RS, Bambara RA. "DNA substrate specificity of DNA helicase E from calf thymus." Nucleic acids research.. 1992 Nov 25; 20(22):6075-80.
1992 Nov
DeStefano JJ, Mallaber LM, Rodriguez-Rodriguez L, Fay PJ, Bambara RA. "Requirements for strand transfer between internal regions of heteropolymer templates by human immunodeficiency virus reverse transcriptase." Journal of virology.. 1992 Nov; 66(11):6370-8.
1992 Oct 15
Siegal G, Turchi JJ, Myers TW, Bambara RA. "A 5' to 3' exonuclease functionally interacts with calf DNA polymerase epsilon." Proceedings of the National Academy of Sciences of the United States of America.. 1992 Oct 15; 89(20):9377-81.
1992 Oct
Klinge CM, Bambara RA, Hilf R. "Antiestrogen-liganded estrogen receptor interaction with estrogen responsive element DNA in vitro." The Journal of steroid biochemistry and molecular biology.. 1992 Oct; 43(4):249-62.
1992 Sep 22
Turchi JJ, Siegal G, Bambara RA. "DNA helicase E and DNA polymerase epsilon functionally interact for displacement synthesis." Biochemistry.. 1992 Sep 22; 31(37):9008-15.
1992 Jul 15
DeStefano JJ, Buiser RG, Mallaber LM, Fay PJ, Bambara RA. "Parameters that influence processive synthesis and site-specific termination by human immunodeficiency virus reverse transcriptase on RNA and DNA templates." Biochimica et biophysica acta.. 1992 Jul 15; 1131(3):270-80.
1992 Jul 5
Siegal G, Turchi JJ, Jessee CB, Myers TW, Bambara RA. "A novel DNA helicase from calf thymus." The Journal of biological chemistry.. 1992 Jul 5; 267(19):13629-35.
1992 Mar 1
Klinge CM, Peale FV, Hilf R, Bambara RA, Zain S. "Cooperative estrogen receptor interaction with consensus or variant estrogen responsive elements in vitro." Cancer research.. 1992 Mar 1; 52(5):1073-81.
1992 Feb 25
Siegal G, Turchi JJ, Jessee CB, Mallaber LM, Bambara RA, Myers TW. "Structural relationships between two forms of DNA polymerase epsilon from calf thymus." The Journal of biological chemistry.. 1992 Feb 25; 267(6):3991-9.
1992
Kwon, O.; Bambara, R. A.;. "Characteristics of ATPgS-Induced Complexes Formed between Escherichia coli DNA Polymerase III Holoenzyme and Primed DNA". Mol. Cells (Korea). 1992; 2(3): 53-60. Link
1992
Klinge CM, Bambara RA, Hilf R. "What differentiates antiestrogen-liganded vs estradiol-liganded estrogen receptor action?" Oncology research. 1992 4(4-5):137-44.
1991 Jul 15
Buiser RG, DeStefano JJ, Mallaber LM, Fay PJ, Bambara RA. "Requirements for the catalysis of strand transfer synthesis by retroviral DNA polymerases." The Journal of biological chemistry.. 1991 Jul 15; 266(20):13103-9.
1991 Apr 25
DeStefano JJ, Buiser RG, Mallaber LM, Myers TW, Bambara RA, Fay PJ. "Polymerization and RNase H activities of the reverse transcriptases from avian myeloblastosis, human immunodeficiency, and Moloney murine leukemia viruses are functionally uncoupled." The Journal of biological chemistry.. 1991 Apr 25; 266(12):7423-31.
1991 Apr 15
Ishibe Y, Klinge CM, Hilf R, Bambara RA. "Estrogen receptor alters the topology of plasmid DNA containing estrogen responsive elements." Biochemical and biophysical research communications.. 1991 Apr 15; 176(1):486-91.
1991 Jan 17
Bambara RA, Jessee CB. "Properties of DNA polymerases delta and epsilon, and their roles in eukaryotic DNA replication." Biochimica et biophysica acta.. 1991 Jan 17; 1088(1):11-24.
1991
DeStefano JJ, Buiser RG, Mallaber LM, Bambara RA, Fay PJ. "Human immunodeficiency virus reverse transcriptase displays a partially processive 3' to 5' endonuclease activity." The Journal of biological chemistry.. 1991 266(36):24295-301.
1991
Thomas DC, Roberts JD, Sabatino RD, Myers TW, Tan CK, Downey KM, So AG, Bambara RA, Kunkel TA. "Fidelity of mammalian DNA replication and replicative DNA polymerases." Biochemistry.. 1991 30(51):11751-9.
1990 Sep 1
Sabatino RD, Myers TW, Bambara RA. "Substrate specificity of the exonuclease associated with calf DNA polymerase." Cancer research.. 1990 Sep 1; 50(17):5340-4.
1990 Aug 17
Burgers PM, Bambara RA, Campbell JL, Chang LM, Downey KM, Hübscher U, Lee MY, Linn SM, So AG, Spadari S. "Revised nomenclature for eukaryotic DNA polymerases." European journal of biochemistry. 1990 Aug 17; 191(3):617-8.
1990 Jul
Ludwig LB, Klinge CM, Peale FV, Bambara RA, Zain S, Hilf R. "A microtiter well assay for quantitative measurement of estrogen receptor binding to estrogen-responsive elements." Molecular endocrinology.. 1990 Jul; 4(7):1027-33.
1990 Jun
Klinge CM, Bambara RA, Zain S, Hilf R. "Nuclease sensitivity of estradiol-charged estrogen receptor binding sites in nuclei isolated from normal and neoplastic rat mammary tissues." Journal of steroid biochemistry.. 1990 Jun; 36(1-2):7-14.
1990 Jan
Bodner JB, Bambara RA. "Selective inhibition of DNA primase activity associated with DNA polymerase alpha from calf thymus." Cancer biochemistry biophysics. 1990 Jan; 11(1):7-12.
1990
Bambara, R. A.; yers, T. W.; Sabatino, R. D.;. "DNA Polymerase Delta, in The Eukaryotic Nucleus". Molecular Biochemistry and Macromolecular Assemblies. Eds., Strauss, P. and S. Wilson. Telford Press, Caldwell, NJ. 1990; 1(3): 69-94. Link
1990
Myers, T. W.; Bambara, R. A. ;. "Proliferating Cell Nuclear Antigen Dependent and Independent Forms of Calf Thymus DNA Polymerase Delta". UCLA Symposia on Molecular and Cellular Biology, New Series. Eds., Srere, P., M. Jones and C. Mathews. Alan R. Liss, Inc., NY. 1990; 134(3): 165-180. Link
1989 Nov 25
Cripps-Wolfman J, Henshaw EC, Bambara RA. "Alterations in the phosphorylation and activity of DNA polymerase alpha correlate with the change in replicative DNA synthesis as quiescent cells re-enter the cell cycle." The Journal of biological chemistry.. 1989 Nov 25; 264(33):19478-86.
1989 Oct 31
Peale FV, Ishibe Y, Klinge CM, Zain S, Hilf R, Bambara RA. "Rapid purification of the estrogen receptor by sequence-specific DNA affinity chromatography." Biochemistry.. 1989 Oct 31; 28(22):8671-5.
1989 Sep
Klinge CM, Knox DT, Bambara RA, Zain S, Hilf R. "Antiestrogen(4-hydroxytamoxifen)-charged estrogen receptor binding to nuclei from normal and neoplastic rat mammary tissues is not affected by host hormonal status." Journal of steroid biochemistry.. 1989 Sep; 33(3):335-40.
1989 Jun 15
Liu YC, Bambara RA. "Gene expression of PCNA/cyclin in adult tissues and the R3230AC mammary tumor of rat." Biochemical and biophysical research communications.. 1989 Jun 15; 161(2):873-82.
1989 Apr 4
Liu YC, Marraccino RL, Keng PC, Bambara RA, Lord EM, Chou WG, Zain SB. "Requirement for proliferating cell nuclear antigen expression during stages of the Chinese hamster ovary cell cycle." Biochemistry.. 1989 Apr 4; 28(7):2967-74.
1989 Mar 1
Klinge CM, Bambara RA, Zain S, Hilf R. "Effects of host hormonal status on binding of activated estrogen receptor to nuclei from R3230AC and 7,12-dimethylbenz[a]anthracene-induced mammary tumors." Cancer research.. 1989 Mar 1; 49(5):1165-70.
1989
Kunkel, T. A.; Bambara, R. A.; Bebenek, K.; Roberts, J. D.; Sabatino, R. D.; Smith, M. P.; Soni, A. ;. "Analysis of Mutational Mechanisms with Eukaryotic DNA Polymerases". UCLA Symposia on Molecular and Cellular Biology, New Series, Vol. 82, Eds., E. Friedberg and Hanawalt, P.. Alan R. Liss, Inc., NY. 1989; 1(3): 521-528. Link
1988 Apr 19
Sabatino RD, Myers TW, Bambara RA, Kwon-Shin O, Marraccino RL, Frickey PH. "Calf thymus DNA polymerases alpha and delta are capable of highly processive DNA synthesis." Biochemistry.. 1988 Apr 19; 27(8):2998-3004.
1988 Apr 5
Sabatino RD, Bambara RA. "Properties of the 3' to 5' exonuclease associated with calf DNA polymerase delta." Biochemistry.. 1988 Apr 5; 27(7):2266-71.
1988 Feb
Peale FV, Ludwig LB, Zain S, Hilf R, Bambara RA. "Properties of a high-affinity DNA binding site for estrogen receptor." Proceedings of the National Academy of Sciences of the United States of America.. 1988 Feb; 85(4):1038-42.
1987 Sep
Lerea CC, Klinge CM, Bambara RA, Zain S, Hilf R. "Characterization of a cytosolic inhibitor of calf estrogen receptor binding to nuclei." Endocrinology.. 1987 Sep; 121(3):1146-54.
1987 Jul
Kunkel TA, Sabatino RD, Bambara RA. "Exonucleolytic proofreading by calf thymus DNA polymerase delta." Proceedings of the National Academy of Sciences of the United States of America.. 1987 Jul; 84(14):4865-9.
1987 Jun 1
Klinge CM, Bambara RA, Zain S, Hilf R. "Estrogen receptor binding to nuclei from normal and neoplastic rat mammary tissues in vitro." Cancer research.. 1987 Jun 1; 47(11):2852-9.
1987 Feb 15
Kwon-Shin O, Bodner JB, McHenry CS, Bambara RA. "Properties of initiation complexes formed between Escherichia coli DNA polymerase III holoenzyme and primed DNA in the absence of ATP." The Journal of biological chemistry.. 1987 Feb 15; 262(5):2121-30.
1987
Marraccino RL, Wahl AF, Keng PC, Lord EM, Bambara RA. "Cell cycle dependent activities of DNA polymerases alpha and delta in Chinese hamster ovary cells." Biochemistry.. 1987 26(24):7864-70.
1986 Jun 5
LaDuca RJ, Crute JJ, McHenry CS, Bambara RA. "The beta subunit of the Escherichia coli DNA polymerase III holoenzyme interacts functionally with the catalytic core in the absence of other subunits." The Journal of biological chemistry.. 1986 Jun 5; 261(16):7550-7.
1986 Jan 14
Crute JJ, Wahl AF, Bambara RA. "Purification and characterization of two new high molecular weight forms of DNA polymerase delta." Biochemistry.. 1986 Jan 14; 25(1):26-36.
1986 Jan
Crute JJ, Wahl AF, Bambara RA, Murant RS, Gibson SL, Hilf R. "Inhibition of mammalian DNA polymerases by hematoporphyrin derivative and photoradiation." Cancer research.. 1986 Jan; 46(1):153-9.
1986
Hockensmith JW, Wahl AF, Kowalski S, Bambara RA. "Purification of a calf thymus DNA-dependent adenosinetriphosphatase that prefers a primer-template junction effector." Biochemistry.. 1986 25(24):7812-21.
1986
Wahl AF, Crute JJ, Sabatino RD, Bodner JB, Marraccino RL, Harwell LW, Lord EM, Bambara RA. "Properties of two forms of DNA polymerase delta from calf thymus." Biochemistry.. 1986 25(24):7821-7.
1985 Jun
Cushing CL, Bambara RA, Hilf R. "Interactions of estrogen-receptor and antiestrogen-receptor complexes with nuclei in vitro." Endocrinology.. 1985 Jun; 116(6):2419-29.
1985 Feb
Peale FV, Bond J, Hilf R, Bambara R. "An analysis of the decrease in the assayed level of charged bovine estrogen receptor observed at physiological ionic strength." Journal of steroid biochemistry.. 1985 Feb; 22(2):161-7.
1985
Bambara RA, Crute JJ, Wahl AF. "Is Ap4A an activator of eukaryotic DNA replication?" Cancer investigation. 1985 3(5):473-9.
1984 Sep 11
Lawton KG, Wierowski JV, Schechter S, Hilf R, Bambara RA. "Analysis of the mechanism of ATP stimulation of calf thymus DNA alpha-polymerase." Biochemistry.. 1984 Sep 11; 23(19):4294-300.
1984 May
Pratt K, Wierowski JV, Hilf R, Bambara RA. "Bovine estrogen receptor binds chromatin at pre-existing nuclease hypersensitive sites." Molecular and cellular endocrinology.. 1984 May; 35(2-3):205-14.
1984 Apr 24
Wahl AF, Kowalski SP, Harwell LW, Lord EM, Bambara RA. "Immunoaffinity purification and properties of a high molecular weight calf thymus DNA alpha-polymerase." Biochemistry.. 1984 Apr 24; 23(9):1895-9.
1983 Oct 25
LaDuca RJ, Fay PJ, Chuang C, McHenry CS, Bambara RA. "Site-specific pausing of deoxyribonucleic acid synthesis catalyzed by four forms of Escherichia coli DNA polymerase III." Biochemistry.. 1983 Oct 25; 22(22):5177-88.
1983 Sep 25
Crute JJ, LaDuca RJ, Johanson KO, McHenry CS, Bambara RA. "Excess beta subunit can bypass the ATP requirement for highly processive synthesis by the Escherichia coli DNA polymerase III holoenzyme." The Journal of biological chemistry.. 1983 Sep 25; 258(18):11344-9.
1983 Aug
Wahl AF, Hockensmith JW, Kowalski S, Bambara RA. "Alternative explanation for excision repair deficiency caused by the polAex1 mutation." Journal of bacteriology.. 1983 Aug; 155(2):922-5.
1983 May 25
Wierowski JV, Lawton KG, Hockensmith JW, Bambara RA. "Stimulation of calf thymus DNA alpha-polymerase by ATP." The Journal of biological chemistry.. 1983 May 25; 258(10):6250-4.
1982 May 25
Fay PJ, Johanson KO, McHenry CS, Bambara RA. "Size classes of products synthesized processively by two subassemblies of Escherichia coli DNA polymerase III holoenzyme." The Journal of biological chemistry.. 1982 May 25; 257(10):5692-9.
1981 Aug 10
Villani G, Fay PJ, Bambara RA, Lehman IR. "Elongation of RNA-primed DNA templates by DNA polymerase alpha from Drosophila melanogaster embryos." The Journal of biological chemistry.. 1981 Aug 10; 256(15):8202-7.
1981 Apr
Matson SW, Bambara RA. "Short deoxyribonucleic acid repair patch length in Escherichia coli is determined by the processive mechanism of deoxyribonucleic acid polymerase I." Journal of bacteriology.. 1981 Apr; 146(1):275-84.
1981 Jan 29
Matson SW, Bambara RA. "Duplex DNA binding activity of the avian myeloblastosis virus DNA polymerase." Biochimica et biophysica acta.. 1981 Jan 29; 652(1):29-38.
1981 Jan 25
Fay PJ, Johanson KO, McHenry CS, Bambara RA. "Size classes of products synthesized processively by DNA polymerase III and DNA polymerase III holoenzyme of Escherichia coli." The Journal of biological chemistry.. 1981 Jan 25; 256(2):976-83.
1981 Jan 6
Hockensmith JW, Bambara RA. "Kinetic characteristics which distinguish two forms of calf thymus DNA polymerase alpha." Biochemistry.. 1981 Jan 6; 20(1):227-32.
1980 May 13
Matson SW, Fay PJ, Bambara RA. "Mechanism of inhibition of the avian myeloblastosis virus deoxyribonucleic acid polymerase by adriamycin." Biochemistry.. 1980 May 13; 19(10):2089-96.
1980
Bambara, R.; Uyemura, D.;. "Assessment of Processivity in DNA Polymerase Mechanisms". Comments on Mol. and Cell. Biophys. 1980; 1(3): 69-80. Link
1978 Nov 10
Matson SW, Capaldo-Kimball FN, Bambara RA. "On the processive mechanism of Escherichia coli DNA Polymerase I. The polA5 mutation." The Journal of biological chemistry.. 1978 Nov 10; 253(21):7851-6.
1978 Jan 25
Bambara RA, Uyemura D, Choi T. "On the processive mechanism of Escherichia coli DNA polymerase I. Quantitative assessment of processivity." The Journal of biological chemistry.. 1978 Jan 25; 253(2):413-23.
1976 Jul 10
Bambara RA, Uyemura D, Lehman IR. "On the processive mechanism of Escherichia coli DNA polymerase I. Delayed initiation of polymerization." The Journal of biological chemistry.. 1976 Jul 10; 251(13):4090-4.
1975 Nov 25
Uyemura D, Bambara R, Lehman IR. "On the processive mechanism of Escherichia coli DNA polymerase I." The Journal of biological chemistry.. 1975 Nov 25; 250(22):8577-84.
1975 Jun 25
Bambara R, Wu R. "DNA sequence analysis. Terminal sequences of bacteriophage phi80." The Journal of biological chemistry.. 1975 Jun 25; 250(12):4607-18.
1975 Feb
Wu R, Bambara R, Jay E. "Recent advances in DNA sequence analysis." CRC critical reviews in biochemistry. 1975 Feb; 2(4):455-512.
1975
Dykes, G.; Bambara, R.; Marians, K.; Wu, R.;. "On the statistical significance of primary structural features found in DNA-protein interaction sites". Nucleic Acids Res. 1975; 02(33): 327-45. Link
1974 Nov
Bambara R, Jay E, Wu R. "DNA sequence analysis: a formula to predict electrophoretic mobilities of oligonucleotides on cellulose acetate." Nucleic acids research.. 1974 Nov; 1(11):1503-20.
1974 Mar
Jay E, Bambara R, Padmanabhan R, Wu R. "DNA sequence analysis: a general, simple and rapid method for sequencing large oligodeoxyribonucleotide fragments by mapping." Nucleic acids research.. 1974 Mar; 1(3):331-53.
1974
Wu R, Padmanabhan R, Bambara R. "Nucleotide sequence analysis of bacteriophage DNA." Methods in enzymology. 1974 29:231-53.
1973 Oct 1
Ghangas GS, Jay E, Bambara R, Wu R. "Nucleotide sequence analysis of DNA. XI. The 3' terminal sequences of bacteriophage lambda and phi 80 DNA." Biochemical and biophysical research communications.. 1973 Oct 1; 54(3):998-1007.
1973 Apr 25
Bambara R, Padmanabhan R, Wu R. "Nucleotide sequence analysis of DNA. X. Complete nucleotide sequence of the cohesive ends of bacteriophage phi80 DNA." Journal of molecular biology.. 1973 Apr 25; 75(4):741-4.
1972
Ryan, F. J.; Bambara, R. A.; Loach, P. A.;. "Structure of Porphyrins in Relation to Reversible Oxidation and Reduction Reactions". Bioorganic Chem. 1972; 2(3): 44-58. Link
1971
Loach, P. A.; Bambara, R. A.; Ryan, F. J. ;. "Identification of the Major Ultraviolet Absorbance Photochanges in Photosynthetic Systems". Photochem. Photobiol. 1971; 13(3): 247-257. Link

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