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Ted B. Begenisich, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 711
Rochester, NY 14642

Journal Articles

Showing all 71 journal articles available.

2012 Mar
Thompson J, Begenisich T. "Selectivity filter gating in large-conductance Ca(2+)-activated K+ channels." The Journal of general physiology. 2012 Mar; 139(3):235-44.
2012 Feb
Almassy J, Won JH, Begenisich TB, Yule DI. "Apical Ca2+-activated potassium channels in mouse parotid acinar cells." The Journal of general physiology. 2012 Feb; 139(2):121-33.
2012 Jan
Almassy J, Begenisich T. "The LRRC26 protein selectively alters the efficacy of BK channel activators." Molecular pharmacology. 2012 Jan; 81(1):21-30. Epub 2011 Oct 07.
2009 Apr
Romanenko VG, Roser K, Melvin JE, Begenisich T. "The role of cell cholesterol and the cytoskeleton in the interaction between IK1 and maxi-K channels." American journal of physiology. Cell physiology. 2009 Apr; 296(4):C878-88. Epub 2009 Jan 28.
2009
Thompson, J.; Begenisich, T. "Mechanistic details of BK chanel inhibition by the intermediate conductance, Ca (2+)-activated K channel." Channels. 2009; 3: 194-204.
2008 Mar
Nakamoto T, Romanenko VG, Takahashi A, Begenisich T, Melvin JE. "Apical maxi-K (KCa1.1) channels mediate K+ secretion by the mouse submandibular exocrine gland." American journal of physiology. Cell physiology. 2008 Mar; 294(3):C810-9. Epub 2008 Jan 23.
2007 Jun 1
Romanenko VG, Nakamoto T, Srivastava A, Begenisich T, Melvin JE. "Regulation of membrane potential and fluid secretion by Ca2+-activated K+ channels in mouse submandibular glands." The Journal of physiology. 2007 Jun 1; 581(Pt 2):801-17. Epub 2007 Mar 22.
2007 Jun
Nakamoto T, Srivastava A, Romanenko VG, Ovitt CE, Perez-Cornejo P, Arreola J, Begenisich T, Melvin JE. "Functional and molecular characterization of the fluid secretion mechanism in human parotid acinar cells." American journal of physiology. Regulatory, integrative and comparative physiology. 2007 Jun; 292(6):R2380-90. Epub 2007 Mar 08.
2006 Sep 22
Romanenko V, Nakamoto T, Srivastava A, Melvin JE, Begenisich T. "Molecular identification and physiological roles of parotid acinar cell maxi-K channels." The Journal of biological chemistry. 2006 Sep 22; 281(38):27964-72. Epub 2006 Jul 27.
2006 Feb
Thompson J, Begenisich T. "Membrane-delimited inhibition of maxi-K channel activity by the intermediate conductance Ca2+-activated K channel." The Journal of general physiology. 2006 Feb; 127(2):159-69. Epub 2006 Jan 17.
2006
Quinn CC, Begenisich T. "Pharmacology and surface electrostatics of the K channel outer pore vestibule." The Journal of membrane biology. 2006 212(1):51-60. Epub 2007 Jan 06.
2005 Jun
Thompson J, Begenisich T. "Two stable, conducting conformations of the selectivity filter in Shaker K+ channels." The Journal of general physiology. 2005 Jun; 125(6):619-29. Epub 2005 May 16.
2005
Melvin JE, Yule D, Shuttleworth T, Begenisich T. "Regulation of fluid and electrolyte secretion in salivary gland acinar cells." Annual review of physiology. 2005 67:445-69.
2004 Nov 12
Begenisich T, Nakamoto T, Ovitt CE, Nehrke K, Brugnara C, Alper SL, Melvin JE. "Physiological roles of the intermediate conductance, Ca2+-activated potassium channel Kcnn4." The Journal of biological chemistry. 2004 Nov 12; 279(46):47681-7. Epub 2004 Sep 03.
2003 Aug
Thompson J, Begenisich T. "External TEA block of shaker K+ channels is coupled to the movement of K+ ions within the selectivity filter." The Journal of general physiology. 2003 Aug; 122(2):239-46.
2003 May 15
Thompson J, Begenisich T. "Functional identification of ion binding sites at the internal end of the pore in Shaker K+ channels." The Journal of physiology. 2003 May 15; 549(Pt 1):107-20. Epub 2003 Mar 28.
2003 Feb
Nehrke K, Quinn CC, Begenisich T. "Molecular identification of Ca2+-activated K+ channels in parotid acinar cells." American journal of physiology. Cell physiology. 2003 Feb; 284(2):C535-46. Epub 2002 Oct 16.
2002 Nov 15
Arreola J, Begenisich T, Nehrke K, Nguyen HV, Park K, Richardson L, Yang B, Schutte BC, Lamb FS, Melvin JE. "Secretion and cell volume regulation by salivary acinar cells from mice lacking expression of the Clcn3 Cl- channel gene." The Journal of physiology. 2002 Nov 15; 545(Pt 1):207-16.
2002 May 15
Arreola J, Begenisich T, Melvin JE. "Conformation-dependent regulation of inward rectifier chloride channel gating by extracellular protons." The Journal of physiology. 2002 May 15; 541(Pt 1):103-12.
2001 Aug 1
Quinn CC, Begenisich T. "The influence of surface charges on quaternary ammonium block of shaker K+ channels." The Journal of membrane biology. 2001 Aug 1; 182(3):233-43.
2001 Jul 1
Park K, Begenisich T, Melvin JE. "Protein kinase A activation phosphorylates the rat ClC-2 Cl- channel but does not change activity." The Journal of membrane biology. 2001 Jul 1; 182(1):31-7.
2001 May
Thompson J, Begenisich T. "Affinity and location of an internal K+ ion binding site in shaker K channels." The Journal of general physiology. 2001 May; 117(5):373-84.
2000 Jun
Thompson J, Begenisich T. "Interaction between quaternary ammonium ions in the pore of potassium channels. Evidence against an electrostatic repulsion mechanism." The Journal of general physiology. 2000 Jun; 115(6):769-82.
2000 May
Thompson J, Begenisich T. "Electrostatic interaction between charybdotoxin and a tetrameric mutant of Shaker K(+) channels." Biophysical journal. 2000 May; 78(5):2382-91.
1998 Oct
Stampe P, Arreola J, Pérez-Cornejo P, Begenisich T. "Nonindependent K+ movement through the pore in IRK1 potassium channels." The Journal of general physiology. 1998 Oct; 112(4):475-84.
1998 May 15
Park K, Arreola J, Begenisich T, Melvin JE. "Comparison of voltage-activated Cl- channels in rat parotid acinar cells with ClC-2 in a mammalian expression system." The Journal of membrane biology. 1998 May 15; 163(2):87-95.
1998 Mar
Perez-Cornejo P, Stampe P, Begenisich T. "Proton probing of the charybdotoxin binding site of Shaker K+ channels." The Journal of general physiology. 1998 Mar; 111(3):441-50.
1998 Jan
Arreola J, Melvin JE, Begenisich T. "Differences in regulation of Ca(2+)-activated Cl- channels in colonic and parotid secretory cells." The American journal of physiology. 1998 Jan; 274(1 Pt 1):C161-6.
1998
Begenisich T. "Determining ion channel permeation properties." Methods in enzymology. 1998 293:383-90.
1998
Stampe P, Begenisich T. "Unidirectional fluxes through ion channels expressed in Xenopus oocytes." Methods in enzymology. 1998 293:556-64.
1996 Jul
Arreola J, Melvin JE, Begenisich T. "Activation of calcium-dependent chloride channels in rat parotid acinar cells." The Journal of general physiology. 1996 Jul; 108(1):35-47.
1996 Apr
Stampe P, Begenisich T. "Unidirectional K+ fluxes through recombinant Shaker potassium channels expressed in single Xenopus oocytes." The Journal of general physiology. 1996 Apr; 107(4):449-57.
1996 Jan 15
Arreola J, Park K, Melvin JE, Begenisich T. "Three distinct chloride channels control anion movements in rat parotid acinar cells." The Journal of physiology. 1996 Jan 15; 490 ( Pt 2):351-62.
1995 Sep
Arreola J, Melvin JE, Begenisich T. "Inhibition of Ca(2+)-dependent Cl- channels from secretory epithelial cells by low internal pH." The Journal of membrane biology. 1995 Sep; 147(1):95-104.
1995 May 1
Arreola J, Melvin JE, Begenisich T. "Volume-activated chloride channels in rat parotid acinar cells." The Journal of physiology. 1995 May 1; 484 ( Pt 3):677-87.
1995 Feb
Spires S, Begenisich T. "Voltage-independent gating transitions in squid axon potassium channels." Biophysical journal. 1995 Feb; 68(2):491-500.
1994 Oct
Spires S, Begenisich T. "Modulation of potassium channel gating by external divalent cations." The Journal of general physiology. 1994 Oct; 104(4):675-92.
1994 Jun
Pérez-Cornejo P, Begenisich T. "The multi-ion nature of the pore in Shaker K+ channels." Biophysical journal. 1994 Jun; 66(6):1929-38.
1993 Feb
Nealey T, Spires S, Eatock RA, Begenisich T. "Potassium channels in squid neuron cell bodies: comparison to axonal channels." The Journal of membrane biology. 1993 Feb; 132(1):13-25.
1993
Arreola J, Spires S, Begenisich T. "Na+ channels in cardiac and neuronal cells derived from a mouse embryonal carcinoma cell line." The Journal of physiology. 1993 472:289-303.
1992 Aug
Spires S, Begenisich T. "Chemical properties of the divalent cation binding site on potassium channels." The Journal of general physiology. 1992 Aug; 100(2):181-93.
1992 Jan
Spires S, Begenisich T. "Modification of potassium channel kinetics by amino group reagents." The Journal of general physiology. 1992 Jan; 99(1):109-29.
1992
Begenisich T. "Ion channel selectivity, permeation, and block." Methods in enzymology. 1992 207:92-100.
1991 Jun
Smith-Maxwell CJ, Eatock RA, Begenisich T. "Induction of K-channel expression in a neuroblastoma cell line." Journal of neurobiology. 1991 Jun; 22(4):327-41.
1990 Oct
Spires S, Begenisich T. "Modification of potassium channel kinetics by histidine-specific reagents." The Journal of general physiology. 1990 Oct; 96(4):757-75.
1989 May
Walsh KB, Begenisich TB, Kass RS. "Beta-adrenergic modulation of cardiac ion channels. Differential temperature sensitivity of potassium and calcium currents." The Journal of general physiology. 1989 May; 93(5):841-54.
1989 Apr
Bennett PB, Kass R, Begenisich T. "Nonstationary fluctuation analysis of the delayed rectifier K channel in cardiac Purkinje fibers. Actions of norepinephrine on single-channel current." Biophysical journal. 1989 Apr; 55(4):731-8.
1989 Feb
Spires S, Begenisich T. "Pharmacological and kinetic analysis of K channel gating currents." The Journal of general physiology. 1989 Feb; 93(2):263-83.
1988 Feb
Walsh KB, Begenisich TB, Kass RS. "Beta-adrenergic modulation in the heart. Independent regulation of K and Ca channels." Pflügers Archiv : European journal of physiology. 1988 Feb; 411(2):232-4.
1987 Sep
Smith-Maxwell C, Begenisich T. "Guanidinium analogues as probes of the squid axon sodium pore. Evidence for internal surface charges." The Journal of general physiology. 1987 Sep; 90(3):361-74.
1987 Sep
Bennett PB, Begenisich TB. "Catecholamines modulate the delayed rectifying potassium current (IK) in guinea pig ventricular myocytes." Pflügers Archiv : European journal of physiology. 1987 Sep; 410(1-2):217-9.
1986 Jul
Chabala LD, Morello RS, Busath D, Danko M, Smith-Maxwell CJ, Begenisich T. "Capture, transport, and maintenance of live squid (Loligo pealei) for electrophysiological studies." Pflügers Archiv : European journal of physiology. 1986 Jul; 407(1):105-8.
1986 Apr
Bennett P, McKinney L, Begenisich T, Kass RS. "Adrenergic modulation of the delayed rectifier potassium channel in calf cardiac Purkinje fibers." Biophysical journal. 1986 Apr; 49(4):839-48.
1986 Feb
Danko M, Smith-Maxwell C, McKinney L, Begenisich T. "Block of sodium channels by internal mono- and divalent guanidinium analogues. Modulation by sodium ion concentration." Biophysical journal. 1986 Feb; 49(2):509-19.
1985 Oct
Bennett PB, McKinney LC, Kass RS, Begenisich T. "Delayed rectification in the calf cardiac Purkinje fiber. Evidence for multiple state kinetics." Biophysical journal. 1985 Oct; 48(4):553-67.
1985
McKinney LC, Danko M, Smith CJ, Begenisich T. "Permeability of the squid giant axon to organic cations and small nonelectrolytes." The Journal of membrane biology. 1985 83(1-2):177-86.
1984 Jul
Morello RS, Begenisich T, Yeh JZ. "Determination of the active form of phenytoin." The Journal of pharmacology and experimental therapeutics. 1984 Jul; 230(1):156-61.
1983 Nov
Begenisich T, Danko M. "Hydrogen ion block of the sodium pore in squid giant axons." The Journal of general physiology. 1983 Nov; 82(5):599-618.
1982 Oct
Busath D, Begenisich T. "Unidirectional sodium and potassium fluxes through the sodium channel of squid giant axons." Biophysical journal. 1982 Oct; 40(1):41-9.
1981 May
Begenisich T, Busath D. "Sodium flux ratio in voltage-clamped squid giant axons." The Journal of general physiology. 1981 May; 77(5):489-502.
1980 Oct
Begenisich TB, Cahalan MD. "Sodium channel permeation in squid axons. I: Reversal potential experiments." The Journal of physiology. 1980 Oct; 307:217-42.
1980 Oct
Begenisich TB, Cahalan MD. "Sodium channel permeation in squid axons. II: Non-independence and current-voltage relations." The Journal of physiology. 1980 Oct; 307:243-57.
1980 Sep
Morello R, Begenisich T, Trzos W, Reed JK. "Interaction of nonylguanidine with the sodium channel." Biophysical journal. 1980 Sep; 31(3):435-40.
1980 Jul
Begenisich T, De Weer P. "Potassium flux ratio in voltage-clamped squid giant axons." The Journal of general physiology. 1980 Jul; 76(1):83-98.
1979 Aug
Begenisich T. "Conditioning hyperpolarization-induced delays in the potassium channels of myelinated nerve." Biophysical journal. 1979 Aug; 27(2):257-65.
1977 Oct 20
Begenisich T, De Weer P. "Ionic interactions in the potassium channel of squid giant axons." Nature. 1977 Oct 20; 269(5630):710-1.
1976 Aug
Cahalan M, Begenisich T. "Sodium channel selectivity. Dependence on internal permeant ion concentration." The Journal of general physiology. 1976 Aug; 68(2):111-25.
1975 Oct 9
Goldman L, Hahin R, Begenisich T. "Letter: Sodium flux, action potential and temperature dependence." Nature. 1975 Oct 9; 257(5526):516-7.
1975 Aug
Begenisich T, Stevens CF. "How many conductance states do potassium channels have?" Biophysical journal. 1975 Aug; 15(8):843-6.
1975 Jul
Begenisich T. "Magnitude and location of surface charges on Myxicola giant axons." The Journal of general physiology. 1975 Jul; 66(1):47-65.
1974 Jun
Begenisich T, Lynch C. "Effects of internal divalent cations on voltage-clamped squid axons." The Journal of general physiology. 1974 Jun; 63(6):675-89.