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Ted B. Begenisich, Ph.D.

Contact Information

University of Rochester
School of Medicine and Dentistry
601 Elmwood Ave., Box 711
Rochester, NY 14642

Journal Articles

Showing all 71 journal articles available.

2012
Thompson J, Begenisich T. "Selectivity filter gating in large-conductance Ca(2+)-activated K+ channels." The Journal of general physiology. 2012 139(3):235-44.
2012
Almassy J, Won JH, Begenisich TB, Yule DI. "Apical Ca2+-activated potassium channels in mouse parotid acinar cells." The Journal of general physiology. 2012 139(2):121-33.
2012
Almassy J, Begenisich T. "The LRRC26 protein selectively alters the efficacy of BK channel activators." Molecular pharmacology. 2012 81(1):21-30. Epub 2011 Oct 07.
2009
Romanenko VG, Roser K, Melvin JE, Begenisich T. "The role of cell cholesterol and the cytoskeleton in the interaction between IK1 and maxi-K channels." American journal of physiology. Cell physiology. 2009 296(4):C878-88. Epub 2009 Jan 28.
2009
Thompson, J.; Begenisich, T. "Mechanistic details of BK chanel inhibition by the intermediate conductance, Ca (2+)-activated K channel." Channels. 2009; 3: 194-204. Link
2008
Nakamoto T, Romanenko VG, Takahashi A, Begenisich T, Melvin JE. "Apical maxi-K (KCa1.1) channels mediate K+ secretion by the mouse submandibular exocrine gland." American journal of physiology. Cell physiology. 2008 294(3):C810-9. Epub 2008 Jan 23.
2007
Romanenko VG, Nakamoto T, Srivastava A, Begenisich T, Melvin JE. "Regulation of membrane potential and fluid secretion by Ca2+-activated K+ channels in mouse submandibular glands." The Journal of physiology. 2007 581(Pt 2):801-17. Epub 2007 Mar 22.
2007
Nakamoto T, Srivastava A, Romanenko VG, Ovitt CE, Perez-Cornejo P, Arreola J, Begenisich T, Melvin JE. "Functional and molecular characterization of the fluid secretion mechanism in human parotid acinar cells." American journal of physiology. Regulatory, integrative and comparative physiology. 2007 292(6):R2380-90. Epub 2007 Mar 08.
2006
Romanenko V, Nakamoto T, Srivastava A, Melvin JE, Begenisich T. "Molecular identification and physiological roles of parotid acinar cell maxi-K channels." The Journal of biological chemistry. 2006 281(38):27964-72. Epub 2006 Jul 27.
2006
Thompson J, Begenisich T. "Membrane-delimited inhibition of maxi-K channel activity by the intermediate conductance Ca2+-activated K channel." The Journal of general physiology. 2006 127(2):159-69. Epub 2006 Jan 17.
2006
Quinn CC, Begenisich T. "Pharmacology and surface electrostatics of the K channel outer pore vestibule." The Journal of membrane biology. 2006 212(1):51-60. Epub 2007 Jan 06.
2005
Thompson J, Begenisich T. "Two stable, conducting conformations of the selectivity filter in Shaker K+ channels." The Journal of general physiology. 2005 125(6):619-29. Epub 2005 May 16.
2005
Melvin JE, Yule D, Shuttleworth T, Begenisich T. "Regulation of fluid and electrolyte secretion in salivary gland acinar cells." Annual review of physiology. 2005 67:445-69.
2004
Begenisich T, Nakamoto T, Ovitt CE, Nehrke K, Brugnara C, Alper SL, Melvin JE. "Physiological roles of the intermediate conductance, Ca2+-activated potassium channel Kcnn4." The Journal of biological chemistry. 2004 279(46):47681-7. Epub 2004 Sep 03.
2003
Thompson J, Begenisich T. "External TEA block of shaker K+ channels is coupled to the movement of K+ ions within the selectivity filter." The Journal of general physiology. 2003 122(2):239-46.
2003
Thompson J, Begenisich T. "Functional identification of ion binding sites at the internal end of the pore in Shaker K+ channels." The Journal of physiology. 2003 549(Pt 1):107-20. Epub 2003 Mar 28.
2003
Nehrke K, Quinn CC, Begenisich T. "Molecular identification of Ca2+-activated K+ channels in parotid acinar cells." American journal of physiology. Cell physiology. 2003 284(2):C535-46. Epub 2002 Oct 16.
2002
Arreola J, Begenisich T, Nehrke K, Nguyen HV, Park K, Richardson L, Yang B, Schutte BC, Lamb FS, Melvin JE. "Secretion and cell volume regulation by salivary acinar cells from mice lacking expression of the Clcn3 Cl- channel gene." The Journal of physiology. 2002 545(Pt 1):207-16.
2002
Arreola J, Begenisich T, Melvin JE. "Conformation-dependent regulation of inward rectifier chloride channel gating by extracellular protons." The Journal of physiology. 2002 541(Pt 1):103-12.
2001
Quinn CC, Begenisich T. "The influence of surface charges on quaternary ammonium block of shaker K+ channels." The Journal of membrane biology. 2001 182(3):233-43.
2001
Park K, Begenisich T, Melvin JE. "Protein kinase A activation phosphorylates the rat ClC-2 Cl- channel but does not change activity." The Journal of membrane biology. 2001 182(1):31-7.
2001
Thompson J, Begenisich T. "Affinity and location of an internal K+ ion binding site in shaker K channels." The Journal of general physiology. 2001 117(5):373-84.
2000
Thompson J, Begenisich T. "Interaction between quaternary ammonium ions in the pore of potassium channels. Evidence against an electrostatic repulsion mechanism." The Journal of general physiology. 2000 115(6):769-82.
2000
Thompson J, Begenisich T. "Electrostatic interaction between charybdotoxin and a tetrameric mutant of Shaker K(+) channels." Biophysical journal. 2000 78(5):2382-91.
1998
Stampe P, Arreola J, Pérez-Cornejo P, Begenisich T. "Nonindependent K+ movement through the pore in IRK1 potassium channels." The Journal of general physiology. 1998 112(4):475-84.
1998
Park K, Arreola J, Begenisich T, Melvin JE. "Comparison of voltage-activated Cl- channels in rat parotid acinar cells with ClC-2 in a mammalian expression system." The Journal of membrane biology. 1998 163(2):87-95.
1998
Perez-Cornejo P, Stampe P, Begenisich T. "Proton probing of the charybdotoxin binding site of Shaker K+ channels." The Journal of general physiology. 1998 111(3):441-50.
1998
Arreola J, Melvin JE, Begenisich T. "Differences in regulation of Ca(2+)-activated Cl- channels in colonic and parotid secretory cells." The American journal of physiology. 1998 274(1 Pt 1):C161-6.
1998
Begenisich T. "Determining ion channel permeation properties." Methods in enzymology. 1998 293:383-90.
1998
Stampe P, Begenisich T. "Unidirectional fluxes through ion channels expressed in Xenopus oocytes." Methods in enzymology. 1998 293:556-64.
1996
Arreola J, Melvin JE, Begenisich T. "Activation of calcium-dependent chloride channels in rat parotid acinar cells." The Journal of general physiology. 1996 108(1):35-47.
1996
Stampe P, Begenisich T. "Unidirectional K+ fluxes through recombinant Shaker potassium channels expressed in single Xenopus oocytes." The Journal of general physiology. 1996 107(4):449-57.
1996
Arreola J, Park K, Melvin JE, Begenisich T. "Three distinct chloride channels control anion movements in rat parotid acinar cells." The Journal of physiology. 1996 490 ( Pt 2):351-62.
1995
Arreola J, Melvin JE, Begenisich T. "Inhibition of Ca(2+)-dependent Cl- channels from secretory epithelial cells by low internal pH." The Journal of membrane biology. 1995 147(1):95-104.
1995
Arreola J, Melvin JE, Begenisich T. "Volume-activated chloride channels in rat parotid acinar cells." The Journal of physiology. 1995 484 ( Pt 3):677-87.
1995
Spires S, Begenisich T. "Voltage-independent gating transitions in squid axon potassium channels." Biophysical journal. 1995 68(2):491-500.
1994
Spires S, Begenisich T. "Modulation of potassium channel gating by external divalent cations." The Journal of general physiology. 1994 104(4):675-92.
1994
Pérez-Cornejo P, Begenisich T. "The multi-ion nature of the pore in Shaker K+ channels." Biophysical journal. 1994 66(6):1929-38.
1993
Nealey T, Spires S, Eatock RA, Begenisich T. "Potassium channels in squid neuron cell bodies: comparison to axonal channels." The Journal of membrane biology. 1993 132(1):13-25.
1993
Arreola J, Spires S, Begenisich T. "Na+ channels in cardiac and neuronal cells derived from a mouse embryonal carcinoma cell line." The Journal of physiology. 1993 472:289-303.
1992
Spires S, Begenisich T. "Chemical properties of the divalent cation binding site on potassium channels." The Journal of general physiology. 1992 100(2):181-93.
1992
Spires S, Begenisich T. "Modification of potassium channel kinetics by amino group reagents." The Journal of general physiology. 1992 99(1):109-29.
1992
Begenisich T. "Ion channel selectivity, permeation, and block." Methods in enzymology. 1992 207:92-100.
1991
Smith-Maxwell CJ, Eatock RA, Begenisich T. "Induction of K-channel expression in a neuroblastoma cell line." Journal of neurobiology. 1991 22(4):327-41.
1990
Spires S, Begenisich T. "Modification of potassium channel kinetics by histidine-specific reagents." The Journal of general physiology. 1990 96(4):757-75.
1989
Walsh KB, Begenisich TB, Kass RS. "Beta-adrenergic modulation of cardiac ion channels. Differential temperature sensitivity of potassium and calcium currents." The Journal of general physiology. 1989 93(5):841-54.
1989
Bennett PB, Kass R, Begenisich T. "Nonstationary fluctuation analysis of the delayed rectifier K channel in cardiac Purkinje fibers. Actions of norepinephrine on single-channel current." Biophysical journal. 1989 55(4):731-8.
1989
Spires S, Begenisich T. "Pharmacological and kinetic analysis of K channel gating currents." The Journal of general physiology. 1989 93(2):263-83.
1988
Walsh KB, Begenisich TB, Kass RS. "Beta-adrenergic modulation in the heart. Independent regulation of K and Ca channels." Pflügers Archiv : European journal of physiology. 1988 411(2):232-4.
1987
Smith-Maxwell C, Begenisich T. "Guanidinium analogues as probes of the squid axon sodium pore. Evidence for internal surface charges." The Journal of general physiology. 1987 90(3):361-74.
1987
Bennett PB, Begenisich TB. "Catecholamines modulate the delayed rectifying potassium current (IK) in guinea pig ventricular myocytes." Pflügers Archiv : European journal of physiology. 1987 410(1-2):217-9.
1986
Chabala LD, Morello RS, Busath D, Danko M, Smith-Maxwell CJ, Begenisich T. "Capture, transport, and maintenance of live squid (Loligo pealei) for electrophysiological studies." Pflügers Archiv : European journal of physiology. 1986 407(1):105-8.
1986
Bennett P, McKinney L, Begenisich T, Kass RS. "Adrenergic modulation of the delayed rectifier potassium channel in calf cardiac Purkinje fibers." Biophysical journal. 1986 49(4):839-48.
1986
Danko M, Smith-Maxwell C, McKinney L, Begenisich T. "Block of sodium channels by internal mono- and divalent guanidinium analogues. Modulation by sodium ion concentration." Biophysical journal. 1986 49(2):509-19.
1985
Bennett PB, McKinney LC, Kass RS, Begenisich T. "Delayed rectification in the calf cardiac Purkinje fiber. Evidence for multiple state kinetics." Biophysical journal. 1985 48(4):553-67.
1985
McKinney LC, Danko M, Smith CJ, Begenisich T. "Permeability of the squid giant axon to organic cations and small nonelectrolytes." The Journal of membrane biology. 1985 83(1-2):177-86.
1984
Morello RS, Begenisich T, Yeh JZ. "Determination of the active form of phenytoin." The Journal of pharmacology and experimental therapeutics. 1984 230(1):156-61.
1983
Begenisich T, Danko M. "Hydrogen ion block of the sodium pore in squid giant axons." The Journal of general physiology. 1983 82(5):599-618.
1982
Busath D, Begenisich T. "Unidirectional sodium and potassium fluxes through the sodium channel of squid giant axons." Biophysical journal. 1982 40(1):41-9.
1981
Begenisich T, Busath D. "Sodium flux ratio in voltage-clamped squid giant axons." The Journal of general physiology. 1981 77(5):489-502.
1980
Begenisich TB, Cahalan MD. "Sodium channel permeation in squid axons. I: Reversal potential experiments." The Journal of physiology. 1980 307:217-42.
1980
Begenisich TB, Cahalan MD. "Sodium channel permeation in squid axons. II: Non-independence and current-voltage relations." The Journal of physiology. 1980 307:243-57.
1980
Morello R, Begenisich T, Trzos W, Reed JK. "Interaction of nonylguanidine with the sodium channel." Biophysical journal. 1980 31(3):435-40.
1980
Begenisich T, De Weer P. "Potassium flux ratio in voltage-clamped squid giant axons." The Journal of general physiology. 1980 76(1):83-98.
1979
Begenisich T. "Conditioning hyperpolarization-induced delays in the potassium channels of myelinated nerve." Biophysical journal. 1979 27(2):257-65.
1977
Begenisich T, De Weer P. "Ionic interactions in the potassium channel of squid giant axons." Nature. 1977 269(5630):710-1.
1976
Cahalan M, Begenisich T. "Sodium channel selectivity. Dependence on internal permeant ion concentration." The Journal of general physiology. 1976 68(2):111-25.
1975
Goldman L, Hahin R, Begenisich T. "Letter: Sodium flux, action potential and temperature dependence." Nature. 1975 257(5526):516-7.
1975
Begenisich T, Stevens CF. "How many conductance states do potassium channels have?" Biophysical journal. 1975 15(8):843-6.
1975
Begenisich T. "Magnitude and location of surface charges on Myxicola giant axons." The Journal of general physiology. 1975 66(1):47-65.
1974
Begenisich T, Lynch C. "Effects of internal divalent cations on voltage-clamped squid axons." The Journal of general physiology. 1974 63(6):675-89.