Shirley Joseph, Ph.D.

Shirley Joseph, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 670
Rochester, NY 14642

Office: (585) 275-2579
Fax: (585) 273-2960

Journal Articles

Showing all 73 journal articles available.

2006 Jul 7
Joseph SA, Lynd-Balta E, O'Banion MK, Rappold PM, Daschner J, Allen A, Padowski J. "Enhanced cyclooxygenase-2 expression in olfactory-limbic forebrain following kainate-induced seizures." Neuroscience. 2006 Jul 7; 140(3):1051-65. Epub 2006 May 04.
2006 May 17
Rappold PM, Lynd-Balta E, Joseph SA. "P2X7 receptor immunoreactive profile confined to resting and activated microglia in the epileptic brain." Brain research. 2006 May 17; 1089(1):171-8. Epub 2006 Apr 25.
2005
Siddiqui AH, Joseph SA. "CA3 axonal sprouting in kainate-induced chronic epilepsy." Brain research. 2005 1066(1-2):129-46.
2004
Lynd-Balta E, Pilcher WH, Joseph SA. "AMPA receptor alterations precede mossy fiber sprouting in young children with temporal lobe epilepsy." Neuroscience. 2004 126(1):105-14.
1999 Sep 25
Tassorelli C, Joseph SA, Nappi G. "Reciprocal circuits involved in nitroglycerin-induced neuronal activation of autonomic regions and pain pathways: a double immunolabeling and tract-tracing study." Brain research. 1999 Sep 25; 842(2):294-310.
1998
Brouxhon,S. M.; Prasad,A. V.; Joseph,S. A.; Felten,D. L.; Bellinger,D. L.;. "Localization of corticotropin-releasing factor in primary and secondary lymphoid organs of the rat." Brain, Behavior, & Immunity. 1998; 12(2): 107-122.
1997
Blandini F, Joseph SA, Tassorelli C. "Systemic administration of ephedrine induces Fos protein expression in caudate putamen and subthalamic nucleus of rats." Functional neurology. 1997 12(5):293-6.
1996 Nov
Lynd-Balta E, Pilcher WH, Joseph SA. "Adrenocorticotropic hormone immunoreactivity in the hippocampal formation of temporal lobe epilepsy patients." Epilepsia. 1996 Nov; 37(11):1081-7.
1996 May
Lynd-Balta E, Pilcher WH, Joseph SA. "Distribution of AMPA receptor subunits in the hippocampal formation of temporal lobe epilepsy patients." Neuroscience. 1996 May; 72(1):15-29.
1996
Tassorelli C, Joseph SA. "Systemic nitroglycerin activates peptidergic and catecholaminergic pathways in rat brain." Peptides. 1996 17(3):443-9.
1996
Joseph SA, Tassorelli C, Prasad AV, Lynd-Balta E. "NF-kappa B transcription factor subunits in rat brain: colocalization of p65 and alpha-MSH." Peptides. 1996 17(4):655-64.
1995 Oct 9
Tassorelli C, Joseph SA. "NADPH-diaphorase activity and Fos expression in brain nuclei following nitroglycerin administration." Brain research. 1995 Oct 9; 695(1):37-44.
1995 Jun 5
Tassorelli C, Joseph SA. "Systemic nitroglycerin induces Fos immunoreactivity in brainstem and forebrain structures of the rat." Brain research. 1995 Jun 5; 682(1-2):167-81.
1994 Mar 28
Prasad AV, Pilcher WH, Joseph SA. "Nuclear factor-kappa B in rat brain: enhanced DNA-binding activity following convulsant-induced seizures." Neuroscience letters. 1994 Mar 28; 170(1):145-8.
1994 Jan
Sim LJ, Joseph SA. "Efferents of the opiocortin-containing region of the commissural nucleus tractus solitarius." Peptides. 1994 Jan; 15(1):169-74.
1993
Sim LJ, Joseph SA. "Dorsal raphe nucleus efferents: termination in peptidergic fields." Peptides. 1993 14(1):75-83.
1992 Oct 26
Liang CL, Kozlowski GP, Joseph SA, German DC. "ACTH1-39 inputs to mesocorticolimbic dopaminergic neurons: light and electron microscopic examination." Neuroscience letters. 1992 Oct 26; 146(1):79-83.
1992 May
Sim LJ, Joseph SA. "Efferent projections of the nucleus raphe magnus." Brain research bulletin. 1992 May; 28(5):679-82.
1992
Sim LJ, Joseph SA. "Serotonin and substance P afferents to parafascicular and central medial nuclei." Peptides. 1992 13(1):171-6.
1991
Sim LJ, Joseph SA. "Arcuate nucleus projections to brainstem regions which modulate nociception." Journal of chemical neuroanatomy. 1991 4(2):97-109.
1990
Joseph, S.A.; Pilcher, W.H.; Knigge, K.M.; Abood, L.G.; Michael, G.J. "Arginine vasopressin-anti-idiotypic immunostaining of human brain cells." Journal of Neuroendocrinology. 1990; 2: 659-665.
1989
Knigge KM, Piekut DT, Abood LG, Joseph SA, Michael GJ, Xin L, Berlove DJ. "Immunocytochemistry of receptors using anti-idiotypic antibodies." Methods in enzymology. 1989 178:212-21.
1989
Sim LJ, Joseph SA. "Opiocortin and catecholamine projections to raphe nuclei." Peptides. 1989 10(5):1019-25.
1988 Apr
Pilcher WH, Joseph SA, McDonald JV. "Immunocytochemical localization of pro-opiomelanocortin neurons in human brain areas subserving stimulation analgesia." Journal of neurosurgery. 1988 Apr; 68(4):621-9.
1988
Joseph SA, Michael GJ. "Efferent ACTH-IR opiocortin projections from nucleus tractus solitarius: a hypothalamic deafferentation study." Peptides. 1988 9(1):193-201.
1988
Harnish PP, Zuniga J, Northington FK, Melrose PA, Joseph SA, Kido DK, Knigge KM. "Effect of contrast media on beta-endorphin secretion. An in vitro study." Acta radiologica. 1988 29(6):741-3.
1987 Oct 6
Zuniga J, Joseph S, Knigge K. "Nitrous oxide analgesia: partial antagonism by naloxone and total reversal after periaqueductal gray lesions in the rat." European journal of pharmacology. 1987 Oct 6; 142(1):51-60.
1987 Sep 8
Zuniga JR, Joseph SA, Knigge KM. "The effects of nitrous oxide on the secretory activity of pro-opiomelanocortin peptides from basal hypothalamic cells attached to cytodex beads in a superfusion in vitro system." Brain research. 1987 Sep 8; 420(1):66-72.
1987 Sep 8
Zuniga JR, Joseph SA, Knigge KM. "The effects of nitrous oxide on the central endogenous pro-opiomelanocortin system in the rat." Brain research. 1987 Sep 8; 420(1):57-65.
1986
Zuniga,J. R.; Knigge,K. K.; Joseph,S. A.;. "Central beta-endorphin release and recovery after exposure to nitrous oxide in rats." Journal of Oral & Maxillofacial Surgery. 1986; 44(9): 714-718.
1986
Joseph SA, Piekut DT. "Dual immunostaining procedure demonstrating neurotransmitter and neuropeptide codistribution in the same brain section." The American journal of anatomy. 1986 175(2-3):331-42, 356-61.
1986
Pilcher WH, Joseph SA. "Differential sensitivity of hypothalamic and medullary opiocortin and tyrosine hydroxylase neurons to the neurotoxic effects of monosodium glutamate (MSG)." Peptides. 1986 7(5):783-9.
1986
Bennett-Clarke CA, Joseph SA. "Immunocytochemical localization of somatostatin in human brain." Peptides. 1986 7(5):877-84.
1986
Piekut DT, Joseph SA. "Co-existence of CRF and vasopressin immunoreactivity in parvocellular paraventricular neurons of rat hypothalamus." Peptides. 1986 7(5):891-8.
1985 Aug
Almqvist PM, Knigge KM, Kuenzig M, Joseph SA, Pilcher WH, Schwartz SI. "Pulmonary platelet trapping induced by beta-endorphin injection in the cerebrospinal fluid in dogs." Surgery. 1985 Aug; 98(2):344-9.
1985 Jan
Joseph SA, Pilcher WH, Knigge KM. "Anatomy of the corticotropin-releasing factor and opiomelanocortin systems of the brain." Federation proceedings. 1985 Jan; 44(1 Pt 1):100-7.
1985
Piekut DT, Joseph SA. "Relationship of CRF-immunostained cells and magnocellular neurons in the paraventricular nucleus of rat hypothalamus." Peptides. 1985 6(5):873-82.
1985
Knigge KM, Piekut DT, Joseph SA. "The alpha MSH-specific and arcuate pro-opiomelanocortin neuronal systems of the hypothalamus: observations on their connectivity and response to colchicine treatment." Psychopharmacology bulletin. 1985 21(3):472-5.
1984 May 7
Pilcher WH, Joseph SA. "Co-localization of CRF-ir perikarya and ACTH-ir fibers in rat brain." Brain research. 1984 May 7; 299(1):91-102.
1984 Feb
Knigge KM, Joseph SA. "Anatomy of the opioid-systems of the brain." The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. 1984 Feb; 11(1):14-23.
1983 Oct 3
Romagnano MA, Joseph SA. "Immunocytochemical localization of ACTH1-39 in the brainstem of the rat." Brain research. 1983 Oct 3; 276(1):1-16.
1983 Aug 8
Joseph SA, Pilcher WH, Bennett-Clarke C. "Immunocytochemical localization of ACTH perikarya in nucleus tractus solitarius: evidence for a second opiocortin neuronal system." Neuroscience letters. 1983 Aug 8; 38(3):221-5.
1983 Feb 21
Joseph SA, Knigge KM. "Corticotropin releasing factor: immunocytochemical localization in rat brain." Neuroscience letters. 1983 Feb 21; 35(2):135-41.
1982 May 13
Knigge KM, Joseph SA. "Relationship of the central ACTH-immunoreactive opiocortin system to the supraoptic and paraventricular nuclei of the hypothalamus of the rat." Brain research. 1982 May 13; 239(2):655-8.
1982 Mar 25
Romagnano MA, Chafel TL, Pilcher WH, Joseph SA. "The distribution of enkephalin in the mediobasal hypothalamus of the mouse brain: effects of neonatal administration of MSG." Brain research. 1982 Mar 25; 236(2):497-504.
1982 Feb 25
Romagnano MA, Pilcher WH, Bennett-Clarke C, Chafel TL, Joseph SA. "Distribution of somatostatin in the mouse brain: effects of neonatal MSG treatment." Brain research. 1982 Feb 25; 234(2):387-98.
1982 Jan 28
Sawchenko PE, Swanson LW, Joseph SA. "The distribution and cells of origin of ACTH(1-39)-stained varicosities in the paraventricular and supraoptic nuclei." Brain research. 1982 Jan 28; 232(2):365-74.
1982
Bennett-Clarke,C.; Joseph,S. A.;. "Immunocytochemical distribution of LHRH neurons and processes in the rat: hypothalamic and extrahypothalamic locations." Cell & Tissue Research. 1982; 221(3): 493-504.
1981 Jul 20
Knigge KM, Joseph SA, Nocton J. "Topography of the ACTH-immunoreactive neurons in the basal hypothalamus of the rat brain." Brain research. 1981 Jul 20; 216(2):333-41.
1981
Joseph,S. A.; Piekut,D. T.; Knigge,K. M.;. "Immunocytochemical localization of luteinizing hormone-releasing hormone (LHRH) in Vibratome-sectioned brain." Journal of Histochemistry & Cytochemistry. 1981; 29(2): 247-254.
1981
Knigge,K. M.; Joseph,S. A.;. "Relationship of the central ACTH-immunoreactive opiocortin system to the median eminence and the pituitary gland of the rat." Cell & Tissue Research. 1981; 215(2): 333-340.
1980 Aug
Joseph SA. "Immunoreactive adrenocorticotropin in rat brain: a neuroanatomical study using antiserum generated against synthetic ACTH." The American journal of anatomy. 1980 Aug; 158(4):533-48.
1980 Apr 28
Bennett-Clarke C, Romagnano MA, Joseph SA. "Distribution of somatostatin in the rat brain: telencephalon and diencephalon." Brain research. 1980 Apr 28; 188(2):473-86.
1980
Knigge, K.M.; Joseph S.A. "LHRH and anti-LHRH activity in ventricular cerebrospinal fluid of children with hydrocephalus". Physiologist. 1980; 23: 145.
1980
Joseph, S.A.; Vullo, C.; Dembs, N. "ACTH-like immunoreactivity in hypothalamic and extra-hypothalamic regions of the rat brain". Anatomical Record. 1980; .
1979
Joseph,S. A.; Sternberger,L. A.;. "The unlabeled antibody method. Contrasting color staining of beta-lipotropin and ACTH-associated hypothalamic peptides without antibody removal." Journal of Histochemistry & Cytochemistry. 1979; 27(11): 1430-1437.
1979
Sternberger,L. A.; Joseph,S. A.;. "The unlabeled antibody method. Contrasting color staining of paired pituitary hormones without antibody removal." Journal of Histochemistry & Cytochemistry. 1979; 27(11): 1424-1429.
1978 Jan
Sternberger LA, Petrali JP, Joseph SA, Meyer HG, Mills KR. "Specificity of the immunocytochemical luteinizing hormone-releasing hormone receptor reaction." Endocrinology. 1978 Jan; 102(1):63-73.
1978
Joseph,S. A.; Knigge,K. M.;. "The endocrine hypothalamus: recent anatomical studies." Research Publications - Association for Research in Nervous & Mental Disease. 1978; 56: 15-47.
1978
Knigge,K. M.; Joseph,S. A.; Hoffman,G. E.;. "Organization of LRF-and SRIF-neurons in the endocrine hypothalamus." Research Publications - Association for Research in Nervous & Mental Disease. 1978; 56: 49-67.
1976
Knigge, K.M.; Joseph, S.A.; Hoffman, G.; Morris, M.; Donofrio, R. "Role of Cerebrospinal Fluid in Neuroendocrine Processes". Excerpta Medica. 1976; 1: 111-116.
1975 Oct
McKelvy JF, Sheridan M, Joseph S, Phelps CH, Perrie S. "Biosynthesis of thyrotropin-releasing hormone in organ cultures of the guinea pig median eminence." Endocrinology. 1975 Oct; 97(4):908-18.
1974 Jun
Knigge KM, Joseph SA. "Thyrotrophin releasing factor (TRF) in cerebrospinal fluid of the 3rd ventricle of rat." Acta endocrinologica. 1974 Jun; 76(2):209-13.
1974 Mar
Joseph SA, Knigge KM. "Localization and content of TSH in median eminence of the hypothalamus." The American journal of physiology. 1974 Mar; 226(3):630-3.
1974 Feb
Ching M, Evans AB, Evans ES, Joseph S, Sorrentino S. "Pituitary thyrotroph function in hypothyroid rats." Acta endocrinologica. 1974 Feb; 75(2):221-32.
1974 Feb
Knigge KM, Schock SA, Silverman AJ, Ching MC, Scott DE, Zeman D, Krobish-Dudley G. "Role of the ventricular system in neuroendocrine processes: synthesis and distribution of thyrotropin releasing factor (TRF) in the hypothalamus and third ventricle." The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. 1974 Feb; 1(1):74-84.
1973 Oct
Joseph SA, Scott DE, Vaala SS, Knigge KM, Krobisch-Dudley G. "Localization and content of thyrotrophin releasing factor (TRE) in median eminence of the hypothalamus." Acta endocrinologica. 1973 Oct; 74(2):215-25.
1973
Knigge KM, Joseph SA, Silverman AJ, Vaala S. "Further observations on the structure and function of median eminence, with reference to the organization of RF-producing elements in the endocrine hypothalamus." Progress in brain research. 1973 39:7-20.
1972
Joseph SA, Knigge KM. "Neural regulation of TSH secretion: thyroxine feedback in the newborn." Neuroendocrinology. 1972 10(4):197-206.
1971
Knigge KM, Joseph SA. "Neural regulation of TSH secretion: sites of thyroxine feedback." Neuroendocrinology. 1971 8(5):273-88.
1969
Joseph SA, Knigge KM, Voloschin L. "Effects of isolation of the hypothalamo-pituitary unit in newborn guinea pigs." Neuroendocrinology. 1969 4(1):42-50.
1968
Joseph, S.A. and Knigge, K.M. "Effects of lesions in the ventro-medial nucleus of the hypothalamus in newborn and adult guinea pigs". Neuroendocrinology. 1968; 3: 309-331.
1968
Voloschin L, Joseph SA, Knigge KM. "Endocrine function in male rats following complete and partial isolations of the hypothalamo-pituitary unit." Neuroendocrinology. 1968 3(6):387-97.

Books

1997
Tassorelli, C.; Joseph, S.A.; Sandrini, G.; Costa, A.; Nappi, G. "Systemic nitroglycerine activates catecholamenergic, neuropeptidergic, and nitric oxide pathways in the rat brain". Headache Pathogenesis: Monamines, Neuropeptides Purines and Nitric Oxide. J. Olsen and L. Edvinsson. Philadelphia: Lippincott-Raven Publishers, 1997. 123-129
1991
Carpentar, P.J.; Joseph, S.A.. "Stress-induced analgesia as a model for investigating procedure-related distress in pediatric population". Advances in child health psychology. Johnson, J.H.; Johnson, S.B.. Gainesville: University of Florida Press, 1991. 51-54
1989
Knigge, K.M.; Piekut, D.T.; Abood, L.G.; Joseph, S.A.; Berlove, D.J.; Michael, G.J.. "Use of anti-idiotype antibodies in receptor immunocytochemistry". Antibodies, antigens, and molecular mimicry. Langone, John L.. San Diego: Academic Press, 1989. 212-221
1986
Hokfelt, T.; Melander, T.; Staines, W.; Wiesenfeld-Hallin, W.; Hulting, A.L.; Werner, S.; Eneroth, P.; Lindgren, J.A.; Samuelsson, B.; Patrono, C.; Rokaeus, A.; Rahrenkrug, J.; Joseph, S.A.; Fischer, J.. "Neuropeptides and their possible role as auxiliary messengers". Neuronal Control of Bodily Function-Basic and Clinical Aspects. Hendrie, H.C. and Frederickson, R.C.A. Boston, MA: Martinus-Nijhof, 1986. 61-89
1982
Knigge, K.M.; Joseph, S.A.;Milhorat, T.H.; Hammock, M.K.; MacDonald, J.V.. "Neuropeptides in ventricular cerebrospinal fluid of children with hydrocephalus". Frontiers of Hormone Research: Cerebrospinal Fluid (CSF) and Peptide Hormones. Rodríguez, E. M. ; Wimersma Greidanus, Tj. B. van.. New York: Karger, 1982. 179-188
1980
Knigge, K.M.; Hoffman, G.E.; Joseph, S.A.; Scott, D.E.; Sladek, C.D.; Sladek, J.R.. "Recent advances in structure and function of the endocrine hypotalamus". Handbook of the Hypothalamus. Morgane, P.J. and Panksepp, J.P. New York: DeKer, Inc., 1980. 63-164
1980
Knigge, K.M.; Bennette-Clarke, C.; Burchanowski, B.; Joseph, SA; Romagnano, MA. "Systems to the ventricles of the brain". The Endocrine Functions of the Brain. Motta, M.. New York: Raven Press, 1980. 195-206
1978
Joseph S.A.; Knigge K.M.. "Changes in hypothalamic content of LRF in animals immunized against melatonin". Current Studies of Hypothalamic Function. Lederis K.; Veale, W.L.. New York: S. Karger, 1978. 164-170
1975
Joseph S.A.; Sorrentino, S.; Sundberg, D.K.. "Releasing Hormones LRF and TRF in the cerebrospinal fluid". Brain-endocrine interaction II : The Ventricular System in Neuroendocrine Mecha. Knigge, K.M.. New York: S. Karger, 1975. 306-312
1975
Knigge K.M., M. Morris, D.E., Scott, S.A., Joseph, M. Notter, D. Schock, G. Krobish-Dudley. "Distribution of Hormones by Cerebrospinal Fluid". Fluid environment of the brain. Cseer, H.F.; Fencl, V.; Fenstermacher, J.D.. New York: Academic Press, 1975. 237-253
1971
Knigge, K.M.; Joseph, S.A.; Scott, D.E.; Jacobs, J.J.. "Observations on the architecture of the arcuatemedian eminence region after deafferntation with reference to the organization of the hypothalamic RF-producing elements.". The Neuroendocrinology of Human Reproduction. Mack, H.C.; Sherman, A.I.. Detroit, MI: C.C. Thomas, 1971. 6-22
1963
Knigge, K.M.; Joseph, S.A.. A stereotaxic atlas of the brain of the golden hamster, Mesocricetus auratus. Knigge, K.M.; Joseph, S.A.. Cincinnati: Dept. of Anatomy, Univ. of Cincinnati, 1963.