Photo not available

Peter C. Keng, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 704
Rochester, NY 14642

Journal Articles

Showing all 152 journal articles available.

2008 Jul 3
Gehen SC, Staversky RJ, Bambara RA, Keng PC, O'Reilly MA. "hSMG-1 and ATM sequentially and independently regulate the G1 checkpoint during oxidative stress." Oncogene.. 2008 Jul 3; 27(29):4065-74. Epub 2008 Mar 10.
2008
Zhang, H.; Hyrien, O.; Pandya, K.; Keng, PC.; and Chen, Y. "Tumor response kinetics after schedule-dependent Paclitaxel chemoradiation treatment for inoperable non-small cell lung cancer: a model for low-dose chemotherapy radiosensitization." J Thoracic Oncology. 2008; .
2008
Vitiello, PF.; Staversky, RJ.; Keng, PC.; and O'Reilly, MA. "PUMA inactivation protects against oxidative stress through p21/Bcl-XL inhibition of Bax death." Biochem. 2008; .
2008
Chen, Y.; Pandya, KJ.; Keng, PC.; Smudzin, T.; Anderson, J.; Qazi, R.; Smith, B.; Watson, TJ.; Johnston, DW.; Feins, RH. "Phase II study of one-cycle induction docetaxel/cisplatin with rhG-CSF and sensitizing docetaxel chemoradiation for stage III non-small cell lung cancer." J Thoracic Oncology. 2008; .
2008
Yee, M.; Vitiello, PF.; Keng, PC.; Palis, J.; Panoskaltsis-Mortari, A.; Blazar, BR.; Finkelstein, JN.; and O'Reilly, MA. "Identification of label-retaining Type II cells with limited ability to undergo transdifferentiation." Am J Physiol. 2008; .
2008
Sun W, Wang W, Kim J, Keng P, Yang S, Zhang H, Liu C, Okunieff P, Zhang L. "Anti-cancer effect of resveratrol is associated with induction of apoptosis via a mitochondrial pathway alignment." Advances in experimental medicine and biology. 2008 614:179-86.
2007 Jul
Ghosh A, Keng PC, Knauf PA. "Hypertonicity induced apoptosis in HL-60 cells in the presence of intracellular potassium." Apoptosis : an international journal on programmed cell death. 2007 Jul; 12(7):1281-8.
2007 Mar
Gehen SC, Vitiello PF, Bambara RA, Keng PC, O'Reilly MA. "Downregulation of PCNA potentiates p21-mediated growth inhibition in response to hyperoxia." American journal of physiology. Lung cellular and molecular physiology.. 2007 Mar; 292(3):L716-24. Epub 2006 Nov 03.
2007
Dertinger SD, Tsai Y, Nowak I, Hyrien O, Sun H, Bemis JC, Torous DK, Keng P, Palis J, Chen Y. "Reticulocyte and micronucleated reticulocyte responses to gamma irradiation: dose-response and time-course profiles measured by flow cytometry." Mutation research.. 2007 634(1-2):119-25. Epub 2007 Jul 05.
2007
Wang, W.; Yang, S., Su, Y.; Xiao, Z.; Wang, C.; Li, X.; Lin, L.; Fenton, BM.; Paoni, SF.; Ding, I.; Keng, P.; Okunieff, P.; and Zhang, L. "Enhanced anti-tumor effect of combined triptolide and ionizing radiation." Clin Cancer Res. 2007; .
2006 Aug 15
Staversky RJ, Vitiello PF, Gehen SC, Helt CE, Rahman A, Keng PC, O'Reilly MA. "p21(Cip1/Waf1/Sdi1) protects against hyperoxia by maintaining expression of Bcl-X(L)." Free radical biology & medicine.. 2006 Aug 15; 41(4):601-9. Epub 2006 May 23.
2006 May
Mao W, Iwai C, Keng PC, Vulapalli R, Liang CS. "Norepinephrine-induced oxidative stress causes PC-12 cell apoptosis by both endoplasmic reticulum stress and mitochondrial intrinsic pathway: inhibition of phosphatidylinositol 3-kinase survival pathway." American journal of physiology. Cell physiology.. 2006 May; 290(5):C1373-84. Epub 2005 Dec 07.
2006 Apr 28
Yao Z, Li P, Zhang Q, Schwarz EM, Keng P, Arbini A, Boyce BF, Xing L. "Tumor necrosis factor-alpha increases circulating osteoclast precursor numbers by promoting their proliferation and differentiation in the bone marrow through up-regulation of c-Fms expression." The Journal of biological chemistry.. 2006 Apr 28; 281(17):11846-55. Epub 2006 Feb 06.
2006 Feb 1
Chen MF, Keng PC, Shau H, Wu CT, Hu YC, Liao SK, Chen WC. "Inhibition of lung tumor growth and augmentation of radiosensitivity by decreasing peroxiredoxin I expression." International journal of radiation oncology, biology, physics.. 2006 Feb 1; 64(2):581-91.
2006 Jan
Tsai MH. Chen X. Chandramouli GV. Chen Y. Yan H. Zhao S. Keng P. Liber HL. Coleman CN. Mitchell JB. Chuang EY. "Transcriptional responses to ionizing radiation reveal that p53R2 protects against radiation-induced mutagenesis in human lymphoblastoid cells." Oncogene. 25(4):622-32, 2006 Jan 26.. 2006; 25(4): 622-32. Link
2006
Brandt, PD.; Helt, CE.; Keng, PC.; Bambara, RA. "The Rad9 protein enhances survival and promotes DNA repair following exposure to ionizing radiation." Biochemical & Biophysical Research Communications.. 2006; 347(1): 232-7. Link
2005 Sep
Lee YJ. Keng PC. "Studying the effects of actin cytoskeletal destabilization on cell cycle by cofilin overexpression." Molecular Biotechnology. 31(1):1-10, 2005 Sep.. 2005; 31(1): 1-10. Link
2005 Sep
Lee YJ. Sheu TJ. Keng PC. "Enhancement of radiosensitivity in H1299 cancer cells by actin-associated protein cofilin." Biochemical & Biophysical Research Communications. 335(2):286-91, 2005 Sep 23.. 2005; 335(2): 286-91. Link
2005 May
McCollum G. Keng PC. States JC. McCabe MJ Jr. "Arsenite delays progression through each cell cycle phase and induces apoptosis following G2/M arrest in U937 myeloid leukemia cells." Journal of Pharmacology & Experimental Therapeutics. 313(2):877-87, 2005 May.. 2005; 313(2): 877-87. Link
2005 Apr
Helt CE, Wang W, Keng PC, Bambara RA. "Evidence that DNA damage detection machinery participates in DNA repair." Cell cycle.. 2005 Apr; 4(4):529-32. Epub 2005 Apr 10.
2005 Feb
Mazzatti DJ, Lee YJ, Helt CE, O'Reilly MA, Keng PC. "p53 modulates radiation sensitivity independent of p21 transcriptional activation." American journal of clinical oncology.. 2005 Feb; 28(1):43-50.
2005 Jan 14
Helt CE, Cliby WA, Keng PC, Bambara RA, O'Reilly MA. "Ataxia telangiectasia mutated (ATM) and ATM and Rad3-related protein exhibit selective target specificities in response to different forms of DNA damage." The Journal of biological chemistry.. 2005 Jan 14; 280(2):1186-92. Epub 2004 Nov 08.
2005
Lee YJ. Mazzatti DJ. Yun Z. Keng PC. "Inhibition of invasiveness of human lung cancer cell line H1299 by over-expression of cofilin." Cell Biology International. 29(11):877-83, 2005 Nov.. 2005; 29(11). Link
2005
Chen MF. Keng PC. Lin PY. Yang CT. Liao SK. Chen WC. "Caffeic acid phenethyl ester decreases acute pneumonitis after irradiation in vitro and in vivo." BMC Cancer. 5:158, 2005. 2005; 5: 158-68. Link
2004 Jun
Chen MF, Wu CT, Chen YJ, Keng PC, Chen WC. "Cell killing and radiosensitization by caffeic acid phenethyl ester (CAPE) in lung cancer cells." Journal of radiation research. 2004 Jun; 45(2):253-60.
2004 May
Roper JM. Mazzatti DJ. Watkins RH. Maniscalco WM. Keng PC. O'Reilly MA. "In vivo exposure to hyperoxia induces DNA damage in a population of alveolar type II epithelial cells." American Journal of Physiology - Lung Cellular & Molecular Physiology. 286(5):L1045-54, 2004 May.. 2004; 286(5): L1045-54. Link
2004 Mar
Wang L. Hsu CL. Ni J. Wang PH. Yeh S. Keng P. Chang C. "Human checkpoint protein hRad9 functions as a negative coregulator to repress androgen receptor transactivation in prostate cancer cells." Molecular & Cellular Biology. 24(5):2202-13, 2004 Mar. 2004; 24(5): 2202-13. Link
2004 Mar
Helt CE. Staversky RJ. Lee YJ. Bambara RA. Keng PC. O'Reilly MA. "The Cdk and PCNA domains on p21Cip1 both function to inhibit G1/S progression during hyperoxia." American Journal of Physiology - Lung Cellular & Molecular Physiology. 286(3):L506-13, 2004 Mar.. 2004; 286(3): L506-13. Link
2004 Mar
Helt CE. Staversky RJ. Lee YJ. Bambara RA. Keng PC. O'Reilly MA. "The Cdk and PCNA domains on p21Cip1 both function to inhibit G1/S progression during hyperoxia." American Journal of Physiology - Lung Cellular & Molecular Physiology. 286(3):L506-13, 2004 Mar.. 2004; 286(3): L506-13. Link
2004 Feb
Abeysinghe HR. Pollock SJ. Guckert NL. Veyberman Y. Keng P. Halterman M. Federoff HJ. Rosenblatt JP. Wang N. "The role of the THY1 gene in human ovarian cancer suppression based on transfection studies." Cancer Genetics & Cytogenetics. 149(1):1-10, 2004 Feb.. 2004; 149(1): 1-10. Link
2004
Chen MF. Wu CT. Chen YJ. Keng PC. Chen WC. "Cell killing and radiosensitization by caffeic acid phenethyl ester (CAPE) in lung cancer cells." Journal of Radiation Research. 45(2):253-60, 2004 Jun. 2004; 45(2): 253-60. Link
2004
Mao W. Qin F. Iwai C. Vulapalli R. Keng PC. Liang CS. "Extracellular norepinephrine reduces neuronal uptake of norepinephrine by oxidative stress in PC12 cells." American Journal of Physiology - Heart & Circulatory Physiology.. 2004; 287(1): H29-39. Link
2003 Sep
Roper JM. Staversky RJ. Finkelstein JN. Keng PC. O'Reilly MA. "Identification and isolation of mouse type II cells on the basis of intrinsic expression of enhanced green fluorescent protein." American Journal of Physiology - Lung Cellular & Molecular Physiology.. 2003; 285(3): L691-700. Link
2003 Aug
Liu W, Chen Y, Wang W, Keng P, Finkelstein J, Hu D, Liang L, Guo M, Fenton B, Okunieff P, Ding I. "Combination of radiation and celebrex (celecoxib) reduce mammary and lung tumor growth." American journal of clinical oncology.. 2003 Aug; 26(4):S103-9.
2003 Jun
Abeysinghe HR. Cao Q. Xu J. Pollock S. Veyberman Y. Guckert NL. Keng P. Wang N. "THY1 expression is associated with tumor suppression of human ovarian cancer." Cancer Genetics & Cytogenetics.. 2003; 143(2): 125-32. Link
2003 Mar
Chen Y, Pandya K, Keng PC, Johnstone D, Li J, Lee YJ, Smudzin T, Okunieff P. "Phase I/II clinical study of pulsed paclitaxel radiosensitization for thoracic malignancy: a therapeutic approach on the basis of preclinical research of human cancer cell lines." Clinical cancer research : an official journal of the American Association for Cancer Research.. 2003 Mar; 9(3):969-75.
2003 Feb
Xing L. Carlson L. Story B. Tai Z. Keng P. Siebenlist U. Boyce BF. "Expression of either NF-kappaB p50 or p52 in osteoclast precursors is required for IL-1-induced bone resorption." Journal of Bone & Mineral Research. 18(2):260-9, 2003 Feb.. 2003; 18(2): 260-9. Link
2003 Feb
O'Reilly MA. Staversky RJ. Finkelstein JN. Keng PC. "Activation of the G2 cell cycle checkpoint enhances survival of epithelial cells exposed to hyperoxia." American Journal of Physiology - Lung Cellular & Molecular Physiology.. 2003; 284(2): L368-75. Link
2002 Oct
Rancourt RC, Hayes DD, Chess PR, Keng PC, O'Reilly MA. "Growth arrest in G1 protects against oxygen-induced DNA damage and cell death." Journal of cellular physiology.. 2002 Oct; 193(1):26-36.
2002 Sep
Baev D. Li XS. Dong J. Keng P. Edgerton M. "Human salivary histatin 5 causes disordered volume regulation and cell cycle arrest in Candida albicans." Infection & Immunity.. 2002; 70(9): 4777-84. Link
2001 Oct
Matsui Y, Tsuchida Y, Keng PC. "Effects of p53 mutations on cellular sensitivity to ionizing radiation." American journal of clinical oncology.. 2001 Oct; 24(5):486-90.
2001 Sep
Cao Q. Abeysinghe H. Chow O. Xu J. Kaung H. Fong C. Keng P. Insel RA. Lee WM. Barrett JC. Wang N. "Suppression of tumorigenicity in human ovarian carcinoma cell line SKOV-3 by microcell-mediated transfer of chromosome 11." Cancer Genetics & Cytogenetics.. 2001; 129(2): 131-7. Link
2001 Jun
O'Reilly MA. Staversky RJ. Watkins RH. Reed CK. de Mesy Jensen KL. Finkelstein JN. Keng PC. "The cyclin-dependent kinase inhibitor p21 protects the lung from oxidative stress." American Journal of Respiratory Cell & Molecular Biology.. 2001; 24(6): 703-10. Link
2001 Apr
Rancourt RC. Keng PC. Helt CE. O'Reilly MA. "The role of p21(CIP1/WAF1) in growth of epithelial cells exposed to hyperoxia." American Journal of Physiology - Lung Cellular & Molecular Physiology.. 2001; 280(4): L617-26. Link
2000 Sep
Chen YG. Mantalaris A. Bourne P. Keng P. Wu JH. "Expression of mPer1 and mPer2, two mammalian clock genes, in murine bone marrow." Biochemical & Biophysical Research Communications.. 2000; 276(2): 724-8. Link
2000 Mar
O'Reilly MA. Staversky RJ. Watkins RH. Maniscalco WM. Keng PC. "p53-independent induction of GADD45 and GADD153 in mouse lungs exposed to hyperoxia." American Journal of Physiology - Lung Cellular & Molecular Physiology.. 2000; 278(3): L552-9. Link
2000 Mar
Wheeler KT, Wang LM, Wallen CA, Childers SR, Cline JM, Keng PC, Mach RH. "Sigma-2 receptors as a biomarker of proliferation in solid tumours." British journal of cancer.. 2000 Mar; 82(6):1223-32.
2000 Feb
Lee J. Moran JP. Fenton BM. Koch CJ. Frelinger JG. Keng PC. Lord EM. "Alteration of tumour response to radiation by interleukin-2 gene transfer." British Journal of Cancer. 82(4):937-44, 2000 Feb.. 2000; 82(4): 937-44. Link
1999 Nov
Al-Nabulsi I, Mach RH, Wang LM, Wallen CA, Keng PC, Sten K, Childers SR, Wheeler KT. "Effect of ploidy, recruitment, environmental factors, and tamoxifen treatment on the expression of sigma-2 receptors in proliferating and quiescent tumour cells." British journal of cancer.. 1999 Nov; 81(6):925-33.
1999 Mar
Georgakoudi I, Keng PC, Foster TH. "Hypoxia significantly reduces aminolaevulinic acid-induced protoporphyrin IX synthesis in EMT6 cells." British journal of cancer.. 1999 Mar; 79(9-10):1372-7.
1999
Rancourt RC, Staversky RJ, Keng PC, O'Reilly MA. "Hyperoxia inhibits proliferation of Mv1Lu epithelial cells independent of TGF-beta signaling." The American journal of physiology.. 1999 277(6 Pt 1):L1172-8.
1998 Nov
de Toledo SM. Azzam EI. Keng P. Laffrenier S. Little JB. "Regulation by ionizing radiation of CDC2, cyclin A, cyclin B, thymidine kinase, topoisomerase IIalpha, and RAD51 expression in normal human diploid fibroblasts is dependent on p53/p21Waf1." Cell Growth & Differentiation.. 1998; 9(11): 887-96. Link
1998 Jun
Tsai MA, Waugh RE, Keng PC. "Passive mechanical behavior of human neutrophils: effects of colchicine and paclitaxel." Biophysical journal.. 1998 Jun; 74(6):3282-91.
1998 May 1
Nagasawa H, Keng P, Maki C, Yu Y, Little JB. "Absence of a radiation-induced first-cycle G1-S arrest in p53+ human tumor cells synchronized by mitotic selection." Cancer research.. 1998 May 1; 58(9):2036-41.
1998
Mantalaris A, Keng P, Bourne P, Chang AY, Wu JH. "Engineering a human bone marrow model: a case study on ex vivo erythropoiesis." Biotechnology progress.. 1998 14(1):126-33.
1998
Keng PC, Siemann DW. "Measurement of proliferation activities in human tumor models: a comparison of flow cytometric methods." Radiation oncology investigations. 1998 6(3):120-7.
1997 Aug
Wenz F. Yu Y. Nagasawa H. Imrich AC. Keng P. Little JB. "Lack of uncoupling of S phase and mitosis after irradiation in p53- human lymphoblast cell lines." Radiation Research. 148(2):129-34, 1997 Aug.. 1997; 148(2): 129-34. Link
1997 Jun
Powlin SS. Keng PC. Miller RK. "Toxicity of cadmium in human trophoblast cells (JAr choriocarcinoma): role of calmodulin and the calmodulin inhibitor, zaldaride maleate." Toxicology & Applied Pharmacology. 144(2):C, 1997 Jun. UI: Toxicology & Applied Pharmacology.. 1997; 144(2): 225-34. Link
1996 Jun
Rowley PT, Keng PC, Kosciolek BA. "The effect of bcr-abl antisense oligonucleotide on DNA synthesis and apoptosis in K562 chronic myeloid leukemia cells." Leukemia research.. 1996 Jun; 20(6):473-80.
1996 Apr
Tsai MA, Waugh RE, Keng PC. "Cell cycle-dependence of HL-60 cell deformability." Biophysical journal.. 1996 Apr; 70(4):2023-9.
1996
Tsai MA, Waugh RE, Keng PC. "Changes in HL-60 cell deformability during differentiation induced by DMSO." Biorheology. 1996 33(1):1-15.
1996
Masunaga S, Keng PC. "Effect of caffeine on gamma-ray induced G2 arrest in well-synchronized Chinese hamster ovary cells in vitro." Radiation medicine. 1996 14(6):309-13.
1995 May 12
Little JB, Nagasawa H, Keng PC, Yu Y, Li CY. "Absence of radiation-induced G1 arrest in two closely related human lymphoblast cell lines that differ in p53 status." The Journal of biological chemistry.. 1995 May 12; 270(19):11033-6.
1995 Feb 1
Keng PC, Phipps R, Penney DP. "In vitro radiation sensitivity of mouse lung fibroblasts isolated by flow cytometry." International journal of radiation oncology, biology, physics.. 1995 Feb 1; 31(3):519-23.
1994 Oct
Nagasawa H, Keng P, Harley R, Dahlberg W, Little JB. "Relationship between gamma-ray-induced G2/M delay and cellular radiosensitivity." International journal of radiation biology.. 1994 Oct; 66(4):373-9.
1994 Aug
Liesveld JL, Keng PC, Rowe JM, DiPersio JF, Abboud CN. "Effects of GM-CSF on Ki67 expression and cell cycle traverse in acute myelogenous leukemia specimens and cell lines." Leukemia research.. 1994 Aug; 18(8):609-16.
1994
Grota LJ, Reiter RJ, Keng P, Michaelson S. "Electric field exposure alters serum melatonin but not pineal melatonin synthesis in male rats." Bioelectromagnetics. 1994 15(5):427-37.
1993 Oct 20
McDonald S, Chang AY, Rubin P, Wallenberg J, Kim IS, Sobel S, Smith J, Keng P, Muhs A. "Combined Betaseron R (recombinant human interferon beta) and radiation for inoperable non-small cell lung cancer." International journal of radiation oncology, biology, physics.. 1993 Oct 20; 27(3):613-9.
1993 Sep
Chen DS. Law C. Keng P. "Reduction of radiation cytotoxicity by human apurinic endonuclease in a radiation-sensitive Escherichia coli mutant." Radiation Research. 135(3):405-10, 1993 Sep.. 1993; 135(3): 405-10. Link
1993 Sep
Chen DS, Law C, Keng P. "Reduction of radiation cytotoxicity by human apurinic endonuclease in a radiation-sensitive Escherichia coli mutant." Radiation research.. 1993 Sep; 135(3):405-10.
1993 Aug
Zhu W, Kriajevskaia M, Keng PC, Chou WG. "A "trans-acting" factor for activation of transcription is defective in the xrs-5 mutant of the Chinese hamster ovary cell line." Mutation research.. 1993 Aug; 294(2):101-8.
1993
Whartenby KA. Insel RA. Freeman SM. Keng P. Abraham GN. "Oncogene elements within an endogenous retrovirus." Acta Virologica. 37(2-3):113-22, 1993 Apr-Jun. 1993; 37(2-3): 113-22. Link
1993
Whartenby KA, Insel RA, Freeman SM, Keng P, Abraham GN. "Oncogene elements within an endogenous retrovirus." Acta virologica. 1993 37(2-3):113-22.
1992 Sep
Zhu W, Keng PC, Chou WG. "Differential gene expression in wild-type and X-ray-sensitive mutants of Chinese hamster ovary cell lines." Mutation research.. 1992 Sep; 274(3):237-45.
1992 Aug
Derdak S, Penney DP, Keng P, Felch ME, Brown D, Phipps RP. "Differential collagen and fibronectin production by Thy 1+ and Thy 1- lung fibroblast subpopulations." The American journal of physiology.. 1992 Aug; 263(2 Pt 1):L283-90.
1992 Jun
Chapuis JC, Keng PC, Siemann DW. "Activity of etoposide (VP-16) and teniposide (VM-26) in exponential and plateau phase human tumor cell cultures." Anti-cancer drugs. 1992 Jun; 3(3):245-52.
1992 May 15
Nasir A, Reynolds SD, Keng PC, Angerer LM, Angerer RC. "Centrifugal elutriation of large fragile cells: isolation of RNA from fixed embryonic blastomeres." Analytical biochemistry.. 1992 May 15; 203(1):22-6.
1992 Mar
Penney DP, Keng PC, Derdak S, Phipps RP. "Morphologic and functional characteristics of subpopulations of murine lung fibroblasts grown in vitro." The Anatomical record. 1992 Mar; 232(3):432-43.
1992
Felch ME, Willis RA, Penney DP, Keng PC, Phipps RP. "Expression of alpha 6 beta 1 integrin, the laminin receptor, on subsets of normal murine lung fibroblasts and its upregulation by the inflammatory cytokines IFN-gamma and TNF-alpha." Regional immunology. 1992 4(6):363-70.
1991 Mar
Constine LS, Harwell S, Keng P, Lee F, Rubin P, Siemann D. "Interleukin 1 alpha stimulates hemopoiesis but not tumor cell proliferation and protects mice from lethal total body irradiation." International journal of radiation oncology, biology, physics.. 1991 Mar; 20(3):447-56.
1991 Mar
Brennan JK, Lee KS, Frazel MA, Keng PC, Young DA. "Interactions of dimethyl sulfoxide and granulocyte-macrophage colony-stimulating factor on the cell cycle kinetics and phosphoproteins of G1-enriched HL-60 cells: evidence of early effects on lamin B phosphorylation." Journal of cellular physiology.. 1991 Mar; 146(3):425-34.
1991 Feb
Chapuis JC, Keng PC, Siemann DW. "Activity of etoposide (VP-16) in human tumor cells under different growth conditions." International journal of radiation oncology, biology, physics.. 1991 Feb; 20(2):373-5.
1990 Sep
Knuechel R, Keng P, Hofstaedter F, Langmuir V, Sutherland RM, Penney DP. "Differentiation patterns in two- and three-dimensional culture systems of human squamous carcinoma cell lines." The American journal of pathology.. 1990 Sep; 137(3):725-36.
1990 Aug
Phipps RP, Baecher C, Frelinger JG, Penney DP, Keng P, Brown D. "Differential expression of interleukin 1 alpha by Thy-1+ and Thy-1- lung fibroblast subpopulations: enhancement of interleukin 1 alpha production by tumor necrosis factor-alpha." European journal of immunology.. 1990 Aug; 20(8):1723-7.
1990 May
Keng PC, Allalunis-Turner J, Siemann DW. "Evaluation of cell subpopulations isolated from human tumor xenografts by centrifugal elutriation." International journal of radiation oncology, biology, physics.. 1990 May; 18(5):1061-7.
1990 Mar
Loeffler DA. Keng PC. Baggs RB. Lord EM. "Lymphocytic infiltration and cytotoxicity under hypoxic conditions in the EMT6 mouse mammary tumor." International Journal of Cancer.. 1990; 45(3): 462-7. Link
1990 Feb 7
Wilson RE, Keng PC, Sutherland RM. "Erratum: Drug resistance in Chinese hamster ovary cells during recovery from severe hypoxia." Journal of the National Cancer Institute.. 1990 Feb 7; 82(3):239.
1990 Jan
Wilson RE, Keng PC, Sutherland RM. "Changes in growth characteristics and macromolecular synthesis on recovery from severe hypoxia." British journal of cancer.. 1990 Jan; 61(1):14-21.
1990
Knüchel R, Hofstaedter F, Sutherland RM, Keng PC. "[Proliferation-associated antigens PCNA and Ki-67 in two- and three-dimensional experimental systems of human squamous epithelial carcinomas]." Verhandlungen der Deutschen Gesellschaft für Pathologie. 1990 74:275-8.
1990
Phipps RP, Penney DP, Keng P, Silvera M, Harkins S, Derdak S. "Immune functions of subpopulations of lung fibroblasts." Immunologic research. 1990 9(4):275-86.
1989 Dec
Domurat FM. Keng P. Mock DJ. Roberts NJ Jr. "Early identification and retrieval or deletion of human lymphocyte subpopulations responding to influenza virus or respiratory syncytial virus challenge." Cell Biophysics. 15(3):173-88, 1989 Dec. 1989; 15(3): 173-88. Link
1989 Aug 16
Wilson RE, Keng PC, Sutherland RM. "Drug resistance in Chinese hamster ovary cells during recovery from severe hypoxia." Journal of the National Cancer Institute.. 1989 Aug 16; 81(16):1235-40.
1989 Jul
Phipps RP. Penney DP. Keng P. Quill H. Paxhia A. Derdak S. Felch ME. "Characterization of two major populations of lung fibroblasts: distinguishing morphology and discordant display of Thy 1 and class II MHC." American Journal of Respiratory Cell & Molecular Biology.. 1989; 1(1): 65-74. Link
1989 Apr 4
Liu YC, Marraccino RL, Keng PC, Bambara RA, Lord EM, Chou WG, Zain SB. "Requirement for proliferating cell nuclear antigen expression during stages of the Chinese hamster ovary cell cycle." Biochemistry.. 1989 Apr 4; 28(7):2967-74.
1989 Mar
Wilson KM, Keng PC. "Radiation-induced DNA damage and repair in quiescent and proliferating human tumor cells in vitro." International journal of radiation biology.. 1989 Mar; 55(3):385-95.
1989
Domurat FM, Keng P, Mock DJ, Roberts NJ. "Early identification and retrieval or deletion of human lymphocyte subpopulations responding to influenza virus or respiratory syncytial virus challenge." Cell biophysics. 1989 15(3):173-88.
1988 Oct 15
Gringeri A, Keng PC, Borch RF. "Diethyldithiocarbamate inhibition of murine bone marrow toxicity caused by cis-diamminedichloroplatinum(II) or diammine-(1,1-cyclobutanedicarboxylato)platinum(II)." Cancer research.. 1988 Oct 15; 48(20):5708-12.
1988 Sep
Siemann DW, Keng PC. "Characterization of radiation resistant hypoxic cell subpopulations in KHT sarcomas. (II). Cell sorting." British journal of cancer.. 1988 Sep; 58(3):296-300.
1988 Jul 1
Lee FY, Siemann DW, Allalunis-Turner MJ, Keng PC. "Glutathione contents in human and rodent tumor cells in various phases of the cell cycle." Cancer research.. 1988 Jul 1; 48(13):3661-5.
1988 Jun 25
Wingrove TG, Watt R, Keng P, Macara IG. "Stabilization of myc proto-oncogene proteins during Friend murine erythroleukemia cell differentiation." The Journal of biological chemistry.. 1988 Jun 25; 263(18):8918-24.
1988 Jun
West CM, Keng PC, Sutherland RM. "Growth phase related variation in the radiation sensitivity of human colon adenocarcinoma cells." International journal of radiation oncology, biology, physics.. 1988 Jun; 14(6):1213-9.
1988 Mar
Wu DZ, Keng P. "Effects of bleomycins on synchronized cells by centrifugal elutriation." Zhongguo yao li xue bao = Acta pharmacologica Sinica. 1988 Mar; 9(2):170-4.
1988
Keng, P.C.,. "Analysis of human tumor cell kinetics using anti BrdUrd antibody and flow cytometry". Proceedings of the Third Symposium on Recent Advances in Biological and Medical Sciences, Academia Sinica. 1988; 18: 32-43. Link
1988
Siemann DW, Keng PC. "Responses of tumor cell subpopulations to single modality and combined modality therapies." NCI monographs : a publication of the National Cancer Institute. 1988 (6):101-5.
1988
White TE, Saltzman RA, Di Sant'Agnese PA, Keng PC, Sutherland RM, Miller RK. "Human choriocarcinoma (JAr) cells grown as multicellular spheroids." Placenta. 1988 9(6):583-98.
1988
Palis J, King B, Keng P. "Separation of spontaneously differentiating and cell cycle-specific populations of HL-60 cells." Leukemia research.. 1988 12(4):339-44.
1987 Nov
Loeffler DA, Keng PC, Wilson KM, Lord EM. "Comparison of fluorescence intensity of Hoechst 33342-stained EMT6 tumour cells and tumour-infiltrating host cells." British journal of cancer.. 1987 Nov; 56(5):571-6.
1987 Sep
Ng CE, Keng PC, Sutherland RM. "Characterization of radiation sensitivity of human squamous carcinoma A431 cells." British journal of cancer.. 1987 Sep; 56(3):301-7.
1987 Aug 15
Chang AY, Keng PC. "Potentiation of radiation cytotoxicity by recombinant interferons, a phenomenon associated with increased blockage at the G2-M phase of the cell cycle." Cancer research.. 1987 Aug 15; 47(16):4338-41.
1987 Aug
Brennan JK, Lee KS, Abboud CN, Erickson-Miller CL, Keng PC. "Interactions of dimethyl sulfoxide and granulocyte-macrophage colony-stimulating factors on the growth and maturation of HL-60 cells." Journal of cellular physiology.. 1987 Aug; 132(2):246-54.
1987 Feb
Mock DJ. Domurat F. Roberts NJ Jr. Walsh EE. Licht MR. Keng P. "Macrophages are required for influenza virus infection of human lymphocytes." Journal of Clinical Investigation. 79(2):620-4, 1987 Feb.. 1987; 79(2): 620-4. Link
1987 Feb
West CM, Keng PC, Siemann DW, Sutherland RM. "A human colon adenocarcinoma xenograft--radiation response, cellular composition, and tumor disaggregation." Journal of the National Cancer Institute.. 1987 Feb; 78(2):371-6.
1987 Feb
Mock DJ, Domurat F, Roberts NJ, Walsh EE, Licht MR, Keng P. "Macrophages are required for influenza virus infection of human lymphocytes." The Journal of clinical investigation.. 1987 Feb; 79(2):620-4.
1987 Jan
Siemann DW, Keng PC. "Characterization of radiation resistant hypoxic cell subpopulations in KHT sarcomas. (I). Centrifugal elutriation." British journal of cancer.. 1987 Jan; 55(1):33-6.
1987
Marraccino RL, Wahl AF, Keng PC, Lord EM, Bambara RA. "Cell cycle dependent activities of DNA polymerases alpha and delta in Chinese hamster ovary cells." Biochemistry.. 1987 26(24):7864-70.
1987
Lett JT. Keng PC. Bergtold DS. Howard J. "Effects of heavy ions on rabbit tissues: induction of DNA strand breaks in retinal photoreceptor cells by high doses of radiation." Radiation & Environmental Biophysics.. 1987; 26(1): 23-36. Link
1986 Sep
Ng CE. Keng PC. Sutherland RM. "Density distributions of human squamous carcinoma cells: influence of growth conditions, proliferative status and DNA content." International Journal of Cancer.. 1986; 38(3): 413-8. Link
1986 Sep
Keng PC. "Use of flow cytometry in the measurement of cell mitotic cycle." International journal of cell cloning. 1986 Sep; 4(5):295-311.
1986 Jul 1
Scott DW, Livnat D, Pennell CA, Keng P. "Lymphoma models for B cell activation and tolerance. III. Cell cycle dependence for negative signalling of WEHI-231 B lymphoma cells by anti-mu." The Journal of experimental medicine.. 1986 Jul 1; 164(1):156-64.
1986 Jul
Siemann DW, Keng PC. "Cell cycle specific toxicity of the Hoechst 33342 stain in untreated or irradiated murine tumor cells." Cancer research.. 1986 Jul; 46(7):3556-9.
1986 Jul
Luk CK, Keng PC, Sutherland RM. "Radiation response of proliferating and quiescent subpopulations isolated from multicellular spheroids." British journal of cancer.. 1986 Jul; 54(1):25-32.
1986 Jun
Bodenner DL, Dedon PC, Keng PC, Borch RF. "Effect of diethyldithiocarbamate on cis-diamminedichloroplatinum(II)-induced cytotoxicity, DNA cross-linking, and gamma-glutamyl transpeptidase inhibition." Cancer research.. 1986 Jun; 46(6):2745-50.
1986 Jun
Bodenner DL, Dedon PC, Keng PC, Katz JC, Borch RF. "Selective protection against cis-diamminedichloroplatinum(II)-induced toxicity in kidney, gut, and bone marrow by diethyldithiocarbamate." Cancer research.. 1986 Jun; 46(6):2751-5.
1986 Feb
Brosing JW, Keng PC, Mulcahy RT. "Survival characteristics of normal differentiated rat thyroid cells maintained in vitro." Radiation research.. 1986 Feb; 105(2):138-46.
1986
Lett JT, Bertold DS, Keng PC. "Effects of LET infinity on the fate of DNA damage induced in rabbit sensory cells in situ: fundamental aspects." Basic life sciences. 1986 38:139-50.
1985 Jun
Scott DW, Tuttle J, Livnat D, Haynes W, Cogswell JP, Keng P. "Lymphoma models for B-cell activation and tolerance. II. Growth inhibition by anti-mu of WEHI-231 and the selection and properties of resistant mutants." Cellular immunology.. 1985 Jun; 93(1):124-31.
1985 Mar
Luk CK, Keng PC, Sutherland RM. "Regrowth and radiation sensitivity of quiescent cells isolated from EMT6/Ro-fed plateau monolayers." Cancer research.. 1985 Mar; 45(3):1020-5.
1985 Jan
Siemann DW, Maddison K, Wolf K, Hill SA, Keng PC. "In vivo interaction between radiation and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea in the absence or presence of misonidazole in mice." Cancer research.. 1985 Jan; 45(1):198-202.
1985
Wu DZ, Zhang YQ, Keng P, Sutherland RM, Lasagna L. "The interaction between bleomycin and radiation on cell survival and DNA damage in mammalian cell cultures." International journal of radiation oncology, biology, physics.. 1985 11(12):2125-31.
1984 Oct
Keng PC, Rubin P, Constine LS, Frantz C, Nakissa N, Gregory P. "Characterization of the biophysical properties of human tumor and bone marrow cells as a preliminary step to the use of centrifugal elutriation in autologous bone marrow transplantation." International journal of radiation oncology, biology, physics.. 1984 Oct; 10(10):1913-22.
1984 Oct
Keng PC, Siemann DW, Wheeler KT. "Comparison of tumour age response to radiation for cells derived from tissue culture or solid tumours." British journal of cancer.. 1984 Oct; 50(4):519-26.
1984 Sep
Siemann DW, Keng PC. "In situ radiation response and oxygen enhancement ratio of KHT sarcoma cells in various phases of the cell cycle." The British journal of radiology. 1984 Sep; 57(682):823-7.
1984 Sep
Hill SA, Keng PC, Siemann DW. "Survival in subpopulations of cells derived from solid KHT sarcomas by centrifugal elutriation following treatment with CCNU and MISO." International journal of radiation oncology, biology, physics.. 1984 Sep; 10(9):1615-8.
1984 Sep
Hill SA, Bauer KD, Keng PC, Siemann DW. "The effect in the KHT sarcoma of CCNU and MISO on cell cycle progression evaluated by flow-cytometry." International journal of radiation oncology, biology, physics.. 1984 Sep; 10(9):1619-22.
1984 Mar 30
Lord EM, Keng PC. "Methods for using centrifugal elutriation to separate malignant and lymphoid cell populations." Journal of immunological methods.. 1984 Mar 30; 68(1-2):147-55.
1984
Lett JT, Bergtold DS, Cox AB, Keng PC, Okayasu R. "Further evidence that the survival of irradiated mammalian cells is controlled by temporal processes." The British journal of cancer. Supplement. 1984 6:163-8.
1983 Mar
Keng PC. Bergtold DS. Lett JT. "Effects of heavy ions on rabbit tissues: analysis of low levels of DNA damage in retinal photoreceptor cells." International Journal of Radiation Biology & Related Studies in Physics, Chemistry & Medicine.. 1983; 43(3): 219-29. Link
1983
Chang AY, Keng PC. "Inhibition of cell growth in synchronous human hypernephroma cells by recombinant interferon alpha-D and irradiation." Journal of interferon research. 1983 3(4):379-85.
1982 Oct
Cox AB. Keng PC. Lee AC. Lett JT. "Effects of heavy ions on rabbit tissues: damage to the forebrain." International Journal of Radiation Biology & Related Studies in Physics, Chemistry & Medicine.. 1982; 42(4): 355-67. Link
1982 Feb
Keng PC. Lee AC. Cox AB. Bergtold DS. Lett JT. "Effects of heavy ions on rabbit tissues: cataractogenesis." International Journal of Radiation Biology & Related Studies in Physics, Chemistry & Medicine.. 1982; 41(2): 127-37. Link
1982 Jan
Bauer KD, Keng PC, Sutherland RM. "Isolation of quiescent cells from multicellular tumor spheroids using centrifugal elutriation." Cancer research.. 1982 Jan; 42(1):72-8.
1982
Sutherland RM, Keng P, Conroy PJ, McDermott D, Bareham BJ, Passalacqua W. "In vitro hypoxic cytotoxicity of nitroimidazoles: uptake and cell cycle phase specificity." International journal of radiation oncology, biology, physics.. 1982 8(3-4):745-8.
1981 Dec
Cox AB. Keng PC. Glass NL. Lett JT. "Effects of heavy ions on rabbit tissues: alopecia." International Journal of Radiation Biology & Related Studies in Physics, Chemistry & Medicine.. 1981; 40(6): 645-57. Link
1981 Oct
Rubin P, Wheeler KT, Keng PC, Gregory PK, Croizat H. "The separation of a mixture of bone marrow stem cells from tumor cells: an essential step for autologous bone marrow transplantation." International journal of radiation oncology, biology, physics.. 1981 Oct; 7(10):1405-11.
1981 Jul
Keng PC, Wheeler KT, Siemann DW, Lord EM. "Direct synchronization of cells from solid tumors by centrifugal elutriation." Experimental cell research.. 1981 Jul; 134(1):15-22.
1981 Jul
Siemann DW, Lord EM, Keng PC, Wheeler KT. "Cell subpopulations dispersed from solid tumours and separated by centrifugal elutriation." British journal of cancer.. 1981 Jul; 44(1):100-8.
1981 Jun
Keng PC. Lett JT. "Effects of heavy ions on rabbit tissues: loss of electroretinogram and DNA repair in retinal photoreceptor cells." International Journal of Radiation Biology & Related Studies in Physics, Chemistry & Medicine.. 1981; 39(6): 655-64. Link
1981 Mar
Keng PC, Li CK, Wheeler KT. "Characterization of the separation properties of the Beckman elutriator system." Cell biophysics. 1981 Mar; 3(1):41-56.
1980 Sep
Keng PC, Li CK, Wheeler KT. "Synchronization of 9L rat brain tumor cells by centrifugal elutriation." Cell biophysics. 1980 Sep; 2(3):191-206.
1980 Sep
Keng PC, Wheeler KT. "Radiation response of synchronized 9L rat brain tumor cells separated by centrifugal elutriation." Radiation research.. 1980 Sep; 83(3):633-43.
1980
Lett JT. Cox AB. Keng PC. Lee AC. Su CM. Bergtold DS. "Late degeneration in rabbit tissues after irradiation by heavy ions." Life Sciences & Space Research.. 1980; 18: 131-42. Link
1978
Lett, J.T., Keng, P.C. and Sun, C.,. "DNA Damage and Repair in Nondividing Cells. In P.C. Hanawalt, E.C. Freidberg, and C.F. Fox (eds.),". DNA Repair Mechanism, Academic Press, New York. 1978; : 481-4. Link

Books

1995
Marraccino, R.; Keng, PC.. "Centrifugal Elutriation". Cell Cycle: Materials and Methods. Pagano, M.. Germany: Springer-Verlag Press, 1995. 54-63
1992
Penney, DP.; Phipps, R.; Keng, PC., and Maltby, K.. "Morphologic and Functional Characteristics of Subpopulations of Murine Lung Fibroblasts Grown In Vitro.". Pulmonary Fibroblast Heterogeneity. Phipps, RP.. : CRC Press, 1992. 199-227
1991
Siemann, DW.; Keng, PC.. "Synergistic Interactions at the Solid Tumor Level through Targeting of Therapies against Two or More Different Tumor Cell Subpopulations.". Synergism and Antagonism in Chemotherapy. Chou, TC.; Rideout, DC.. New York: Academic Press, 1991. 689-713
1991
Keng, PC.. "High Capacity Separation of Homogeneous Cell Subpopulations by Centrifugal Elutriation". Cell Separation Science and Technology. Kompala, DS.; Todd, P.. New York: Academic Press, 1991. 103-113
1987
Keng, PC.; Siemann, DW.; Lord, EM.. "Separation of Malignant Cells from Host Cells Using Centrifugal Elutriation". Cell Separation Methods and Selected Applications. Pretlow, TG.; Pretlow, TP.. New York: Academic Press, 1987. 51-74
1980
Lett, JT.; Cox, AB.; Keng, PC.; Lee, AC., Su, CM.; Bergtold, DS.. "Late Degeneration in Rabbit Tissues after Irradiation by Heavy Ions.". Life Sciences and Space Research. Oxford: Pergamon Press, 1980.
1978
Lett, JT.; Keng, PC.; Sun, C.. "DNA Damage and Repair in Nondividing Cells". DNA Repair Mechanism. Hanawalt, PC; Freidberg, EC.; Fox, CF.. New York: Academic Press, 1978. 481-484