Ingrid H. Sarelius, Ph.D.

Ingrid H. Sarelius, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 711
Rochester, NY 14642

Office: (585) 275-7729
Fax: (585) 273-2652


Sarelius, I.H.. "Vascular control mechanisms in skeletal muscle.". Microvascular Research: Biology and Pathology. D. Shepro. : Academic Press, 2005. 281-285.

Journal Articles

Showing all 77 journal articles available.

2012 Nov
Corr M, Lerman I, Keubel JM, Ronacher L, Misra R, Lund F, Sarelius IH, Glading AJ. "Decreased Krev interaction-trapped 1 expression leads to increased vascular permeability and modifies inflammatory responses in vivo." Arteriosclerosis, thrombosis, and vascular biology.. 2012 Nov; 32(11):2702-10. Epub 2012 Aug 23.
2012 Jul 2
Hyun YM, Sumagin R, Sarangi PP, Lomakina E, Overstreet MG, Baker CM, Fowell DJ, Waugh RE, Sarelius IH, Kim M. "Uropod elongation is a common final step in leukocyte extravasation through inflamed vessels." The Journal of experimental medicine.. 2012 Jul 2; 209(7):1349-62. Epub 2012 Jun 18.
2011 Oct
Sumagin R, Kuebel JM, Sarelius IH. "Leukocyte rolling and adhesion both contribute to regulation of microvascular permeability to albumin via ligation of ICAM-1." American journal of physiology. Cell physiology.. 2011 Oct; 301(4):C804-13. Epub 2011 Jun 08.
2010 Aug
Sarelius I, Pohl U. "Control of muscle blood flow during exercise: local factors and integrative mechanisms." Acta physiologica (Oxford, England). 2010 Aug; 199(4):349-65. Epub 2010 Mar 26.
2010 May 1
Sumagin R, Sarelius IH. "Intercellular adhesion molecule-1 enrichment near tricellular endothelial junctions is preferentially associated with leukocyte transmigration and signals for reorganization of these junctions to accommodate leukocyte passage." The Journal of immunology : official journal of the American Association of Immunologists.. 2010 May 1; 184(9):5242-52. Epub 2010 Apr 02.
Sumagin R, Prizant H, Lomakina E, Waugh RE, Sarelius IH. "LFA-1 and Mac-1 define characteristically different intralumenal crawling and emigration patterns for monocytes and neutrophils in situ." The Journal of immunology : official journal of the American Association of Immunologists.. 2010 185(11):7057-66. Epub 2010 Oct 29.
2009 Aug
Sumagin R, Lamkin-Kennard KA, Sarelius IH. "A separate role for ICAM-1 and fluid shear in regulating leukocyte interactions with straight regions of venular wall and venular convergences." Microcirculation (New York, N.Y. : 1994). 2009 Aug; 16(6):508-20. Epub 2009 May 26.
2009 May
Lee J, Jirapatnakul AC, Reeves AP, Crowe WE, Sarelius IH. "Vessel diameter measurement from intravital microscopy." Annals of biomedical engineering.. 2009 May; 37(5):913-26. Epub 2009 Mar 11.
2008 Sep
Sumagin R, Lomakina E, Sarelius IH. "Leukocyte-endothelial cell interactions are linked to vascular permeability via ICAM-1-mediated signaling." American journal of physiology. Heart and circulatory physiology. 2008 Sep; 295(3):H969-H977. Epub 2008 Jul 18.
2008 Apr
Sumagin R, Brown CW, Sarelius IH, King MR. "Microvascular endothelial cells exhibit optimal aspect ratio for minimizing flow resistance." Annals of biomedical engineering.. 2008 Apr; 36(4):580-5. Epub 2008 Mar 04.
2008 Feb 15
Hocking DC, Titus PA, Sumagin R, Sarelius IH. "Extracellular matrix fibronectin mechanically couples skeletal muscle contraction with local vasodilation." Circulation research.. 2008 Feb 15; 102(3):372-9. Epub 2007 Nov 21.
2007 Nov
Sumagin R, Sarelius IH. "A role for ICAM-1 in maintenance of leukocyte-endothelial cell rolling interactions in inflamed arterioles." American journal of physiology. Heart and circulatory physiology. 2007 Nov; 293(5):H2786-98. Epub 2007 Aug 17.
2007 Aug
Huxley VH, Wang JJ, Sarelius IH. "Adaptation of coronary microvascular exchange in arterioles and venules to exercise training and a role for sex in determining permeability responses." American journal of physiology. Heart and circulatory physiology. 2007 Aug; 293(2):H1196-205. Epub 2007 Apr 13.
2006 Jan
Sarelius IH, Kuebel JM, Wang J, Huxley VH. "Macromolecule permeability of in situ and excised rodent skeletal muscle arterioles and venules." American journal of physiology. Heart and circulatory physiology. 2006 Jan; 290(1):H474-80. Epub 2005 Aug 26.
Sumagin, R.; Sarelius, I.H.;. "TNF-{alpha} activation of arterioles and venules alters the distribution and levels of ICAM-1 and affects leukocyte-endothelial cell interactions". Am J Physiol Heart Circ Physiol. 2006; . Link
2005 Jun
Wojciechowski JC, Sarelius IH. "Preferential binding of leukocytes to the endothelial junction region in venules in situ." Microcirculation (New York, N.Y. : 1994). 2005 Jun; 12(4):349-59.
Sarelius, I.H.; Kuebel, J.M.; Huxley, V.H.;. "Solute permeability of in situ skeletal muscle microvessels (Abstract)". Faseb Journal. 2005; 19: A179. Link
Lamkin-Kennard KA, Chuang JY, Kim MB, Sarelius IH, King MR. "The distribution of rolling neutrophils in venular convergences." Biorheology. 2005 42(5):363-83.
2004 Jun
Duza T, Sarelius IH. "Localized transient increases in endothelial cell Ca2+ in arterioles in situ: implications for coordination of vascular function." American journal of physiology. Heart and circulatory physiology. 2004 Jun; 286(6):H2322-31. Epub 2004 Feb 12.
2004 Jun
King MR, Bansal D, Kim MB, Sarelius IH. "The effect of hematocrit and leukocyte adherence on flow direction in the microcirculation." Annals of biomedical engineering.. 2004 Jun; 32(6):803-14.
2004 Mar 1
Duza T, Sarelius IH. "Increase in endothelial cell Ca(2+) in response to mouse cremaster muscle contraction." The Journal of physiology.. 2004 Mar 1; 555(Pt 2):459-69. Epub 2003 Dec 23.
2004 Mar
Murrant CL, Duza T, Kim MB, Cohen KD, Sarelius IH. "Arteriolar dilations induced by contraction of hamster cremaster muscle are dependent on changes in endothelial cell calcium." Acta physiologica Scandinavica. 2004 Mar; 180(3):231-8.
Kim MB, Sarelius IH. "Regulation of leukocyte recruitment by local wall shear rate and leukocyte delivery." Microcirculation (New York, N.Y. : 1994). 2004 11(1):55-67.
Kim MB, Sarelius IH. "Role of shear forces and adhesion molecule distribution on P-selectin-mediated leukocyte rolling in postcapillary venules." American journal of physiology. Heart and circulatory physiology. 2004 287(6):H2705-11. Epub 2004 Aug 26.
2003 Oct
King MR, Kim MB, Sarelius IH, Hammer DA. "Hydrodynamic interactions between rolling leukocytes in vivo." Microcirculation (New York, N.Y. : 1994). 2003 Oct; 10(5):401-9.
2003 Jul
Duza T, Sarelius IH. "Conducted dilations initiated by purines in arterioles are endothelium dependent and require endothelial Ca2+." American journal of physiology. Heart and circulatory physiology. 2003 Jul; 285(1):H26-37. Epub 2003 Mar 13.
2003 Apr
Kim MB, Sarelius IH. "Distributions of wall shear stress in venular convergences of mouse cremaster muscle." Microcirculation (New York, N.Y. : 1994). 2003 Apr; 10(2):167-78.
2002 Apr
Murrant CL, Sarelius IH. "Multiple dilator pathways in skeletal muscle contraction-induced arteriolar dilations." American journal of physiology. Regulatory, integrative and comparative physiology. 2002 Apr; 282(4):R969-78.
2002 Mar 1
Cohen KD, Sarelius IH. "Muscle contraction under capillaries in hamster muscle induces arteriolar dilatation via K(ATP) channels and nitric oxide." The Journal of physiology.. 2002 Mar 1; 539(Pt 2):547-55.
2000 Nov
Murrant CL, Sarelius IH. "Local and remote arteriolar dilations initiated by skeletal muscle contraction." American journal of physiology. Heart and circulatory physiology. 2000 Nov; 279(5):H2285-94.
2000 Oct
Murdock RC, Reynolds C, Sarelius IH, Waugh RE. "Adaptation and survival of surface-deprived red blood cells in mice." American journal of physiology. Cell physiology.. 2000 Oct; 279(4):C970-80.
2000 Oct
Sarelius IH, Cohen KD, Murrant CL. "Role for capillaries in coupling blood flow with metabolism." Clinical and experimental pharmacology & physiology. 2000 Oct; 27(10):826-9.
2000 Jun
Cohen KD, Berg BR, Sarelius IH. "Remote arteriolar dilations in response to muscle contraction under capillaries." American journal of physiology. Heart and circulatory physiology. 2000 Jun; 278(6):H1916-23.
2000 Apr
Murrant CL, Sarelius IH. "Coupling of muscle metabolism and muscle blood flow in capillary units during contraction." Acta physiologica Scandinavica. 2000 Apr; 168(4):531-41.
2000 Jan 24
Lau KS, Grange RW, Isotani E, Sarelius IH, Kamm KE, Huang PL, Stull JT. "nNOS and eNOS modulate cGMP formation and vascular response in contracting fast-twitch skeletal muscle." Physiological genomics. 2000 Jan 24; 2(1):21-7. Epub 2000 Jan 24.
Frame MD, Sarelius IH. "Flow-induced cytoskeletal changes in endothelial cells growing on curved surfaces." Microcirculation (New York, N.Y. : 1994). 2000 7(6 Pt 1):419-27.
1998 Jul 10
Lau KS, Grange RW, Chang WJ, Kamm KE, Sarelius I, Stull JT. "Skeletal muscle contractions stimulate cGMP formation and attenuate vascular smooth muscle myosin phosphorylation via nitric oxide." FEBS letters.. 1998 Jul 10; 431(1):71-4.
Frame MD, Chapman GB, Makino Y, Sarelius IH. "Shear stress gradient over endothelial cells in a curved microchannel system." Biorheology. 1998 35(4-5):245-61.
1997 Jun
Berg BR, Cohen KD, Sarelius IH. "Direct coupling between blood flow and metabolism at the capillary level in striated muscle." The American journal of physiology.. 1997 Jun; 272(6 Pt 2):H2693-700.
1996 Nov
Frame MD, Sarelius IH. "Endothelial cell dilatory pathways link flow and wall shear stress in an intact arteriolar network." Journal of applied physiology.. 1996 Nov; 81(5):2105-14.
1996 Jun
Frame MD, Sarelius IH. "Vascular communication and endothelial cell function in the control of arteriolar flow distribution." Microcirculation (New York, N.Y. : 1994). 1996 Jun; 3(2):233-5.
Waugh RE, Hwang WC, Sarelius IH. "Combined use of fluorescence microscopy and micromechanical measurement to assess cell and membrane properties." Pflügers Archiv : European journal of physiology.. 1996 431(6 Suppl 2):R271-2.
Waugh RE, Sarelius IH. "Effects of lost surface area on red blood cells and red blood cell survival in mice." The American journal of physiology.. 1996 271(6 Pt 1):C1847-52.
Berg BR, Sarelius IH. "Erythrocyte flux in capillary networks during maturation: implications for oxygen delivery." The American journal of physiology.. 1996 271(6 Pt 2):H2263-73.
1995 Nov
Frame MD, Sarelius IH. "Energy optimization and bifurcation angles in the microcirculation." Microvascular research. 1995 Nov; 50(3):301-10.
1995 Oct
Frame MD, Sarelius IH. "L-arginine-induced conducted signals alter upstream arteriolar responsivity to L-arginine." Circulation research.. 1995 Oct; 77(4):695-701.
1995 Mar
Sarelius IH. "Invited editorial on "Effect of RBC shape and deformability on pulmonary O2 diffusing capacity and resistance to flow in rabbit lungs"." Journal of applied physiology.. 1995 Mar; 78(3):763-4.
1995 Mar
Berg BR, Sarelius IH. "Functional capillary organization in striated muscle." The American journal of physiology.. 1995 Mar; 268(3 Pt 2):H1215-22.
Frame MD, Sarelius IH. "A system for culture of endothelial cells in 20-50-microns branching tubes." Microcirculation (New York, N.Y. : 1994). 1995 2(4):377-85.
1994 May
Kiani MF, Pries AR, Hsu LL, Sarelius IH, Cokelet GR. "Fluctuations in microvascular blood flow parameters caused by hemodynamic mechanisms." The American journal of physiology.. 1994 May; 266(5 Pt 2):H1822-8.
1993 Nov
Sarelius IH. "Cell and oxygen flow in arterioles controlling capillary perfusion." The American journal of physiology.. 1993 Nov; 265(5 Pt 2):H1682-7.
1993 Sep
Frame MD, Sarelius IH. "Arteriolar bifurcation angles vary with position and when flow is changed." Microvascular research. 1993 Sep; 46(2):190-205.
1993 Jul
Frame MD, Sarelius IH. "Regulation of capillary perfusion by small arterioles is spatially organized." Circulation research.. 1993 Jul; 73(1):155-63.
1993 May
Kiani MF, Cokelet GR, Sarelius IH. "Effect of diameter variability along a microvessel segment on pressure drop." Microvascular research. 1993 May; 45(3):219-32.
1992 Apr
Cokelet GR, Sarelius IH. "Perceived vessel lumen and cell-blood velocity ratio: impact on in vivo blood flow rate determination." The American journal of physiology.. 1992 Apr; 262(4 Pt 2):H1156-63.
1990 Jul
Sweeney TE, Sarelius IH. "Spatial heterogeneity in striated muscle arteriolar tone, cell flow, and capillarity." The American journal of physiology.. 1990 Jul; 259(1 Pt 2):H124-36.
1990 Jul
Sarelius IH. "An analysis of microcirculatory flow heterogeneity using measurements of transit time." Microvascular research. 1990 Jul; 40(1):88-98.
1990 May
Sarelius IH, Huxley VH. "A direct effect of atrial peptide on arterioles of the terminal microvasculature." The American journal of physiology.. 1990 May; 258(5 Pt 2):R1224-9.
1989 Oct
Sarelius IH. "Microcirculation in striated muscle after acute reduction in systemic hematocrit." Respiration physiology. 1989 Oct; 78(1):7-17.
1989 Jan
Sweeney TE, Sarelius IH. "Arteriolar control of capillary cell flow in striated muscle." Circulation research.. 1989 Jan; 64(1):112-20.
Sarelius IH, Nealey TA, Sweeney TE. "Variability in microvascular estimates of capillary surface area for exchange." Advances in experimental medicine and biology. 1988 242:17-21.
1986 Jun
Sarelius IH. "Cell flow path influences transit time through striated muscle capillaries." The American journal of physiology.. 1986 Jun; 250(6 Pt 2):H899-907.
1986 Mar
Sweeney TE, Sarelius IH. "Use of flow cytometry to extend and improve in vivo determinations of microvessel hematocrit and cell flux." Microvascular research. 1986 Mar; 31(2):184-96.
1985 Apr
Sarelius IH, McKinlay SM. "Statistical constraints on microvascular measurements using fluorescent erythrocytes." The American journal of physiology.. 1985 Apr; 248(4 Pt 2):H577-86.
1984 May
Federspiel WJ, Sarelius IH. "An examination of the contribution of red cell spacing to the uniformity of oxygen flux at the capillary wall." Microvascular research. 1984 May; 27(3):273-85.
1983 Aug
Sarelius IH, Maxwell LC, Gray SD, Duling BR. "Capillarity and fiber types in the cremaster muscle of rat and hamster." The American journal of physiology.. 1983 Aug; 245(2):H368-74.
Duling BR, Sarelius IH, Jackson WF. "A comparison of microvascular estimates of capillary blood flow with direct measurements of total striated muscle flow." International journal of microcirculation, clinical and experimental / sponsored by the European Society for Microcirculation. 1982 1(4):409-24.
Hughes EW, Martin-Body RL, Sarelius IH, Sinclair JD. "Effects of urethane-chloralose anaesthesia on respiration in the rat." Clinical and experimental pharmacology & physiology. 1982 9(2):119-27.
Sarelius IH, Duling BR. "Direct measurement of microvessel hematocrit, red cell flux, velocity, and transit time." The American journal of physiology.. 1982 243(6):H1018-26.
1981 Sep
Sarelius IH, Damon DN, Duling BR. "Microvascular adaptations during maturation of striated muscle." The American journal of physiology.. 1981 Sep; 241(3):H317-24.
1981 Feb
Sarelius IH, Sinclair JD. "Effects of small changes of blood volume on oxygen delivery and tissue oxygenation." The American journal of physiology.. 1981 Feb; 240(2):H177-84.
1980 Oct
Malcolm JL, Sarelius IH, Sinclair JD. "The respiratory role of the ventral surface of the medulla studied in the anaesthetized rat." The Journal of physiology.. 1980 Oct; 307:503-15.
1979 Nov 14
Sinclair JD, Sarelius IH. "The marathon man: the physiology of the long-distance runner." The New Zealand medical journal. 1979 Nov 14; 90(647):383-7.
1979 Jul
Sarelius IH. "Plasma volume shifts during moderate exercise in splenectomized greyhounds." The Journal of physiology.. 1979 Jul; 292:391-405.
1976 Oct 13
Sarelius IH. "Blood volume and exercise in dogs." The New Zealand medical journal. 1976 Oct 13; 84(573):275-6.
1975 Jun 25
Sarelius IH, Quinn JP. "Estimation of maximal oxygen uptake in New Zealanders of three age groups." The New Zealand medical journal. 1975 Jun 25; 81(542):549-52.
1975 Mar 26
Sarelius IH, Greenway RM. "Rhythmic fluctuations in the urine composition of sheep: separation of feed-dependent from other rhythms." Pflügers Archiv : European journal of physiology.. 1975 Mar 26; 355(3):243-59.