Alan E. Senior, Ph.D.

Alan E. Senior, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 712
Rochester, NY 14642

Office: (585) 275-6645
Fax: (585) 271-2683

Journal Articles

Showing all 197 journal articles available.

2012 Aug 31
Senior AE. "Two ATPases." The Journal of biological chemistry.. 2012 Aug 31; 287(36):30049-62. Epub 2012 Jul 20.
2011 Sep 13
Senior AE. "Reaction chemistry ABC-style." Proceedings of the National Academy of Sciences of the United States of America.. 2011 Sep 13; 108(37):15015-6. Epub 2011 Aug 26.
2009 Apr 17
Li W, Brudecki LE, Senior AE, Ahmad Z. "Role of {alpha}-subunit VISIT-DG sequence residues Ser-347 and Gly-351 in the catalytic sites of Escherichia coli ATP synthase." The Journal of biological chemistry.. 2009 Apr 17; 284(16):10747-54. Epub 2009 Feb 23.
2008 Feb 29
Lee JY, Urbatsch IL, Senior AE, Wilkens S. "Nucleotide-induced structural changes in P-glycoprotein observed by electron microscopy." The Journal of biological chemistry.. 2008 Feb 29; 283(9):5769-79. Epub 2007 Dec 19.
2007 Jul 27
Senior AE. "ATP synthase: motoring to the finish line." Cell.. 2007 Jul 27; 130(2):220-1.
2007 Jan 23
Carrier I, Urbatsch IL, Senior AE, Gros P. "Mutational analysis of conserved aromatic residues in the A-loop of the ABC transporter ABCB1A (mouse Mdr3)." FEBS letters.. 2007 Jan 23; 581(2):301-8. Epub 2007 Jan 03.
2006 Jan 23
Ahmad Z, Senior AE. "Inhibition of the ATPase activity of Escherichia coli ATP synthase by magnesium fluoride." FEBS letters.. 2006 Jan 23; 580(2):517-20. Epub 2005 Dec 28.
2006 Jan 1
Tombline G, Urbatsch IL, Virk N, Muharemagic A, White LB, Senior AE. "Expression, purification, and characterization of cysteine-free mouse P-glycoprotein." Archives of biochemistry and biophysics.. 2006 Jan 1; 445(1):124-8. Epub 2005 Nov 28.
2006
Senior AE, Muharemagi? A, Wilke-Mounts S. "Assembly of the stator in Escherichia coli ATP synthase. Complexation of alpha subunit with other F1 subunits is prerequisite for delta subunit binding to the N-terminal region of alpha." Biochemistry.. 2006 45(51):15893-902. Epub 2006 Dec 05.
2005 Oct 25
Delannoy S, Urbatsch IL, Tombline G, Senior AE, Vogel PD. "Nucleotide binding to the multidrug resistance P-glycoprotein as studied by ESR spectroscopy." Biochemistry.. 2005 Oct 25; 44(42):14010-9.
2005 Sep 27
Tombline G, Muharemagi? A, White LB, Senior AE. "Involvement of the "occluded nucleotide conformation" of P-glycoprotein in the catalytic pathway." Biochemistry.. 2005 Sep 27; 44(38):12879-86.
2005 Sep 6
Wilkens S, Borchardt D, Weber J, Senior AE. "Structural characterization of the interaction of the delta and alpha subunits of the Escherichia coli F1F0-ATP synthase by NMR spectroscopy." Biochemistry.. 2005 Sep 6; 44(35):11786-94.
2005 Jul 29
Ahmad Z, Senior AE. "Modulation of charge in the phosphate binding site of Escherichia coli ATP synthase." The Journal of biological chemistry.. 2005 Jul 29; 280(30):27981-9. Epub 2005 Jun 06.
2005 Jan 17
Ahmad Z, Senior AE. "Involvement of ATP synthase residues alphaArg-376, betaArg-182, and betaLys-155 in Pi binding." FEBS letters.. 2005 Jan 17; 579(2):523-8.
2005
Ahmad Z, Senior AE. "Identification of phosphate binding residues of Escherichia coli ATP synthase." Journal of bioenergetics and biomembranes. 2005 37(6):437-40.
2005
Tombline G, Senior AE. "The occluded nucleotide conformation of p-glycoprotein." Journal of bioenergetics and biomembranes. 2005 37(6):497-500.
2004 Nov 5
Tombline G, Bartholomew LA, Tyndall GA, Gimi K, Urbatsch IL, Senior AE. "Properties of P-glycoprotein with mutations in the "catalytic carboxylate" glutamate residues." The Journal of biological chemistry.. 2004 Nov 5; 279(45):46518-26. Epub 2004 Aug 23.
2004 Oct 29
Ahmad Z, Senior AE. "Role of betaAsn-243 in the phosphate-binding subdomain of catalytic sites of Escherichia coli F(1)-ATPase." The Journal of biological chemistry.. 2004 Oct 29; 279(44):46057-64. Epub 2004 Aug 20.
2004 Jul 23
Ahmad Z, Senior AE. "Mutagenesis of residue betaArg-246 in the phosphate-binding subdomain of catalytic sites of Escherichia coli F1-ATPase." The Journal of biological chemistry.. 2004 Jul 23; 279(30):31505-13. Epub 2004 May 18.
2004 Jul 23
Tombline G, Bartholomew LA, Urbatsch IL, Senior AE. "Combined mutation of catalytic glutamate residues in the two nucleotide binding domains of P-glycoprotein generates a conformation that binds ATP and ADP tightly." The Journal of biological chemistry.. 2004 Jul 23; 279(30):31212-20. Epub 2004 May 24.
2004 Jun 11
Weber J, Muharemagic A, Wilke-Mounts S, Senior AE. "Analysis of sequence determinants of F1Fo-ATP synthase in the N-terminal region of alpha subunit for binding of delta subunit." The Journal of biological chemistry.. 2004 Jun 11; 279(24):25673-9. Epub 2004 Apr 06.
2004 Mar 19
Weber J, Wilke-Mounts S, Nadanaciva S, Senior AE. "Quantitative determination of direct binding of b subunit to F1 in Escherichia coli F1F0-ATP synthase." The Journal of biological chemistry.. 2004 Mar 19; 279(12):11253-8. Epub 2004 Jan 13.
2004 Feb 13
Tombline G, Bartholomew L, Gimi K, Tyndall GA, Senior AE. "Synergy between conserved ABC signature Ser residues in P-glycoprotein catalysis." The Journal of biological chemistry.. 2004 Feb 13; 279(7):5363-73. Epub 2003 Nov 24.
2004 Feb
Senior AE, Weber J. "Happy motoring with ATP synthase." Nature structural & molecular biology. 2004 Feb; 11(2):110-2.
2004
Weber J, Senior AE. "Fluorescent probes applied to catalytic cooperativity in ATP synthase." Methods in enzymology. 2004 380:132-52.
2003 Jun 20
Urbatsch IL, Tyndall GA, Tombline G, Senior AE. "P-glycoprotein catalytic mechanism: studies of the ADP-vanadate inhibited state." The Journal of biological chemistry.. 2003 Jun 20; 278(25):23171-9. Epub 2003 Apr 01.
2003 Jun 12
Weber J, Senior AE. "ATP synthesis driven by proton transport in F1F0-ATP synthase." FEBS letters.. 2003 Jun 12; 545(1):61-70.
2003 Apr 18
Weber J, Muharemagic A, Wilke-Mounts S, Senior AE. "F1F0-ATP synthase. Binding of delta subunit to a 22-residue peptide mimicking the N-terminal region of alpha subunit." The Journal of biological chemistry.. 2003 Apr 18; 278(16):13623-6. Epub 2003 Feb 20.
2003 Apr 11
Weber J, Wilke-Mounts S, Senior AE. "Identification of the F1-binding surface on the delta-subunit of ATP synthase." The Journal of biological chemistry.. 2003 Apr 11; 278(15):13409-16. Epub 2003 Jan 29.
2002 Oct 18
Lee JY, Urbatsch IL, Senior AE, Wilkens S. "Projection structure of P-glycoprotein by electron microscopy. Evidence for a closed conformation of the nucleotide binding domains." The Journal of biological chemistry.. 2002 Oct 18; 277(42):40125-31. Epub 2002 Aug 05.
2002 May 24
Weber J, Wilke-Mounts S, Senior AE. "Quantitative determination of binding affinity of delta-subunit in Escherichia coli F1-ATPase: effects of mutation, Mg2+, and pH on Kd." The Journal of biological chemistry.. 2002 May 24; 277(21):18390-6. Epub 2002 Feb 25.
2002 Feb 15
Senior AE, Nadanaciva S, Weber J. "The molecular mechanism of ATP synthesis by F1F0-ATP synthase." Biochimica et biophysica acta.. 2002 Feb 15; 1553(3):188-211.
2002 Jan 1
Weber J, Bijol V, Wilke-Mounts S, Senior AE. "Cysteine-reactive fluorescence probes of catalytic sites of ATP synthase." Archives of biochemistry and biophysics.. 2002 Jan 1; 397(1):1-10.
2001 Sep 21
Weber J, Senior AE. "Bi-site catalysis in F1-ATPase: does it exist?" The Journal of biological chemistry.. 2001 Sep 21; 276(38):35422-8. Epub 2001 Jul 12.
2001 Jul 20
Urbatsch IL, Gimi K, Wilke-Mounts S, Lerner-Marmarosh N, Rousseau ME, Gros P, Senior AE. "Cysteines 431 and 1074 are responsible for inhibitory disulfide cross-linking between the two nucleotide-binding sites in human P-glycoprotein." The Journal of biological chemistry.. 2001 Jul 20; 276(29):26980-7. Epub 2001 May 16.
2001 Apr 1
Urbatsch IL, Wilke-Mounts S, Gimi K, Senior AE. "Purification and characterization of N-glycosylation mutant mouse and human P-glycoproteins expressed in Pichia pastoris cells." Archives of biochemistry and biophysics.. 2001 Apr 1; 388(1):171-7.
2000 Oct 13
Weber J, Nadanaciva S, Senior AE. "ATP-driven rotation of the gamma subunit in F(1)-ATPase." FEBS letters.. 2000 Oct 13; 483(1):1-5.
2000 Oct 3
Urbatsch IL, Gimi K, Wilke-Mounts S, Senior AE. "Investigation of the role of glutamine-471 and glutamine-1114 in the two catalytic sites of P-glycoprotein." Biochemistry.. 2000 Oct 3; 39(39):11921-7.
2000 Oct
Senior AE, Weber J, Nadanaciva S. "The catalytic transition state in ATP synthase." Journal of bioenergetics and biomembranes. 2000 Oct; 32(5):523-9.
2000 Aug 11
Urbatsch IL, Gimi K, Wilke-Mounts S, Senior AE. "Conserved walker A Ser residues in the catalytic sites of P-glycoprotein are critical for catalysis and involved primarily at the transition state step." The Journal of biological chemistry.. 2000 Aug 11; 275(32):25031-8.
2000 Aug 8
Nadanaciva S, Weber J, Senior AE. "New probes of the F1-ATPase catalytic transition state reveal that two of the three catalytic sites can assume a transition state conformation simultaneously." Biochemistry.. 2000 Aug 8; 39(31):9583-90.
2000 Jul
Kwan T, Loughrey H, Brault M, Gruenheid S, Urbatsch IL, Senior AE, Gros P. "Functional analysis of a tryptophan-less P-glycoprotein: a tool for tryptophan insertion and fluorescence spectroscopy." Molecular pharmacology.. 2000 Jul; 58(1):37-47.
2000 May 31
Weber J, Senior AE. "ATP synthase: what we know about ATP hydrolysis and what we do not know about ATP synthesis." Biochimica et biophysica acta.. 2000 May 31; 1458(2-3):300-9.
2000 May 9
Weber J, Senior AE. "Features of F(1)-ATPase catalytic and noncatalytic sites revealed by fluorescence lifetimes and acrylamide quenching of specifically inserted tryptophan residues." Biochemistry.. 2000 May 9; 39(18):5287-94.
2000 Jan
Senior AE, Nadanaciva S, Weber J. "Rate acceleration of ATP hydrolysis by F(1)F(o)-ATP synthase." The Journal of experimental biology. 2000 Jan; 203(Pt 1):35-40.
2000
Senior, A.E.; Nadanaciva, S.; Weber, J.;. "The catalytic transition state in ATP synthase". J. Bioenerg. Biomembr.. 2000; 32(3): 523-529.
1999 Nov 23
Nadanaciva S, Weber J, Wilke-Mounts S, Senior AE. "Importance of F1-ATPase residue alpha-Arg-376 for catalytic transition state stabilization." Biochemistry.. 1999 Nov 23; 38(47):15493-9.
1999 Jul 2
Weber J, Dunn SD, Senior AE. "Effect of the epsilon-subunit on nucleotide binding to Escherichia coli F1-ATPase catalytic sites." The Journal of biological chemistry.. 1999 Jul 2; 274(27):19124-8.
1999 Jun 15
Nadanaciva S, Weber J, Senior AE. "The role of beta-Arg-182, an essential catalytic site residue in Escherichia coli F1-ATPase." Biochemistry.. 1999 Jun 15; 38(24):7670-7.
1999 Mar 12
Nadanaciva S, Weber J, Senior AE. "Binding of the transition state analog MgADP-fluoroaluminate to F1-ATPase." The Journal of biological chemistry.. 1999 Mar 12; 274(11):7052-8.
1999
Lerner-Marmarosh N, Gimi K, Urbatsch IL, Gros P, Senior AE. "Large scale purification of detergent-soluble P-glycoprotein from Pichia pastoris cells and characterization of nucleotide binding properties of wild-type, Walker A, and Walker B mutant proteins." The Journal of biological chemistry.. 1999 274(49):34711-8.
1998 Sep 1
Senior AE, Gros P, Urbatsch IL. "Residues in P-glycoprotein catalytic sites that react with the inhibitor 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole." Archives of biochemistry and biophysics.. 1998 Sep 1; 357(1):121-5.
1998 Sep 1
Weber J, Wilke-Mounts S, Hammond ST, Senior AE. "Tryptophan substitutions surrounding the nucleotide in catalytic sites of F1-ATPase." Biochemistry.. 1998 Sep 1; 37(35):12042-50.
1998 Aug
Senior AE. "Catalytic mechanism of P-glycoprotein." Acta physiologica Scandinavica. Supplementum. 1998 Aug; 643:213-8.
1998 Jul 28
Löbau S, Weber J, Senior AE. "Catalytic site nucleotide binding and hydrolysis in F1F0-ATP synthase." Biochemistry.. 1998 Jul 28; 37(30):10846-53.
1998 Feb 2
Rebbeor JF, Senior AE. "Effects of cardiovascular drugs on ATPase activity of P-glycoprotein in plasma membranes and in purified reconstituted form." Biochimica et biophysica acta.. 1998 Feb 2; 1369(1):85-93.
1998 Jan 20
Senior AE, Bhagat S. "P-glycoprotein shows strong catalytic cooperativity between the two nucleotide sites." Biochemistry.. 1998 Jan 20; 37(3):831-6.
1998 Jan 13
Weber J, Hammond ST, Wilke-Mounts S, Senior AE. "Mg2+ coordination in catalytic sites of F1-ATPase." Biochemistry.. 1998 Jan 13; 37(2):608-14.
1998
Weber J, Senior AE. "Effects of the inhibitors azide, dicyclohexylcarbodiimide, and aurovertin on nucleotide binding to the three F1-ATPase catalytic sites measured using specific tryptophan probes." The Journal of biological chemistry.. 1998 273(50):33210-5.
1998
Senior AE, al-Shawi MK, Urbatsch IL. "ATPase activity of Chinese hamster P-glycoprotein." Methods in enzymology. 1998 292:514-23.
1997 Nov 3
Sankaran B, Bhagat S, Senior AE. "Photoaffinity labelling of P-glycoprotein catalytic sites." FEBS letters.. 1997 Nov 3; 417(1):119-22.
1997 Jul 21
Weber J, Senior AE. "Binding of TNP-ATP and TNP-ADP to the non-catalytic sites of Escherichia coli F1-ATPase." FEBS letters.. 1997 Jul 21; 412(1):169-72.
1997 Jun 3
Sankaran B, Bhagat S, Senior AE. "Inhibition of P-glycoprotein ATPase activity by beryllium fluoride." Biochemistry.. 1997 Jun 3; 36(22):6847-53.
1997 Jun
Senior AE, Gadsby DC. "ATP hydrolysis cycles and mechanism in P-glycoprotein and CFTR." Seminars in cancer biology. 1997 Jun; 8(3):143-50.
1997 May 1
Sankaran B, Bhagat S, Senior AE. "Inhibition of P-glycoprotein ATPase activity by procedures involving trapping of nucleotide in catalytic sites." Archives of biochemistry and biophysics.. 1997 May 1; 341(1):160-9.
1997 Mar 28
Weber J, Senior AE. "Catalytic mechanism of F1-ATPase." Biochimica et biophysica acta.. 1997 Mar 28; 1319(1):19-58.
1997 Mar 3
Löbau S, Weber J, Senior AE. "Nucleotide occupancy of F1-ATPase catalytic sites under crystallization conditions." FEBS letters.. 1997 Mar 3; 404(1):15-8.
1997 Feb 7
Löbau S, Weber J, Wilke-Mounts S, Senior AE. "F1-ATPase, roles of three catalytic site residues." The Journal of biological chemistry.. 1997 Feb 7; 272(6):3648-56.
1996 Aug 2
Weber J, Bowman C, Senior AE. "Specific tryptophan substitution in catalytic sites of Escherichia coli F1-ATPase allows differentiation between bound substrate ATP and product ADP in steady-state catalysis." The Journal of biological chemistry.. 1996 Aug 2; 271(31):18711-8.
1996 Jul 18
Weber J, Senior AE. "F1F0-ATP synthase: development of direct optical probes of the catalytic mechanism." Biochimica et biophysica acta.. 1996 Jul 18; 1275(1-2):101-4.
1996 Feb 16
Weber J, Senior AE. "Binding and hydrolysis of TNP-ATP by Escherichia coli F1-ATPase." The Journal of biological chemistry.. 1996 Feb 16; 271(7):3474-7.
1995 Nov 10
Urbatsch IL, Sankaran B, Bhagat S, Senior AE. "Both P-glycoprotein nucleotide-binding sites are catalytically active." The Journal of biological chemistry.. 1995 Nov 10; 270(45):26956-61.
1995 Nov
Senior AE, Weber J, al-Shawi MK. "Catalytic mechanism of Escherichia coli F1-ATPase." Biochemical Society transactions. 1995 Nov; 23(4):747-52.
1995 Sep 8
Weber J, Bowman C, Wilke-Mounts S, Senior AE. "alpha-Aspartate 261 is a key residue in noncatalytic sites of Escherichia coli F1-ATPase." The Journal of biological chemistry.. 1995 Sep 8; 270(36):21045-9.
1995 Aug 18
Urbatsch IL, Sankaran B, Weber J, Senior AE. "P-glycoprotein is stably inhibited by vanadate-induced trapping of nucleotide at a single catalytic site." The Journal of biological chemistry.. 1995 Aug 18; 270(33):19383-90.
1995 Aug 1
Schmidt G, Senior AE. "ATP-dependent inactivation of the beta-Ser339Cys mutant F1-ATPase from Escherichia coli by N-ethylmaleimide." Biochemistry.. 1995 Aug 1; 34(30):9694-9.
1995 May 26
Weber J, Senior AE. "Location and properties of pyrophosphate-binding sites in Escherichia coli F1-ATPase." The Journal of biological chemistry.. 1995 May 26; 270(21):12653-8.
1995 Apr
Gibson SL, al-Shawi MK, Senior AE, Hile R. "Inhibition of the ATPase activity of P-glycoprotein by porphyrin photosensitization of multidrug-resistant cells in vitro." Photochemistry and photobiology.. 1995 Apr; 61(4):390-6.
1995 Feb
Senior AE, al-Shawi MK, Urbatsch IL. "ATP hydrolysis by multidrug-resistance protein from Chinese hamster ovary cells." Journal of bioenergetics and biomembranes. 1995 Feb; 27(1):31-6.
1995 Jan 10
Urbatsch IL, Senior AE. "Effects of lipids on ATPase activity of purified Chinese hamster P-glycoprotein." Archives of biochemistry and biophysics.. 1995 Jan 10; 316(1):135-40.
1995
Senior AE, al-Shawi MK, Urbatsch IL. "The catalytic cycle of P-glycoprotein." FEBS letters.. 1995 377(3):285-9.
1995
Wilke-Mounts S, Pagan J, Senior AE. "Mutagenesis and reversion analysis of residue Met-209 of the beta-subunit of Escherichia coli ATP synthase." Archives of biochemistry and biophysics.. 1995 324(1):153-8.
1994 Aug 12
Weber J, Wilke-Mounts S, Senior AE. "Cooperativity and stoichiometry of substrate binding to the catalytic sites of Escherichia coli F1-ATPase. Effects of magnesium, inhibitors, and mutation." The Journal of biological chemistry.. 1994 Aug 12; 269(32):20462-7.
1994 Jun 14
Urbatsch IL, al-Shawi MK, Senior AE. "Characterization of the ATPase activity of purified Chinese hamster P-glycoprotein." Biochemistry.. 1994 Jun 14; 33(23):7069-76.
1994 Apr 15
Weber J, Wilke-Mounts S, Grell E, Senior AE. "Tryptophan fluorescence provides a direct probe of nucleotide binding in the noncatalytic sites of Escherichia coli F1-ATPase." The Journal of biological chemistry.. 1994 Apr 15; 269(15):11261-8.
1994 Mar 25
al-Shawi MK, Urbatsch IL, Senior AE. "Covalent inhibitors of P-glycoprotein ATPase activity." The Journal of biological chemistry.. 1994 Mar 25; 269(12):8986-92.
1994 Mar
Wilke-Mounts S, Weber J, Grell E, Senior AE. "Tryptophan-free Escherichia coli F1-ATPase." Archives of biochemistry and biophysics.. 1994 Mar; 309(2):363-8.
1994 Jan 7
Hazard AL, Senior AE. "Mutagenesis of subunit delta from Escherichia coli F1F0-ATP synthase." The Journal of biological chemistry.. 1994 Jan 7; 269(1):418-26.
1994 Jan 7
Hazard AL, Senior AE. "Defective energy coupling in delta-subunit mutants of Escherichia coli F1F0-ATP synthase." The Journal of biological chemistry.. 1994 Jan 7; 269(1):427-32.
1994
Grell, E.; Lewitzki, E.; Bremer C.; Kramer-Schmitt S.; Weber, J.; Senior A.E;. "Lin-Benzo-ATP and -ADP: Versatile fluorescent probes for spectroscopic and biochemical studies". J. Fluorescence. 1994; 4(3): 247-250.
1993 Sep 25
Weber J, Wilke-Mounts S, Lee RS, Grell E, Senior AE. "Specific placement of tryptophan in the catalytic sites of Escherichia coli F1-ATPase provides a direct probe of nucleotide binding: maximal ATP hydrolysis occurs with three sites occupied." The Journal of biological chemistry.. 1993 Sep 25; 268(27):20126-33.
1993 Apr 5
Turina P, Aggeler R, Lee RS, Senior AE, Capaldi RA. "The cysteine introduced into the alpha subunit of the Escherichia coli F1-ATPase by the mutation alpha R376C is near the alpha-beta subunit interface and close to a noncatalytic nucleotide binding site." The Journal of biological chemistry.. 1993 Apr 5; 268(10):6978-84.
1993 Apr 5
Senior AE, Wilke-Mounts S, al-Shawi MK. "Lysine 155 in beta-subunit is a catalytic residue of Escherichia coli F1 ATPase." The Journal of biological chemistry.. 1993 Apr 5; 268(10):6989-94.
1993 Mar 25
Weber J, Lee RS, Wilke-Mounts S, Grell E, Senior AE. "Combined application of site-directed mutagenesis, 2-azido-ATP labeling, and lin-benzo-ATP binding to study the noncatalytic sites of Escherichia coli F1-ATPase." The Journal of biological chemistry.. 1993 Mar 25; 268(9):6241-7.
1993 Feb 25
al-Shawi MK, Senior AE. "Characterization of the adenosine triphosphatase activity of Chinese hamster P-glycoprotein." The Journal of biological chemistry.. 1993 Feb 25; 268(6):4197-206.
1992 Oct 25
Senior AE, al-Shawi MK. "Further examination of seventeen mutations in Escherichia coli F1-ATPase beta-subunit." The Journal of biological chemistry.. 1992 Oct 25; 267(30):21471-8.
1992 Oct
Senior AE. "Catalytic sites of Escherichia coli F1-ATPase." Journal of bioenergetics and biomembranes. 1992 Oct; 24(5):479-84.
1992 Sep
Lee RS, Wilke-Mounts S, Senior AE. "F1-ATPase with cysteine instead of serine at residue 373 of the alpha subunit." Archives of biochemistry and biophysics.. 1992 Sep; 297(2):334-9.
1992 Sep
Senior AE, Lee RS, al-Shawi MK, Weber J. "Catalytic properties of Escherichia coli F1-ATPase depleted of endogenous nucleotides." Archives of biochemistry and biophysics.. 1992 Sep; 297(2):340-4.
1992 Jun 9
Weber J, Lee RS, Grell E, Senior AE. "Investigation of the aurovertin binding site of Escherichia coli F1-ATPase by fluorescence spectroscopy and site-directed mutagenesis." Biochemistry.. 1992 Jun 9; 31(22):5112-6.
1992 Jan 28
al-Shawi MK, Senior AE. "Catalytic sites of Escherichia coli F1-ATPase. Characterization of unisite catalysis at varied pH." Biochemistry.. 1992 Jan 28; 31(3):878-85.
1992 Jan 28
al-Shawi MK, Senior AE. "Effects of dimethyl sulfoxide on catalysis in Escherichia coli F1-ATPase." Biochemistry.. 1992 Jan 28; 31(3):886-91.
1992 Jan 25
Weber J, Lee RS, Grell E, Wise JG, Senior AE. "On the location and function of tyrosine beta 331 in the catalytic site of Escherichia coli F1-ATPase." The Journal of biological chemistry.. 1992 Jan 25; 267(3):1712-8.
1991 Jul 16
Lee RS, Pagan J, Wilke-Mounts S, Senior AE. "Characterization of Escherichia coli ATP synthase beta-subunit mutations using a chromosomal deletion strain." Biochemistry.. 1991 Jul 16; 30(28):6842-7.
1990 Oct 29
Pagan J, Senior AE. "Tight ATP and ADP binding in the noncatalytic sites of Escherichia coli F1-ATPase is not affected by mutation of bulky residues in the 'glycine-rich loop'." FEBS letters.. 1990 Oct 29; 273(1-2):147-9.
1990 Apr 5
al-Shawi MK, Parsonage D, Senior AE. "Adenosine triphosphatase and nucleotide binding activity of isolated beta-subunit preparations from Escherichia coli F1F0-ATP synthase." The Journal of biological chemistry.. 1990 Apr 5; 265(10):5595-601.
1990 Mar 15
al-Shawi MK, Parsonage D, Senior AE. "Thermodynamic analyses of the catalytic pathway of F1-ATPase from Escherichia coli. Implications regarding the nature of energy coupling by F1-ATPases." The Journal of biological chemistry.. 1990 Mar 15; 265(8):4402-10.
1990 Mar
Pagan J, Senior AE. "Mutations in alpha-subunit of Escherichia coli F1-ATPase obtained by hydroxylamine-mutagenesis of plasmids carrying the uncA gene." Archives of biochemistry and biophysics.. 1990 Mar; 277(2):283-9.
1990
Senior AE. "The proton-translocating ATPase of Escherichia coli." Annual review of biophysics and biophysical chemistry. 1990 19:7-41.
1989 Sep 15
al-Shawi MK, Parsonage D, Senior AE. "Kinetic characterization of the unisite catalytic pathway of seven beta-subunit mutant F1-ATPases from Escherichia coli." The Journal of biological chemistry.. 1989 Sep 15; 264(26):15376-83.
1989 Aug 14
Lee RS, Pagan J, Satre M, Vignais PV, Senior AE. "Identification of a mutation in Escherichia coli F1-ATPase beta-subunit conferring resistance to aurovertin." FEBS letters.. 1989 Aug 14; 253(1-2):269-72.
1989 Aug 1
Grubmeyer C, Skiadopoulos M, Senior AE. "L-histidinol dehydrogenase, a Zn2+-metalloenzyme." Archives of biochemistry and biophysics.. 1989 Aug 1; 272(2):311-7.
1989 Apr 15
Kironde FA, Parsonage D, Senior AE. "Random mutagenesis of the gene for the beta-subunit of F1-ATPase from Escherichia coli." The Biochemical journal.. 1989 Apr 15; 259(2):421-6.
1988 Nov 5
Rao R, Pagan J, Senior AE. "Directed mutagenesis of the strongly conserved lysine 175 in the proposed nucleotide-binding domain of alpha-subunit from Escherichia coli F1-ATPase." The Journal of biological chemistry.. 1988 Nov 5; 263(31):15957-63.
1988 May 9
Parsonage D, Wilke-Mounts S, Senior AE. "E. coli F1-ATPase: site-directed mutagenesis of the beta-subunit." FEBS letters.. 1988 May 9; 232(1):111-4.
1988 Apr 25
Rao R, Al-Shawi MK, Senior AE. "Trinitrophenyl-ATP and -ADP bind to a single nucleotide site on isolated beta-subunit of Escherichia coli F1-ATPase. In vitro assembly of F1-subunits requires occupancy of the nucleotide-binding site on beta-subunit by nucleoside triphosphate." The Journal of biological chemistry.. 1988 Apr 25; 263(12):5569-73.
1988 Apr 25
Rao R, Cunningham D, Cross RL, Senior AE. "Pyridoxal 5'-diphospho-5'-adenosine binds at a single site on isolated alpha-subunit from Escherichia coli F1-ATPase and specifically reacts with lysine 201." The Journal of biological chemistry.. 1988 Apr 25; 263(12):5640-5.
1988 Apr 5
Maggio MB, Parsonage D, Senior AE. "A mutation in the alpha-subunit of F1-ATPase from Escherichia coli affects the binding of F1 to the membrane." The Journal of biological chemistry.. 1988 Apr 5; 263(10):4619-23.
1988 Apr 5
Parsonage D, Al-Shawi MK, Senior AE. "Directed mutations of the strongly conserved lysine 155 in the catalytic nucleotide-binding domain of beta-subunit of F1-ATPase from Escherichia coli." The Journal of biological chemistry.. 1988 Apr 5; 263(10):4740-4.
1988 Feb 15
Parsonage D, Wilke-Mounts S, Senior AE. "Directed mutagenesis of the dicyclohexylcarbodiimide-reactive carboxyl residues in beta-subunit of F1-ATPase of Escherichia coli." Archives of biochemistry and biophysics.. 1988 Feb 15; 261(1):222-5.
1988 Jan
Senior AE. "ATP synthesis by oxidative phosphorylation." Physiological reviews.. 1988 Jan; 68(1):177-231.
1988
Al-Shawi MK, Parsonage D, Senior AE. "Directed mutagenesis of the strongly conserved aspartate 242 in the beta-subunit of Escherichia coli proton-ATPase." The Journal of biological chemistry.. 1988 263(36):19633-9.
1988
Al-Shawi MK, Senior AE. "Complete kinetic and thermodynamic characterization of the unisite catalytic pathway of Escherichia coli F1-ATPase. Comparison with mitochondrial F1-ATPase and application to the study of mutant enzymes." The Journal of biological chemistry.. 1988 263(36):19640-8.
1987 Jul 5
Maggio MB, Pagan J, Parsonage D, Hatch L, Senior AE. "The defective proton-ATPase of uncA mutants of Escherichia coli. Identification by DNA sequencing of residues in the alpha-subunit which are essential for catalysis or normal assembly." The Journal of biological chemistry.. 1987 Jul 5; 262(19):8981-4.
1987 Jun 15
Parsonage D, Wilke-Mounts S, Senior AE. "Directed mutagenesis of the beta-subunit of F1-ATPase from Escherichia coli." The Journal of biological chemistry.. 1987 Jun 15; 262(17):8022-6.
1987 Jun
Rao R, Perlin DS, Senior AE. "The defective proton-ATPase of uncA mutants of Escherichia coli: ATP-binding and ATP-induced conformational change in mutant alpha-subunits." Archives of biochemistry and biophysics.. 1987 Jun; 255(2):309-15.
1987 May 5
Parsonage D, Duncan TM, Wilke-Mounts S, Kironde FA, Hatch L, Senior AE. "The defective proton-ATPase of uncD mutants of Escherichia coli. Identification by DNA sequencing of residues in the beta-subunit which are essential for catalysis or normal assembly." The Journal of biological chemistry.. 1987 May 5; 262(13):6301-7.
1987 Feb 15
Wood JM, Wise JG, Senior AE, Futai M, Boyer PD. "Catalytic properties of the F1-adenosine triphosphatase from Escherichia coli K-12 and its genetic variants as revealed by 18O exchanges." The Journal of biological chemistry.. 1987 Feb 15; 262(5):2180-6.
1987 Feb 11
Cox GB, Hatch L, Webb D, Fimmel AL, Lin ZH, Senior AE, Gibson F. "Amino acid substitutions in the epsilon-subunit of the F1F0-ATPase of Escherichia coli." Biochimica et biophysica acta.. 1987 Feb 11; 890(2):195-204.
1987
Rao R, Senior AE. "The properties of hybrid F1-ATPase enzymes suggest that a cyclical catalytic mechanism involving three catalytic sites occurs." The Journal of biological chemistry.. 1987 262(36):17450-4.
1986 Nov 10
Duncan TM, Parsonage D, Senior AE. "Structure of the nucleotide-binding domain in the beta-subunit of Escherichia coli F1-ATPase." FEBS letters.. 1986 Nov 10; 208(1):1-6.
1985 Nov 19
Wise JG, Senior AE. "Catalytic properties of the Escherichia coli proton adenosinetriphosphatase: evidence that nucleotide bound at noncatalytic sites is not involved in regulation of oxidative phosphorylation." Biochemistry.. 1985 Nov 19; 24(24):6949-54.
1985 Jul 30
Smith RA, Latchney LR, Senior AE. "Tight divalent metal binding to Escherichia coli F1-adenosinetriphosphatase. Complete substitution of intrinsic magnesium by manganese or cobalt and studies of metal binding sites." Biochemistry.. 1985 Jul 30; 24(16):4490-4.
1985 May 31
Perlin DS, Latchney LR, Senior AE. "Inhibition of Escherichia coli H+-ATPase by venturicidin, oligomycin and ossamycin." Biochimica et biophysica acta.. 1985 May 31; 807(3):238-44.
1985 Apr 25
Duncan TM, Senior AE. "The defective proton-ATPase of uncD mutants of Escherichia coli. Two mutations which affect the catalytic mechanism." The Journal of biological chemistry.. 1985 Apr 25; 260(8):4901-7.
1985 Feb 1
Perlin DS, Senior AE. "Functional effects and cross-reactivity of antibody to purified subunit b (uncF protein) of Escherichia coli proton-ATPase." Archives of biochemistry and biophysics.. 1985 Feb 1; 236(2):603-11.
1985
Senior, A.E.;. "The Proton-ATPase of Escherichia coli". Current Topics in Membranes and Transport. 1985; 23(3): 135-151.
1984 Oct 9
Perlin DS, Latchney LR, Wise JG, Senior AE. "Specificity of the proton adenosinetriphosphatase of Escherichia coli for adenine, guanine, and inosine nucleotides in catalysis and binding." Biochemistry.. 1984 Oct 9; 23(21):4998-5003.
1984 Oct
Senior AE. "Disposition of polar and nonpolar residues on outer surfaces of transmembrane helical segments of proteins involved in proton translocation." Archives of biochemistry and biophysics.. 1984 Oct; 234(1):138-43.
1984 Mar 27
Wise JG, Latchney LR, Ferguson AM, Senior AE. "Defective proton ATPase of uncA mutants of Escherichia coli. 5'-Adenylyl imidodiphosphate binding and ATP hydrolysis." Biochemistry.. 1984 Mar 27; 23(7):1426-32.
1984 Jan
Senior AE, Latchney LR, Ferguson AM, Wise JG. "Purification of F1-ATPase with impaired catalytic activity from partial revertants of Escherichia coli uncA mutant strains." Archives of biochemistry and biophysics.. 1984 Jan; 228(1):49-53.
1983 Nov 1
Wise JG, Duncan TM, Latchney LR, Cox DN, Senior AE. "Properties of F1-ATPase from the uncD412 mutant of Escherichia coli." The Biochemical journal.. 1983 Nov 1; 215(2):343-50.
1983 Oct 15
Cox GB, Jans DA, Gibson F, Langman L, Senior AE, Fimmel AL. "Oxidative phosphorylation by mutant Escherichia coli membranes with impaired proton permeability." The Biochemical journal.. 1983 Oct 15; 216(1):143-50.
1983 Aug 25
Perlin DS, Cox DN, Senior AE. "Integration of F1 and the membrane sector of the proton-ATPase of Escherichia coli. Role of subunit "b" (uncF protein)." The Journal of biological chemistry.. 1983 Aug 25; 258(16):9793-800.
1983 Aug 1
Fimmel AL, Jans DA, Langman L, James LB, Ash GR, Downie JA, Senior AE, Gibson F, Cox GB. "The F1F0-ATPase of Escherichia coli. Substitution of proline by leucine at position 64 in the c-subunit causes loss of oxidative phosphorylation." The Biochemical journal.. 1983 Aug 1; 213(2):451-8.
1983 Jul 15
Hamlyn JM, Senior AE. "Evidence that Mg2+- or Ca2+-activated adenosine triphosphatase in rat pancreas is a plasma-membrane ecto-enzyme." The Biochemical journal.. 1983 Jul 15; 214(1):59-68.
1983 Jul 15
Senior AE. "Secondary and tertiary structure of membrane proteins involved in proton translocation." Biochimica et biophysica acta.. 1983 Jul 15; 726(2):81-95.
1983 Jun 1
Jans DA, Fimmel AL, Langman L, James LB, Downie JA, Senior AE, Ash GR, Gibson F, Cox GB. "Mutations in the uncE gene affecting assembly of the c-subunit of the adenosine triphosphatase of Escherichia coli." The Biochemical journal.. 1983 Jun 1; 211(3):717-26.
1983 Feb 15
Senior AE, Langman L, Cox GB, Gibson F. "Oxidative phosphorylation in Escherichia coli. Characterization of mutant strains in which F1-ATPase contains abnormal beta-subunits." The Biochemical journal.. 1983 Feb 15; 210(2):395-403.
1983
Senior AE, Wise JG. "The proton-ATPase of bacteria and mitochondria." The Journal of membrane biology. 1983 73(2):105-24.
1981 Nov 12
Skerrett KJ, Wise JG, Latchney LR, Senior AE. "Trypsin cleavage of the alpha-subunit of beef heart F1-ATPase abolishes ATP synthesis and ATP-driven energy-transduction capabilities." Biochimica et biophysica acta.. 1981 Nov 12; 638(1):120-4.
1981 Oct 25
Wise JG, Latchney LR, Senior AE. "The defective proton-ATPase of uncA mutants of Escherichia coli. Studies of nucleotide binding sites, bound aurovertin fluorescence, and labeling of essential residues of the purified F1-ATPase." The Journal of biological chemistry.. 1981 Oct 25; 256(20):10383-9.
1981 Oct
Cox GB, Downie JA, Langman L, Senior AE, Ash G, Fayle DR, Gibson F. "Assembly of the adenosine triphosphatase complex in Escherichia coli: assembly of F0 is dependent on the formation of specific F1 subunits." Journal of bacteriology.. 1981 Oct; 148(1):30-42.
1981 May 25
Senior AE. "Divalent metals in beef heart mitochondrial adenosine triphosphatase. Demonstration of the metals in membrane-bound enzyme and studies of the interconversion of the "1-Mg" and "2-Mg" forms of the enzyme." The Journal of biological chemistry.. 1981 May 25; 256(10):4763-7.
1980 Nov 4
Martin SS, Senior AE. "Membrane adenosine triphosphatase activities in rat pancreas." Biochimica et biophysica acta.. 1980 Nov 4; 602(2):401-18.
1980 Aug 10
Senior AE, Richardson LV, Baker K, Wise JG. "Tight divalent cation-binding sites of soluble adenosine triphosphatase (F1) from beef heart mitochondria and Escherichia coli." The Journal of biological chemistry.. 1980 Aug 10; 255(15):7211-7.
1979 Nov 25
Senior AE. "Tightly bound magnesium in mitochondrial adenosine triphosphatase from beef heart." The Journal of biological chemistry.. 1979 Nov 25; 254(22):11319-22.
1979 Apr 15
Senior AE, Downie JA, Cox GB, Gibson F, Langman L, Fayle DR. "The uncA gene codes for the alpha-subunit of the adenosine triphosphatase of Escherichia coli. Electrophoretic analysis of uncA mutant strains." The Biochemical journal.. 1979 Apr 15; 180(1):103-9.
1979 Apr 15
Senior AE, Fayle DR, Downie JA, Gibson F, Cox GB. "Properties of membranes from mutant strains of Escherichia coli in which the beta-subunit of the adenosine triphosphatase is abnormal." The Biochemical journal.. 1979 Apr 15; 180(1):111-8.
1979 Apr
Downie JA, Senior AE, Cox GB, Gibson F. "Solubilization of adenosine triphosphatase from membranes of Escherichia coli: effect of p-aminobenzamidine." Journal of bacteriology.. 1979 Apr; 138(1):87-91.
1979 Feb
Downie JA, Senior AE, Gibson F, Cox GB. "A fifth gene (uncE) in the operon concerned with oxidative phosphorylation in Escherichia coli." Journal of bacteriology.. 1979 Feb; 137(2):711-8.
1979
Smith RD, Hilf R, Senior AE. "Prolactin binding to dissociated cells from rat mammary tumors and mammary gland." Cancer biochemistry biophysics. 1979 3(3):117-21.
1979
Senior AE. "Oligomycin-sensitivity-conferring protein." Methods in enzymology. 1979 55:391-7.
1979
Senior, A.E.;. "The Mitochondrial ATPase". In "Membrane Proteins in Energy Transduction." Ed. R.A. Capaldi, Marcel Dekker, NY. 1979; : 233-278.
1978 Sep
Smith RD, Hilf R, Senior AE. "The effect of altered thyroid state on prolactin binding to liver and 7,12-dimethylbenz(a)anthracene-induced mammary tumors in rats." Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 1978 Sep; 158(4):517-20.
1978 Aug 14
Leimgruber RM, Senior AE. "Tightly-bound ATP and ADP in reconstituted submitochondrial particles." Biochemical and biophysical research communications.. 1978 Aug 14; 83(3):837-42.
1978
Senior, A.E.;. "The Reversible Mitochondrial ATPase as a Model for the Resolution of a Membrane Complex". In "The Molecular Biology of Membranes" Ed. Fleischer, S. et al., Plenum Press, NY. 1978; : 121-135.
1977 Nov
Smith RD, Hilf R, Senior AE. "Prolactin binding to 7,12-dimethylbenz(a)anthracene-induced mammary tumors and liver in diabetic rats." Cancer research.. 1977 Nov; 37(11):4070-4.
1977 Feb
Smith RD, Hilf R, Senior AE. "Prolactin binding to R3230AC mammary carcinoma and liver in hormone-treated and diabetic rats." Cancer research.. 1977 Feb; 37(2):595-8.
1976 Nov 25
Leimgruber RM, Senior AE. "Removal of "tightly bound" nucleotides from soluble mitochondrial adenosine triphosphatase (F1)." The Journal of biological chemistry.. 1976 Nov 25; 251(22):7103-9.
1976 Nov 25
Leimgruber RM, Senior AE. "Removal of "tightly bound" nucleotides from phosphorylating submitochondrial particles." The Journal of biological chemistry.. 1976 Nov 25; 251(22):7110-3.
1976 Oct
Smith RD, Hilf R, Senior AE. "Prolactin binding to mammary gland, 7,12-dimethylbenz(a)-anthracene-induced mammary tumors, and liver in rats." Cancer research.. 1976 Oct; 36(10):3726-31.
1976 Oct
Marinetti GV, Senior AE, Love R, Broadhurst CI. "Reaction of amino-phospholipids of the inner mitochondrial membrane with fluorodinitrobenzene and trinitrobenzenesulfonate." Chemistry and physics of lipids.. 1976 Oct; 17(2-3 SPEC NO):353-62.
1976
Sherratt, H.S.A.; Holland, P.C.; Osmundsen , H.; Senior, A.E.;. "On the Mechanism of Inhibition of Fatty Acid Oxidation by Hypoglycin and by Pent-4-enoic acid". In "Hypoglycin." Ed. E.A. Kean, Academic Press, N.Y.. 1976; : 127-14.
1975 Aug
Senior AE, McGowan SE, Hilf R. "A comparative study of inner membrane enzymes and transport systems in mitochondria from R3230AC mammary tumor and normal rat mammary gland." Cancer research.. 1975 Aug; 35(8):2061-7.
1975 Feb 25
Senior AE. "Mitochondrial adenosine triphosphatase. Location of sulfhydryl groups and disulfide bonds in soluble enzyme from beef heart." Biochemistry.. 1975 Feb 25; 14(4):660-4.
1975
Senior, A.E.; Tometsko, A.M.;. "Activation and Photoinactivation of F1 by 4-fluoro, 3-nitrophenylazide". In "Electron Transfer Chains and Oxidative Phosphorylation." North Holland/American Elsevier, N.Y. Ed. E. Quagliariello et al.. 1975; : 155-160.
1973 Sep 11
Senior AE. "Relationship of cysteine and tyrosine residues to adenosine triphosphate hydrolysis by mitochondrial adenine triphosphatase." Biochemistry.. 1973 Sep 11; 12(19):3622-7.
1973 Sep
Holland PC, Senior AE, Sherratt HS. "Biochemical effects of the hypoglycaemic compound pent-4-enoic acid and related non-hypoglycaemic fatty acids. Effects of their coenzyme A esters on enzymes of fatty acid oxidation." The Biochemical journal.. 1973 Sep; 136(1):173-84.
1973
Senior AE. "The structure of mitochondrial ATPase." Biochimica et biophysica acta.. 1973 301(3):249-77.
1972 Aug
Wakabayashi T, Senior AE, Hatase O, Hayashi H, Green DE. "Conformational changes in membranous preparations of cytochrome oxidase." Journal of bioenergetics. 1972 Aug; 3(5):339-44.
1972 Jul 3
Vanderkooi G, Senior AE, Capaldi RA, Hayashi H. "Biological membrane structure. 3. The lattice structure of membranous cytochrome oxidase." Biochimica et biophysica acta.. 1972 Jul 3; 274(1):38-48.
1972 Apr
Holland PC, Senior AE, Sherratt HS. "Mechanism of inhibition of fatty acid oxidation by pent-4-enoic acid: 3-oxoacyl-coenzyme A thiolase as the possible site of inhibition." The Biochemical journal.. 1972 Apr; 127(3):79P-80P.
1972
Brooks JC, Senior AE. "Methods for purification of each subunit of the mitochondrial oligomycin-insensitive adenosine triphosphatase." Biochemistry.. 1972 11(25):4675-8.
1971 Oct 1
Senior AE, Brooks JC. "The subunit composition of the mitochondrial oligomycin-insensitive ATPase." FEBS letters.. 1971 Oct 1; 17(2):327-329.
1971 Oct 1
Lambeth DO, Lardy HA, Senior AE, Brooks JC. "Reassessment of the molecular weight of mitochondrial ATPase from beef heart." FEBS letters.. 1971 Oct 1; 17(2):330-332.
1971 Aug
Senior AE. "On the relationship between the oligomycin-sensitivity conferring protein and other mitochondrial coupling factors." Journal of bioenergetics. 1971 Aug; 2(3):141-50.
1971 Apr 2
Blondin GA, DeCastro AF, Senior AE. "The isolation and properties of a peptide ionophore from beef heart mitochondria." Biochemical and biophysical research communications.. 1971 Apr 2; 43(1):28-35.
1971
Sherratt, H.S.A.; Holland, P.C; Marley, Judith; Senior, A.E.;. "Mode of Action of Hypoglycin and Related Compounds". In "Mechanisms of Toxicity," Ed. W.N. Aldridge,MacMillan & Co., London, (REVIEW).. 1971; : 205-218.
1971
Brooks JC, Senior AE. "Studies on the mitochondrial oligomycin-insensitive ATPase. II. The relationship of the specific protein inhibitor to the ATPase." Archives of biochemistry and biophysics.. 1971 147(2):467-70.
1970 Oct 10
Senior AE, MacLennan DH. "Mitochondrial "structural protein." A reassessment." The Journal of biological chemistry.. 1970 Oct 10; 245(19):5086-95.
1970 Sep
Senior AE, Brooks JC. "Studies on the mitochondrial oligomycin-insensitivt ATPase. I. An improved method of purification and the behavior of the enzyme in solutions of various depolymerizing agents." Archives of biochemistry and biophysics.. 1970 Sep; 140(1):257-66.
1969 Feb
Senior AE, Sherratt HS. "A comparison of the effects on blood glucose and ketone-body levels, and of the toxicities, of pent-4-enoic acid and four simple fatty acids." The Journal of pharmacy and pharmacology. 1969 Feb; 21(2):85-92.
1968
Senior AE, Sherratt HS. "Biochemical effects of the hypoglycaemic compound pent-4-enoic acid and related non-hypoglycaemic fatty acids. Oxidative phosphorylation and mitochondrial oxidation of pyruvate, 3-hydroxybutyrate and tricarboxylic acid-cycle intermediates." The Biochemical journal.. 1968 110(3):499-509.
1968
Senior AE, Robson B, Sherratt HS. "Biochemical effects of the hypoglycaemic compound pent--4-enoic acid and related non-hypoglycaemic fatty acids." The Biochemical journal.. 1968 110(3):511-9.
1968
Senior AE, Sherratt HS. "Biochemical effects of the hypoglycaemic compound pent-4-enoic acid and related non-hypoglycaemic fatty acids. Carbohydrate metabolism." The Biochemical journal.. 1968 110(3):521-7.
1967 Sep
Senior AE, Sherratt HS. "The effect of pent-4-enoic acid and some simple related compounds on the oxidation of fatty acids by rat-liver mitochondria." The Biochemical journal.. 1967 Sep; 104(3):56P.

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