David R. Williams, Ph.D.

David R. Williams, Ph.D.

Contact Information

Dean for Research of Arts, Science, & Engineering
William G. Allyn Professor of Medical Optics
317 Latttimore Hall
Rochester, NY 14627

Office: (585) 275-8672
Administrative: (585) 275-6049
Office: (585) 276-6070
Fax: (585) 271-3043
Fax: (585) 275-3480

Journal Articles

Showing all 68 journal articles available.

2015 Jun 1
Guevara-Torres A, Williams DR, Schallek JB. "Imaging translucent cell bodies in the living mouse retina without contrast agents." Biomedical optics express. 2015 Jun 1; 6(6):2106-19. Epub 2015 May 18.
2015 Jun 1
Zhang J, Yang Q, Saito K, Nozato K, Williams DR, Rossi EA. "An adaptive optics imaging system designed for clinical use." Biomedical optics express. 2015 Jun 1; 6(6):2120-37. Epub 2015 May 18.
2014 Nov
Masella BD, Hunter JJ, Williams DR. "Rod photopigment kinetics after photodisruption of the retinal pigment epithelium." Investigative ophthalmology & visual science. 2014 Nov; 55(11):7535-44. Epub 2014 Oct 14.
2014 Nov
Masella BD, Hunter JJ, Williams DR. "New wrinkles in retinal densitometry." Investigative ophthalmology & visual science. 2014 Nov; 55(11):7525-34. Epub 2014 Oct 14.
2014 Sep 1
Yang Q, Zhang J, Nozato K, Saito K, Williams DR, Roorda A, Rossi EA. "Closed-loop optical stabilization and digital image registration in adaptive optics scanning light ophthalmoscopy." Biomedical optics express. 2014 Sep 1; 5(9):3174-91. Epub 2014 Aug 26.
2014 Jul
Palczewska G, Dong Z, Golczak M, Hunter JJ, Williams DR, Alexander NS, Palczewski K. "Noninvasive two-photon microscopy imaging of mouse retina and retinal pigment epithelium through the pupil of the eye." Nature medicine. 2014 Jul; 20(7):785-9. Epub 2014 Jun 22.
2014 Jul
Palczewska G, Golczak M, Williams DR, Hunter JJ, Palczewski K. "Endogenous fluorophores enable two-photon imaging of the primate eye." Investigative ophthalmology & visual science. 2014 Jul; 55(7):4438-47. Epub 2014 Jun 26.
2014 Jun
Masella BD, Williams DR, Fischer W, Rossi EA, Hunter JJ. "Long-term reduction in infrared autofluorescence caused by infrared light below the maximum permissible exposure." Investigative ophthalmology & visual science. 2014 Jun; 55(6):3929-38. Epub 2014 May 20.
2014 May 7
Yin L, Masella B, Dalkara D, Zhang J, Flannery JG, Schaffer DV, Williams DR, Merigan WH. "Imaging light responses of foveal ganglion cells in the living macaque eye." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2014 May 7; 34(19):6596-605.
2014 Feb
Strazzeri JM, Hunter JJ, Masella BD, Yin L, Fischer WS, Diloreto DA, Libby RT, Williams DR, Merigan WH. "Focal damage to macaque photoreceptors produces persistent visual loss." Experimental eye research. 2014 Feb; 119:88-96. Epub 2013 Dec 05.
2013 May
Yin L, Geng Y, Osakada F, Sharma R, Cetin AH, Callaway EM, Williams DR, Merigan WH. "Imaging light responses of retinal ganglion cells in the living mouse eye." Journal of neurophysiology. 2013 May; 109(9):2415-21. Epub 2013 Feb 13.
2013
Rossi EA, Achtman RL, Guidon A, Williams DR, Roorda A, Bavelier D, Carroll J. "Visual function and cortical organization in carriers of blue cone monochromacy." PloS one. 2013 8(2):e57956. Epub 2013 Feb 28.
2013
Sharma R, Yin L, Geng Y, Merigan WH, Palczewska G, Palczewski K, Williams DR, Hunter JJ. "In vivo two-photon imaging of the mouse retina." Biomedical optics express. 2013 4(8):1285-93. Epub 2013 Jul 09.
2013
Schallek JB, Geng Y, Nguyen H, Williams DR. "Morphology and topography of retinal pericytes in the living mouse retina using in vivo adaptive optics imaging and ex vivo characterization." Investigative ophthalmology & visual science. 2013 54(13):8237-50. Epub 2013 Dec 19.
2013
Rossi EA, Rangel-Fonseca P, Parkins K, Fischer W, Latchney LR, Folwell MA, Williams DR, Dubra A, Chung MM. "In vivo imaging of retinal pigment epithelium cells in age related macular degeneration." Biomedical optics express. 2013 4(11):2527-39. Epub 2013 Oct 18.
2012 Jan
Hunter JJ, Morgan JI, Merigan WH, Sliney DH, Sparrow JR, Williams DR. "The susceptibility of the retina to photochemical damage from visible light." Progress in retinal and eye research. 2012 Jan; 31(1):28-42. Epub 2011 Nov 10.
2011 Jul 1
Williams DR. "Imaging single cells in the living retina." Vision research. 2011 Jul 1; 51(13):1379-96. Epub 2011 May 10.
2011 Mar
Rossi EA, Chung M, Dubra A, Hunter JJ, Merigan WH, Williams DR. "Imaging retinal mosaics in the living eye." Eye (London, England). 2011 Mar; 25(3):301-8.
2011 Jan 1
Doble N, Choi SS, Codona JL, Christou J, Enoch JM, Williams DR. "In vivo imaging of the human rod photoreceptor mosaic." Optics letters. 2011 Jan 1; 36(1):31-3.
2010 Aug 1
Shroff SA, Fienup JR, Williams DR. "Lateral superresolution using a posteriori phase shift estimation for a moving object: experimental results." Journal of the Optical Society of America. A, Optics, image science, and vision. 2010 Aug 1; 27(8):1770-82.
2009 Mar
Morgan JI, Dubra A, Wolfe R, Merigan WH, Williams DR. "In vivo autofluorescence imaging of the human and macaque retinal pigment epithelial cell mosaic." Investigative ophthalmology & visual science. 2009 Mar; 50(3):1350-9. Epub 2008 Oct 24.
2009 Feb
Shroff SA, Fienup JR, Williams DR. "Phase-shift estimation in sinusoidally illuminated images for lateral superresolution." Journal of the Optical Society of America. A, Optics, image science, and vision. 2009 Feb; 26(2):413-24.
2009
Geng Y, Greenberg KP, Wolfe R, Gray DC, Hunter JJ, Dubra A, Flannery JG, Williams DR, Porter J. "In vivo imaging of microscopic structures in the rat retina." Investigative ophthalmology & visual science. 2009 50(12):5872-9. Epub 2009 Jul 02.
2009
Morgan JI, Hunter JJ, Merigan WH, Williams DR. "The reduction of retinal autofluorescence caused by light exposure." Investigative ophthalmology & visual science. 2009 50(12):6015-22. Epub 2009 Jul 23.
2009
Scoles D, Gray DC, Hunter JJ, Wolfe R, Gee BP, Geng Y, Masella BD, Libby RT, Russell S, Williams DR, Merigan WH. "In-vivo imaging of retinal nerve fiber layer vasculature: imaging histology comparison." BMC ophthalmology. 2009 9:9. Epub 2009 Aug 23.
2008 Aug
Morgan JI, Hunter JJ, Masella B, Wolfe R, Gray DC, Merigan WH, Delori FC, Williams DR. "Light-induced retinal changes observed with high-resolution autofluorescence imaging of the retinal pigment epithelium." Investigative ophthalmology & visual science. 2008 Aug; 49(8):3715-29. Epub 2008 Apr 11.
2008 Jan
Gray DC, Wolfe R, Gee BP, Scoles D, Geng Y, Masella BD, Dubra A, Luque S, Williams DR, Merigan WH. "In vivo imaging of the fine structure of rhodamine-labeled macaque retinal ganglion cells." Investigative ophthalmology & visual science. 2008 Jan; 49(1):467-73.
2007 Jul 10
Doble N, Miller DT, Yoon G, Williams DR. "Requirements for discrete actuator and segmented wavefront correctors for aberration compensation in two large populations of human eyes." Applied optics. 2007 Jul 10; 46(20):4501-14.
2007 Apr 15
Sabesan R, Jeong TM, Carvalho L, Cox IG, Williams DR, Yoon G. "Vision improvement by correcting higher-order aberrations with customized soft contact lenses in keratoconic eyes." Optics letters. 2007 Apr 15; 32(8):1000-2.
2007
Chen L, Artal P, Gutierrez D, Williams DR. "Neural compensation for the best aberration correction." Journal of vision. 2007 7(10):9.1-9. Epub 2007 Jul 23.
2006 Sep
Makous W, Carroll J, Wolfing JI, Lin J, Christie N, Williams DR. "Retinal microscotomas revealed with adaptive-optics microflashes." Investigative ophthalmology & visual science. 2006 Sep; 47(9):4160-7.
2006 Aug 7
Gray DC, Merigan W, Wolfing JI, Gee BP, Porter J, Dubra A, Twietmeyer TH, Ahamd K, Tumbar R, Reinholz F, Williams DR. "In vivo fluorescence imaging of primate retinal ganglion cells and retinal pigment epithelial cells." Optics express. 2006 Aug 7; 14(16):7144-58.
2006 Jun
Wolfing JI, Chung M, Carroll J, Roorda A, Williams DR. "High-resolution retinal imaging of cone-rod dystrophy." Ophthalmology. 2006 Jun; 113(6):1019.e1. Epub 2006 May 02.
2006 Jan
Chen L, Kruger PB, Hofer H, Singer B, Williams DR. "Accommodation with higher-order monochromatic aberrations corrected with adaptive optics." Journal of the Optical Society of America. A, Optics, image science, and vision. 2006 Jan; 23(1):1-8.
2006 Jan
Porter J, Yoon G, Lozano D, Wolfing J, Tumbar R, Macrae S, Cox IG, Williams DR. "Aberrations induced in wavefront-guided laser refractive surgery due to shifts between natural and dilated pupil center locations." Journal of cataract and refractive surgery. 2006 Jan; 32(1):21-32.
2005 Nov
Porter J, Yoon G, MacRae S, Pan G, Twietmeyer T, Cox IG, Williams DR. "Surgeon offsets and dynamic eye movements in laser refractive surgery." Journal of cataract and refractive surgery. 2005 Nov; 31(11):2058-66.
2005 Oct 19
Hofer H, Carroll J, Neitz J, Neitz M, Williams DR. "Organization of the human trichromatic cone mosaic." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2005 Oct 19; 25(42):9669-79.
2005 May
Chen L, Singer B, Guirao A, Porter J, Williams DR. "Image metrics for predicting subjective image quality." Optometry and vision science : official publication of the American Academy of Optometry. 2005 May; 82(5):358-69.
2005 Jan
Yoon G, Macrae S, Williams DR, Cox IG. "Causes of spherical aberration induced by laser refractive surgery." Journal of cataract and refractive surgery. 2005 Jan; 31(1):127-35.
2005
Hofer H, Singer B, Williams DR. "Different sensations from cones with the same photopigment." Journal of vision. 2005 5(5):444-54. Epub 2005 May 19.
2005
Putnam NM, Hofer HJ, Doble N, Chen L, Carroll J, Williams DR. "The locus of fixation and the foveal cone mosaic." Journal of vision. 2005 5(7):632-9. Epub 2005 Aug 17.
2005
Choi SS, Doble N, Lin J, Christou J, Williams DR. "Effect of wavelength on in vivo images of the human cone mosaic." Journal of the Optical Society of America. A, Optics, image science, and vision. 2005 22(12):2598-605.
2004 Jun 1
Carroll J, Neitz M, Hofer H, Neitz J, Williams DR. "Functional photoreceptor loss revealed with adaptive optics: an alternate cause of color blindness." Proceedings of the National Academy of Sciences of the United States of America. 2004 Jun 1; 101(22):8461-6. Epub 2004 May 17.
2004
Yoon G, Jeong TM, Cox IG, Williams DR. "Vision improvement by correcting higher-order aberrations with phase plates in normal eyes." Journal of refractive surgery. 2004 20(5):S523-7.
2004
Fiscella K, Williams DR. "Health disparities based on socioeconomic inequities: implications for urban health care." Academic medicine : journal of the Association of American Medical Colleges. 2004 79(12):1139-47.
2003 Oct
Pallikaris A, Williams DR, Hofer H. "The reflectance of single cones in the living human eye." Investigative ophthalmology & visual science. 2003 Oct; 44(10):4580-92.
2003 Aug
Porter J, MacRae S, Yoon G, Roberts C, Cox IG, Williams DR. "Separate effects of the microkeratome incision and laser ablation on the eye's wave aberration." American journal of ophthalmology. 2003 Aug; 136(2):327-37.
2002 Feb
Yoon GY, Williams DR. "Visual performance after correcting the monochromatic and chromatic aberrations of the eye." Journal of the Optical Society of America. A, Optics, image science, and vision. 2002 Feb; 19(2):266-75.
2002
Roorda A, Williams DR. "Optical fiber properties of individual human cones." Journal of vision. 2002 2(5):404-12.
2001 Aug
Porter J, Guirao A, Cox IG, Williams DR. "Monochromatic aberrations of the human eye in a large population." Journal of the Optical Society of America. A, Optics, image science, and vision. 2001 Aug; 18(8):1793-803.
2001 Mar
Hofer H, Artal P, Singer B, Aragón JL, Williams DR. "Dynamics of the eye's wave aberration." Journal of the Optical Society of America. A, Optics, image science, and vision. 2001 Mar; 18(3):497-506.
2000 Mar 1
McMahon MJ, Lankheet MJ, Lennie P, Williams DR. "Fine structure of parvocellular receptive fields in the primate fovea revealed by laser interferometry." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2000 Mar 1; 20(5):2043-53.
1999 Feb 11
Roorda A, Williams DR. "The arrangement of the three cone classes in the living human eye." Nature. 1999 Feb 11; 397(6719):520-2.
1997 Nov
Liang J, Williams DR. "Aberrations and retinal image quality of the normal human eye." Journal of the Optical Society of America. A, Optics, image science, and vision. 1997 Nov; 14(11):2873-83.
1997 Nov
Liang J, Williams DR, Miller DT. "Supernormal vision and high-resolution retinal imaging through adaptive optics." Journal of the Optical Society of America. A, Optics, image science, and vision. 1997 Nov; 14(11):2884-92.
1996 Apr 1
Packer OS, Williams DR, Bensinger DG. "Photopigment transmittance imaging of the primate photoreceptor mosaic." The Journal of neuroscience : the official journal of the Society for Neuroscience. 1996 Apr 1; 16(7):2251-60.
1996 Apr
Miller DT, Williams DR, Morris GM, Liang J. "Images of cone photoreceptors in the living human eye." Vision research. 1996 Apr; 36(8):1067-79.
1996 Apr
Williams DR, Artal P, Navarro R, McMahon MJ, Brainard DH. "Off-axis optical quality and retinal sampling in the human eye." Vision research. 1996 Apr; 36(8):1103-14.
1994
Williams DR, Brainard DH, McMahon MJ, Navarro R. "Double-pass and interferometric measures of the optical quality of the eye." Journal of the Optical Society of America. A, Optics, image science, and vision. 1994 11(12):3123-35.
1993 Oct
Sekiguchi N, Williams DR, Brainard DH. "Aberration-free measurements of the visibility of isoluminant gratings." Journal of the Optical Society of America. A, Optics, image science, and vision. 1993 Oct; 10(10):2105-17.
1993 Oct
Sekiguchi N, Williams DR, Brainard DH. "Efficiency in detection of isoluminant and isochromatic interference fringes." Journal of the Optical Society of America. A, Optics, image science, and vision. 1993 Oct; 10(10):2118-33.
1993 Feb
Chen B, Makous W, Williams DR. "Serial spatial filters in vision." Vision research. 1993 Feb; 33(3):413-27.
1993 Jan
Brainard DH, Williams DR. "Spatial reconstruction of signals from short-wavelength cones." Vision research. 1993 Jan; 33(1):105-16.
1992 Oct
Packer O, Williams DR. "Blurring by fixational eye movements." Vision research. 1992 Oct; 32(10):1931-9.
1992
Galvin SJ, Williams DR. "No aliasing at edges in normal viewing." Vision research. 1992 32(12):2251-9.
1991
Sekiguchi N, Williams DR, Packer O. "Nonlinear distortion of gratings at the foveal resolution limit." Vision research. 1991 31(5):815-31.
1990
Coletta NJ, Williams DR, Tiana CL. "Consequences of spatial sampling for human motion perception." Vision research. 1990 30(11):1631-48.
1988
Williams DR. "Topography of the foveal cone mosaic in the living human eye." Vision research. 1988 28(3):433-54.