James Palis, M.D.

James Palis, M.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 703
Rochester, NY 14642

Office: (585) 275-5098
Fax: (585) 276-0233
Lab: (585) 275-5073
Administrative: (585) 273-2428

Books

2010
Palis J, Segel G. "Hematology of the Newborn". William's Hematology. New York, NY: McGraw-Hill, 2010.
2009
Palis J. "Molecular Biology of Erythropoiesis". Molecular Basis of Hematopoiesis. New York, NY: Springer, 2009.
2008
McGrath KE, Palis J. "Ontogeny of erythropoiesis in the mammalian embryo". Red Cell Development. Bieker J. : Elsevier Press, 2008.
2007
Palis J. "Thalassemia". The Pediatric Clinical Advisor. Garfunkel L, Kaczorowski J, Christy C. St. Louis, MO: Mosby, Inc., 2007.
2007
Palis J. "Transfusion reactions". The Pediatric Clinical Advisor. Garfunkel L, Kaczorowski J, Christy C. St. Louis, MO: Mosby, Inc., 2007.
2006
Palis, J. "Yolk sac development in mice". Hematopoietic Stem Cell Development. Godin I, Cumano A. Georgetown, TX: Landes Bioscience, 2006. 62-67
2006
Segel GB, Palis J. "Hematology of the Newborn". William's Hematology. Beutler E. New York, NY: McGraw-Hill, 2006.
2004
Palis J, Koniski A. "Analysis of hematopoietic progenitors in the mouse embryo". Developmental Regulation of Hematopoiesis: Methods and Practical Approaches. Baron M. Totowa, NJ: The Humana Press, 2004.
2002
Palis J. "Thalassemia". The Pediatric Clinical Advisor. Garfunkel L, Kaczorowski J, Christy C. St. Louis, MO: Mosby, Inc., 2002. 717-718
2002
Palis J. "Transfusion reactions". The Pediatric Clinical Advisor. Garfunkel L, Kaczorowski J, Christy C. St. Louis, MO: Mosby, Inc., 2002. 738-739
2001
Yoder M, Palis J. "Ventral (yolk sac) hematopoiesis in the mouse". Developmental Biology of Hematopoiesis. Zon LI,. New York, NY: Oxford University Press, 2001. 180-191
2001
Segel GB, Palis J. "Hematology of the Newborn". William's Hematology. Beutler E. New York, NY: McGraw-Hill, 2001. 77-92
2001
Palis J. "Iron deficiency anemia". Primary Pediatric Care. Hoekelman RA. St. Louis, MO: Mosby Yearbook, 2001. 1581-1586
1996
Palis J. "Iron deficiency anemia". Primary Pediatric Care. Hoekelman RA. St. Louis, MO: Mosby Yearbook, 1996. 1376-1381
1992
Palis J. "Iron deficiency anemia". Primary Pediatric Care. Hoekelman RA. St. Louis, MO: Mosby Yearbook, 1992. 1308-1313

Journal Articles

Showing all 71 journal articles available.

2014 Apr 15
Niswander LM, Fegan KH, Kingsley PD, McGrath KE, Palis J. "SDF-1 dynamically mediates megakaryocyte niche occupancy and thrombopoiesis at steady-state and following radiation injury." Blood.. 2014 Apr 15; Epub 2014 Apr 15.
2014 Apr 2
Getman M, England SJ, Malik J, Peterson K, Palis J, Steiner LA. "Extensively Self-Renewing Erythroblasts Derived from Transgenic ?-Yac Mice are a Novel Model System for Studying Globin Switching and Erythroid Maturation." Experimental hematology.. 2014 Apr 2; Epub 2014 Apr 02.
2014 Apr
Niswander LM, McGrath KE, Kennedy JC, Palis J. "Improved quantitative analysis of primary bone marrow megakaryocytes utilizing imaging flow cytometry." Cytometry. Part A : the journal of the International Society for Analytical Cytology.. 2014 Apr; 85(4):302-12. Epub 2014 Jan 16.
2013 Apr
Waugh RE, Huang YS, Arif BJ, Bauserman R, Palis J. "Development of membrane mechanical function during terminal stages of primitive erythropoiesis in mice." Experimental hematology.. 2013 Apr; 41(4):398-408.e2. Epub 2012 Nov 30.
2013 Feb 7
Kingsley PD, Greenfest-Allen E, Frame JM, Bushnell TP, Malik J, McGrath KE, Stoeckert CJ, Palis J. "Ontogeny of erythroid gene expression." Blood.. 2013 Feb 7; 121(6):e5-e13. Epub 2012 Dec 12.
2013
Frame JM, McGrath KE, Palis J. "Erythro-myeloid progenitors: "definitive" hematopoiesis in the conceptus prior to the emergence of hematopoietic stem cells." Blood cells, molecules & diseases.. 2013 51(4):220-5. Epub 2013 Oct 02.
2011 Apr 28
McGrath KE, Frame JM, Fromm GJ, Koniski AD, Kingsley PD, Little J, Bulger M, Palis J. "A transient definitive erythroid lineage with unique regulation of the ?-globin locus in the mammalian embryo." Blood.. 2011 Apr 28; 117(17):4600-8. Epub 2011 Mar 04.
2011 Apr
Peslak SA, Wenger J, Bemis JC, Kingsley PD, Frame JM, Koniski AD, Chen Y, Williams JP, McGrath KE, Dertinger SD, Palis J. "Sublethal radiation injury uncovers a functional transition during erythroid maturation." Experimental hematology.. 2011 Apr; 39(4):434-45. Epub 2011 Feb 01.
2011 Mar 3
England SJ, McGrath KE, Frame JM, Palis J. "Immature erythroblasts with extensive ex vivo self-renewal capacity emerge from the early mammalian fetus." Blood.. 2011 Mar 3; 117(9):2708-17. Epub 2010 Dec 02.
2010
Phonethepswath S; Franklin D; Torous DK; Bryce SM; Bemis JC; Raja S; Avlasevich S; Weller P; Hyrien O; Palis J; Macgregor JT; Dertinger SD. "Pig-a mutation: Kinetics in rat erythrocytes following exposure to five prototypical mutagens". Toxicological Sciences. 2010; 114(1): 59-70. Link
2010
Dertinger SD; Phonethepswath S; Franklin D; Weller P; Torous DK; Bryce SM; Avlasevich S; Bemis JC; Hyrien O; Palis J; Macgregor JT. "Integration of mutation and chromosomal damage endpoints into 28-day repeat dose toxicology studies". Toxicological Sciences. 2010; 115(2): 401-411. Link
2010
de Jong JL; Davidson AJ; Wang Y; Palis J; Opara P; Pugach E; Daley GQ; Zon LI. "Interaction of retinoic acid and scl controls primitive blood development." Blood. 2010; 116(2): 201-209. Link
2010
Palis J, Malik J, McGrath KE, Kingsley PD. "Primitive erythropoiesis in the mammalian embryo." The International journal of developmental biology. 2010 54(6-7):1011-8.
2010
Krance SM, Keng PC, Palis J, Ballatori N. "Transient glutathione depletion determines terminal differentiation in HL-60 cells." Oxidative medicine and cellular longevity.. 2010 3(1):53-60.
2009
Dertinger SD, Bermis JC, Phonethepswath S, Tsai Y, Nowak I, Hyrien O, Palis J, Chen Y. "Reticulocyte and micronucleated reticulocyte responses to gamma irradiation: effect of age". Mutation Research. 2009; 675: 77-80. Link
2009
Nilsson RH, Schultz IJ, Pierce EL, Soltis KA, Naranuntarat A, Ward DM, Baughman JM, Paradkar PN, Kingsley PD, Culotta VC, Kqplan J, Palis J, Paw BH, Mootha VK. "Identifying genes essential for heme biosynthesis through large-scale gene expression screening". Cell Metabolism. 2009; 10: 119-130. Link
2008
McGrath KE, Bushnell T, Palis J. "Multispectral imaging of hematopoietic cells: Where flow meets morphology". Journal of Immunological Methods. 2008; 336: 91-97. Link
2008
Lux CT; Yoshimoto M; McGrath K; Conway SJ; Palis J; Yoder MC. "All primitive and definitive hematopoietic progenitor cells emerging before E10 in the mouse embryo are products of the yolk sac". Blood. 2008; 111(7): 3435-3438. Link
2008
McGrath KE; Kingsley PD; Koniski AD; Porter RL; Bushnell TP; Palis J. "Enucleation of primitive erythroid cells generates a transient population of "pyrenocytes" in the mammalian fetus". Blood. 2008; 111(4): 2409-2417. Link
2008
Tober J; McGrath KE; Palis J. "Primitive erythropoiesis and megakaryopoiesis in the yolk sac are independent of c-myb". Blood. 2008; 111(5): 2636-2639. Link
2008
Keel SB; Doty RT; Yang Z; Quigley JG; Chen J; Knoblaugh S; Kingsley PD; De Domenico I; Vaughn MB; Kaplan J; Palis J; Abkowitz JL. "A heme export protein is required for red blood cell differentiation and iron homeostasis". Science. 2008; 319(5864): 825-828. Link
2008
McGrath K; Palis J. "Ontogeny of erythropoiesis in the mammalian embryo". Current Topics in Developmental Biology. 2008; 82: 1-22. Link
2008
Palis J. "Ontogeny of erythropoiesis". Current Opinion in Hematology. 2008; 15(3): 155-161. Link
2008
O'Brien JJ; Spinelli SL; Tober J; Blumberg N; Francis CW; Taubman MB; Palis J; Seweryniak KE; Gertz JM; Phipps RP. "15-deoxy-delta12,14-PGJ2 enhances platelet production from megakaryocytes". Blood. 2008; 112(10): 4051-4060. Link
2007
Tober J; Koniski A; McGrath KE; Vemishetti R; Emerson R; de Mesy-Bentley KK; Waugh R; Palis J. "The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis". Blood. 2007; 109(4): 1433-1441. Link
2007
Dertinger SD; Tsai Y; Nowak I; Hyrien O; Sun H; Bemis JC; Torous DK; Keng P; Palis J; Chen Y. "Reticulocyte and micronucleated reticulocyte responses to gamma irradiation: Dose-response and time-course profiles measured by flow cytometry". Mutation Research. 2007; 634(1-2): 119-125. Link
2006
Kingsley PD; Malik J; Emerson RL; Bushnell TP; McGrath KE. ""Maturational" globin switching in primary primitive erythroid cells". Blood. 2006; 107(4): 1665-1672. Link
2006
Yi Z; Cohen-Barak O; Hagiwara N; Kingsley PD; Fuchs DA. "Sox6 directly silences epsilon globin expression in definitive erythropoiesis". PLoS Genetics. 2006; 2(2): e14. Link
2005
Palis J; Koniski A. "Analysis of hematopoietic progenitors in the mouse embryo". Methods in Molecular Medicine. 2005; 105: 289-302. Link
2005
Wingert RA; Galloway JL; Barut B; Foott H; Fraenkel P; Axe JL; Weber GJ; Dooley K; Davidson AJ; Schmid B; Schmidt B; Paw BH; Shaw GC; Kingsley P; Palis J; Schubert H; Chen O; Kaplan J; Zon LI. "Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis". Nature. 2005; 436(7053): 1035-1039. Link
2005
McGrath KE; Palis J. "Hematopoiesis in the yolk sac: More than meets the eye". Experimental Hematology. 2005; 33(9): 1021-1028. Link
2004
Kingsley PD; Malik J; Fantauzzo KA; Palis J. "Yolk sac-derived primitive erythroblasts enucleate during mammalian embryogenesis". Blood. 2004; 104(1): 19-25. Link
2004
Ransom DG; Bahary N; Niss K; Traver D; Burns C; Trede NS; Paffett-Lugassy N; Saganic WJ; Lim CA; Hersey C; Zhou Y; Barut BA; Lin S; Kingsley PD; Palis J; Orkin SH; Zon LI. "The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis". PLoS Biology. 2004; 2(8): E237. Link
2004
Huber TL; Kouskoff V; Fehling HJ; Palis J; Keller G. "Haemangioblast commitment is initiated in the primitive streak of the mouse embryo". Nature. 2004; 432(7017): 625-630. Link
2003
McGrath KE; Koniski AD; Malik J; Palis J. "Circulation is established in a stepwise pattern in the mammalian embryo". Blood. 2003; 101(5): 1669-1676. Link
2003
Ji RP; Phoon CK; Aristiz√°bal O; McGrath KE; Palis J; Turnbull DH. "Onset of cardiac function during early mouse embryogenesis coincides with entry of primitive erythroblasts into the embryo proper". Circulation Research. 2003; 92(2): 133-135. Link
2003
Davidson AJ; Ernst P; Wang Y; Dekens MP; Kingsley PD; Palis J; Korsmeyer SJ; Daley GQ; Zon LI. "cdx4 mutants fail to specify blood progenitors and can be rescued by multiple hox genes". Nature. 2003; 425(6955): 300-306. Link
2002
Lewis WB; Patel U; Roberts JK; Palis J; Teot L. "Angiocentric T-cell lymphoma of the temporal bone". Otolaryngology-Head and Neck Surgery. 2002; 126(1): 85-86. Link
2002
Lacaud G; Gore L; Kennedy M; Kouskoff V; Kingsley P; Hogan C; Carlsson L; Speck N; Palis J; Keller G. "Runx1 is essential for hematopoietic commitment at the hemangioblast stage of development in vitro". Blood. 2002; 100(2): 458-466. Link
2002
Chung YS; Zhang WJ; Arentson E; Kingsley PD; Palis J; Choi K. "Lineage analysis of the hemangioblast as defined by FLK1 and SCL expression". Development. 2002; 129(23): 5511-5520. Link
2001
Kingsley PD; McGrath KE; Maltby KM; Koniski AD; Ramchandran R; Palis J. "Subtractive hybridization reveals tissue-specific expression of ahnak during embryonic development". Development, Growth & Differentiation. 2001; 43(2): 133-143. Link
2001
Palis J; Chan RJ; Koniski A; Patel R; Starr M; Yoder MC. "Spatial and temporal emergence of high proliferative potential hematopoietic precursors during murine embryogenesis". Proceedings of the National Academy of Sciences of the United States of America. 2001; 98(8): 4528-4533. Link
2001
Borrello MA; Palis J; Phipps RP. "The relationship of CD5+ B lymphocytes to macrophages: Insights from normal biphenotypic B/macrophage cells". International Reviews of Immunology.. 2001; 20(1): 137-155. Link
2001
Keith Ho HC; McGrath KE; Brodbeck KC; Palis J; Schick BP. "Serglycin proteoglycan synthesis in the murine uterine decidua and early embryo". Biology of Reproduction. 2001; 64(6): 1667-1676. Link
2001
Korones DN; Brown MR; Palis J. ""Liver function tests" are not always tests of liver function". American Journal of Hematology.. 2001; 66(1): 46-48. Link
2001
Lacaud G; Robertson S; Palis J; Kennedy M; Keller G. "Regulation of hemangioblast development". Annals of the New York Academy of Sciences. 2001; 938: 96-107, discussion 108. Link
2001
Palis J; Yoder MC. "Yolk-sac hematopoiesis: The first blood cells of mouse and man". Experimental Hematology. 2001; 29(8): 927-936. Link
2000
Donovan A; Brownlie A; Zhou Y; Shepard J; Pratt SJ; Moynihan J; Paw BH; Drejer A; Barut B; Zapata A; Law TC; Brugnara C; Lux SE; Pinkus GS; Pinkus JL; Kingsley PD; Palis J; Fleming MD; Andrews NC; Zon LI. "Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter". Nature. 2000; 403(6771): 776-781. Link
2000
Phipps RP; Pollock SJ; Kaur K; Kaufman J; Borrello MA; Graf BA; Nazarenko D; Roberts LJ; Morrow JD; Palis J; Ryan DJ; Bennett JM. "Expression of cyclooxygenase-2 and prostaglandins by B-1 cells and B-CLL cells". Current Topics in Microbiology and Immunology. 2000; 252: 293-300. Link
1999
Hetherington CJ; Kingsley PD; Crocicchio F; Zhang P; Rabin MS; Palis J; Zhang DE. "Characterization of human endotoxin lipopolysaccharide receptor CD14 expression in transgenic mice". Journal of Immunology. 1999; 162(1): 503-509. Link
1999
Liu LQ; Ilaria R; Kingsley PD; Iwama A; van Etten RA; Palis J; Zhang DE. "A novel ubiquitin-specific protease, UBP43, cloned from leukemia fusion protein AML1-ETO-expressing mice, functions in hematopoietic cell differentiation". Molecular and Cellular Biology. 1999; 19(4): 3029-3038. Link
1999
Graf BA; Nazarenko DA; Borrello MA; Roberts LJ; Morrow JD; Palis J; Phipps RP. "Biphenotypic B/macrophage cells express COX-1 and up-regulate COX-2 expression and prostaglandin E(2) production in response to pro-inflammatory signals". European Journal of Immunology. 1999; 29(11): 3793-3803. Link
1999
Palis J; Robertson S; Kennedy M; Wall C; Keller G. "Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse". Development. 1999; 126(22): 5073-5084. Link
1999
McGrath KE; Koniski AD; Maltby KM; McGann JK; Palis J. "Embryonic expression and function of the chemokine SDF-1 and its receptor, CXCR4". Developmental Biology. 1999; 213(2): 442-456. Link
1998
Palis J; Segel GB. "Developmental biology of erythropoiesis". Blood Reviews. 1998; 12(2): 106-114. Link
1998
Kingsley PD; Whitin JC; Cohen HJ; Palis J. "Developmental expression of extracellular glutathione peroxidase suggests antioxidant roles in deciduum, visceral yolk sac, and skin". Molecular Reproduction and Development. 1998; 49(4): 343-355. Link
1997
McGann JK; Silver L; Liesveld J; Palis J. "Erythropoietin-receptor expression and function during the initiation of murine yolk sac erythropoiesis". Experimental Hematology. 1997; 25(11): 1149-1157. Link
1997
McGrath KE; Palis J. "Expression of homeobox genes, including an insulin promoting factor, in the murine yolk sac at the time of hematopoietic initiation". Molecular Reproduction and Development. 1997; 48(2): 145-153. Link
1997
Silver L; Palis J. "Initiation of murine embryonic erythropoiesis: A spatial analysis". Blood. 1997; 89(4): 1154-1164. Link
1996
Kingsley PD; Zinkin AS; Silver LS; Pendola FL; Palis J. "Developmental regulation and primary structure of murine CNBP, a zinc finger-containing protein whose general structure is present in evolutionarily diverse eukaryotes". Development, Growth, and Differentiation. 1996; 38: 697-706. Link
1995
Palis J; Kingsley PD. "Differential gene expression during early murine yolk sac development". Molecular Reproduction and Development. 1995; 42(1): 19-27. Link
1995
Palis J; McGrath KE; Kingsley PD. "Initiation of hematopoiesis and vasculogenesis in murine yolk sac explants". Blood. 1995; 86(1): 156-163. Link
1994
Kingsley PD; Palis J. "GRP2 proteins contain both CCHC zinc fingers and a cold shock domain". The Plant Cell. 1994; 6(11): 1522-1523. Link
1993
Pendola F; Palis J. "MacConkey-II lactose agar for screening recombinant plasmids". Trends in Genetics. 1993; 9(1): 4. Link
1993
Kramer K; Hicks DG; Palis J; Rosier RN; Oppenheimer J; Fallon MD; Cohen HJ. "Epithelioid osteosarcoma of bone. Immunocytochemical evidence suggesting divergent epithelial and mesenchymal differentiation in a primary osseous neoplasm." Cancer. 1993; 71(10): 2977-2982. Link
1992
Reynolds SD; Angerer LM; Palis J; Nasir A; Angerer RC. "Early mRNAs, spatially restricted along the animal-vegetal axis of sea urchin embryos, include one encoding a protein related to tolloid and BMP-1". Development. 1992; 114(3): 769-786. Link
1990
Rodewald LE; Slovis CM; Palis J. "Sickle cell syndromes: Recognition and management of six crises". Emergency Medicine Reports. 1990; 11: 43-52. Link
1988
Palis J; King B; Keng P. "Separation of spontaneously differentiating and cell cycle-specific populations of HL-60 cells". Leukemia Research. 1988; 12(4): 339-344. Link
1985
Palis J.; Rossopoulos E.; Triarhou LC. "The Hippocratic concept of hysteria: A translation of the original texts". Integrative Psychiatry. 1985; 3: 226-228. Link
1983
Dacou-Voutetakis C; Palis J; Haidas S; Zannos-Mariolea L; Georgiopoulou P; Matsaniotis N. "Abnormal glucose tolerance in children with acute leukemia. Effect of induction chemotherapy including L-asparaginase". The American Journal of Pediatric Hematology/Oncology. 1983; 5(2): 139-146. Link
1979
Constantsas N; Palis J. "A reliable procedure for multiple globin synthetic determinations in isolated human reticulocytes by microzone electrophoresis". Hellenic Biochemical Biophysical Newsletter. 1979; : 5-7. Link