James Palis, M.D.

James Palis, M.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 703
Rochester, NY 14642

Office: (585) 275-5098
Fax: (585) 276-0233
Lab: (585) 275-5073
Administrative: (585) 273-2428

Journal Articles

Showing all 73 journal articles available.

2014 Jul 3
Hyrien O, Peslak SA, Yanev NM, Palis J. "Stochastic modeling of stress erythropoiesis using a two-type age-dependent branching process with immigration." Journal of mathematical biology.. 2014 Jul 3; Epub 2014 Jul 03.
2014 May 6
Dertinger SD, Avlasevich SL, Torous DK, Bemis JC, Phonethepswath S, Labash C, Carlson K, Mereness J, Cottom J, Palis J, Macgregor JT. "Persistence of Cisplatin-Induced Mutagenicity in Hematopoietic Stem Cells: Implications for Secondary Cancer Risk Following Chemotherapy." Toxicological sciences : an official journal of the Society of Toxicology.. 2014 May 6; Epub 2014 May 06.
2014 Apr 15
Niswander LM, Fegan KH, Kingsley PD, McGrath KE, Palis J. "SDF-1 dynamically mediates megakaryocyte niche occupancy and thrombopoiesis at steady-state and following radiation injury." Blood.. 2014 Apr 15; Epub 2014 Apr 15.
2014 Apr 2
Getman M, England SJ, Malik J, Peterson K, Palis J, Steiner LA. "Extensively self-renewing erythroblasts derived from transgenic ?-yac mice is a novel model system for studying globin switching and erythroid maturation." Experimental hematology.. 2014 Apr 2; Epub 2014 Apr 02.
2014 Apr
Niswander LM, McGrath KE, Kennedy JC, Palis J. "Improved quantitative analysis of primary bone marrow megakaryocytes utilizing imaging flow cytometry." Cytometry. Part A : the journal of the International Society for Analytical Cytology.. 2014 Apr; 85(4):302-12. Epub 2014 Jan 16.
2013 Apr
Waugh RE, Huang YS, Arif BJ, Bauserman R, Palis J. "Development of membrane mechanical function during terminal stages of primitive erythropoiesis in mice." Experimental hematology.. 2013 Apr; 41(4):398-408.e2. Epub 2012 Nov 30.
2013 Feb 7
Kingsley PD, Greenfest-Allen E, Frame JM, Bushnell TP, Malik J, McGrath KE, Stoeckert CJ, Palis J. "Ontogeny of erythroid gene expression." Blood.. 2013 Feb 7; 121(6):e5-e13. Epub 2012 Dec 12.
2013
Frame JM, McGrath KE, Palis J. "Erythro-myeloid progenitors: "definitive" hematopoiesis in the conceptus prior to the emergence of hematopoietic stem cells." Blood cells, molecules & diseases.. 2013 51(4):220-5. Epub 2013 Oct 02.
2011 Apr 28
McGrath KE, Frame JM, Fromm GJ, Koniski AD, Kingsley PD, Little J, Bulger M, Palis J. "A transient definitive erythroid lineage with unique regulation of the ?-globin locus in the mammalian embryo." Blood.. 2011 Apr 28; 117(17):4600-8. Epub 2011 Mar 04.
2011 Apr
Peslak SA, Wenger J, Bemis JC, Kingsley PD, Frame JM, Koniski AD, Chen Y, Williams JP, McGrath KE, Dertinger SD, Palis J. "Sublethal radiation injury uncovers a functional transition during erythroid maturation." Experimental hematology.. 2011 Apr; 39(4):434-45. Epub 2011 Feb 01.
2011 Mar 3
England SJ, McGrath KE, Frame JM, Palis J. "Immature erythroblasts with extensive ex vivo self-renewal capacity emerge from the early mammalian fetus." Blood.. 2011 Mar 3; 117(9):2708-17. Epub 2010 Dec 02.
2010 Jul 15
de Jong JL, Davidson AJ, Wang Y, Palis J, Opara P, Pugach E, Daley GQ, Zon LI. "Interaction of retinoic acid and scl controls primitive blood development." Blood.. 2010 Jul 15; 116(2):201-9. Epub 2010 Apr 21.
2010 Jun
Dertinger SD, Phonethepswath S, Franklin D, Weller P, Torous DK, Bryce SM, Avlasevich S, Bemis JC, Hyrien O, Palis J, Macgregor JT. "Integration of mutation and chromosomal damage endpoints into 28-day repeat dose toxicology studies." Toxicological sciences : an official journal of the Society of Toxicology.. 2010 Jun; 115(2):401-11. Epub 2010 Mar 04.
2010 Mar
Phonethepswath S, Franklin D, Torous DK, Bryce SM, Bemis JC, Raja S, Avlasevich S, Weller P, Hyrien O, Palis J, Macgregor JT, Dertinger SD. "Pig-a mutation: kinetics in rat erythrocytes following exposure to five prototypical mutagens." Toxicological sciences : an official journal of the Society of Toxicology.. 2010 Mar; 114(1):59-70. Epub 2009 Dec 04.
2010
Palis J, Malik J, McGrath KE, Kingsley PD. "Primitive erythropoiesis in the mammalian embryo." The International journal of developmental biology.. 2010 54(6-7):1011-8.
2010
Krance SM, Keng PC, Palis J, Ballatori N. "Transient glutathione depletion determines terminal differentiation in HL-60 cells." Oxidative medicine and cellular longevity.. 2010 3(1):53-60.
2009 Aug
Nilsson R, Schultz IJ, Pierce EL, Soltis KA, Naranuntarat A, Ward DM, Baughman JM, Paradkar PN, Kingsley PD, Culotta VC, Kaplan J, Palis J, Paw BH, Mootha VK. "Discovery of genes essential for heme biosynthesis through large-scale gene expression analysis." Cell metabolism. 2009 Aug; 10(2):119-30.
2009 Apr 30
Dertinger SD, Bemis JC, Phonethepswath S, Tsai Y, Nowak I, Hyrien O, Palis J, Chen Y. "Reticulocyte and micronucleated reticulocyte responses to gamma irradiation: effect of age." Mutation research.. 2009 Apr 30; 675(1-2):77-80. Epub 2009 Feb 11.
2008 Nov 15
O'Brien JJ, Spinelli SL, Tober J, Blumberg N, Francis CW, Taubman MB, Palis J, Seweryniak KE, Gertz JM, Phipps RP. "15-deoxy-delta12,14-PGJ2 enhances platelet production from megakaryocytes." Blood.. 2008 Nov 15; 112(10):4051-60. Epub 2008 Aug 28.
2008 Jul 31
McGrath KE, Bushnell TP, Palis J. "Multispectral imaging of hematopoietic cells: where flow meets morphology." Journal of immunological methods.. 2008 Jul 31; 336(2):91-7. Epub 2008 May 15.
2008 May
Palis J. "Ontogeny of erythropoiesis." Current opinion in hematology.. 2008 May; 15(3):155-61.
2008 Apr 1
Lux CT, Yoshimoto M, McGrath K, Conway SJ, Palis J, Yoder MC. "All primitive and definitive hematopoietic progenitor cells emerging before E10 in the mouse embryo are products of the yolk sac." Blood.. 2008 Apr 1; 111(7):3435-8. Epub 2007 Oct 11.
2008 Mar 1
Tober J, McGrath KE, Palis J. "Primitive erythropoiesis and megakaryopoiesis in the yolk sac are independent of c-myb." Blood.. 2008 Mar 1; 111(5):2636-9. Epub 2008 Jan 03.
2008 Feb 15
McGrath KE, Kingsley PD, Koniski AD, Porter RL, Bushnell TP, Palis J. "Enucleation of primitive erythroid cells generates a transient population of "pyrenocytes" in the mammalian fetus." Blood.. 2008 Feb 15; 111(4):2409-17. Epub 2007 Nov 21.
2008 Feb 8
Keel SB, Doty RT, Yang Z, Quigley JG, Chen J, Knoblaugh S, Kingsley PD, De Domenico I, Vaughn MB, Kaplan J, Palis J, Abkowitz JL. "A heme export protein is required for red blood cell differentiation and iron homeostasis." Science.. 2008 Feb 8; 319(5864):825-8.
2008
McGrath K, Palis J. "Ontogeny of erythropoiesis in the mammalian embryo." Current topics in developmental biology. 2008 82:1-22.
2007 Feb 15
Tober J, Koniski A, McGrath KE, Vemishetti R, Emerson R, de Mesy-Bentley KK, Waugh R, Palis J. "The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis." Blood.. 2007 Feb 15; 109(4):1433-41. Epub 2006 Oct 24.
2007
Dertinger SD, Tsai Y, Nowak I, Hyrien O, Sun H, Bemis JC, Torous DK, Keng P, Palis J, Chen Y. "Reticulocyte and micronucleated reticulocyte responses to gamma irradiation: dose-response and time-course profiles measured by flow cytometry." Mutation research.. 2007 634(1-2):119-25. Epub 2007 Jul 05.
2006 Feb 15
Kingsley PD, Malik J, Emerson RL, Bushnell TP, McGrath KE, Bloedorn LA, Bulger M, Palis J. ""Maturational" globin switching in primary primitive erythroid cells." Blood.. 2006 Feb 15; 107(4):1665-72. Epub 2005 Nov 01.
2006 Feb
Yi Z, Cohen-Barak O, Hagiwara N, Kingsley PD, Fuchs DA, Erickson DT, Epner EM, Palis J, Brilliant MH. "Sox6 directly silences epsilon globin expression in definitive erythropoiesis." PLoS genetics.. 2006 Feb; 2(2):e14. Epub 2006 Feb 03.
2005 Sep
McGrath KE, Palis J. "Hematopoiesis in the yolk sac: more than meets the eye." Experimental hematology.. 2005 Sep; 33(9):1021-8.
2005 Aug 18
Wingert RA, Galloway JL, Barut B, Foott H, Fraenkel P, Axe JL, Weber GJ, Dooley K, Davidson AJ, Schmid B, Schmidt B, Paw BH, Shaw GC, Kingsley P, Palis J, Schubert H, Chen O, Kaplan J, Zon LI, . "Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis." Nature.. 2005 Aug 18; 436(7053):1035-39.
2005
Palis J, Koniski A. "Analysis of hematopoietic progenitors in the mouse embryo." Methods in molecular medicine. 2005 105:289-302.
2004 Aug
Ransom DG, Bahary N, Niss K, Traver D, Burns C, Trede NS, Paffett-Lugassy N, Saganic WJ, Lim CA, Hersey C, Zhou Y, Barut BA, Lin S, Kingsley PD, Palis J, Orkin SH, Zon LI. "The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis." PLoS biology.. 2004 Aug; 2(8):E237. Epub 2004 Aug 17.
2004 Jul 1
Kingsley PD, Malik J, Fantauzzo KA, Palis J. "Yolk sac-derived primitive erythroblasts enucleate during mammalian embryogenesis." Blood.. 2004 Jul 1; 104(1):19-25. Epub 2004 Mar 18.
2004
Huber TL, Kouskoff V, Fehling HJ, Palis J, Keller G. "Haemangioblast commitment is initiated in the primitive streak of the mouse embryo." Nature.. 2004 432(7017):625-30.
2003 Sep 18
Davidson AJ, Ernst P, Wang Y, Dekens MP, Kingsley PD, Palis J, Korsmeyer SJ, Daley GQ, Zon LI. "cdx4 mutants fail to specify blood progenitors and can be rescued by multiple hox genes." Nature.. 2003 Sep 18; 425(6955):300-6.
2003 Mar 1
McGrath KE, Koniski AD, Malik J, Palis J. "Circulation is established in a stepwise pattern in the mammalian embryo." Blood.. 2003 Mar 1; 101(5):1669-76. Epub 2002 Oct 24.
2003 Feb 7
Ji RP, Phoon CK, Aristiz√°bal O, McGrath KE, Palis J, Turnbull DH. "Onset of cardiac function during early mouse embryogenesis coincides with entry of primitive erythroblasts into the embryo proper." Circulation research.. 2003 Feb 7; 92(2):133-5.
2002 Jul 15
Lacaud G, Gore L, Kennedy M, Kouskoff V, Kingsley P, Hogan C, Carlsson L, Speck N, Palis J, Keller G. "Runx1 is essential for hematopoietic commitment at the hemangioblast stage of development in vitro." Blood.. 2002 Jul 15; 100(2):458-66.
2002 Jan
Lewis WB, Patel U, Roberts JK, Palis J, Teot L. "Angiocentric T-cell lymphoma of the temporal bone." Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.. 2002 Jan; 126(1):85-6.
2002
Chung YS, Zhang WJ, Arentson E, Kingsley PD, Palis J, Choi K. "Lineage analysis of the hemangioblast as defined by FLK1 and SCL expression." Development.. 2002 129(23):5511-20.
2001 Aug
Palis J, Yoder MC. "Yolk-sac hematopoiesis: the first blood cells of mouse and man." Experimental hematology.. 2001 Aug; 29(8):927-36.
2001 Jun
Keith Ho HC, McGrath KE, Brodbeck KC, Palis J, Schick BP. "Serglycin proteoglycan synthesis in the murine uterine decidua and early embryo." Biology of reproduction.. 2001 Jun; 64(6):1667-76.
2001 Jun
Lacaud G, Robertson S, Palis J, Kennedy M, Keller G. "Regulation of hemangioblast development." Annals of the New York Academy of Sciences.. 2001 Jun; 938:96-107; discussion 108.
2001 Apr 10
Palis J, Chan RJ, Koniski A, Patel R, Starr M, Yoder MC. "Spatial and temporal emergence of high proliferative potential hematopoietic precursors during murine embryogenesis." Proceedings of the National Academy of Sciences of the United States of America.. 2001 Apr 10; 98(8):4528-33.
2001 Apr
Kingsley PD, McGrath KE, Maltby KM, Koniski AD, Ramchandran R, Palis J. "Subtractive hybridization reveals tissue-specific expression of ahnak during embryonic development." Development, growth & differentiation. 2001 Apr; 43(2):133-43.
2001 Feb
Borrello MA, Palis J, Phipps RP. "The relationship of CD5+ B lymphocytes to macrophages: insights from normal biphenotypic B/macrophage cells." International reviews of immunology. 2001 Feb; 20(1):137-55.
2001 Jan
Korones DN, Brown MR, Palis J. ""Liver function tests" are not always tests of liver function." American journal of hematology.. 2001 Jan; 66(1):46-8.
2000 Feb 17
Donovan A, Brownlie A, Zhou Y, Shepard J, Pratt SJ, Moynihan J, Paw BH, Drejer A, Barut B, Zapata A, Law TC, Brugnara C, Lux SE, Pinkus GS, Pinkus JL, Kingsley PD, Palis J, Fleming MD, Andrews NC, Zon LI. "Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter." Nature.. 2000 Feb 17; 403(6771):776-81.
2000
Phipps RP, Pollock SJ, Kaur K, Kaufman J, Borrello MA, Graf BA, Nazarenko D, Roberts LJ, Morrow JD, Palis J, Ryan DJ, Bennett JM. "Expression of cyclooxygenase-2 and prostaglandins by B-1 cells and B-CLL cells." Current topics in microbiology and immunology.. 2000 252:293-300.
1999 Nov
Palis J, Robertson S, Kennedy M, Wall C, Keller G. "Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse." Development.. 1999 Nov; 126(22):5073-84.
1999 Nov
Graf BA, Nazarenko DA, Borrello MA, Roberts LJ, Morrow JD, Palis J, Phipps RP. "Biphenotypic B/macrophage cells express COX-1 and up-regulate COX-2 expression and prostaglandin E(2) production in response to pro-inflammatory signals." European journal of immunology.. 1999 Nov; 29(11):3793-803.
1999 Sep 15
McGrath KE, Koniski AD, Maltby KM, McGann JK, Palis J. "Embryonic expression and function of the chemokine SDF-1 and its receptor, CXCR4." Developmental biology.. 1999 Sep 15; 213(2):442-56.
1999 Apr
Liu LQ, Ilaria R, Kingsley PD, Iwama A, van Etten RA, Palis J, Zhang DE. "A novel ubiquitin-specific protease, UBP43, cloned from leukemia fusion protein AML1-ETO-expressing mice, functions in hematopoietic cell differentiation." Molecular and cellular biology.. 1999 Apr; 19(4):3029-38.
1999 Jan 1
Hetherington CJ, Kingsley PD, Crocicchio F, Zhang P, Rabin MS, Palis J, Zhang DE. "Characterization of human endotoxin lipopolysaccharide receptor CD14 expression in transgenic mice." The Journal of immunology : official journal of the American Association of Immunologists.. 1999 Jan 1; 162(1):503-9.
1998 Jun
Palis J, Segel GB. "Developmental biology of erythropoiesis." Blood reviews. 1998 Jun; 12(2):106-14.
1998 Apr
Kingsley PD, Whitin JC, Cohen HJ, Palis J. "Developmental expression of extracellular glutathione peroxidase suggests antioxidant roles in deciduum, visceral yolk sac, and skin." Molecular reproduction and development. 1998 Apr; 49(4):343-55.
1997 Oct
McGrath KE, Palis J. "Expression of homeobox genes, including an insulin promoting factor, in the murine yolk sac at the time of hematopoietic initiation." Molecular reproduction and development. 1997 Oct; 48(2):145-53.
1997 Oct
McGann JK, Silver L, Liesveld J, Palis J. "Erythropoietin-receptor expression and function during the initiation of murine yolk sac erythropoiesis." Experimental hematology.. 1997 Oct; 25(11):1149-57.
1997 Feb 15
Silver L, Palis J. "Initiation of murine embryonic erythropoiesis: a spatial analysis." Blood.. 1997 Feb 15; 89(4):1154-64.
1996
Kingsley PD; Zinkin AS; Silver LS; Pendola FL; Palis J. "Developmental regulation and primary structure of murine CNBP, a zinc finger-containing protein whose general structure is present in evolutionarily diverse eukaryotes". Development, Growth, and Differentiation. 1996; 38: 697-706.
1995 Sep
Palis J, Kingsley PD. "Differential gene expression during early murine yolk sac development." Molecular reproduction and development. 1995 Sep; 42(1):19-27.
1995 Jul 1
Palis J, McGrath KE, Kingsley PD. "Initiation of hematopoiesis and vasculogenesis in murine yolk sac explants." Blood.. 1995 Jul 1; 86(1):156-63.
1994 Nov
Kingsley PD, Palis J. "GRP2 proteins contain both CCHC zinc fingers and a cold shock domain." The Plant cell. 1994 Nov; 6(11):1522-3.
1993 May 15
Kramer K, Hicks DG, Palis J, Rosier RN, Oppenheimer J, Fallon MD, Cohen HJ. "Epithelioid osteosarcoma of bone. Immunocytochemical evidence suggesting divergent epithelial and mesenchymal differentiation in a primary osseous neoplasm." Cancer.. 1993 May 15; 71(10):2977-82.
1993 Jan
Pendola F, Palis J. "MacConkey-II lactose agar for screening recombinant plasmids." Trends in genetics : TIG. 1993 Jan; 9(1):4.
1992 Mar
Reynolds SD, Angerer LM, Palis J, Nasir A, Angerer RC. "Early mRNAs, spatially restricted along the animal-vegetal axis of sea urchin embryos, include one encoding a protein related to tolloid and BMP-1." Development.. 1992 Mar; 114(3):769-86.
1990
Rodewald LE; Slovis CM; Palis J. "Sickle cell syndromes: Recognition and management of six crises". Emergency Medicine Reports. 1990; 11: 43-52.
1988
Palis J, King B, Keng P. "Separation of spontaneously differentiating and cell cycle-specific populations of HL-60 cells." Leukemia research.. 1988 12(4):339-44.
1985
Palis J.; Rossopoulos E.; Triarhou LC. "The Hippocratic concept of hysteria: A translation of the original texts". Integrative Psychiatry. 1985; 3: 226-228.
1983
Dacou-Voutetakis C, Palis J, Haidas S, Zannos-Mariolea L, Georgiopoulou P, Matsaniotis N. "Abnormal glucose tolerance in children with acute leukemia. Effect of induction chemotherapy including L-asparaginase." The American journal of pediatric hematology/oncology. 1983 5(2):139-46.
1979
Constantsas N; Palis J. "A reliable procedure for multiple globin synthetic determinations in isolated human reticulocytes by microzone electrophoresis". Hellenic Biochemical Biophysical Newsletter. 1979; : 5-7.

Books

2010
Palis J, Segel G. "Hematology of the Newborn". William's Hematology. New York, NY: McGraw-Hill, 2010.
2009
Palis J. "Molecular Biology of Erythropoiesis". Molecular Basis of Hematopoiesis. New York, NY: Springer, 2009.
2008
McGrath KE, Palis J. "Ontogeny of erythropoiesis in the mammalian embryo". Red Cell Development. Bieker J. : Elsevier Press, 2008.
2007
Palis J. "Thalassemia". The Pediatric Clinical Advisor. Garfunkel L, Kaczorowski J, Christy C. St. Louis, MO: Mosby, Inc., 2007.
2007
Palis J. "Transfusion reactions". The Pediatric Clinical Advisor. Garfunkel L, Kaczorowski J, Christy C. St. Louis, MO: Mosby, Inc., 2007.
2006
Palis, J. "Yolk sac development in mice". Hematopoietic Stem Cell Development. Godin I, Cumano A. Georgetown, TX: Landes Bioscience, 2006. 62-67
2006
Segel GB, Palis J. "Hematology of the Newborn". William's Hematology. Beutler E. New York, NY: McGraw-Hill, 2006.
2004
Palis J, Koniski A. "Analysis of hematopoietic progenitors in the mouse embryo". Developmental Regulation of Hematopoiesis: Methods and Practical Approaches. Baron M. Totowa, NJ: The Humana Press, 2004.
2002
Palis J. "Thalassemia". The Pediatric Clinical Advisor. Garfunkel L, Kaczorowski J, Christy C. St. Louis, MO: Mosby, Inc., 2002. 717-718
2002
Palis J. "Transfusion reactions". The Pediatric Clinical Advisor. Garfunkel L, Kaczorowski J, Christy C. St. Louis, MO: Mosby, Inc., 2002. 738-739
2001
Yoder M, Palis J. "Ventral (yolk sac) hematopoiesis in the mouse". Developmental Biology of Hematopoiesis. Zon LI,. New York, NY: Oxford University Press, 2001. 180-191
2001
Segel GB, Palis J. "Hematology of the Newborn". William's Hematology. Beutler E. New York, NY: McGraw-Hill, 2001. 77-92
2001
Palis J. "Iron deficiency anemia". Primary Pediatric Care. Hoekelman RA. St. Louis, MO: Mosby Yearbook, 2001. 1581-1586
1996
Palis J. "Iron deficiency anemia". Primary Pediatric Care. Hoekelman RA. St. Louis, MO: Mosby Yearbook, 1996. 1376-1381
1992
Palis J. "Iron deficiency anemia". Primary Pediatric Care. Hoekelman RA. St. Louis, MO: Mosby Yearbook, 1992. 1308-1313