Marc W. Halterman, M.D., Ph.D.

Marc W. Halterman, M.D., Ph.D.

Contact Information

Rochester General Hospital
1425 Portland Avenue
Department of Neurology
Rochester, NY 14621

Lab: (585) 275-6663

Research Bio

Dr. Halterman's laboratory studies the damage associated with global brain ischemia, with a particular focus on identifying novel therapeutic targets in transcriptional signaling networks. Using a variety of models, they study the effects of hypoxia-ischemia on both the adult nervous system as well as the progenitor cells active within the immature and adult brain. His laboratory is supported by grants from the NIH/NINDS. He also has extensive experience in the field of gene therapy and holds several patents in the areas of gene transfer, drug discovery and medical informatics.

Awards & Honors (National)

K99/R00 Fellowship | NIH/NINDS 2008 - Present
Alpha Omega Alpha | University of Rochester 2001 - Present
NIH Individual Pre-doctoral Combined MD PhD Fellowship | National instititues of Health | University of Rochester 1998

Awards & Honors (Local)

Henry C. Buswell Fellowship Award | Department of Medicine, URMC 2007
Doctor of Medicine with Distinction in Research | University of Rochester SMD | University of Rochester 2002
Gilbert B. Forbes Prize in Pediatric Research | University of Rochester 1994

Patents

DUSP1/MKP-1 as a Therapeutic Target for Stroke

United States Serial NO.: 13/501,066
Filed Date: October 9, 2010
Title: Methods of Treatment and Screening Assays for HIF-1Alpha Regulation
Invented by: Marc Halterman
Medical Expert System to Improve Provider Performance at the Point of Care Using Expert Crowdsourcing

United States Serial NO.: 13/429,298
Filed Date: March 23, 2012
Title: Crowdsourcing Medical Expertise
Invented by: Marc Halterman, Jeffrey Bigham, Henry Kautz

Recent Journal Articles

Showing the 5 most recent journal articles. 33 available »

2014 Jan 16
Matthews TA, Abel A, Demme C, Sherman T, Pan PW, Halterman MW, Parkkila S, Nehrke K. "Expression of the CHOP-inducible carbonic anhydrase CAVI-b is required for BDNF-mediated protection from hypoxia." Brain research.. 2014 Jan 16; 1543:28-37. Epub 2013 Nov 23.
2012 Oct
Rininger A, Dejesus C, Totten A, Wayland A, Halterman MW. "MKP-1 antagonizes C/EBP? activity and lowers the apoptotic threshold after ischemic injury." Cell death and differentiation. 2012 Oct; 19(10):1634-43. Epub 2012 Apr 20.
2012 Jun 15
Rininger A, Wayland A, Prifti V, Halterman MW. "Assessment of CA1 injury after global ischemia using supervised 2D analyses of nuclear pyknosis." Journal of neuroscience methods.. 2012 Jun 15; 207(2):181-8. Epub 2012 Apr 21.
2011 Mar
Segel GB, Halterman MW, Lichtman MA. "The paradox of the neutrophil's role in tissue injury." Journal of leukocyte biology.. 2011 Mar; 89(3):359-72. Epub 2010 Nov 19.
2011 Mar
Halterman MW. "An improved method for the study of apoptosis-related genes using the tet-on system." Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening. 2011 Mar; 16(3):332-7. Epub 2011 Feb 18.

Current Appointments

Associate Professor - Department of Neurology, Neurology - RGH (SMD) - Primary
Associate Professor - Department of Pediatrics (SMD)

Specialties

Neurology - American Board of Psychiatry and Neurology

Education

PhD | Microbiology | Univ Rochester Sch Med/Dent2002
MD | Medicine | Univ Rochester Sch Med/Dent2002
MS | Microbiology | Univ Rochester Sch Med/Dent1999
BS | Chemistry | Georgetown University1992

Post-Doctoral Training & Residency

Research at Strong Memorial Hospital- GME Office01/01/2007 - 07/01/2007
Fellowship in Neurology at Strong Memorial Hospital- GME Office
Residency in Neurology at University of Rochester Medical Center07/01/2003 - 06/30/2006
Internship in Internal Medicine at University of Rochester Medical Center06/24/2002 - 06/23/2003