Constantine G. Haidaris, Ph.D.

Constantine G. Haidaris, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 672
Rochester, NY 14642

Office: (585) 275-0678
Lab: (585) 275-0657

Research Bio

Research Description:



Research in my lab focuses on infections in the immunocompromised host. We examine mechanisms of pathogenesis, host-microbe interactions and approaches to therapy. Much of our recent work centers on a novel approach to treat of infections termed photodynamic therapy, in which a chemical agent termed a photosensitizer is activated by light to convert molecular oxygen to reactive oxygen species that are toxic for the target cell. In collaboration with colleagues in the Departments of Physics and Imaging Sciences, we are exploring mechanisms to increase the sensitivity of pathogens to antimicrobial photodynamic therapy and developing methods to treat experimental infections using this technology.

Recent Journal Articles

Showing the 5 most recent journal articles. 64 available »

2015 Jul
Falsetta ML, Foster DC, Woeller CF, Pollock SJ, Bonham AD, Haidaris CG, Stodgell CJ, Phipps RP. "Identification of novel mechanisms involved in generating localized vulvodynia pain." American journal of obstetrics and gynecology. 2015 Jul; 213(1):38.e1-38.e12. Epub 2015 Feb 12.
2015 Mar
Foster DC, Falsetta ML, Woeller CF, Pollock SJ, Song K, Bonham A, Haidaris CG, Stodgell CJ, Messing SP, Iadarola M, Phipps RP. "Site-specific mesenchymal control of inflammatory pain to yeast challenge in vulvodynia-afflicted and pain-free women." Pain. 2015 Mar; 156(3):386-96.
2013 Oct
Haidaris CG, Foster TH, Waldman DL, Mathes EJ, McNamara J, Curran T. "Effective photodynamic therapy against microbial populations in human deep tissue abscess aspirates." Lasers in surgery and medicine. 2013 Oct; 45(8):509-16. Epub 2013 Aug 29.
2012
Snell SB, Foster TH, Haidaris CG. "Miconazole induces fungistasis and increases killing of Candida albicans subjected to photodynamic therapy." Photochemistry and photobiology. 2012 88(3):596-603. Epub 2011 Dec 20.
2011 Apr
Mitra S, Haidaris CG, Snell SB, Giesselman BR, Hupcher SM, Foster TH. "Effective photosensitization and selectivity in vivo of Candida Albicans by meso-tetra (N-methyl-4-pyridyl) porphine tetra tosylate." Lasers in surgery and medicine. 2011 Apr; 43(4):324-32.

Current Appointments

Associate Professor - Department of Microbiology and Immunology (SMD) - Primary
Associate Professor - Center for Oral Biology

Education

PhD | Microbiology | Univ Cincinnati Coll Medicine1982
MS | Microbiology | Miami University1976
BA | Biology | Wittenberg University1974