Barbara L. Asselin, M.D.

Barbara L. Asselin, M.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 777
Rochester, NY 14642

Office: (585) 276-4113
Fax: (585) 276-1128
Administrative: (585) 276-4113

Journal Articles

Showing all 52 journal articles available.

2014
Tower RL, Jones TL, Camitta BM, Asselin BL, Bell BA, Chauvenet A, Devidas M, Halperin EC, Pullen J, Shuster JJ, Winick N, and Kurtzberg J. "Dose intensification of methotrexate and cytarabine during intensified continuation chemotherapy for high-risk B-precursor acute lymphoblastic leukemia: POG 9406: A report from the Children's Oncology Group." Journal of Pediatric Hematology/Oncology. 2014; 36(5): 353-61.
2013
Vrooman, LM; Neuberg, DS; Supko, JG; Kutok, JL; Dahlberg, S; Stevenson, K; O'Brien, J; Asselin, BL; Athale, UH; Clavell, L; Kelly, KM; Laverdiere, C; Lipshultz, SE; Michon, B; Schorin, M; Cohen, HJ; Sallan, SE; Silverman, LB. "Efficacy of Individualized Dosing of L-Asparaginase and Dexamethasone in Children and Adolescents with Newly Diagnosed Acute Lymphoblastic Leukemia: Results from the Dana-Farber Cancer Institute Acute Lymphoblastic Leukemia Consortium Protocol 00-01." J Clin Oncology. 2013; 31(9): 1202-10.
2013
Salzer, WL; Asselin, BL; Supko JG; Devidas M; Kaiser NA; Plourde P; Winick NJ; Reaman GH; Raetz E; Carroll WL; and Hunger SP. "Erwina asparaginase achieves therapeutic activity after PEG-asparaginase allergy: A report from the Children's Oncology Group". Blood. 2013; .
2013
Sears B, Bailes J, Asselin B. "Therapeutic uses of high-dose omega-3 fatty acids to treat comatose patients with severe brain injury." Pharma Nutrition. 2013; 1: 86-89.
2013
Asselin BL, Gaynon P, Whitlock JA. "Recent advances in acute lymphoblastic leukemia in children and adolescents: an expert panel discussion." Curr Opin Oncol. 2013; 25 Suppl, 3: S1-13; quiz S14-6.
2013
Liesveld J, Asselin B. "It's all in the liposomes: Vincristine gets a new package." J Clin Oncol Epub & J Clin Oncol. 2013; 31(6): 657-9.
2013
Vrooman LM, Stevenson KE, Supko JG, O'Brien J, Dahlberg SE, Asselin BL, Athale UH, Clavell LA, Kelly KM, Kutok JL, Laverdiere C, Lipshultz SE, Michon B, Schorin M, Relling MV, Cohen HJ, Neuberg DS, Sallan SE, and Silverman LB. "Post-induction dexamethasone and individualized dosing of E. coli L-asparaginase each improve outcome of children and adolescents with newly diagnosed acute lymphoblastic leukemia: Results from a randomized study, Dana-Farber Cancer Institute ALL Consortium Protocol 00-01." J Clin Oncol Epub & J Clin Oncol. 2013; 31(9): 1202-10.
2013
Salzer WL, Asselin B, Supko JG, Devidas M, Kaiser NA, Plourde P, Winick NJ, Reaman GH, Raetz E, Carroll WL, and Hunger SP. "Erwinia asparaginase achieves therapeutic activity after PEG-asparaginase allergy: A report from the Children's Oncology Group." Blood. 2013; 122(4): 507-14.
2013
Lipshultz SE, Lipsitz SR, Kutok JL, Miller TL, Colan SD, Neuberg DS, Stevenson KE, Fleming MD, Sallan SE, Franco VI, Henkel JM, Asselin BL, Athale UH, Clavell LA, Michon B, Laverdiere C, Larsen E, Kelly KM, and Silverman LB. "Impact of hemochromatosis gene mutations on cardiac status in doxorubicin-treated survivors of childhood high-risk leukemia." Cancer. 2013; 119(19): 3555-62.
2012
Asselin BL. "Inside Blood: The right dose for the right patient." Blood. 2012; 119(7): 1617-18.
2012
Lipshultz SE, Miller TL, Lipsitz SR, Neuberg DS, Dahlberg SE, Colan SD, Silverman LB, Henkel JM, Franco VI, Cushman LL, Asselin BL, Clavell LA, Athale U, Michon B, Laverdiere C, Schorin MA, Larsen E, Usmani N, Sallan SE. "Continuous versus bolus-infusion of doxorubicin in children with high-risk acute lymphoblastic leukemia: long-term cardiac outcomes." Pediatrics Epub & Pediatrics. 2012; 130(6): 1003-11.
2012
Lipshultz SE, Miller TL, Scully RE, Lipsitz SR, Rifai N, Silverman LB, Colan SD, Neuberg DS, Dahlberg SE, Henkel JM, Asselin BL, Athale UH, Clavell LA, Laverdiere C, Michon B, Schorin MA, and Sallan SE. "Changes in cardiac biomarkers during doxorubicin treatment of pediatric patients with high-risk acute lymphoblastic leukemia: Associations with long-term echocardiographic outcomes." J Clin Oncol. 2012; 30(10): 1042-9.
2011
Asselin, BL; Devidas, M; Wang, C; Pullen, J; Borowitz, MJ; Hutchison, R; Lipshultz, S; Camitta, BM. "Effectiveness of High Dose Methotrexate in T-cell Lymphoblastic Leukemia and Advanced Stage Lymphoblastic Lymphoma: A Randomized Study by the Children's Oncology Group (POG 9404)". Blood. 2011; 118(4): 874-883.
2011
Asselin, BL. "L-Asparaginase for Treatment of Childhood Acute Lymphoblastic Leukemia: What Have We Learned?". Pediatric Blood Cancer. 2011; 57(3): 357-358.
2011
Lipshultz, SE; Miller, TL; Lipsitz, SR; Neuberg, DS; Dahlberg, SE; Colan, SD; Silverman, LB; Henkel, JM; Cushman, LL; Asselin, BL; Clavell, LA; Athale, U; Michon, B; Laverdiere, C; Schorin, MA; Larsen, E; Usmani, N; Sallan, SE, for the Dana-Farber Cancer Institute Acute Lymphoblastic Leukemia Consortium. "Late Cardiac Status in Long-Term Survivors of Childhood High-Risk Acute Lymphoblastic Leukemia 8 Years After Continuous or Bolus Infusion of Doxorubicin: The Dana-Farber Cancer Institute ALL 91-01 Randomized Trial". J Clin Oncol. 2011; .
2011
Kurtzberg J; Asselin B; Bernstein M; Buchanan GR; Pollock BH; and Camitta BM. "Polyethylene glycol-conjugated L-asparaginase versus native L-asparaginase in combination with standard agents for children with acute lymphoblastic leukemia in second bone marrow relapse: A Children's Oncology Group Study (POG 8866)". Journal of Pediatric Hematology Oncology. 2011; 33(8): 610-16.
2011
Vrooman LM, Neuberg DS, Stevenson KE, Asselin BL, Athale UH, Clavell L, Cole PD, Kelly KM, Larsen EC, Laverdiere C, Michon B, Schorin M, Schwartz CL, Cohen HJ, Lipshultz SE, Silverman LB, and Sallan SE. "The low incidence of secondary acute myelogenous leukemia in children and adolescents treated with dexrazoxane for acute lymphoblastic leukemia: A report from the Dana-Farber Cancer Institute ALL Consortium". Eur J Cancer. 2011; 47: 1373-79.
2010
Silverman, LB; Stevenson, K; O'Brien, JE; Asselin, BL; Athale, UH; Clavell, L; Cole, PD; Kelly, K; Laverdiere, C; Michon, B; Schorin, M; Schwartz, CL; Whyte, O'Holleran, E; Neuberg, DS; Cohen, HJ; Sallan, SE. "Long-term results of Dana-Farber Cancer Institute ALL Consortium protocols for children with newly diagnosed acute lymphoblastic leukemia (1981-1995)". Leukemia. 2010; 24: 320-334.
2010
Vrooman, LM; Supko, J; Neuberg, DS; Asselin, BL; Athale, UH, Clavell, L; Kelly, K; Laverdiere, C; Michon, B; Schorin, M; Sallan, SE; Silverman, LB. "Erwinia asparaginase after allergy to E. coli asparaginase in children with acute lymphoblastic leukemia: pharmacodynamics and tolerability." Pediatric Blood and Cancer. 2010; 54: 199-205.
2010
Silverman, LB; Supko, JG; Stevenson, KE; Woodward, C; Vrooman, LM; Neuberg, DS; Asselin, BL; Athale, UH; Cole, PD; Kelly, KM; Laverdiere, C; Michon, B; Schorin, M; Schwartz, CL; O'Brien, JE; Cohen HJ; Sallan, SE. "Intravenous PEG-asparaginase during remission induction in children and adolescents with newly diagnosed acute lymphoblastic leukemia." Blood. 2010; 115(7): 1351-53.
2010
Lipshultz SE; Scully RE; Lipsitz SR; Sallan SE; Silverman LB; Miller TL; Barry EV; Asselin BL; Athale U; Clavell LA; Larsen E; Moghrabi A; Samson Y; Michon B; Schorin MA; Cohen HJ; Neuberg DS; Orav EJ; Colan SD. "Assessment of dexrazoxane as a cardioprotectant in doxorubicin-treated children with high-risk acute lymphoblastic leukemia: long-term follow-up of a prospective, randomized, multicentre trial." Lancet Oncol. 2010; 11: 950-61.
2008
Barry EV, Vrooman LM, Dahlberg SE, Neuberg DS, Asselin BL, Athale UH, Clavell LA, Larsen EC, Moghrabi A, Sanson Y, Schorin MA, Cohen HJ, Lipshultz SE, Sallan SE, and Silverman LB. "Absence of secondary malignant neoplasms in children with high-risk acute lymphoblastic leukemia treated with dexrazoxane." J Clin Oncol. 2008; 26(7): 1106-11.
2007 Feb
Moghrabi A, Levy DE, Asselin BL, Barr R, Clavell L, Hurwitz C, Samson Y, Schorin M, Dalton VK, Lipshultz SE, Neuberg DS, Gelberg RD, Cohen HJ. "Results of the Dana-Farber Cancer Institute ALL Consortium Protocol 95-01 for children with acute lymphoblastic leukemia." Blood First Editioin Paper, prepublished online Sept 26, 2006. DOI 10.1182/blood-206-06-027714. 2007; 109(3): 896-904.
2007
Salzer WL, Devias M, Shuster JJ, Wang C, Chauvenet A, Asselin BL, Camitta BM and Kurtzberg J. "Intensified PEG-L-asparaginase and antimetabolite-based therapy for treatment of higher risk precursor-B acute lymphoblastic leukemia: a report from the Children's Oncology Group." J Pediatr Hematol/Oncol. 2007; 29(6): 369-375.
2007
Avramis VI, Martin-Aragon S, Avramis EV, Asselin BL. "Pharmacoanalytical assays of Erwinia asparaginase (erwinase) and pharmacokinetic results in high-risk acute lymphoblastic leukemia (HR ALL) patients: simulations of erwinase population PK-PD models." Anticancer Res. 2007; 27(4C): 2561-72.
2007
Barry EV, Deangelo DJ, Neuberg DS, Loh MS, Asselin BL, Barr R, Clavell L, Hurwitz C, Moghrabi A, Samson Y, Schorin M, Cohen HJ, Sallan SE and Silverman LB. "Favorable Outcome for Adolescents with Acute Lymphoblastic Leukemia (ALL) Treated on Dana-Farber Cancer Institute (DFCI; Boston, MA) ALL Consortium Protocols." Journal of clinical oncology: official journal of the American Society of Clinical Oncology. 2007; 25(7): 813-9.
2007
Winter SS, Jiang Z, Khawaja H, Griffin T, Devidas M, Asselin BL, and Larsen RS. "Identification of genomic classifiers that distinguish induction failure in T-lineage acute lymphoblastic leukemia: a report from the Children's Oncology Group." Blood. 2007; 110(5): 1429-38.
2005
Basu SK, Fernandez ID, Fisher SG, Asselin BL, and Lyman GH. "Length of stay and morbidity associated with febrile neutropenia among children with cancer." J Clin Oncol. 2005; 23(31): 7958-66.
2004
Lipshultz SE, Nader R, Dalton VM, Levy DE, Silverman LB, Lipsitz SR, Colan SD, Asselin BL, Barr, RD, Clavell LA, Hurwitz CA, Moghrabi A, Samson Y, Schorin MA, Gelber RD and Sallan SE. "The effect of dexrazoxane on myocardial injury in doxorubicin-treated children with acute lymphoblastic leukemia." N Engl J Med. 2004; 351(2): 145-53.
2003
Moghrabi A, Samaon Y, Schorin M, Tarbell NJ, Sallan SE, and Cohen LE. "Height and weight in children treated for acute lymphoblastic leukemia: relationship to CNS treatment." J Clin Oncol. 2003; 21(15): 2953-60.
2003
Goldberg JM, Silverman LB, Levy DE, Dalton VK, Gelber RD, Lehmann L, Cohen HJ, Sallan SE and Asselin BL. "Childhood T-Cell Acute Lymphoblastic Leukemia (ALL): the Dana-Farber Cancer Institute ALL Consortium experience." J Clin Oncol. 2003; 21(19): 3616-22.
2002
LeClerc JM, Billett AL, Gelber RD, Tarbell NJ, Lipton JM, Barr RD, Clavell LA, Asselin BL, Hurwitz CA, Schorin MA, Dalton VK, Declerck L, Cohen HJ and Sallan SE. "Treatment of childhood acute lymphoblastic leukemia: Results of Dana-Farber ALL Consortium Protocol 87-01". J Clin Oncol. 2002; 20(1): 237-46.
2002
Lipshultz SE, Giantris AL, Lipsitz SR, Dalton VK, Asselin BL, Barr RD, Clavell LA, Hurwitz CA, Moghrabi A, Samson Y, Schorin MA, Gelber RD, Sallan SE, and Colan SD. "Doxorubicin administration by continuous infusion is not cardioprotective: The Dana-Farber 91-01 Acute Lymphoblastic Leukemia Protocol". J Clin Oncol. 2002; 20(6): 1677-82.
2001
Silverman LB, Gelber RD, Asselin BL, Barr RD, Clavell LA, Hurwitz CA, Moghrabi A, Samson Y, Schorin MA, Arkin S, Dalton VK, Zou G, Cohen HJ and Sallan SE. "Improved outcome for children with acute lymphoblastic leukemia: Results of Dana-Farber Consortium Protocol 91-01." Blood. 2001; 97(5): 1211-8.
2000
Silverman LB, Declerck L, Gelber RD, Dalton VK, Asselin BL, Barr RD, Clavell LA, Hurwitz CA, Moghrabi A, Samson Y, Schorin MA, Lipton JM, Cohen HJ, Sallan SE. "Results of Dana-Farber Cancer Institute Consortium protocols for children with newly diagnosed acute lymphoblastic leukemia (1981-1995)." Leukemia.. 2000 14(12):2247-56.
1999
Asselin BL, Kreissman S, Coppola DJ, Bernal SD, Leavitt PR, Gelber RD, Sallan SE, Cohen HJ. "Prognostic significance of early response to a single dose of asparaginase in childhood acute lymphoblastic leukemia." Journal of pediatric hematology/oncology.. 1999 21(1):6-12.
1999
Asselin BL. "The three asparaginases. Comparative pharmacology and optimal use in childhood leukemia." Advances in experimental medicine and biology. 1999 457:621-9.
1998 Jan
Giantris A, Abdurrahman L, Hinkle A, Asselin BL, Lipshultz S. "Anthracycline Induced Cardiotoxicity". Critical Reviews in Oncology-Hematology. 1998; 27: 53-68. Link
1998
Graham ML, Asselin, BL, Herndon JE, III, Casey JR, Chaffee S. Ciocci GH, Daeschner CW, Davis AR, Gold S, Halperin EC, Laughlin MJ, Martin PL, Olson JF, and Kurtzberg J. "Toxicity, pharmacology and feasibility of administration of PEG-L-Asparaginase as consolidation therapy in patients undergoing bone marrow transplantation for acute lymphoblastic leukemia." Bone Marrow Transplantation. 1998; 21(9): 879-85.
1997
Snitzer EL, Fultz PJ, Asselin B. "Magnetic resonance imaging appearance of fibromatosis colli." Magnetic resonance imaging.. 1997 15(7):869-71.
1996 Jun
Asselin BL. "Pegaspargase: A viewpoint". Clin Therapeutics. 1996; 5: 497-498. Link
1996
Korones DN, Buzzard CJ, Asselin BL and Harris JP. "Right atrial thrombi in children with cancer and indwelling catheters." Journal of Pediatrics. 1996; 128(6): 841-6.
1993 Sep
Asselin BL, Whitin JC, Coppola DJ, Rupp IP, Sallan SE, Cohen HJ. "Comparative pharmacokinetic studies of three asparaginase preparations." Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 1993 Sep; 11(9):1780-6.
1992 Mar 13
Asselin BL. "Evaluation of tumor cell heterogeneity based on response to chemotherapy." Clinica chimica acta; international journal of clinical chemistry. 1992 Mar 13; 206(1-2):33-44.
1992
Stephens R, Asselin BL. "Application of the MTT assay to chemosensitivity testing using human leukemic cell lines". Journal Univ Rochester Medical Center. 1992; 3(2).
1991
Asselin BL, Lorenson MY, Whitin JC, Coppola DJ, Kende AS, Blakley RL, Cohen HJ. "Measurement of serum L-asparagine in the presence of L-asparaginase requires the presence of an L-asparaginase inhibitor." Cancer research.. 1991 51(24):6568-73.
1990 Apr
Asselin BL. "Clinical use of intravenous immunoglobulin". Hospital Therapy. 1990; 15(4): 479-439.
1990
Rupp IP*, Asselin BL, Whitin JC, Cohen HJ. "Clearance of L-asparaginase enzyme activity and protein". Journal Univ Rochester Medical Center. 1990; 2(2): 2-5.
1989 Aug 1
Asselin BL, Ryan D, Frantz CN, Bernal SD, Leavitt P, Sallan SE, Cohen HJ. "In vitro and in vivo killing of acute lymphoblastic leukemia cells by L-asparaginase." Cancer research.. 1989 Aug 1; 49(15):4363-8.
1987 Mar
Asselin BL, Lawrence RA. "Maternal disease as a consideration in lactation management." Clinics in perinatology. 1987 Mar; 14(1):71-87.
0
Vrooman, ML; Neuberg, DS; Stevenson, KE; Asselin, BL; Athale, UH; Clavell, L; Cole, PD; Kelly, KM; Laverdiere, C; Michon, B; Schorin, M; Schwartz, CL; Cohen, HJ; Lipshultz, SE; Silverman, LB; Sallan, SE. "The Rarity of Second Malignant Neoplasms Associated with Dexrazoxane in Children Treated for Acute Lymphoblastic Leukemia; a Report from the Dana-Farber Cancer Institute ALL Consortium". Journal of Clinical Oncology. .
0
Vrooman, ML; Neuberg, DS; Stevenson, KE; Asselin, BL; Athale, UH; Clavell, L; Cole, PD; Kelly, KM; Laverdiere, C; Michon, B; Schorin, M; Schwartz, CL; Cohen, HJ; Lipshultz, SE; Silverman, LB; Sallan, SE. "The Rarity of Second Malignant Neoplasms Associated with Dexrazoxane in Children Treated for Acute Lymphoblastic Leukemia". Journal of Clinical Oncology. .

Books

2011
BL Asselin. ""Epidemiology of Childhood and Adolescent Cancer" in Nelson Textbook of Pediatrics".". Nelson Textbook of Pediatrics. ed. Kliegman RM, Behrman RE, Stanton BF, Schor N, and St.Geme J.. Philadelphia: WB Saunders, 2011.
2010
Asselin, BL; Hudson, M; Constine, LS. "Pediatric Leukemias and Lymphomas". Textbook of Radiation Oncology. Leibel S. Phillips. Philadelphia: WB Saunders, 2010.
2010
Kliegman RM, Behrman RE, Stanton BF, Schor N, and St. Geme J. "Epidemiology of Childhood and Adolescent Cancer". Nelson Textbook of Pediatrics, 19th ed.. Philadelphia: WB Saunders, 2010.
2007
Asselin BL.. "Histiocytosis Syndromes". Pediatric Clinical Advisor. Garfunkel LC, Christy C, Kaczorowski J. St. Louis, MO: CV. Mosby, Inc, 2007.
2007
Asselin BL. "Non-Hodgkin's Lymphoma". Pediatric Clinical Advisor. Garfunkel LC, Christy C, Kaczorowski J. St. Louis, MO: CV Mosby Inc., 2007.
2007
Hudson M, Asselin BL, Constine LS. "Lymphomas in Children". Principles and Practice of Radiation Oncology. Perez, Brady, Halperin. Philadelphia: Lippincott, Williams and Wilkins, Inc., 2007.
2004
Hudson M, Asselin BL, Mandell LR, Constine LS. ""Lymphomas in Children"". Principles and Practice of Radiation Oncology. Perez, Brady, Halperin. Philadelphia, PA: Lippincott Williams & Wilkins, 2004.
2004
Asselin BL, Hudson M, Mandell L, Constine LS. ""Pediatric Leukemias and Lymphomas"". Textbook of Radiation Oncology. Leibel S, Phillips T. Philadelphia, PA: WB Saunders, 2004.
2003
Asselin BL, Kurtzberg J. ""Asparaginase"". Treatment of Acute Leukemias: New Directions for Clinical Research. Pui C-H. : The Humana Press, Inc., 2003.
2001
Asselin BL. ""Non-Hodgkin's Lymphoma"". Pediatric Clinical Advisor. Garfunkel LC, Christy C, Kaczorowski J. St. Louis, MO: C.V. Mosby, Inc., 2001.
2001
Asselin BL. ""The Leukemias of Childhood"". Primary Pediatric Care. R. Hoekelman, et al. St. Louis, MO: C.V. Mosby Co., 2001.
2000
Peacock J; Asselin BL (medical consultant). Leukemia: Perspectives on disease and illness. Mankato, MN: Capstone Press, 2000.
1998
Asselin BL. ""Hemolytic Anemia in Children"". Current Pediatric Therapy. Burg FD, Ingelfinger JR, Polin RA, Wald ER. : W.B. Saunders Co., 1998.
1997
Asselin BL. ""The Leukemias of Childhood"". Primary Pediatric Care. R. Hoekelman, et al. St. Louis, MO: C.V. Mosby Co., 1997.
1997
Asselin BL. ""Laboratory Monitoring of Asparaginase Therapy"". Acute Lymphoblastic Leukemia- The Cutting Edge. Poplack D. Dallas, TX: Baylor-Sammons Cancer Center, 1997.
1997
Silverman LB, Asselin BL, Sallan SE. ""Treatment for Childhood Acute Lymphoblastic Leukemia: The Dana-Farber Cancer Institute Consortium Experience"". Acute Lymphoblastic Leukemia -The Cutting Edge. Poplack D. Dallas, TX: Baylor-Sammons Cancer Center, 1997.
1994
Asselin BL, Segel GB.. ""Nonimmune Hemolytic Anemia"". Conn's Current Therapy. R. Rakel. : W.B. Saunders Co., 1994.
1992
Asselin BL. ""The Leukemias of Childhood"". Primary Pediatric Care. R. Hoekelman, et al. St. Louis, MO: C.V. Mosby Co., 1992.