Patricia J. Simpson-Haidaris, Ph.D.

Patricia J. Simpson-Haidaris, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 610
Rochester, NY 14642

Appointment: (585) 275-URMC (8762)

Patient Care Bio

My major academic commitment is to serve as mentor to undergraduate, graduate, medical and resident fellows wishing to pursue academic research with the goal of fostering their desires to contribute to the scholarship and knowledge of the biomedical research disciplines and health professions. I have teaching commitments in both Pathology and Microbiology & Immunology at the graduate student level at the University of Rochester. Furthermore, my commitment to mentored-training is evidenced by my service since 2001 as a reviewer on the NHLBI Special Emphasis panels for mentored training awards including the K08, K22, K23, K24, K25 and K99/R00 award mechanisms, and since 2005 as a Scientist Reviewer for Department of Defense and Komen Foundation pre-doctoral and post-doctoral training grant awards.



My research program at the University of Rochester includes both independent investigations and collaborative interactions with faculty members of the Departments of Pediatrics and Microbiology & Immunology on the pathogenic mechanisms of Pneumocystis carinii pneumonia and the host inflammatory response and wound repair in response to Photodynamic therapy of Candida infections, and in the Departments of Medicine and Biochemistry & Biophysics on the interactions of fibrinogen and fibrin at the vessel wall and the extracellular matrix. Additional collaborations with colleagues in the Cancer Center and Bioengineering are based on the role of fibrinogen in breast and prostate cancer, in the Department of Pharmacology and Physiology and the Cardiovascular Research Institute on studies examining cellular responses to heparin binding growth factors, fibrinogen, fibronectin and heparan sulfate proteoglycans in the extracellular matrix, in the Center for Oral Biology on the pathogenesis of infective endocarditis caused by Streptococcus mutans invasion of human coronary artery endothelial cells, and in the Infectious Disease Division on the the direct and indirect effects of Dengue virus infection of the vascular endothelium and the molecular pathways that may contribute to the vascular leakage syndrome associated with dengue hemorrhagic fever/dengue shock syndrome.

Awards & Honors (Local)

Miles Inc., Post-doctoral Fellowship (Salary and Supplies) 1981
American Society for Microbiology Garner Award for Oral Presentation 1980
Miles Inc., Pre-doctoral Fellowship (Stipend and Tuition) 1979 - 1981
Indiana University Merit Scholarship 1970 - 1973

Current Appointments

Associate Professor - Department of Medicine, Hematology/Oncology (SMD) - Primary

Education

Certificate | Deaf Studies | Rochester Institute of Technology2000
PhD | Microbiology | University of Notre Dame1981
MS | Microbiology | University of Notre Dame1980
BA, double major | Chemistry & Biology | Indiana University1973

Post-Doctoral Training & Residency

Post-doctoral Fellow. Dept of Microbiology and Immunology, University of North Carolina. Research Mentor: Kenneth Bott, Ph.D.: "Molecular cloning and expression in prokaryotes. 0
Graduate Research Assistant, Dept of Microbiology, University of Notre Dame. Dissertation research performed under the direction of Dr. Charles Kulpa. Ph.D. Thesis: "Characterization and evaluation of large unilamellar liposomes as carriers of synthetic, single-stranded polyribonucleotides to affect RNA virus replication in culture. 1981
Associate Development Scientist: Miles, Inc., Ames Division. Developed and implemented quality assurance control systems to define quality of new products from raw materials through in-process production, finished product and clinical trials following GMP, GLP and FDA regulations for new clinical diagnostic products in immunochemistry test systems. 1979
Assistant Development Scientist: Miles Inc., Ames Division. Developed quality assurance control systems to define quality of new products for thyroid function, hepatitis B and urine chemistry test systems. Elkhart, IN 46515 1976