Robert A. Gross, M.D., Ph.D.

Robert A. Gross, M.D., Ph.D.

Contact Information

919 Westfall Rd, Clinton Crossings Bldg C, Suite 220
Rochester, NY 14618

Fax: (585) 756-2311
Administrative: (585) 275-6412
Office: (585) 275-6412

Professional Bio

Robert A. Gross MD, PhD, FAAN graduated from Harvard College with an AB in Biology, summa cum laude, in 1975. He entered the Medical Scientist Training Program at Washington University, St. Louis, where he earned both the MD and PhD (Pharmacology) degrees (1981). He received the Cowdry Prize in Histology. He interned in Medicine at Jewish Hospital in St. Louis and his residency in Neurology was at the Massachusetts General Hospital, where he served as Chief Resident. Faculty positions followed at the University of Michigan (1985-1991) and the University of Minnesota (1991-1994). Dr. Gross joined the faculty of the University of Rochester Medical Center (URMC) in 1994.

He sees patients in the Strong Epilepsy Center, with a particular interest in the pharmacology of anti-seizure drugs.

Research interests have centered on the regulation of neuronal ion channel activity by pharmacological agents and neurotransmitters and, more recently, the regulation of hippocampal neurogenesis by seizures and by chemotherapeutic drugs (as a mechanism of 'chemobrain'). Collaborative studies include investigations of the role of inflammation in epileptogenesis and various clinical trials, including participation in a multi-center task force to design trials to compare brand to generic AEDs. He was the recipient of the S. Weir Mitchell Award of the American Academy of Neurology (AAN) in 1988.

Dr. Gross' educational efforts are diverse. He is a former director of the interdepartmental Graduate Program in Neuroscience at the University of Rochester. He is the founding and current Director of the Academic Research Track, an innovative curriculum for medical students that prepares them for a year-out experience in medical research, often concurrent with Masters degree preparation. This program is funded by URMC's Clinical and Translational Science Award and he is a member of the grant's Educational and Evaluation Directorate. He serves on the design committee for the medical student course "Mind, Brain and Behavior" for which he provides 9 hours of lecture in neuropharmacology. He is the Director of a novel basic science course for fourth year medical students, the month-long "Process of Discovery," in which they design cutting-edge research programs to effect changes in clinical care over a decade. He teaches in AAN Annual Meeting courses and was responsible for the "Neuropharmacology" section of the Resident Basic Science Curriculum.

He has served as an Associate Editor of Neurology® since 2001, two of which were as Deputy Editor. He was appointed Editor-in-Chief in 2010.

He is a fellow of the AAN, and a member of the Society for Neuroscience, the American Neurological Association and the American Epilepsy Society. Dr. Gross is active in the Epilepsy Foundation of the Rochester, Syracuse and Binghamton regions, having served as a Chair of the Board of Directors.

He has appeared on the PBS program "Second Opinion" and on local radio shows on the topic of epilepsy.

Awards & Honors (Local)

Buswell Fellow | University of Rochester 1997
S. Weir Mitchell Award | American Academy of Neurology 1987
Irwin S. Levy Prize in Neurology | Washington University 1981
Election to Alpha Omega Alpha | Washington University 1981
Cowdry Prize in Microscopic Anatomy | Washington University 1976
A.B. in Biology, summa cum laude | Harvard College 1975

Recent Journal Articles

Showing the 5 most recent journal articles. 72 available »

2015 Apr
Gewandter JS, Smith SM, McKeown A, Edwards K, Narula A, Pawlowski JR, Rothstein D, Desjardins PJ, Dworkin SF, Gross RA, Ohrbach R, Rappaport BA, Sessle BJ, Turk DC, Dworkin RH. "Reporting of adverse events and statistical details of efficacy estimates in randomized clinical trials of pain in temporomandibular disorders: Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks systematic review." The Journal of the American Dental Association. 2015 Apr; 146(4):246-54.e6.
2015 Jan 6
Baskin PK, Gross RA. "Tools for readers: Getting the most from the Neurology electronic platforms." Neurology. 2015 Jan 6; 84(1):11-2.
2015 Jan
Gewandter JS, McKeown A, McDermott MP, Dworkin JD, Smith SM, Gross RA, Hunsinger M, Lin AH, Rappaport BA, Rice AS, Rowbotham MC, Williams MR, Turk DC, Dworkin RH. "Data interpretation in analgesic clinical trials with statistically nonsignificant primary analyses: an ACTTION systematic review." The journal of pain : official journal of the American Pain Society. 2015 Jan; 16(1):3-10. Epub 2014 Oct 23.
2014 Jul 11
Jakob R, Beutner G, Sharma VK, Duan Y, Gross RA, Hurst S, Jhun BS, O-Uchi J, Sheu SS. "Molecular and functional identification of a mitochondrial ryanodine receptor in neurons." Neuroscience letters. 2014 Jul 11; 575:7-12. Epub 2014 May 23.
2014 Jun
Hunsinger M, Smith SM, McKeown A, Parkhurst M, Gross RA, Lin AH, McDermott MP, Rappaport BA, Turk DC, Dworkin RH. "Disclosure of authorship contributions in analgesic clinical trials and related publications: ACTTION systematic review and recommendations." Pain. 2014 Jun; 155(6):1059-63. Epub 2013 Dec 12.

Current Appointments

Professor - Department of Neurology, Epilepsy (SMD) - Primary


Neurology - American Board of Psychiatry and Neurology


MD | Medicine | Washington U Medical Center1981
PhD | Pharmacology | Washington U Medical Center1981
AB | Biology | Harvard College1975

Post-Doctoral Training & Residency

Residency in Neurology at Massachusetts General Hospital07/01/1982 - 06/60/1985
Internship in Internal Medicine at Washington University School of Medicine07/01/1981 - 06/30/1982