Chawnshang Chang, Ph.D.

Chawnshang Chang, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 626
Rochester, NY 14642

Office: (585) 275-9994
Fax: (585) 756-4133

Journal Articles

Showing all 273 journal articles available.

2014 Sep 19
Park SS, Kim SJ, Choi H, Chang C, Kim E. "TR4 promotes fatty acid synthesis in 3T3-L1 adipocytes by activation of pyruvate carboxylase expression." FEBS letters. 2014 Sep 19; Epub 2014 Sep 19.
2010 Jun 24
Niu Y, Chang TM, Yeh S, Ma WL, Wang YZ, Chang C. "Differential androgen receptor signals in different cells explain why androgen-deprivation therapy of prostate cancer fails." Oncogene. 2010 Jun 24; 29(25):3593-604. Epub 2010 May 03.
2010 Feb 1
Shyr CR, Tsai MY, Yeh S, Kang HY, Chang YC, Wong PL, Huang CC, Huang KE, Chang C. "Tumor suppressor PAX6 functions as androgen receptor co-repressor to inhibit prostate cancer growth." The Prostate. 2010 Feb 1; 70(2):190-9.
2009 Oct
Liu NC, Lin WJ, Yu IC, Lin HY, Liu S, Lee YF, Chang C. "Activation of TR4 orphan nuclear receptor gene promoter by cAMP/PKA and C/EBP signaling." Endocrine. 2009 Oct; 36(2):211-7. Epub 2009 Jul 18.
2009 Aug 11
Xie S, Lee YF, Kim E, Chen LM, Ni J, Fang LY, Liu S, Lin SJ, Abe JI, Berk B, Ho FM, Chang C. "TR4 nuclear receptor functions as a fatty acid sensor to modulate CD36 expression and foam cell formation." Proceedings of the National Academy of Sciences of the United States of America. 2009 Aug 11; 106(32):13353-8. Epub 2009 Jul 28.
2009 Aug
Zhang L, Altuwaijri S, Deng F, Chen L, Lal P, Bhanot UK, Korets R, Wenske S, Lilja HG, Chang C, Scher HI, Gerald WL. "NF-kappaB regulates androgen receptor expression and prostate cancer growth." The American journal of pathology. 2009 Aug; 175(2):489-99. Epub 2009 Jul 23.
2009 Jul
Kang HY, Huang HY, Hsieh CY, Li CF, Shyr CR, Tsai MY, Chang C, Chuang YC, Huang KE. "Activin A enhances prostate cancer cell migration through activation of androgen receptor and is overexpressed in metastatic prostate cancer." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2009 Jul; 24(7):1180-93.
2009 May 11
Chuang KH, Altuwaijri S, Li G, Lai JJ, Chu CY, Lai KP, Lin HY, Hsu JW, Keng P, Wu MC, Chang C. "Neutropenia with impaired host defense against microbial infection in mice lacking androgen receptor." The Journal of experimental medicine. 2009 May 11; 206(5):1181-99. Epub 2009 May 04.
2009 May
Shyr CR, Kang HY, Tsai MY, Liu NC, Ku PY, Huang KE, Chang C. "Roles of testicular orphan nuclear receptors 2 and 4 in early embryonic development and embryonic stem cells." Endocrinology. 2009 May; 150(5):2454-62. Epub 2009 Jan 08.
2009 Apr
Altuwaijri S, Chuang KH, Lai KP, Lai JJ, Lin HY, Young FM, Bottaro A, Tsai MY, Zeng WP, Chang HC, Yeh S, Chang C. "Susceptibility to autoimmunity and B cell resistance to apoptosis in mice lacking androgen receptor in B cells." Molecular endocrinology. 2009 Apr; 23(4):444-53. Epub 2009 Jan 22.
2009 Apr
Wang RS, Yeh S, Tzeng CR, Chang C. "Androgen receptor roles in spermatogenesis and fertility: lessons from testicular cell-specific androgen receptor knockout mice." Endocrine reviews. 2009 Apr; 30(2):119-32. Epub 2009 Jan 27.
2009 Jan
Chen M, Hsu I, Wolfe A, Radovick S, Huang K, Yu S, Chang C, Messing EM, Yeh S. "Defects of prostate development and reproductive system in the estrogen receptor-alpha null male mice." Endocrinology. 2009 Jan; 150(1):251-9. Epub 2008 Aug 28.
2009 Jan
Chen M, Wolfe A, Wang X, Chang C, Yeh S, Radovick S. "Generation and characterization of a complete null estrogen receptor alpha mouse using Cre/LoxP technology." Molecular and cellular biochemistry. 2009 Jan; 321(1-2):145-53. Epub 2008 Oct 25.
2009 Jan
Yu SQ, Lai KP, Xia SJ, Chang HC, Chang C, Yeh S. "The diverse and contrasting effects of using human prostate cancer cell lines to study androgen receptor roles in prostate cancer." Asian journal of andrology. 2009 Jan; 11(1):39-48. Epub 2008 Dec 22.
2009
Lai JJ, Lai KP, Chuang KH, Chang P, Yu IC, Lin WJ, Chang C. "Monocyte/macrophage androgen receptor suppresses cutaneous wound healing in mice by enhancing local TNF-alpha expression." The Journal of clinical investigation. 2009 119(12):3739-51. Epub 2009 Nov 09.
2008 Sep 1
Niu Y, Yeh S, Miyamoto H, Li G, Altuwaijri S, Yuan J, Han R, Ma T, Kuo HC, Chang C. "Tissue prostate-specific antigen facilitates refractory prostate tumor progression via enhancing ARA70-regulated androgen receptor transactivation." Cancer research. 2008 Sep 1; 68(17):7110-9.
2008 Sep
Ting HJ, Chang C. "Actin associated proteins function as androgen receptor coregulators: an implication of androgen receptor's roles in skeletal muscle." The Journal of steroid biochemistry and molecular biology. 2008 Sep; 111(3-5):157-63. Epub 2008 Jun 11.
2008 Sep
Ma WL, Ma CL, Hsu CL, Wu MH, Wu CT, Wu CC, Lai JJ, Jou YS, Chen CW, Yeh S, Chang C. "Androgen receptor is a new potential therapeutic target for the treatment of hepatocellular carcinoma." Gastroenterology. 2008 Sep; 135(3):947-55, 955.e1-5. Epub 2008 May 22.
2008 Aug 26
Niu Y, Altuwaijri S, Yeh S, Lai KP, Yu S, Chuang KH, Huang SP, Lardy H, Chang C. "Targeting the stromal androgen receptor in primary prostate tumors at earlier stages." Proceedings of the National Academy of Sciences of the United States of America. 2008 Aug 26; 105(34):12188-93. Epub 2008 Aug 22.
2008 Aug 26
Niu Y, Altuwaijri S, Lai KP, Wu CT, Ricke WA, Messing EM, Yao J, Yeh S, Chang C. "Androgen receptor is a tumor suppressor and proliferator in prostate cancer." Proceedings of the National Academy of Sciences of the United States of America. 2008 Aug 26; 105(34):12182-7. Epub 2008 Aug 22.
2008 Jul 1
Cai Y, Lee YF, Li G, Liu S, Bao BY, Huang J, Hsu CL, Chang C. "A new prostate cancer therapeutic approach: combination of androgen ablation with COX-2 inhibitor." International journal of cancer. Journal international du cancer. 2008 Jul 1; 123(1):195-201.
2008 Jul
Li G, Lee YF, Liu S, Cai Y, Xie S, Liu NC, Bao BY, Chen Z, Chang C. "Oxidative stress stimulates testicular orphan receptor 4 through forkhead transcription factor forkhead box O3a." Endocrinology. 2008 Jul; 149(7):3490-9. Epub 2008 Apr 03.
2008 Jun
Lin HY, Yu IC, Wang RS, Chen YT, Liu NC, Altuwaijri S, Hsu CL, Ma WL, Jokinen J, Sparks JD, Yeh S, Chang C. "Increased hepatic steatosis and insulin resistance in mice lacking hepatic androgen receptor." Hepatology : official journal of the American Association for the Study of Liver Diseases. 2008 Jun; 47(6):1924-35.
2008 May
Yu IC, Lin HY, Liu NC, Wang RS, Sparks JD, Yeh S, Chang C. "Hyperleptinemia without obesity in male mice lacking androgen receptor in adipose tissue." Endocrinology. 2008 May; 149(5):2361-8. Epub 2008 Feb 14.
2008 Apr
Chen LM, Wang RS, Lee YF, Liu NC, Chang YJ, Wu CC, Xie S, Hung YC, Chang C. "Subfertility with defective folliculogenesis in female mice lacking testicular orphan nuclear receptor 4." Molecular endocrinology. 2008 Apr; 22(4):858-67. Epub 2008 Jan 03.
2008
Chen YT, Collins LL, Chang SS, Chang C. "The roles of testicular orphan nuclear receptor 4 (TR4) in cerebellar development." Cerebellum (London, England). 2008 7(1):9-17.
2008
Kang HY, Shyr CR, Huang CK, Tsai MY, Orimo H, Lin PC, Chang C, Huang KE. "Altered TNSALP expression and phosphate regulation contribute to reduced mineralization in mice lacking androgen receptor." Molecular and cellular biology. 2008 28(24):7354-67. Epub 2008 Oct 06.
2007 Nov 15
Hamalainen-Laanaya HK, Kobie JJ, Chang C, Zeng WP. "Temporal and spatial changes of histone 3 K4 dimethylation at the IFN-gamma gene during Th1 and Th2 cell differentiation." The Journal of immunology : official journal of the American Association of Immunologists. 2007 Nov 15; 179(10):6410-5.
2007 Sep 21
Kim E, Ma WL, Lin DL, Inui S, Chen YL, Chang C. "TR4 orphan nuclear receptor functions as an apoptosis modulator via regulation of Bcl-2 gene expression." Biochemical and biophysical research communications. 2007 Sep 21; 361(2):323-8. Epub 2007 Jul 10.
2007 Sep 7
Chen YT, Collins LL, Uno H, Chou SM, Meshul CK, Chang SS, Chang C. "Abnormal cerebellar cytoarchitecture and impaired inhibitory signaling in adult mice lacking TR4 orphan nuclear receptor." Brain research. 2007 Sep 7; 1168:72-82. Epub 2007 Jul 17.
2007 Aug
Xu Q, Lin HY, Yeh SD, Yu IC, Wang RS, Chen YT, Zhang C, Altuwaijri S, Chen LM, Chuang KH, Chiang HS, Yeh S, Chang C. "Infertility with defective spermatogenesis and steroidogenesis in male mice lacking androgen receptor in Leydig cells." Endocrine. 2007 Aug; 32(1):96-106. Epub 2007 Oct 23.
2007 Jul 31
Wu CT, Altuwaijri S, Ricke WA, Huang SP, Yeh S, Zhang C, Niu Y, Tsai MY, Chang C. "Increased prostate cell proliferation and loss of cell differentiation in mice lacking prostate epithelial androgen receptor." Proceedings of the National Academy of Sciences of the United States of America. 2007 Jul 31; 104(31):12679-84. Epub 2007 Jul 25.
2007 Jul 5
Zheng Y, Chen WL, Ma WL, Chang C, Ou JH. "Enhancement of gene transactivation activity of androgen receptor by hepatitis B virus X protein." Virology. 2007 Jul 5; 363(2):454-61. Epub 2007 Feb 28.
2007 Apr 4
Miyamoto H, Yang Z, Chen YT, Ishiguro H, Uemura H, Kubota Y, Nagashima Y, Chang YJ, Hu YC, Tsai MY, Yeh S, Messing EM, Chang C. "Promotion of bladder cancer development and progression by androgen receptor signals." Journal of the National Cancer Institute. 2007 Apr 4; 99(7):558-68.
2007 Apr
Zhang Y, Chen YT, Xie S, Wang L, Lee YF, Chang SS, Chang C. "Loss of testicular orphan receptor 4 impairs normal myelination in mouse forebrain." Molecular endocrinology. 2007 Apr; 21(4):908-20. Epub 2007 Jan 16.
2007 Mar
Yang Z, Chang YJ, Miyamoto H, Yeh S, Yao JL, di Sant'Agnese PA, Tsai MY, Chang C. "Suppression of androgen receptor transactivation and prostate cancer cell growth by heterogeneous nuclear ribonucleoprotein A1 via interaction with androgen receptor coregulator ARA54." Endocrinology. 2007 Mar; 148(3):1340-9. Epub 2006 Nov 16.
2007 Mar
Yang Z, Chang YJ, Yu IC, Yeh S, Wu CC, Miyamoto H, Merry DE, Sobue G, Chen LM, Chang SS, Chang C. "ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptor." Nature medicine. 2007 Mar; 13(3):348-53. Epub 2007 Mar 04.
2007 Mar
Altuwaijri S, Wu CC, Niu YJ, Mizokami A, Chang HC, Chang C. "Expression of human AR cDNA driven by its own promoter results in mild promotion, but not suppression, of growth in human prostate cancer PC-3 cells." Asian journal of andrology. 2007 Mar; 9(2):181-8.
2007 Feb
Yang Z, Chang YJ, Miyamoto H, Ni J, Niu Y, Chen Z, Chen YL, Yao JL, di Sant'Agnese PA, Chang C. "Transgelin functions as a suppressor via inhibition of ARA54-enhanced androgen receptor transactivation and prostate cancer cell growth." Molecular endocrinology. 2007 Feb; 21(2):343-58. Epub 2006 Nov 02.
2007
Zhao X, Zheng B, Huang Y, Yang D, Katzman S, Chang C, Fowell D, Zeng WP. "Interaction between GATA-3 and the transcriptional coregulator Pias1 is important for the regulation of Th2 immune responses." The Journal of immunology : official journal of the American Association of Immunologists. 2007 179(12):8297-304.
2007
Yu SF, Cheng TT, Hsu YH, Lai HM, Chen YC, Chiu CK, Lin KM, Chang C, Chen CJ, Kang HY. "Association of tri-nucleotide (CAG and GGC) repeat polymorphism of androgen receptor gene in Taiwanese women with refractory or remission rheumatoid arthritis." Clinical rheumatology. 2007 26(12):2051-8. Epub 2007 Apr 13.
2007
Liu NC, Lin WJ, Kim E, Collins LL, Lin HY, Yu IC, Sparks JD, Chen LM, Lee YF, Chang C. "Loss of TR4 orphan nuclear receptor reduces phosphoenolpyruvate carboxykinase-mediated gluconeogenesis." Diabetes. 2007 56(12):2901-9. Epub 2007 Sep 07.
2006 Nov 21
Zhang C, Yeh S, Chen YT, Wu CC, Chuang KH, Lin HY, Wang RS, Chang YJ, Mendis-Handagama C, Hu L, Lardy H, Chang C. "Oligozoospermia with normal fertility in male mice lacking the androgen receptor in testis peritubular myoid cells." Proceedings of the National Academy of Sciences of the United States of America. 2006 Nov 21; 103(47):17718-23. Epub 2006 Nov 09.
2006 Sep 1
Marwah P, Marwah A, Lardy HA, Miyamoto H, Chang C. "C19-steroids as androgen receptor modulators: design, discovery, and structure-activity relationship of new steroidal androgen receptor antagonists." Bioorganic & medicinal chemistry. 2006 Sep 1; 14(17):5933-47. Epub 2006 Jun 08.
2006 Mar 10
Mu X, Yang L, Chang C. "Stage dependent and androgen inductive expression of orphan receptor TR4 in rat testis." Biochemical and biophysical research communications. 2006 Mar 10; 341(2):464-9. Epub 2006 Jan 11.
2006
Tsai MY, Yeh SD, Wang RS, Yeh S, Zhang C, Lin HY, Tzeng CR, Chang C. "Differential effects of spermatogenesis and fertility in mice lacking androgen receptor in individual testis cells." Proceedings of the National Academy of Sciences of the United States of America. 2006 103(50):18975-80. Epub 2006 Dec 01.
2006
Chen, CY.; Collins, L.; Uno, H.; Chou, SM.; Meshul, CK.; Chang, SS.; and Chang, C. "Abnormal Cerebellar Cytoarchitecture with Impaired Cerebellar Inhibitory Circuit in Adult Mice Lacking Testicular Orphan Nuclear Receptor 4". MCB. 2006; . Link
2006
Lee, YL.; Liu, NC.; Liu, S.; Wang, RS.; Ho, HC.; Yan, SJ.; Li, G.; Chen, LM.; Lin, WJ.; Puzas, E.; and Chang, C. "Premature aging like syndromes and impaired genomic stability maintenance in mice lacking TR4 orphan nuclear receptor". Nature. 2006; . Link
2006
Liu, NC.; Lin, WJ.; Lee, YF.; Kim, E.; Collins, L.; Lin, HY.; Sparks, JD.; Hanson, RW.; Chen, LM.; and Chang, C. "Hypoglycemia and impaired hepatic glucose production in mice lacking TR4 orphan nuclear receptor." Cell Metabolism. 2006; .
2006
Yang , Z.; Chang, YJ.; Yu, IC.; Miyamoto, H.; Wu, CC.; Yeh, S.; Merry, DE.; Sobue, G.; Chen, LM,; and Chang, C. "Curcumin derivative ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptor aggregation and restoration of VEGF164 expression". Nature Medicine. 2006; . Link
2006
Wang RS, Yeh S, Chen LM, Lin HY, Zhang C, Ni J, Wu CC, di Sant'Agnese PA, deMesy-Bentley KL, Tzeng CR, Chang C. "Androgen receptor in sertoli cell is essential for germ cell nursery and junctional complex formation in mouse testes." Endocrinology. 2006 147(12):5624-33. Epub 2006 Sep 14.
2005 Sep 30
Yang L, Xie S, Jamaluddin MS, Altuwaijri S, Ni J, Kim E, Chen YT, Hu YC, Wang L, Chuang KH, Wu CT, Chang C. "Induction of androgen receptor expression by phosphatidylinositol 3-kinase/Akt downstream substrate, FOXO3a, and their roles in apoptosis of LNCaP prostate cancer cells." The Journal of biological chemistry. 2005 Sep 30; 280(39):33558-65. Epub 2005 Aug 01.
2005 Sep
Miyamoto H, Altuwaijri S, Cai Y, Messing EM, Chang C. "Inhibition of the Akt, cyclooxygenase-2, and matrix metalloproteinase-9 pathways in combination with androgen deprivation therapy: potential therapeutic approaches for prostate cancer." Molecular carcinogenesis. 2005 Sep; 44(1):1-10.
2005 Jun
Lin HY, Xu Q, Yeh S, Wang RS, Sparks JD, Chang C. "Insulin and leptin resistance with hyperleptinemia in mice lacking androgen receptor." Diabetes. 2005 Jun; 54(6):1717-25.
2005 May 1
Wang L, Hsu CL, Chang C. "Androgen receptor corepressors: an overview." The Prostate. 2005 May 1; 63(2):117-30.
2005 May
Chuang KH, Lee YF, Lin WJ, Chu CY, Altuwaijri S, Wan YJ, Chang C. "9-cis-retinoic acid inhibits androgen receptor activity through activation of retinoid X receptor." Molecular endocrinology. 2005 May; 19(5):1200-12. Epub 2005 Jan 13.
2005 May
Miyamoto H, Messing EM, Chang C. "Does androgen deprivation improve treatment outcomes in patients with low-risk and intermediate-risk prostate cancer?" Nature clinical practice. Oncology. 2005 May; 2(5):236-7.
2005 Apr
Chen YT, Collins LL, Uno H, Chang C. "Deficits in motor coordination with aberrant cerebellar development in mice lacking testicular orphan nuclear receptor 4." Molecular and cellular biology. 2005 Apr; 25(7):2722-32.
2005 Mar 4
Kim E, Yang Z, Liu NC, Chang C. "Induction of apolipoprotein E expression by TR4 orphan nuclear receptor via 5' proximal promoter region." Biochemical and biophysical research communications. 2005 Mar 4; 328(1):85-90.
2005 Feb
Hsu CL, Chen YL, Ting HJ, Lin WJ, Yang Z, Zhang Y, Wang L, Wu CT, Chang HC, Yeh S, Pimplikar SW, Chang C. "Androgen receptor (AR) NH2- and COOH-terminal interactions result in the differential influences on the AR-mediated transactivation and cell growth." Molecular endocrinology. 2005 Feb; 19(2):350-61. Epub 2004 Oct 28.
2005
Miyamoto H, Marwah P, Marwah A, Yang Z, Chung CY, Altuwaijri S, Chang C, Lardy H. "Identification of steroid derivatives that function as potent antiandrogens." International journal of cancer. Journal international du cancer. 2005 117(5):866-72.
2005
Fujimoto N, Chang C, Nomura M, Matsumoto T. "Can we prevent prostate cancer? Rationale and current status of prostate cancer chemoprevention." Urologia internationalis. 2005 74(4):289-97.
2004 Oct 22
Lee YF, Bao BY, Chang C. "Modulation of the retinoic acid-induced cell apoptosis and differentiation by the human TR4 orphan nuclear receptor." Biochemical and biophysical research communications. 2004 Oct 22; 323(3):876-83.
2004 Oct 19
Collins LL, Lee YF, Heinlein CA, Liu NC, Chen YT, Shyr CR, Meshul CK, Uno H, Platt KA, Chang C. "Growth retardation and abnormal maternal behavior in mice lacking testicular orphan nuclear receptor 4." Proceedings of the National Academy of Sciences of the United States of America. 2004 Oct 19; 101(42):15058-63. Epub 2004 Oct 11.
2004 Oct
Lin HK, Hu YC, Lee DK, Chang C. "Regulation of androgen receptor signaling by PTEN (phosphatase and tensin homolog deleted on chromosome 10) tumor suppressor through distinct mechanisms in prostate cancer cells." Molecular endocrinology. 2004 Oct; 18(10):2409-23. Epub 2004 Jun 17.
2004 Oct
Altuwaijri S, Lee DK, Chuang KH, Ting HJ, Yang Z, Xu Q, Tsai MY, Yeh S, Hanchett LA, Chang HC, Chang C. "Androgen receptor regulates expression of skeletal muscle-specific proteins and muscle cell types." Endocrine. 2004 Oct; 25(1):27-32.
2004 Aug 6
Hu YC, Yeh S, Yeh SD, Sampson ER, Huang J, Li P, Hsu CL, Ting HJ, Lin HK, Wang L, Kim E, Ni J, Chang C. "Functional domain and motif analyses of androgen receptor coregulator ARA70 and its differential expression in prostate cancer." The Journal of biological chemistry. 2004 Aug 6; 279(32):33438-46. Epub 2004 May 27.
2004 Aug 3
Hu YC, Wang PH, Yeh S, Wang RS, Xie C, Xu Q, Zhou X, Chao HT, Tsai MY, Chang C. "Subfertility and defective folliculogenesis in female mice lacking androgen receptor." Proceedings of the National Academy of Sciences of the United States of America. 2004 Aug 3; 101(31):11209-14. Epub 2004 Jul 26.
2004 Jul 30
Wang L, Lin HK, Hu YC, Xie S, Yang L, Chang C. "Suppression of androgen receptor-mediated transactivation and cell growth by the glycogen synthase kinase 3 beta in prostate cells." The Journal of biological chemistry. 2004 Jul 30; 279(31):32444-52. Epub 2004 Jun 03.
2004 Jul
Kang HY, Cho CL, Huang KL, Wang JC, Hu YC, Lin HK, Chang C, Huang KE. "Nongenomic androgen activation of phosphatidylinositol 3-kinase/Akt signaling pathway in MC3T3-E1 osteoblasts." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2004 Jul; 19(7):1181-90. Epub 2004 Mar 08.
2004 Jul
Mu X, Lee YF, Liu NC, Chen YT, Kim E, Shyr CR, Chang C. "Targeted inactivation of testicular nuclear orphan receptor 4 delays and disrupts late meiotic prophase and subsequent meiotic divisions of spermatogenesis." Molecular and cellular biology. 2004 Jul; 24(13):5887-99.
2004 Jun 25
Ting HJ, Hu YC, Chang C. "Actin monomer enhances supervillin-modulated androgen receptor transactivation." Biochemical and biophysical research communications. 2004 Jun 25; 319(2):393-6.
2004 Jun 15
Xie S, Lin HK, Ni J, Yang L, Wang L, di Sant'Agnese PA, Chang C. "Regulation of interleukin-6-mediated PI3K activation and neuroendocrine differentiation by androgen signaling in prostate cancer LNCaP cells." The Prostate. 2004 Jun 15; 60(1):61-7.
2004 May 4
Chang C, Chen YT, Yeh SD, Xu Q, Wang RS, Guillou F, Lardy H, Yeh S. "Infertility with defective spermatogenesis and hypotestosteronemia in male mice lacking the androgen receptor in Sertoli cells." Proceedings of the National Academy of Sciences of the United States of America. 2004 May 4; 101(18):6876-81. Epub 2004 Apr 23.
2004 Apr 1
Rahman M, Miyamoto H, Chang C. "Androgen receptor coregulators in prostate cancer: mechanisms and clinical implications." Clinical cancer research : an official journal of the American Association for Cancer Research. 2004 Apr 1; 10(7):2208-19.
2004 Apr
Heinlein CA, Chang C. "Androgen receptor in prostate cancer." Endocrine reviews. 2004 Apr; 25(2):276-308.
2004 Mar 1
Litvinov IV, Chang C, Isaacs JT. "Molecular characterization of the commonly used human androgen receptor expression vector, pSG5-AR." The Prostate. 2004 Mar 1; 58(4):319-24.
2004 Mar
Wang L, Hsu CL, Ni J, Wang PH, Yeh S, Keng P, Chang C. "Human checkpoint protein hRad9 functions as a negative coregulator to repress androgen receptor transactivation in prostate cancer cells." Molecular and cellular biology. 2004 Mar; 24(5):2202-13.
2004 Feb
Zhang Y, Yang Y, Yeh S, Chang C. "ARA67/PAT1 functions as a repressor to suppress androgen receptor transactivation." Molecular and cellular biology. 2004 Feb; 24(3):1044-57.
2004 Jan 30
Yang L, Yeh SD, Xie S, Altuwaijri S, Ni J, Hu YC, Chen YT, Bao BY, Su CH, Chang C. "Androgen suppresses PML protein expression in prostate cancer CWR22R cells." Biochemical and biophysical research communications. 2004 Jan 30; 314(1):69-75.
2004 Jan 1
Miyamoto H, Rahman MM, Chang C. "Molecular basis for the antiandrogen withdrawal syndrome." Journal of cellular biochemistry. 2004 Jan 1; 91(1):3-12.
2004
Miyamoto H, Messing EM, Chang C. "Androgen deprivation therapy for prostate cancer: current status and future prospects." The Prostate. 2004 61(4):332-53.
2004
Wang PH, Chang C. "Androgens and ovarian cancers." European journal of gynaecological oncology. 2004 25(2):157-63.
2003 Nov 21
Kim E, Xie S, Yeh SD, Lee YF, Collins LL, Hu YC, Shyr CR, Mu XM, Liu NC, Chen YT, Wang PH, Chang C. "Disruption of TR4 orphan nuclear receptor reduces the expression of liver apolipoprotein E/C-I/C-II gene cluster." The Journal of biological chemistry. 2003 Nov 21; 278(47):46919-26. Epub 2003 Sep 03.
2003 Nov 17
Ohtsu H, Itokawa H, Xiao Z, Su CY, Shih CC, Chiang T, Chang E, Lee Y, Chiu SY, Chang C, Lee KH. "Antitumor agents 222. Synthesis and anti-androgen activity of new diarylheptanoids." Bioorganic & medicinal chemistry. 2003 Nov 17; 11(23):5083-90.
2003 Nov 1
Altuwaijri S, Lin HK, Chuang KH, Lin WJ, Yeh S, Hanchett LA, Rahman MM, Kang HY, Tsai MY, Zhang Y, Yang L, Chang C. "Interruption of nuclear factor kappaB signaling by the androgen receptor facilitates 12-O-tetradecanoylphorbolacetate-induced apoptosis in androgen-sensitive prostate cancer LNCaP cells." Cancer research. 2003 Nov 1; 63(21):7106-12.
2003 Oct 31
Mu X, Chang C. "TR3 orphan nuclear receptor mediates apoptosis through up-regulating E2F1 in human prostate cancer LNCaP cells." The Journal of biological chemistry. 2003 Oct 31; 278(44):42840-5. Epub 2003 Aug 28.
2003 Oct 1
Mu X, Chang C. "TR2 orphan receptor functions as negative modulator for androgen receptor in prostate cancer cells PC-3." The Prostate. 2003 Oct 1; 57(2):129-33.
2003 Sep
Lee DK, Chang C. "Endocrine mechanisms of disease: Expression and degradation of androgen receptor: mechanism and clinical implication." The Journal of clinical endocrinology and metabolism. 2003 Sep; 88(9):4043-54.
2003 Aug 15
Nishimura K, Ting HJ, Harada Y, Tokizane T, Nonomura N, Kang HY, Chang HC, Yeh S, Miyamoto H, Shin M, Aozasa K, Okuyama A, Chang C. "Modulation of androgen receptor transactivation by gelsolin: a newly identified androgen receptor coregulator." Cancer research. 2003 Aug 15; 63(16):4888-94.
2003 Aug
Lee HJ, Chang C. "Recent advances in androgen receptor action." Cellular and molecular life sciences : CMLS. 2003 Aug; 60(8):1613-22.
2003 Jul
Heinlein CA, Chang C. "Induction and repression of peroxisome proliferator-activated receptor alpha transcription by coregulator ARA70." Endocrine. 2003 Jul; 21(2):139-46.
2003 Jun 27
Hsu CL, Chen YL, Yeh S, Ting HJ, Hu YC, Lin H, Wang X, Chang C. "The use of phage display technique for the isolation of androgen receptor interacting peptides with (F/W)XXL(F/W) and FXXLY new signature motifs." The Journal of biological chemistry. 2003 Jun 27; 278(26):23691-8. Epub 2003 Apr 24.
2003 Jun 6
Yang L, Wang L, Lin HK, Kan PY, Xie S, Tsai MY, Wang PH, Chen YT, Chang C. "Interleukin-6 differentially regulates androgen receptor transactivation via PI3K-Akt, STAT3, and MAPK, three distinct signal pathways in prostate cancer cells." Biochemical and biophysical research communications. 2003 Jun 6; 305(3):462-9.
2003 Jun
Cai Y, Dai T, Ao Y, Konishi T, Chuang KH, Lue Y, Chang C, Wan YJ. "Cytochrome P450 genes are differentially expressed in female and male hepatocyte retinoid X receptor alpha-deficient mice." Endocrinology. 2003 Jun; 144(6):2311-8.
2003 Jun
Kang HY, Tsai MY, Chang C, Huang KE. "Mechanisms and clinical relevance of androgens and androgen receptor actions." Chang Gung medical journal. 2003 Jun; 26(6):388-402.
2003 May 30
Rahman MM, Miyamoto H, Takatera H, Yeh S, Altuwaijri S, Chang C. "Reducing the agonist activity of antiandrogens by a dominant-negative androgen receptor coregulator ARA70 in prostate cancer cells." The Journal of biological chemistry. 2003 May 30; 278(22):19619-26. Epub 2003 Mar 20.
2003 May 9
Yang L, Lin HK, Altuwaijri S, Xie S, Wang L, Chang C. "APPL suppresses androgen receptor transactivation via potentiating Akt activity." The Journal of biological chemistry. 2003 May 9; 278(19):16820-7. Epub 2003 Mar 05.
2003 Apr 29
Rahman MM, Miyamoto H, Lardy H, Chang C. "Inactivation of androgen receptor coregulator ARA55 inhibits androgen receptor activity and agonist effect of antiandrogens in prostate cancer cells." Proceedings of the National Academy of Sciences of the United States of America. 2003 Apr 29; 100(9):5124-9. Epub 2003 Apr 16.
2003 Apr 15
Miyamoto H, Marwah P, Marwah A, Lardy H, Chang C. "3 beta-acetoxyandrost-1,5-diene-17-ethylene ketal functions as a potent antiandrogen with marginal agonist activity." Proceedings of the National Academy of Sciences of the United States of America. 2003 Apr 15; 100(8):4440-4. Epub 2003 Apr 02.
2003 Mar 28
Chey WY, Chang CH, Pan HJ, Chang C, Kim BM, Park IS, Chang TM. "Evidence on the presence of secretin cells in the gastric antral and oxyntic mucosa." Regulatory peptides. 2003 Mar 28; 111(1-3):183-90.
2003 Mar 14
Lin WJ, Li J, Lee YF, Yeh SD, Altuwaijri S, Ou JH, Chang C. "Suppression of hepatitis B virus core promoter by the nuclear orphan receptor TR4." The Journal of biological chemistry. 2003 Mar 14; 278(11):9353-60. Epub 2003 Jan 08.
2003 Feb 28
Yang Y, Wang X, Dong T, Kim E, Lin WJ, Chang C. "Identification of a novel testicular orphan receptor-4 (TR4)-associated protein as repressor for the selective suppression of TR4-mediated transactivation." The Journal of biological chemistry. 2003 Feb 28; 278(9):7709-17. Epub 2002 Dec 16.
2003 Feb 28
Thin TH, Wang L, Kim E, Collins LL, Basavappa R, Chang C. "Isolation and characterization of androgen receptor mutant, AR(M749L), with hypersensitivity to 17-beta estradiol treatment." The Journal of biological chemistry. 2003 Feb 28; 278(9):7699-708. Epub 2002 Dec 23.
2003 Feb 28
Lee DK, Li M, Chang C. "The second largest subunit of RNA polymerase II interacts with and enhances transactivation of androgen receptor." Biochemical and biophysical research communications. 2003 Feb 28; 302(1):162-9.
2003 Feb
Inui S, Lee YF, Chang E, Shyr CR, Chang C. "Differential and bi-directional regulation between TR2/TR4 orphan nuclear receptors and a specific ligand mediated-peroxisome proliferator-activated receptor alpha in human HaCaT keratinocytes." Journal of dermatological science. 2003 Feb; 31(1):65-71.
2003 Jan
Lee DK, Chang C. "Molecular communication between androgen receptor and general transcription machinery." The Journal of steroid biochemistry and molecular biology. 2003 Jan; 84(1):41-9.
2003
Lin HK, Hu YC, Yang L, Altuwaijri S, Chen YT, Kang HY, Chang C. "Suppression versus induction of androgen receptor functions by the phosphatidylinositol 3-kinase/Akt pathway in prostate cancer LNCaP cells with different passage numbers." The Journal of biological chemistry. 2003 278(51):50902-7. Epub 2003 Oct 10.
2003
Yeh S, Hu YC, Wang PH, Xie C, Xu Q, Tsai MY, Dong Z, Wang RS, Lee TH, Chang C. "Abnormal mammary gland development and growth retardation in female mice and MCF7 breast cancer cells lacking androgen receptor." The Journal of experimental medicine. 2003 198(12):1899-908.
2003
Fu M, Rao M, Wang C, Sakamaki T, Wang J, Di Vizio D, Zhang X, Albanese C, Balk S, Chang C, Fan S, Rosen E, Palvimo JJ, Jänne OA, Muratoglu S, Avantaggiati ML, Pestell RG. "Acetylation of androgen receptor enhances coactivator binding and promotes prostate cancer cell growth." Molecular and cellular biology. 2003 23(23):8563-75.
2003
Collins LL, Lee HJ, Chen YT, Chang M, Hsu HY, Yeh S, Chang C. "The androgen receptor in spermatogenesis." Cytogenetic and genome research. 2003 103(3-4):299-301.
2002 Nov 15
Kang HY, Huang KE, Chang SY, Ma WL, Lin WJ, Chang C. "Differential modulation of androgen receptor-mediated transactivation by Smad3 and tumor suppressor Smad4." The Journal of biological chemistry. 2002 Nov 15; 277(46):43749-56. Epub 2002 Sep 10.
2002 Nov 7
Ohtsu H, Xiao Z, Ishida J, Nagai M, Wang HK, Itokawa H, Su CY, Shih C, Chiang T, Chang E, Lee Y, Tsai MY, Chang C, Lee KH. "Antitumor agents. 217. Curcumin analogues as novel androgen receptor antagonists with potential as anti-prostate cancer agents." Journal of medicinal chemistry. 2002 Nov 7; 45(23):5037-42.
2002 Nov 1
Lee YF, Lin WJ, Huang J, Messing EM, Chan FL, Wilding G, Chang C. "Activation of mitogen-activated protein kinase pathway by the antiandrogen hydroxyflutamide in androgen receptor-negative prostate cancer cells." Cancer research. 2002 Nov 1; 62(21):6039-44.
2002 Oct 15
Yeh S, Tsai MY, Xu Q, Mu XM, Lardy H, Huang KE, Lin H, Yeh SD, Altuwaijri S, Zhou X, Xing L, Boyce BF, Hung MC, Zhang S, Gan L, Chang C, Hung MC. "Generation and characterization of androgen receptor knockout (ARKO) mice: an in vivo model for the study of androgen functions in selective tissues." Proceedings of the National Academy of Sciences of the United States of America. 2002 Oct 15; 99(21):13498-503. Epub 2002 Oct 07.
2002 Oct
Heinlein CA, Chang C. "The roles of androgen receptors and androgen-binding proteins in nongenomic androgen actions." Molecular endocrinology. 2002 Oct; 16(10):2181-7.
2002 Sep 27
Thin TH, Kim E, Yeh S, Sampson ER, Chen YT, Collins LL, Basavappa R, Chang C. "Mutations in the helix 3 region of the androgen receptor abrogate ARA70 promotion of 17beta-estradiol-induced androgen receptor transactivation." The Journal of biological chemistry. 2002 Sep 27; 277(39):36499-508. Epub 2002 Jun 14.
2002 Sep 27
Lin HK, Altuwaijri S, Lin WJ, Kan PY, Collins LL, Chang C. "Proteasome activity is required for androgen receptor transcriptional activity via regulation of androgen receptor nuclear translocation and interaction with coregulators in prostate cancer cells." The Journal of biological chemistry. 2002 Sep 27; 277(39):36570-6. Epub 2002 Jul 15.
2002 Sep 13
Hu YC, Shyr CR, Che W, Mu XM, Kim E, Chang C. "Suppression of estrogen receptor-mediated transcription and cell growth by interaction with TR2 orphan receptor." The Journal of biological chemistry. 2002 Sep 13; 277(37):33571-9. Epub 2002 Jul 01.
2002 Aug 1
Lin HK, Wang L, Hu YC, Altuwaijri S, Chang C. "Phosphorylation-dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase." The EMBO journal. 2002 Aug 1; 21(15):4037-48.
2002 Aug
Lee YF, Lee HJ, Chang C. "Recent advances in the TR2 and TR4 orphan receptors of the nuclear receptor superfamily." The Journal of steroid biochemistry and molecular biology. 2002 Aug; 81(4-5):291-308.
2002 Jul
Shyr CR, Collins LL, Mu XM, Platt KA, Chang C. "Spermatogenesis and testis development are normal in mice lacking testicular orphan nuclear receptor 2." Molecular and cellular biology. 2002 Jul; 22(13):4661-6.
2002 Jun 10
Li MT, Richter F, Chang C, Irwin RJ, Huang H. "Androgen and retinoic acid interaction in LNCaP cells, effects on cell proliferation and expression of retinoic acid receptors and epidermal growth factor receptor." BMC cancer. 2002 Jun 10; 2:16. Epub 2002 Jun 10.
2002 May 3
Wang X, Yang Y, Guo X, Sampson ER, Hsu CL, Tsai MY, Yeh S, Wu G, Guo Y, Chang C. "Suppression of androgen receptor transactivation by Pyk2 via interaction and phosphorylation of the ARA55 coregulator." The Journal of biological chemistry. 2002 May 3; 277(18):15426-31. Epub 2002 Feb 20.
2002 May
Fu M, Wang C, Wang J, Zhang X, Sakamaki T, Yeung YG, Chang C, Hopp T, Fuqua SA, Jaffray E, Hay RT, Palvimo JJ, Jänne OA, Pestell RG. "Androgen receptor acetylation governs trans activation and MEKK1-induced apoptosis without affecting in vitro sumoylation and trans-repression function." Molecular and cellular biology. 2002 May; 22(10):3373-88.
2002 Apr 26
Shyr CR, Hu YC, Kim E, Chang C. "Modulation of estrogen receptor-mediated transactivation by orphan receptor TR4 in MCF-7 cells." The Journal of biological chemistry. 2002 Apr 26; 277(17):14622-8. Epub 2002 Feb 13.
2002 Apr
Hsing AW, Chokkalingam AP, Gao YT, Wu G, Wang X, Deng J, Cheng J, Sesterhenn IA, Mostofi FK, Chiang T, Chen YL, Stanczyk FZ, Chang C. "Polymorphic CAG/CAA repeat length in the AIB1/SRC-3 gene and prostate cancer risk: a population-based case-control study." Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2002 Apr; 11(4):337-41.
2002 Apr
Heinlein CA, Chang C. "Androgen receptor (AR) coregulators: an overview." Endocrine reviews. 2002 Apr; 23(2):175-200.
2002 Feb 15
Miyamoto H, Rahman M, Takatera H, Kang HY, Yeh S, Chang HC, Nishimura K, Fujimoto N, Chang C. "A dominant-negative mutant of androgen receptor coregulator ARA54 inhibits androgen receptor-mediated prostate cancer growth." The Journal of biological chemistry. 2002 Feb 15; 277(7):4609-17. Epub 2001 Oct 22.
2002 Jan 22
Ting HJ, Yeh S, Nishimura K, Chang C. "Supervillin associates with androgen receptor and modulates its transcriptional activity." Proceedings of the National Academy of Sciences of the United States of America. 2002 Jan 22; 99(2):661-6. Epub 2002 Jan 15.
2002 Jan 18
Schinner S, Dellas C, Schroder M, Heinlein CA, Chang C, Fischer J, Knepel W. "Repression of glucagon gene transcription by peroxisome proliferator-activated receptor gamma through inhibition of Pax6 transcriptional activity." The Journal of biological chemistry. 2002 Jan 18; 277(3):1941-8. Epub 2001 Nov 13.
2002
Shih, C.; Chang, E.; Zhang, Y.; Lai, C.; Su, C.; Chen, Y.; Chang, H.; Chiang, T.; and Chang, C. ""The use of a flow cytometry analysis in the study of different expression of androgen receptor in human prostate cancer LNCaP and PC-3 cells."". New Taipei Journal of Medicine. 2002; 4: 151-158.
2002
Lin, HK.; Wang, L.; Hu, YC.; Altuwaijri, S.; and Chang, C. ""Phosphorylation-dependent ubiquitination and degradation of AR by Akt requires Mdm2 E3 ligase."". EMBO 21, 1-12. 2002; 21: 1-12.
2001 Nov 2
Wang X, Yeh S, Wu G, Hsu CL, Wang L, Chiang T, Yang Y, Guo Y, Chang C. "Identification and characterization of a novel androgen receptor coregulator ARA267-alpha in prostate cancer cells." The Journal of biological chemistry. 2001 Nov 2; 276(44):40417-23. Epub 2001 Aug 16.
2001 Oct
Inui S, Nakajima T, Fukuzato Y, Fujimoto N, Chang C, Yoshikawa K, Itami S. "Potential anti-androgenic activity of roxithromycin in skin." Journal of dermatological science. 2001 Oct; 27(2):147-51.
2001 Aug 3
Lee HJ, Lee YF, Chang C. "TR4 orphan receptor represses the human steroid 21-hydroxylase gene expression through the monomeric AGGTCA motif." Biochemical and biophysical research communications. 2001 Aug 3; 285(5):1361-8.
2001 Aug
Si ML, Al-Sharafi B, Lai CC, Khardori R, Chang C, Su CY. "Gender difference in cytoprotection induced by estrogen on female and male bovine aortic endothelial cells." Endocrine. 2001 Aug; 15(3):255-62.
2001 Jul 20
Collins LL, Lin DL, Mu XM, Chang C. "Feedback regulation between orphan nuclear receptor TR2 and human papilloma virus type 16." The Journal of biological chemistry. 2001 Jul 20; 276(29):27316-21. Epub 2001 May 17.
2001 Jun 19
Lin HK, Yeh S, Kang HY, Chang C. "Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor." Proceedings of the National Academy of Sciences of the United States of America. 2001 Jun 19; 98(13):7200-5. Epub 2001 Jun 12.
2001 Mar 30
Lee DK, Duan HO, Chang C. "Androgen receptor interacts with the positive elongation factor P-TEFb and enhances the efficiency of transcriptional elongation." The Journal of biological chemistry. 2001 Mar 30; 276(13):9978-84. Epub 2000 Dec 21.
2001 Mar 13
Kang HY, Lin HK, Hu YC, Yeh S, Huang KE, Chang C. "From transforming growth factor-beta signaling to androgen action: identification of Smad3 as an androgen receptor coregulator in prostate cancer cells." Proceedings of the National Academy of Sciences of the United States of America. 2001 Mar 13; 98(6):3018-23. Epub 2001 Mar 06.
2001 Mar
Mantalaris A, Panoskaltsis N, Sakai Y, Bourne P, Chang C, Messing EM, Wu JH. "Localization of androgen receptor expression in human bone marrow." The Journal of pathology. 2001 Mar; 193(3):361-6.
2001 Mar
Heinlein CA, Chang C. "Role of chaperones in nuclear translocation and transactivation of steroid receptors." Endocrine. 2001 Mar; 14(2):143-9.
2001
Sampson ER, Yeh SY, Chang HC, Tsai MY, Wang X, Ting HJ, Chang C. "Identification and characterization of androgen receptor associated coregulators in prostate cancer cells." Journal of biological regulators and homeostatic agents. 2001 15(2):123-9.
2001
Kuo SM, Huang CT, Blum P, Chang C. "Quercetin cumulatively enhances copper induction of metallothionein in intestinal cells." Biological trace element research. 2001 84(1-3):1-10.
2000 Oct 10
Yeh S, Hu YC, Rahman M, Lin HK, Hsu CL, Ting HJ, Kang HY, Chang C. "Increase of androgen-induced cell death and androgen receptor transactivation by BRCA1 in prostate cancer cells." Proceedings of the National Academy of Sciences of the United States of America. 2000 Oct 10; 97(21):11256-61.
2000 Sep 15
Hsing AW, Gao YT, Wu G, Wang X, Deng J, Chen YL, Sesterhenn IA, Mostofi FK, Benichou J, Chang C. "Polymorphic CAG and GGN repeat lengths in the androgen receptor gene and prostate cancer risk: a population-based case-control study in China." Cancer research. 2000 Sep 15; 60(18):5111-6.
2000 Aug 4
Mu X, Liu Y, Collins LL, Kim E, Chang C. "The p53/retinoblastoma-mediated repression of testicular orphan receptor-2 in the rhesus monkey with cryptorchidism." The Journal of biological chemistry. 2000 Aug 4; 275(31):23877-83.
2000 Jul 1
Kinoshita H, Shi Y, Sandefur C, Meisner LF, Chang C, Choon A, Reznikoff CR, Bova GS, Friedl A, Jarrard DF. "Methylation of the androgen receptor minimal promoter silences transcription in human prostate cancer." Cancer research. 2000 Jul 1; 60(13):3623-30.
2000 Jun
Inui S, Itami S, Pan HJ, Chang C. "Lack of androgen receptor transcriptional activity in human keratinocytes." Journal of dermatological science. 2000 Jun; 23(2):87-92.
2000 Apr 14
van Schaick HS, Rosmalen JG, Lopes da Silva S, Chang C, Burbach JP. "Expression of the orphan receptor TR4 during brain development of the rat." Brain research. Molecular brain research. 2000 Apr 14; 77(1):104-10.
2000 Mar 31
Lee DK, Duan HO, Chang C. "From androgen receptor to the general transcription factor TFIIH. Identification of cdk activating kinase (CAK) as an androgen receptor NH(2)-terminal associated coactivator." The Journal of biological chemistry. 2000 Mar 31; 275(13):9308-13.
2000 Mar
Hsiao PW, Thin TH, Lin DL, Chang C. "Differential regulation of testosterone vs. 5alpha-dihydrotestosterone by selective androgen response elements." Molecular and cellular biochemistry. 2000 Mar; 206(1-2):169-75.
2000 Feb
Wang C, Young WJ, Chang C. "Isolation and characterization of the androgen receptor mutants with divergent transcriptional activity in response to hydroxyflutamide." Endocrine. 2000 Feb; 12(1):69-76.
2000 Feb
Lin DL, Chang C. "Identification of an essential cis-acting element (TR2-PACE) in the 5' promoter of human TR2 orphan receptor gene." Endocrine. 2000 Feb; 12(1):89-97.
2000 Jan
Miyamoto H, Chang C. "Antiandrogens fail to block androstenedione-mediated mutated androgen receptor transactivation in human prostate cancer cells." International journal of urology : official journal of the Japanese Urological Association. 2000 Jan; 7(1):32-4.
2000
Yeh S, Sampson ER, Lee DK, Kim E, Hsu CL, Chen YL, Chang HC, Altuwaijri S, Huang KE, Chang C. "Functional analysis of androgen receptor N-terminal and ligand binding domain interacting coregulators in prostate cancer." Journal of the Formosan Medical Association = Taiwan yi zhi. 2000 99(12):885-94.
1999 Nov 15
Kameoka S, Leavitt P, Chang C, Kuo SM. "Expression of antioxidant proteins in human intestinal Caco-2 cells treated with dietary flavonoids." Cancer letters. 1999 Nov 15; 146(2):161-7.
1999 Nov
Shih CC, Young WJ, Wang CH, Jin LP, Ji XD, Guan Q, Wang M, Chang C. "Monoclonal anti-androgen receptor antibodies: production, characterization and potential diagnostic applications." Molecular and cellular biochemistry. 1999 Nov; 201(1-2):131-40.
1999 Oct
Yeh S, Kang HY, Miyamoto H, Nishimura K, Chang HC, Ting HJ, Rahman M, Lin HK, Fujimoto N, Hu YC, Mizokami A, Huang KE, Chang C. "Differential induction of androgen receptor transactivation by different androgen receptor coactivators in human prostate cancer DU145 cells." Endocrine. 1999 Oct; 11(2):195-202.
1999 Sep 28
Chang HC, Miyamoto H, Marwah P, Lardy H, Yeh S, Huang KE, Chang C. "Suppression of Delta(5)-androstenediol-induced androgen receptor transactivation by selective steroids in human prostate cancer cells." Proceedings of the National Academy of Sciences of the United States of America. 1999 Sep 28; 96(20):11173-7.
1999 Aug 6
Hsiao PW, Chang C. "Isolation and characterization of ARA160 as the first androgen receptor N-terminal-associated coactivator in human prostate cells." The Journal of biological chemistry. 1999 Aug 6; 274(32):22373-9.
1999 Jul 16
Hsiao PW, Lin DL, Nakao R, Chang C. "The linkage of Kennedy's neuron disease to ARA24, the first identified androgen receptor polyglutamine region-associated coactivator." The Journal of biological chemistry. 1999 Jul 16; 274(29):20229-34.
1999 Jun 4
Heinlein CA, Ting HJ, Yeh S, Chang C. "Identification of ARA70 as a ligand-enhanced coactivator for the peroxisome proliferator-activated receptor gamma." The Journal of biological chemistry. 1999 Jun 4; 274(23):16147-52.
1999 Jun 4
Lee YF, Young WJ, Lin WJ, Shyr CR, Chang C. "Differential regulation of direct repeat 3 vitamin D3 and direct repeat 4 thyroid hormone signaling pathways by the human TR4 orphan receptor." The Journal of biological chemistry. 1999 Jun 4; 274(23):16198-205.
1999 Jun
Yeh S, Chang HC, Miyamoto H, Takatera H, Rahman M, Kang HY, Thin TH, Lin HK, Chang C. "Differential induction of the androgen receptor transcriptional activity by selective androgen receptor coactivators." The Keio journal of medicine. 1999 Jun; 48(2):87-92.
1999 May 15
Yang CR, Yeh S, Leskov K, Odegaard E, Hsu HL, Chang C, Kinsella TJ, Chen DJ, Boothman DA. "Isolation of Ku70-binding proteins (KUBs)." Nucleic acids research. 1999 May 15; 27(10):2165-74.
1999 May 11
Yeh S, Lin HK, Kang HY, Thin TH, Lin MF, Chang C. "From HER2/Neu signal cascade to androgen receptor and its coactivators: a novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells." Proceedings of the National Academy of Sciences of the United States of America. 1999 May 11; 96(10):5458-63.
1999 May
Wang C, Young WJ, Chang C. "Androgen effects on the solubility and conformational change of the androgen receptor in baculovirus expression system." Molecular and cellular biochemistry. 1999 May; 195(1-2):19-23.
1999 Apr
Inui S, Lee YF, Haake AR, Goldsmith LA, Chang C. "Induction of TR4 orphan receptor by retinoic acid in human HaCaT keratinocytes." The Journal of investigative dermatology. 1999 Apr; 112(4):426-31.
1999 Apr
Lee HJ, Lee YF, Chang C. "Identification of the histamine H1 receptor gene as a differentially repressed target of the human TR2 orphan receptor." Molecular and cellular biochemistry. 1999 Apr; 194(1-2):199-207.
1999 Mar 26
Kang HY, Yeh S, Fujimoto N, Chang C. "Cloning and characterization of human prostate coactivator ARA54, a novel protein that associates with the androgen receptor." The Journal of biological chemistry. 1999 Mar 26; 274(13):8570-6.
1999 Mar 19
Fujimoto N, Yeh S, Kang HY, Inui S, Chang HC, Mizokami A, Chang C. "Cloning and characterization of androgen receptor coactivator, ARA55, in human prostate." The Journal of biological chemistry. 1999 Mar 19; 274(12):8316-21.
1999
Lee YF, Shyr CR, Thin TH, Lin WJ, Chang C. "Convergence of two repressors through heterodimer formation of androgen receptor and testicular orphan receptor-4: a unique signaling pathway in the steroid receptor superfamily." Proceedings of the National Academy of Sciences of the United States of America. 1999 96(26):14724-9.
1999
Pan HJ, Uno H, Inui S, Fulmer NO, Chang C. "Roles of testosterone in the growth of keratinocytes through bald frontal dermal papilla cells." Endocrine. 1999 11(3):321-7.
1998 Sep 15
Miyamoto H, Yeh S, Lardy H, Messing E, Chang C. "Delta5-androstenediol is a natural hormone with androgenic activity in human prostate cancer cells." Proceedings of the National Academy of Sciences of the United States of America. 1998 Sep 15; 95(19):11083-8.
1998 Aug 14
Young WJ, Lee YF, Smith SM, Chang C. "A bidirectional regulation between the TR2/TR4 orphan receptors (TR2/TR4) and the ciliary neurotrophic factor (CNTF) signaling pathway." The Journal of biological chemistry. 1998 Aug 14; 273(33):20877-85.
1998 Aug
Chen X, Zachar V, Chang C, Ebbesen P, Liu X. "Differential expression of Nur77 family members in human T-lymphotropic virus type 1-infected cells: transactivation of the TR3/nur77 gene by Tax protein." Journal of virology. 1998 Aug; 72(8):6902-6.
1998 Aug
Mu XM, Young WJ, Liu YX, Uemura H, Chang C. "Induction of an intronic enhancer of the human ciliary neurotrophic factor receptor (CNTFRalpha) gene by the TR3 orphan receptor." Endocrine. 1998 Aug; 9(1):27-32.
1998 Aug
Pan HJ, Wilding G, Uno H, Inui S, Goldsmith L, Messing E, Chang C. "Evaluation of RU58841 as an anti-androgen in prostate PC3 cells and a topical anti-alopecia agent in the bald scalp of stumptailed macaques." Endocrine. 1998 Aug; 9(1):39-43.
1998 Aug
Young WJ, Chang C. "Ontogeny and autoregulation of androgen receptor mRNA expression in the nervous system." Endocrine. 1998 Aug; 9(1):79-88.
1998 Jul 20
Yeh S, Miyamoto H, Nishimura K, Kang H, Ludlow J, Hsiao P, Wang C, Su C, Chang C. "Retinoblastoma, a tumor suppressor, is a coactivator for the androgen receptor in human prostate cancer DU145 cells." Biochemical and biophysical research communications. 1998 Jul 20; 248(2):361-7.
1998 Jun 23
Miyamoto H, Yeh S, Wilding G, Chang C. "Promotion of agonist activity of antiandrogens by the androgen receptor coactivator, ARA70, in human prostate cancer DU145 cells." Proceedings of the National Academy of Sciences of the United States of America. 1998 Jun 23; 95(13):7379-84.
1998 Jun
Cardillo MR, Petrangeli E, Aliotta N, Salvatori L, Ravenna L, Chang C, Castagna G. "Androgen receptors in ovarian tumors: correlation with oestrogen and progesterone receptors in an immunohistochemical and semiquantitative image analysis study." Journal of experimental & clinical cancer research : CR. 1998 Jun; 17(2):231-7.
1998 May 29
Lee YF, Young WJ, Burbach JP, Chang C. "Negative feedback control of the retinoid-retinoic acid/retinoid X receptor pathway by the human TR4 orphan receptor, a member of the steroid receptor superfamily." The Journal of biological chemistry. 1998 May 29; 273(22):13437-43.
1998 May 12
Yeh S, Miyamoto H, Shima H, Chang C. "From estrogen to androgen receptor: a new pathway for sex hormones in prostate." Proceedings of the National Academy of Sciences of the United States of America. 1998 May 12; 95(10):5527-32.
1998 May
Uemura H, Chang C. "Antisense TR3 orphan receptor can increase prostate cancer cell viability with etoposide treatment." Endocrinology. 1998 May; 139(5):2329-34.
1998 Apr
Lin DL, Wu SQ, Chang C. "The genomic structure and chromosomal location of the human TR2 orphan receptor, a member of the steroid receptor superfamily." Endocrine. 1998 Apr; 8(2):123-34.
1998 Apr
Hwang SB, Burbach JP, Chang C. "TR4 orphan receptor crosstalks to chicken ovalbumin upstream protein-transcription factor and thyroid hormone receptor to induce the transcriptional activity of the human immunodeficiency virus type 1 long-terminal repeat." Endocrine. 1998 Apr; 8(2):169-75.
1998 Mar 6
Lin MF, Meng TC, Rao PS, Chang C, Schonthal AH, Lin FF. "Expression of human prostatic acid phosphatase correlates with androgen-stimulated cell proliferation in prostate cancer cell lines." The Journal of biological chemistry. 1998 Mar 6; 273(10):5939-47.
1998 Mar
Su CY, Chong KY, Owen OE, Dillmann WH, Chang C, Lai CC. "Constitutive and inducible hsp70s are involved in oxidative resistance evoked by heat shock or ethanol." Journal of molecular and cellular cardiology. 1998 Mar; 30(3):587-98.
1998 Mar
Chong KY, Lai CC, Lille S, Chang C, Su CY. "Stable overexpression of the constitutive form of heat shock protein 70 confers oxidative protection." Journal of molecular and cellular cardiology. 1998 Mar; 30(3):599-608.
1998
Jarrard DF, Kinoshita H, Shi Y, Sandefur C, Hoff D, Meisner LF, Chang C, Herman JG, Isaacs WB, Nassif N. "Methylation of the androgen receptor promoter CpG island is associated with loss of androgen receptor expression in prostate cancer cells." Cancer research. 1998 58(23):5310-4.
1998
Cardillo, MR.; Petrangeli, E.; Ravenna, L.; Salvatori, L.; Chang, C.; DiSilverio, F. "Immunohistochemical quantification and determination of Cathepsin D in prostatic neoplasia: correlation with steroid." Applied Immunohistochemistry 6(3), 133-139. 1998; 6(3): 133-139.
1998
Mu, XM.; Liu, YX.; and Chang, C. "Mechanism of the interaction between orphan receptor TR3 and cis-acting element in CNTFR? gene." Chinese J. Biochemistry and Molecular Biology . 1998; 14: 484-492.
1998
Chang C, Pan HJ. "Thyroid hormone direct repeat 4 response element is a positive regulatory element for the human TR2 orphan receptor, a member of steroid receptor superfamily." Molecular and cellular biochemistry. 1998 189(1-2):195-200.
1997 Aug
Magi-Galluzzi C, Xu X, Hlatky L, Hahnfeldt P, Kaplan I, Hsiao P, Chang C, Loda M. "Heterogeneity of androgen receptor content in advanced prostate cancer." Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 1997 Aug; 10(8):839-45.
1997 Jun 9
Chang C, Lee HJ, Lee YF. "Identification of the human aldolase A gene as the first induced target for the TR2 orphan receptor, a member of the steroid hormone receptor superfamily." Biochemical and biophysical research communications. 1997 Jun 9; 235(1):205-11.
1997 Jun
Wiren KM, Zhang X, Chang C, Keenan E, Orwoll ES. "Transcriptional up-regulation of the human androgen receptor by androgen in bone cells." Endocrinology. 1997 Jun; 138(6):2291-300.
1997 May 13
Lin TM, Chang C. "Cloning and characterization of TDD5, an androgen target gene that is differentially repressed by testosterone and dihydrotestosterone." Proceedings of the National Academy of Sciences of the United States of America. 1997 May 13; 94(10):4988-93.
1997 May 2
Lee YF, Pan HJ, Burbach JP, Morkin E, Chang C. "Identification of direct repeat 4 as a positive regulatory element for the human TR4 orphan receptor. A modulator for the thyroid hormone target genes." The Journal of biological chemistry. 1997 May 2; 272(18):12215-20.
1997 Mar 22
Yeh S, Miyamoto H, Chang C. "Hydroxyflutamide may not always be a pure antiandrogen." Lancet. 1997 Mar 22; 349(9055):852-3.
1997 Feb
Schirar A, Chang C, Rousseau JP. "Localization of androgen receptor in nitric oxide synthase- and vasoactive intestinal peptide-containing neurons of the major pelvic ganglion innervating the rat penis." Journal of neuroendocrinology. 1997 Feb; 9(2):141-50.
1997 Jan 31
Young WJ, Smith SM, Chang C. "Induction of the intronic enhancer of the human ciliary neurotrophic factor receptor (CNTFRalpha) gene by the TR4 orphan receptor. A member of steroid receptor superfamily." The Journal of biological chemistry. 1997 Jan 31; 272(5):3109-16.
1997 Jan
Obana N, Chang C, Uno H. "Inhibition of hair growth by testosterone in the presence of dermal papilla cells from the frontal bald scalp of the postpubertal stumptailed macaque." Endocrinology. 1997 Jan; 138(1):356-61.
1997
Miyamoto, H.; Yeh, S.; Kinoshita, H.; Fujimoto, N.; Nishimura, K.; Inui, S.; Mizokami, A.; Uemura, H.; and Chang, C. "Androgen receptor and androgen receptor cofactors in prostate." Proc. Jap. Nat. Conf. Andrology, 1-4. 1997; : 1-4.
1996 Oct 18
Keller ET, Chang C, Ershler WB. "Inhibition of NFkappaB activity through maintenance of IkappaBalpha levels contributes to dihydrotestosterone-mediated repression of the interleukin-6 promoter." The Journal of biological chemistry. 1996 Oct 18; 271(42):26267-75.
1996 Jul 1
Lee HJ, Mowszowicz I, Chang C. "The first detection of complete androgen insensitivity with no mutation in the coding sequence of the androgen receptor gene." Frontiers in bioscience : a journal and virtual library. 1996 Jul 1; 1:a34-8. Epub 1996 Jul 01.
1996 Jun 21
Lin DL, Chang C. "p53 is a mediator for radiation-repressed human TR2 orphan receptor expression in MCF-7 cells, a new pathway from tumor suppressor to member of the steroid receptor superfamily." The Journal of biological chemistry. 1996 Jun 21; 271(25):14649-52.
1996 May 28
Yeh S, Chang C. "Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells." Proceedings of the National Academy of Sciences of the United States of America. 1996 May 28; 93(11):5517-21.
1996 Apr 26
Lee HJ, Young WJ, Shih CY, Chang C. "Suppression of the human erythropoietin gene expression by the TR2 orphan receptor, a member of the steroid receptor superfamily." The Journal of biological chemistry. 1996 Apr 26; 271(17):10405-12.
1995 May
Lopes da Silva S, Van Horssen AM, Chang C, Burbach JP. "Expression of nuclear hormone receptors in the rat supraoptic nucleus." Endocrinology. 1995 May; 136(5):2276-83.
1995 Apr 28
Garcia-Arenas R, Lin FF, Lin D, Jin LP, Shih CC, Chang C, Lin MF. "The expression of prostatic acid phosphatase is transcriptionally regulated in human prostate carcinoma cells." Molecular and cellular endocrinology. 1995 Apr 28; 111(1):29-37.
1995 Apr
Ideta R, Yeh S, Lee Y, Adachi K, Takeda H, Su C, Saltzman A, Chang C. "Gene expression of the androgen repressed rat TR2 orphan receptor: a member of steroid receptor superfamily." Endocrine. 1995 Apr; 3(4):277-83.
1995 Mar 10
Uemura H, Mizokami A, Chang C. "Identification of a new enhancer in the promoter region of human TR3 orphan receptor gene. A member of steroid receptor superfamily." The Journal of biological chemistry. 1995 Mar 10; 270(10):5427-33.
1995 Mar 10
Lee HJ, Chang C. "Identification of human TR2 orphan receptor response element in the transcriptional initiation site of the simian virus 40 major late promoter." The Journal of biological chemistry. 1995 Mar 10; 270(10):5434-40.
1995
Lin TM, Young WJ, Chang C. "Multiple functions of the TR2-11 orphan receptor in modulating activation of two key cis-acting elements involved in the retinoic acid signal transduction system." The Journal of biological chemistry. 1995 270(50):30121-8.
1995
Lee HJ, Lee Y, Burbach JP, Chang C. "Suppression of gene expression on the simian virus 40 major late promoter by human TR4 orphan receptor. A member of the steroid receptor superfamily." The Journal of biological chemistry. 1995 270(50):30129-33.
1995
Yuan, Z.; Zhang, Y.; Chang, C.; and Zhang, YL. "Differential regulation of glutathione S-transferase -Yb1 mRNA levels in rat prostate, liver, and brain by androgen." Cell Research. 1995; 55: 235-242. Link
1995
Chang C, Saltzman A, Yeh S, Young W, Keller E, Lee HJ, Wang C, Mizokami A. "Androgen receptor: an overview." Critical reviews in eukaryotic gene expression. 1995 5(2):97-125.
1994 Nov 15
Pugh TD, Chang C, Uemura H, Weindruch R. "Prostatic localization of spontaneous early invasive carcinoma in Lobund-Wistar rats." Cancer research. 1994 Nov 15; 54(22):5766-70.
1994 Oct 14
Mizokami A, Chang C. "Induction of translation by the 5'-untranslated region of human androgen receptor mRNA." The Journal of biological chemistry. 1994 Oct 14; 269(41):25655-9.
1994 Jun 21
Chang C, Da Silva SL, Ideta R, Lee Y, Yeh S, Burbach JP. "Human and rat TR4 orphan receptors specify a subclass of the steroid receptor superfamily." Proceedings of the National Academy of Sciences of the United States of America. 1994 Jun 21; 91(13):6040-4.
1994 Apr
Mizuno Y, Hosoi T, Inoue S, Ikegami A, Kaneki M, Akedo Y, Nakamura T, Ouchi Y, Chang C, Orimo H. "Immunocytochemical identification of androgen receptor in mouse osteoclast-like multinucleated cells." Calcified tissue international. 1994 Apr; 54(4):325-6.
1994 Jan
Mizokami A, Yeh SY, Chang C. "Identification of 3',5'-cyclic adenosine monophosphate response element and other cis-acting elements in the human androgen receptor gene promoter." Molecular endocrinology. 1994 Jan; 8(1):77-88.
1994
Young, W-J.; Roecker, EB.; Weindruch, R.; and Chang, C. "Quantitation of androgen receptor mRNA by competitive reverse transcription-polymerase chain reaction." Endocrine. 1994; 2: 321-329. Link
1994
Joubert , Y,; Tobin, C,; Lebart, MC,; and Chang, C. "Ultrastructural localization of androgen receptors in levator ani muscle in the rat." Proc. Intl. Conf. Elec. Microscopy. 1994; 13: 325-326.
1994
Lustig RH, Hua P, Smith LS, Wang C, Chang C. "An in vitro model for the effects of androgen on neurons employing androgen receptor-transfected PC12 cells." Molecular and cellular neurosciences. 1994 5(6):587-96.
1993 Sep 15
Zhang YL, Wang C, Wilding G, Chang C. "Identification of an androgen-induced C3-P4 DNA binding protein in the cytosol of rat ventral prostate." Biochemical and biophysical research communications. 1993 Sep 15; 195(2):710-6.
1993 Jul 15
Lee HJ, Kokontis J, Wang KC, Chang C. "The use of a DNA-binding domain replacement method for the detection of a potential TR3 orphan receptor response element in the mouse mammary tumor virus long terminal repeat." Biochemical and biophysical research communications. 1993 Jul 15; 194(1):97-103.
1993 Jul
Yoshimura Y, Chang C, Okamoto T, Tamura T. "Immunolocalization of androgen receptor in the small, preovulatory, and postovulatory follicles of laying hens." General and comparative endocrinology. 1993 Jul; 91(1):81-9.
1993 Jul
Mowszowicz I, Lee HJ, Chen HT, Mestayer C, Portois MC, Cabrol S, Mauvais-Jarvis P, Chang C. "A point mutation in the second zinc finger of the DNA-binding domain of the androgen receptor gene causes complete androgen insensitivity in two siblings with receptor-positive androgen resistance." Molecular endocrinology. 1993 Jul; 7(7):861-9.
1993 Jan
Rennie PS, Bruchovsky N, Leco KJ, Sheppard PC, McQueen SA, Cheng H, Snoek R, Hamel A, Bock ME, MacDonald BS. "Characterization of two cis-acting DNA elements involved in the androgen regulation of the probasin gene." Molecular endocrinology. 1993 Jan; 7(1):23-36.
1993
Mowszowicz, I.; Lee, H-J.; Portois, M-C.; Kuttenn, F.; and Chang, C. "Complete androgen insensitivity due to a single base substitution in exon 8 of the steroid-binding domain of the androgen receptor." Endocrine. 1993; 1: 203-209. Link
1993
Chang, C.; Saltzman, AG.; Lee, H.; Uemura, H.; Su, C.; Chodak, GW.; Nakamoto, T.; LeBeau, M.; Espinosa, R.; Davis, E.; Lemons, R.; Sivak, L.; and Shih, C. "Genomic structure, chromosomal localization and expression of an inducible TR3 orphan receptor: A member of the steroid receptor superfamily." Endocrine. 1993; 1: 541-549.
1993
Kaku, A,.; Chang, C.; Tamura, T.; Okamoto, T.; and Yoshimura, Y. "Immunolocalization of androgen receptor in the cloacal gland of male Japanese quail (Coturnis coturnix japonica)." Japanese Poultry Science. 1993; : 413-418.
1992 Jul 1
Chang C, Wang C, DeLuca HF, Ross TK, Shih CC. "Characterization of human androgen receptor overexpressed in the baculovirus system." Proceedings of the National Academy of Sciences of the United States of America. 1992 Jul 1; 89(13):5946-50.
1992 Jul
Prior L, Bordet S, Trifiro MA, Mhatre A, Kaufman M, Pinsky L, Wrogeman K, Belsham DD, Pereira F, Greenberg C. "Replacement of arginine 773 by cysteine or histidine in the human androgen receptor causes complete androgen insensitivity with different receptor phenotypes." American journal of human genetics. 1992 Jul; 51(1):143-55.
1992 May 29
Gipp JJ, Chang C, Mulcahy RT. "Cloning and nucleotide sequence of a full-length cDNA for human liver gamma-glutamylcysteine synthetase." Biochemical and biophysical research communications. 1992 May 29; 185(1):29-35.
1992 Mar
Chodak GW, Kranc DM, Puy LA, Takeda H, Johnson K, Chang C. "Nuclear localization of androgen receptor in heterogeneous samples of normal, hyperplastic and neoplastic human prostate." The Journal of urology. 1992 Mar; 147(3 Pt 2):798-803.
1992 Feb 1
Nakamoto T, Chang CS, Li AK, Chodak GW. "Basic fibroblast growth factor in human prostate cancer cells." Cancer research. 1992 Feb 1; 52(3):571-7.
1992
Jiang SY, Wolf DM, Yingling JM, Chang C, Jordan VC. "An estrogen receptor positive MCF-7 clone that is resistant to antiestrogens and estradiol." Molecular and cellular endocrinology. 1992 90(1):77-86.
1992
Leav I, Kwan PW, Merk FB, Chang C, Ho SM. "Immunohistochemical and in situ hybridization studies of androgen receptor expression in a transplantable androgen-independent prostatic carcinoma line (AIT) of Noble rats." Laboratory investigation; a journal of technical methods and pathology. 1992 67(6):788-95.
1991 Oct
Sanborn BM, Caston LA, Chang C, Liao S, Speller R, Porter LD, Ku CY. "Regulation of androgen receptor mRNA in rat Sertoli and peritubular cells." Biology of reproduction. 1991 Oct; 45(4):634-41.
1991 May 31
Takeda H, Nakamoto T, Kokontis J, Chodak GW, Chang C. "Autoregulation of androgen receptor expression in rodent prostate: immunohistochemical and in situ hybridization analysis." Biochemical and biophysical research communications. 1991 May 31; 177(1):488-96.
1991 Apr
Takeda H, Chang C. "Immunohistochemical and in-situ hybridization analysis of androgen receptor expression during the development of the mouse prostate gland." The Journal of endocrinology. 1991 Apr; 129(1):83-9.
1991 Jan
Trifiro M, Gottlieb B, Pinsky L, Kaufman M, Prior L, Belsham DD, Wrogemann K, Brown CJ, Willard HF, Trapman J. "The 56/58 kDa androgen-binding protein in male genital skin fibroblasts with a deleted androgen receptor gene." Molecular and cellular endocrinology. 1991 Jan; 75(1):37-47.
1991
Mestayer C, Gabou L, Portois MC, Boucekkine C, Chang C, Mowszowicz I. "[Expression of androgen receptor gene in normal subjects and patients with complete androgen insensitivity]." Annales d'endocrinologie. 1991 52(6):431-4.
1991
Kokontis J, Liao S, Chang C. "Transcriptional activation by TR3 receptor, a member of the steroid receptor superfamily." Receptor. 1991 1(4):261-70.
1990 Sep
West NB, Chang CS, Liao SS, Brenner RM. "Localization and regulation of estrogen, progestin and androgen receptors in the seminal vesicle of the rhesus monkey." The Journal of steroid biochemistry and molecular biology. 1990 Sep; 37(1):11-21.
1990 Jul
Takeda H, Chodak G, Mutchnik S, Nakamoto T, Chang C. "Immunohistochemical localization of androgen receptors with mono- and polyclonal antibodies to androgen receptor." The Journal of endocrinology. 1990 Jul; 126(1):17-25.
1990 Jun
Sai TJ, Seino S, Chang CS, Trifiro M, Pinsky L, Mhatre A, Kaufman M, Lambert B, Trapman J, Brinkmann AO. "An exonic point mutation of the androgen receptor gene in a family with complete androgen insensitivity." American journal of human genetics. 1990 Jun; 46(6):1095-100.
1990 May
Imperato-McGinley J, Ip NY, Gautier T, Neuweiler J, Gruenspan H, Liao S, Chang C, Balazs I. "DNA linkage analysis and studies of the androgen receptor gene in a large kindred with complete androgen insensitivity." American journal of medical genetics. 1990 May; 36(1):104-8.
1990 Apr 1
Simerly RB, Chang C, Muramatsu M, Swanson LW. "Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: an in situ hybridization study." The Journal of comparative neurology. 1990 Apr 1; 294(1):76-95.
1990
Kranc DM; Chodak GW; and Chang C. "Androgen receptor staining in heterogeneous samples of normal, hyperplastic, and neoplastic human prostate". Surgical Forum. 1990; 41: 687-689. Link
1990
Masai M, Sumiya H, Akimoto S, Yatani R, Chang CS, Liao SS, Shimazaki J. "Immunohistochemical study of androgen receptor in benign hyperplastic and cancerous human prostates." The Prostate. 1990 17(4):293-300.
1990
Chang C, Kokontis J, Swift S, Liao ST. "Molecular cloning and structural analysis of complementary DNA of human and rat androgen receptors." Progress in clinical and biological research. 1990 322:53-63.
1989 Aug
Buttyan R, Olsson CA, Pintar J, Chang C, Bandyk M, Ng PY, Sawczuk IS. "Induction of the TRPM-2 gene in cells undergoing programmed death." Molecular and cellular biology. 1989 Aug; 9(8):3473-81.
1989 Aug
Chang CS, Whelan CT, Popovich TC, Kokontis J, Liao ST. "Fusion proteins containing androgen receptor sequences and their use in the production of poly- and monoclonal anti-androgen receptor antibodies." Endocrinology. 1989 Aug; 125(2):1097-9.
1989
Chang C, Kokontis J, Acakpo-Satchivi L, Liao S, Takeda H, Chang Y. "Molecular cloning of new human TR2 receptors: a class of steroid receptor with multiple ligand-binding domains." Biochemical and biophysical research communications. 1989 165(2):735-41.
1989
Chang C, Chodak G, Sarac E, Takeda H, Liao S. "Prostate androgen receptor: immunohistological localization and mRNA characterization." Journal of steroid biochemistry. 1989 34(1-6):311-3.
1989
Chang C, Kokontis J, Liao SS, Chang Y. "Isolation and characterization of human TR3 receptor: a member of steroid receptor superfamily." Journal of steroid biochemistry. 1989 34(1-6):391-5.
1988 Oct
Chang CS, Kokontis J, Liao ST. "Structural analysis of complementary DNA and amino acid sequences of human and rat androgen receptors." Proceedings of the National Academy of Sciences of the United States of America. 1988 Oct; 85(19):7211-5.
1988 Sep 15
Chang C, Kokontis J. "Identification of a new member of the steroid receptor super-family by cloning and sequence analysis." Biochemical and biophysical research communications. 1988 Sep 15; 155(2):971-7.
1988 Jun 14
Anderegg RJ, Carr SA, Huang IY, Hiipakka RA, Chang CS, Liao ST. "Correction of the cDNA-derived protein sequence of prostatic spermine binding protein: pivotal role of tandem mass spectrometry in sequence analysis." Biochemistry. 1988 Jun 14; 27(12):4214-21.
1988 Apr 15
Chang CS, Kokontis J, Liao ST. "Molecular cloning of human and rat complementary DNA encoding androgen receptors." Science. 1988 Apr 15; 240(4850):324-6.
1988
Chang, C.; and Liao, S. "Gene expression and structure analysis of cDNA's for androgen-sensitive proteins and different forms of steroid-receptors." Progress in Cancer Research and Therapy. 1988; 35: 43-48.
1987 Nov 25
Chang CS, Kokontis J, Chang CT, Liao SS. "Cloning and sequence analysis of the rat ventral prostate glucocorticoid receptor cDNA." Nucleic acids research. 1987 Nov 25; 15(22):9603.
1987 Sep 5
Chang CS, Saltzman AG, Sorensen NS, Hiipakka RA, Liao SS. "Identification of glutathione S-transferase Yb1 mRNA as the androgen-repressed mRNA by cDNA cloning and sequence analysis." The Journal of biological chemistry. 1987 Sep 5; 262(25):11901-3.
1987 Feb 25
Chang CS, Saltzman AG, Hiipakka RA, Huang IY, Liao SS. "Prostatic spermine-binding protein. Cloning and nucleotide sequence of cDNA, amino acid sequence, and androgenic control of mRNA level." The Journal of biological chemistry. 1987 Feb 25; 262(6):2826-31.
1987 Jan 5
Saltzman AG, Hiipakka RA, Chang C, Liao S. "Androgen repression of the production of a 29-kilodalton protein and its mRNA in the rat ventral prostate." The Journal of biological chemistry. 1987 Jan 5; 262(1):432-7.
1987
Chang CS, Liao SS. "Topographic recognition of cyclic hydrocarbons and related compounds by receptors for androgens, estrogens, and glucocorticoids." Journal of steroid biochemistry. 1987 27(1-3):123-31.
1984 Jan
Liao S, Witte D, Schilling K, Chang C. "The use of a hydroxylapatite-filter steroid receptor assay method in the study of the modulation of androgen receptor interaction." Journal of steroid biochemistry. 1984 Jan; 20(1):11-7.

Books

2005
Chang, et al. Prostate Cancer: Basic Mechanisms and Therapeutic Approaches. : World Scientific, 2005.
2005
Wu C, Yeh S, Xu Q, Yang Z, Chang P, Yu Y, and Chang C. ""Study of androgen receptor roles in prostate cancer using mice lacking functional prostate androgen receptor"". Prostate Cancer: Basic Mechanisms and Therapeutic Approaches.. (Chang C ed).. : World Scientific. USA., 2005. 223-238
2005
Miyamoto, H.; and Chang, C. ""Hormonal therapy for prostate cancer: clinical and experimental evidence."". Prostate Cancer: Basic Mechanisms and Therapeutic Approaches.. (Chang C ed).. : World Scientific. USA., 2005. 1-32
2003
Lee HJ, Sampson ER, Hsu CL, Chen YT and Chang C. ""Androgen receptor."". Molecular mechanisms of action of steroid receptors. (Marija and Costas Demonacos ed).. : Research Signpost, India., 2003. 87-101
2002
Heinlein C and Chang C. ""Signal Transduction Pathways Modulate Androgen Receptor Transcriptional Activity."". Androgens and Androgen Receptor: Mechanisms, Functions and Clinical Application.. (Chang C ed).. : Kluwer, USA., 2002. pp 57-90
2002
Hsing A, Culig Z, Wang X, Uemura H and Chang C. ""The Expanded Poly-Q Length Within AR and AR Coregulator A1B1 And Their Clinical Implications."". Androgens and Androgen Receptor: Mechanisms, Functions and Clinical Application.. (Chang C ed).. : Kluwer, USA., 2002. pp 245-264
2002
Collins L and Chang C. ""Androgens in Spermatogenesis and Contraception."". Androgens and Androgen Receptor: Mechanisms, Functions and Clinical Application.. (Chang C ed).. : Kluwer, USA., 2002. pp 299-324
2002
Sampson E, Yeh S. Miyamoto H, Lee DK, Tsi, MY, Wang X, Hsu CL, and Chang C. ""Interaction of cell cycle regulatory proteins with the androgen receptor."". Steroid hormones and cell cycle regulation.. (Burnstein KL ed).. : Kluwer, USA., 2002. 223-238
2002
Chang, et al. Androgens and Androgen Receptor: Mechanisms, Functions, and Clinical Application. : Kluwer Academic Publishers, 2002.
2002
Heinlein C, Sampson E and Chang C. "Androgen Receptor Interacting Proteins Co-Activators and Co-Repressors.". Androgens and Androgen Receptor: Mechanisms, Functions and Clinical Application.. Chang C. : Kluwer, USA., 2002. 91-138
2002
Heinlein C and Chang C. "Structural and Functional Analysis of the Androgen Receptor.". Androgens and Androgen Receptor: Mechanisms, Functions and Clinical Application.. Chang C. : Kluwer, USA., 2002. 17-56
2002
Heinlein C and Chang C. "Nongenomic Androgen Action.". Androgens and Androgen Receptor: Mechanisms, Functions and Clinical Application.. Chang C. : Kluwer, USA., 2002. 139-154
2002
Itami S. Inui S, Uno H, Pan H, Chang E, Takayasu S, Ye F, Imamura K, Seki T, Ideta R, Aoki H, Adachi K, Price V, Kurata S, Collins L, Heinlein C and Chang C. "Androgens in Dermatology: Hair Loss, Acne, and Other Diseases.". Androgens and Androgen Receptor: Mechanisms, Functions and Clinical Application. Chang C. : Kluwer, USA., 2002. 411-476
2000
Nishimura K, Sampson E, Yan S, Kim E, Wang X, Uemura H, Wang C, Fujimoto N, Kang H, Yeh S, and Chang C. ""Yeast two-hybrid screening of associated proteins and characterization of mutant androgen receptors."". Yeast Hybrid Technologies. (Zhu L and Hannon G ed).. : Eaton Publishing., 2000. 329-343
1998
Miyamoto H, Yeh S, Huang S-B, Fugimoto N, Hsiao P, Ting H, Inui S, Nishimura K, Wang C, Uemura H, Kang H, and Chang C. "The Androgen Receptor Coregulator ARA70.". Molecular Basis of Sex Hormone Receptor Function. Gronemeyer H, Fugymann U and Parczyk. : Springer, Berlin, 1998. 43-51
1996
Lin T, Lustig RH, and Chang C. ""The role of androgens-androgen receptor in immune system activity."". The Physiology of Immunity. (Marsh JA and Kendall MD eds). Boca Raton FL.: CRC Press,, 1996. pp. 263-276,
1996
Chang C, Lin T-M, Hsiao P, Su C, Riebe J, and Lin D-L. ""Androgen-responsive genes."". Pharmacology, Biology and Clinical Application of Androgens.. Basin C, and Swarlorf G. : Wiley-Liss, Inc., 1996. pp. 65-71,
1996
Su C-Y, Chang C, and Lai C-C. ""Induction of heat shock proteins by exercise.". Pharmacology in Exercise and Sports.. (Somani SM ed),. London.: CRC Press,, 1996. " pp. 147-167,
1989
Liao S, Chang C, Kokontis J, Popovich T, and Hiipakka RA. "Structure and intranuclear dynamics of androgen receptors.". The Steroid/Thyroid Hormone Receptor Family and Gene Regulation.. Gustafsson, JA., Eriksson, H. and Carlstedt-Duke, J.. : Congressdruck R. Bruckner, Berlin, Burkhauser Verlag Basel., 1989. 83-92
1989
Chang C, Lau L, Liao S, and Kokontis J. "Characterization of new members of steroid receptor superfamily." eds.) 183-195,". in The Steroid/Thyroid Hormone Receptor Family and Gene Regulation.. Gustafsson JA, Eriksson H, and Carlstedt-Duke J. : Congressdruck R. Bruckner, Berlin, Burkhauser Verlag Basel., 1989. 183-195
1987
Liao S, Chang C, Sorensen NS, Chang C-T, and Hiipakka RA. "Modulation of androgen receptor activity and the effect of androgens on gene expression for specific proteins.". Hormonal Therapy of Prostatic Disease: Basic and Clinical Aspects. Motta, M., and Serio, M.. : Medicom Europe, The Netherlands., 1987. 48-62
1985
Liao S, Chang C, Witte D, Saltzman AG, and Hiipakka RA. ""Modulation of androgen receptor and androgen-dependent enhancement and repression of protein synthesis."". Regulation of Androgen Action,. Bruchovsky N, Chapdelaine A, and Neumann F, eds.) ,. Berlin: Congressdruck R. Bruckner, 1985. pp.149-154
1985
Liao S, and Chang C. ""Cellular dynamics and control of androgen receptor activity."". Interaction of Steroid Hormone Receptors with DNA. Sluyser M, ed.. , Chichester, England.: Ellis Horwood Ltd. Publishers, 1985. pp.190-201,