Tim R. Mosmann, Ph.D.

Tim R. Mosmann, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 609
Rochester, NY 14642

Appointment: (585) 275-URMC (8762)

Professional Bio

Dr. Tim R. Mosmann is Director of the Human Immunology Center (HIC), and also serves as the Director and Michael and Angela Pichichero Director's Endowed Chair of the David H. Smith Center for Vaccine Biology and Immunology.



Dr. Mosmann received B.S. degrees in both Chemistry and Physiology, and in Microbiology, from the University of Natal and Rhodes University in South Africa. He subsequently emigrated to Canada and obtained his Ph.D. in Microbiology at the University of British Columbia. Research fellowships at the University of Toronto and University of Glasgow were followed by his appointment as an assistant professor at the University of Alberta. He then spent 8 years in industry, as a research scientist at DNAX Research Institute in Palo Alto, California - prior to rejoining the University of Alberta as Chairman of the Department of Immunology. In 1998, he was recruited to the University of Rochester.

Dr. Mosmann has made many important contributions to the field of Immunology, and is perhaps best known for his discovery, with his colleague Dr. Robert Coffman, of the TH1 and TH2 subsets of T lymphocytes, which determine whether the host response to infection will be characterized by a predominantly humoral immune response (TH2) or a predominantly cellular immune response (TH1). This discovery was a crucial event in our understanding of how the host immune response is regulated, and has fundamental implications for vaccine design and disease pathogenesis. Dr. Mosmann is recognized by the Institute for Scientific Information as a highly cited scientist, and has won many honours and awards for his unique contributions to understanding of the immune system. Note that "highly cited" scientists comprise less than 0.5% of all publishing researchers in science.

Patient Care Bio

Dr. Tim R. Mosmann is Director of the Human Immunology Center (HIC), and also serves as the Director and Michael and Angela Pichichero Director's Endowed Chair of the David H. Smith Center for Vaccine Biology and Immunology.



Dr. Mosmann received B.S. degrees in both Chemistry and Physiology, and in Microbiology, from the University of Natal and Rhodes University in South Africa. He subsequently emigrated to Canada and obtained his Ph.D. in Microbiology at the University of British Columbia. Research fellowships at the University of Toronto and University of Glasgow were followed by his appointment as an assistant professor at the University of Alberta. He then spent 8 years in industry, as a research scientist at DNAX Research Institute in Palo Alto, California - prior to rejoining the University of Alberta as Chairman of the Department of Immunology. In 1998, he was recruited to the University of Rochester.

Dr. Mosmann has made many important contributions to the field of Immunology, and is perhaps best known for his discovery, with his colleague Dr. Robert Coffman, of the TH1 and TH2 subsets of T lymphocytes, which determine whether the host response to infection will be characterized by a predominantly humoral immune response (TH2) or a predominantly cellular immune response (TH1). This discovery was a crucial event in our understanding of how the host immune response is regulated, and has fundamental implications for vaccine design and disease pathogenesis. Dr. Mosmann is recognized by the Institute for Scientific Information as a highly cited scientist, and has won many honours and awards for his unique contributions to understanding of the immune system. Note that "highly cited" scientists comprise less than 0.5% of all publishing researchers in science.

Awards & Honors (National)

Novartis Prize for Basic Immunology | Novartis | International 2013
Pillars of Immunology, 1989 article, IL-10 discovery | Journal of Immunology 2012
Thomson Reuters Citation Laureate | http://ip-science.thomsonreuters.com/nobel/categories/medicine/ 2011
Paul Ehrlich and Ludwig Darmstaedter Prize | Frankfurt, Germany 2008
Pillars of Immunology, 1986 paper, T cell subsets 2005
International Research Scholar, Howard Hughes Medical Institute. 1997 - 2001
William B. Coley Award, Cancer Research Institute (USA) 1997
NIH Fogarty Scholar-in-Residence, 12 months total 1996 - 1999
Fellow of the Royal Society of Canada 1995
Avery-Landsteiner Prize, German Society for Immunology 1994
Bernhard Cinader Lectureship, Canadian Society for Immunology. 1993
International Research Scholar, Howard Hughes Medical Institute. 1991 - 1996
Centennial Fellow, MRC of Canada. 1975 - 1977

Awards & Honors (Local)

ASTECH award for Outstanding Leadership in Alberta Science 1997

Current Appointments

Director - Center for Vaccine Biology and Immunology - Primary Administrative
Michael and Angela Pichichero Director in the David H. Smith Center for Vaccine Biology and Immunology - Center for Vaccine Biology and Immunology
Professor - Department of Microbiology and Immunology, Center for Vaccine Biology and Immunology (SMD) - Primary

Education

PhD | Microbiology | University of British Columbia1973
B. Sc. | Microbiology | Rhodes University1969
BS | Chemistry, and Physiology | University of Natal1968

Post-Doctoral Training & Residency

Glasgow University, Glasgow, Scotland; Immunology 1977
Hospital for Sick Children, Toronto; Immunology 1975