Bradford C. Berk, M.D., Ph.D.

Bradford C. Berk, M.D., Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 706
Rochester, NY 14642

Office: (585) 275-3647
Lab: (585) 276-9840
Administrative: (585) 275-3647

Books

2006
Berk BC, Korshunov VA. A Handbook of Mouse Models of Cardiovascular Disease. Xu Q., Eds.. : John Wiley & Sons Ltd., 2006.
2003
Berk BC. "Biology of the Vascular Wall in Hypertension". The Kidney. Brenner BM; Rector FC, Jr.. : W. B. Saunders, 2003.
2003
Berk BC; Wuthrich DA. "Lipids and Atherosclerosis". Cholesterol Lowering, A Practical Guide to Therapy. Abrams J., Eds.. : Oxford University Press, 2003. 20-35
2002
Berk BC. "Angiotensin II, Oxidative Stress, and Atherosclerosis". Harrison's Advances in Cardiology. Braunwald E.. : McGraw Hill, 2002. 6
2002
Berk BC. "Vascular Response to Injury". Thrombosis and Hemorrhage. Loscalzo J and Schafer A, Eds.. : Lippincott Williams & Wilkins, 2002.
2002
Hoefen RJ; Berk BC. "The Role of MAP Kinases in Endothelial Activation". Vascular Pharmacology. : Elsevier Science (US), 2002. 271-273
2001
Zheng-Gen J; Berk BC. "Signal Transduction Cascades Responsive to Oxidative Stress in the Vasculature". Cell and Molecular Responses to Stress. : Elsevier Science (US), 2001. 239-252
2001
Berk BC; Surapisitchat J; Yoshizumi M; Yan C; Hoefen R; Abe J. ""Atheroprotective Mechanisms of Fluid Shear Strsss: Nitric Oxide Independent Inhibition of Signal Transduction Mediated by Inflammatory Cytokines".". Vascular Endothelium - Source and Target of Inflammatory Mediators. Catravas JD et al, Eds.. : IOS Press, 2001. 115-125
2000
Abe J; Berk BC. "Reactive Oxygen Species Mediators Signal Transduction in Cardiovascular Disease". Antioxidants and Cardiovascular Disease. Tardif J-C; Bourassa MG, Eds.. : Kluwer Academic Publishers, 2000. 57-70
2000
Abe J; Yan C; Surapisitchat J; Berk BC. "Kinase Signaling in the Cardiovascular System". Heart Physiology and Pathophysiology. : Elsevier Science (US), 2000. 657-677
1999
Berk BC. "Angiotensin II, Oxidative Stress and Atherosclerosis". Harrison's On Line. Braunwald E.. : McGraw Hill, 1999.
1998
Traub O; Yan C; Berk BC. "In Vitro Stimulation of Shear Stress and Mitogen-activated Protein Kinase Respon". Mechanical Forces and the Endothelium. Lelkes, PI. London: Harwood Academic Publishers, 1998. 89
1998
Berk BC. "Regulation ofIntracelllar pH and Cell Volume". Hypertension Primer. Izzo JL, Jr.; Black H. : Lippincott Williams & Wilkins, 1998. 53
1998
Berk BC. "Biology of the Vascular Wall in Hypertension". The Kidney. Brenner BM; Rector FC, Jr.. : W. B. Saunders, 1998. 1943
1998
Berk BC. "Biology of the Vascular Wall in Hypertension". The Kidney. Brenner BM; Rector FC, Jr.. : W. B. Saunders, 1998. 1943
1997
Corson MA; Berk BC. "Tyrosine Kinases in the Regulation of Vascular Smooth Muscle Function". Molecular Biology of Cardiovascular Diseases. Marks AR; Taubman MB. New York, NY: Marcel Dekker, 1997. 291
1997
Berk BC. "Oxidative Stress and Vascular Remodeling". Vascular Remodeling: A New Approach to Restenosis. LaFont A; Topol E. Boston: Kluwer Academic Publishers, 1997. 277
1996
Berk BC. "Regulation of the Na+/H+ Exchanger in Vascular Smooth Muscle". The Na+/H+ Exchanger. Fliegel L. : Landes Bioscience, 1996.
1996
Berk BC; Duff JL; Marrero MB; Bernstein KE. "Angiotensin II Signal Transduction in Vascular Smooth Muscle". Endocrinology of the Vasculature. Sowers JR. : Humana Press, 1996. 187
1994
Berk BC; Alexander RW. "Biology of the Vascular Wall in Hypertension". The Kidney. Brenner BM and Rector FC Jr. : W. B. Saunders, 1994.
1993
Berk BC. "Cell Biology of Restenosis: Role of Angiotensin II in Neointimal Cell Proliferat". Interventional Cardiology: Future Directions. Vogel JHK and King III SB. Littleton, MA: Mosby, 1993.
1993
Berk BC; Alexander RW. "Rgulation of Intracellular pH and Cell Volume". Hypertension Primer. Izzo JL, Jr.; Black H. : Lippincott Williams & Wilkins, 1993.
1989
Mendelsohn ME; Berk BC. Heart Disease: Review and Assessment. Braunwald E.. Philadelphia, PA: W. B. Saunders, 1989.

Journal Articles

Showing all 293 journal articles available.

2014 Mar 28
Spindel ON, Burke RM, Yan C, Berk BC. "Thioredoxin-interacting protein is a biomechanical regulator of SRC activity: key role in endothelial cell stress fiber formation." Circulation research.. 2014 Mar 28; 114(7):1125-32. Epub 2014 Feb 10.
2014 Mar 1
Soe NN, Sowden M, Baskaran P, Kim Y, Nigro P, Smolock EM, Berk BC. "Acetylation of cyclophilin A is required for its secretion and vascular cell activation." Cardiovascular research. 2014 Mar 1; 101(3):444-53. Epub 2013 Nov 29.
2014 Feb
Majumder S, Sowden MP, Gerber SA, Thomas T, Christie CK, Mohan A, Yin G, Lord EM, Berk BC, Pang J. "G-protein-coupled receptor-2-interacting protein-1 is required for endothelial cell directional migration and tumor angiogenesis via cortactin-dependent lamellipodia formation." Arteriosclerosis, thrombosis, and vascular biology.. 2014 Feb; 34(2):419-26. Epub 2013 Nov 21.
2014 Jan 16
Wang L, Soe NN, Sowden M, Xu Y, Modjeski K, Baskaran P, Kim Y, Smolock EM, Morrell C, Berk BC. "Cyclophilin A is an important mediator of platelet function by regulating integrin ?IIb?3 bidirectional signalling." Thrombosis and haemostasis.. 2014 Jan 16; 111(5)Epub 2014 Jan 16.
2013 Sep
Soe NN, Sowden M, Baskaran P, Smolock EM, Kim Y, Nigro P, Berk BC. "Cyclophilin A is required for angiotensin II-induced p47phox translocation to caveolae in vascular smooth muscle cells." Arteriosclerosis, thrombosis, and vascular biology.. 2013 Sep; 33(9):2147-53. Epub 2013 Jul 11.
2013 Aug 6
Abe JI, Berk BC. "Atheroprone flow activation of the sterol regulatory element binding protein 2 and nod-like receptor protein 3 inflammasome mediates focal atherosclerosis." Circulation.. 2013 Aug 6; 128(6):579-82. Epub 2013 Jul 09.
2013 Jun 7
Abe J, Berk BC. "Cezanne paints inflammation by regulating ubiquitination." Circulation research.. 2013 Jun 7; 112(12):1526-8.
2013 May
Pang J, Xu X, Wang X, Majumder S, Wang J, Korshunov VA, Berk BC. "G-protein-coupled receptor kinase interacting protein-1 mediates intima formation by regulating vascular smooth muscle proliferation, apoptosis, and migration." Arteriosclerosis, thrombosis, and vascular biology.. 2013 May; 33(5):999-1005. Epub 2013 Feb 21.
2013 May
Smolock EM, Machleder DE, Korshunov VA, Berk BC. "Identification of a genetic locus on chromosome 11 that regulates leukocyte infiltration in mouse carotid artery." Arteriosclerosis, thrombosis, and vascular biology.. 2013 May; 33(5):1014-9. Epub 2013 Feb 28.
2013 Apr
Park Y, Park SY, Shi X, Pang J, Yan C, Berk BC. "Thioredoxin-interacting protein mediates sustained VEGFR2 signaling in endothelial cells required for angiogenesis." Arteriosclerosis, thrombosis, and vascular biology.. 2013 Apr; 33(4):737-43. Epub 2013 Feb 07.
2012 Nov 13
Smolock EM, Korshunov VA, Glazko G, Qiu X, Gerloff J, Berk B. "Ribosomal protein L17, RpL17, is an inhibitor of vascular smooth muscle growth and carotid intima formation." Circulation.. 2012 Nov 13; 126(20):2418-27. Epub 2012 Oct 12.
2012 May 24
Bell RD, Winkler EA, Singh I, Sagare AP, Deane R, Wu Z, Holtzman DM, Betsholtz C, Armulik A, Sallstrom J, Berk BC, Zlokovic BV. "Apolipoprotein E controls cerebrovascular integrity via cyclophilin A." Nature. 2012 May 24; 485(7399):512-6. Epub 2012 May 16.
2012 May
Spindel ON, Yan C, Berk BC. "Thioredoxin-interacting protein mediates nuclear-to-plasma membrane communication: role in vascular endothelial growth factor 2 signaling." Arteriosclerosis, thrombosis, and vascular biology.. 2012 May; 32(5):1264-70. Epub 2012 Feb 16.
2012 Mar 15
Spindel ON, World C, Berk B. "Thioredoxin interacting protein: redox dependent and independent regulatory mechanisms." Antioxidants & redox signaling.. 2012 Mar 15; 16(6):587-96. Epub 2011 Dec 20.
2012 Feb 17
Wang XQ, Nigro P, World C, Fujiwara K, Yan C, Berk BC. "Thioredoxin interacting protein promotes endothelial cell inflammation in response to disturbed flow by increasing leukocyte adhesion and repressing Kruppel-like factor 2." Circulation research.. 2012 Feb 17; 110(4):560-8. Epub 2012 Jan 19.
2012 Jan 3
Spindel ON, Berk BC. "Redox redux: protecting the ischemic myocardium." The Journal of clinical investigation.. 2012 Jan 3; 122(1):30-2. Epub 2011 Dec 27.
2012
Kim GY, Nigro P, Fujiwara K, Abe JI, Berk BC. "p62 binding to protein kinase C ? regulates tumor necrosis factor ?-induced apoptotic pathway in endothelial cells." Arteriosclerosis, thrombosis, and vascular biology.. 2012 32(12):2974-80. Epub 2012 Sep 27.
2011 Nov
Pang J, Xu X, Getman MR, Shi X, Belmonte SL, Michaloski H, Mohan A, Blaxall BC, Berk BC. "G protein coupled receptor kinase 2 interacting protein 1 (GIT1) is a novel regulator of mitochondrial biogenesis in heart." Journal of molecular and cellular cardiology. 2011 Nov; 51(5):769-76. Epub 2011 Jul 02.
2011 Sep 1
Nigro P, Abe JI, Berk B. "Flow shear stress and atherosclerosis: a matter of site specificity." Antioxidants & redox signaling.. 2011 Sep 1; 15(5):1405-14. Epub 2011 Apr 08.
2011 Aug 1
Satoh K, Berk BC, Shimokawa H. "Vascular-derived reactive oxygen species for homeostasis and diseases." Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society. 2011 Aug 1; 25(2):211-5. Epub 2011 May 03.
2011 Aug
Shi X, Yan C, Nadtochiy SM, Abe JI, Brookes PS, Berk BC. "p90 ribosomal S6 kinase regulates activity of the renin-angiotensin system: a pathogenic mechanism for ischemia-reperfusion injury." Journal of molecular and cellular cardiology. 2011 Aug; 51(2):272-5. Epub 2011 May 14.
2011 Aug
World C, Spindel ON, Berk BC. "Thioredoxin-interacting protein mediates TRX1 translocation to the plasma membrane in response to tumor necrosis factor-?: a key mechanism for vascular endothelial growth factor receptor-2 transactivation by reactive oxygen species." Arteriosclerosis, thrombosis, and vascular biology.. 2011 Aug; 31(8):1890-7. Epub 2011 Jun 02.
2011 May 30
Heo KS, Lee H, Nigro P, Thomas T, Le NT, Chang E, McClain C, Reinhart-King CA, King MR, Berk BC, Fujiwara K, Woo CH, Abe J. "PKC? mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation." The Journal of cell biology. 2011 May 30; 193(5):867-84.
2011 May
Satoh K, Nigro P, Zeidan A, Soe NN, Jaffré F, Oikawa M, O'Dell MR, Cui Z, Menon P, Lu Y, Mohan A, Yan C, Blaxall BC, Berk BC. "Cyclophilin A promotes cardiac hypertrophy in apolipoprotein E-deficient mice." Arteriosclerosis, thrombosis, and vascular biology.. 2011 May; 31(5):1116-23. Epub 2011 Feb 17.
2011 Jan 17
Nigro P, Satoh K, O'Dell MR, Soe NN, Cui Z, Mohan A, Abe JI, Alexis JD, Sparks JD, Berk BC. "Cyclophilin A is an inflammatory mediator that promotes atherosclerosis in apolipoprotein E-deficient mice." The Journal of experimental medicine.. 2011 Jan 17; 208(1):53-66. Epub 2010 Dec 20.
2010 Nov
Menon P, Yin G, Smolock EM, Zuscik MJ, Yan C, Berk BC. "GPCR kinase 2 interacting protein 1 (GIT1) regulates osteoclast function and bone mass." Journal of cellular physiology. 2010 Nov; 225(3):777-85.
2010 Nov
Satoh K, Shimokawa H, Berk BC. "Cyclophilin A: promising new target in cardiovascular therapy." Circulation journal : official journal of the Japanese Circulation Society. 2010 Nov; 74(11):2249-56. Epub 2010 Oct 15.
2010 Oct
Wang J, Yin G, Menon P, Pang J, Smolock EM, Yan C, Berk BC. "Phosphorylation of G protein-coupled receptor kinase 2-interacting protein 1 tyrosine 392 is required for phospholipase C-gamma activation and podosome formation in vascular smooth muscle cells." Arteriosclerosis, thrombosis, and vascular biology.. 2010 Oct; 30(10):1976-82. Epub 2010 Aug 05.
2010 Sep 16
Nigro P, Abe JI, Woo CH, Satoh K, McClain C, O'Dell MR, Lee H, Lim JH, Li JD, Heo KS, Fujiwara K, Berk BC. "PKCzeta decreases eNOS protein stability via inhibitory phosphorylation of ERK5." Blood.. 2010 Sep 16; 116(11):1971-9. Epub 2010 Jun 10.
2010 Jul
Cavet ME, Smolock EM, Menon P, Konishi A, Korshunov VA, Berk BC. "Gas6-Axl pathway: the role of redox-dependent association of Axl with nonmuscle myosin IIB." Hypertension.. 2010 Jul; 56(1):105-11. Epub 2010 May 17.
2010 May 25
Jeon KI, Xu X, Aizawa T, Lim JH, Jono H, Kwon DS, Abe JI, Berk BC, Li JD, Yan C. "Vinpocetine inhibits NF-kappaB-dependent inflammation via an IKK-dependent but PDE-independent mechanism." Proceedings of the National Academy of Sciences of the United States of America.. 2010 May 25; 107(21):9795-800. Epub 2010 May 06.
2010 Mar 4
Menon P, Deane R, Sagare A, Lane SM, Zarcone TJ, O'Dell MR, Yan C, Zlokovic BV, Berk BC. "Impaired spine formation and learning in GPCR kinase 2 interacting protein-1 (GIT1) knockout mice." Brain research. 2010 Mar 4; 1317:218-26. Epub 2010 Jan 04.
2010 Mar 1
Satoh K, Nigro P, Berk B. "Oxidative stress and vascular smooth muscle cell growth: a mechanistic linkage by cyclophilin A." Antioxidants & redox signaling.. 2010 Mar 1; 12(5):675-82.
2010 Jan
Zhang N, Cai W, Ma Y, Yin G, Nagel DJ, Berk BC. "GIT1 is a novel MEK1-ERK1/2 scaffold that localizes to focal adhesions." Cell biology international. 2010 Jan; 34(1):41-7. Epub 2009 Dec 16.
2009 Aug 11
Xie S, Lee YF, Kim E, Chen LM, Ni J, Fang LY, Liu S, Lin SJ, Abe JI, Berk B, Ho FM, Chang C. "TR4 nuclear receptor functions as a fatty acid sensor to modulate CD36 expression and foam cell formation." Proceedings of the National Academy of Sciences of the United States of America.. 2009 Aug 11; 106(32):13353-8. Epub 2009 Jul 28.
2009 Jun
Pan S, World CJ, Kovacs CJ, Berk BC. "Glucose 6-phosphate dehydrogenase is regulated through c-Src-mediated tyrosine phosphorylation in endothelial cells." Arteriosclerosis, thrombosis, and vascular biology.. 2009 Jun; 29(6):895-901. Epub 2009 Apr 09.
2009 Jun
Satoh K, Nigro P, Matoba T, O'Dell MR, Cui Z, Shi X, Mohan A, Yan C, Abe JI, Illig KA, Berk BC. "Cyclophilin A enhances vascular oxidative stress and the development of angiotensin II-induced aortic aneurysms." Nature medicine.. 2009 Jun; 15(6):649-56.
2009 Mar 24
Pang J, Hoefen R, Pryhuber GS, Wang J, Yin G, White RJ, Xu X, O'Dell MR, Mohan A, Michaloski H, Massett MP, Yan C, Berk BC. "G-protein-coupled receptor kinase interacting protein-1 is required for pulmonary vascular development." Circulation.. 2009 Mar 24; 119(11):1524-32. Epub 2009 Mar 09.
2009 Feb
Wang J, Taba Y, Pang J, Yin G, Yan C, Berk BC. "GIT1 mediates VEGF-induced podosome formation in endothelial cells: critical role for PLCgamma." Arteriosclerosis, thrombosis, and vascular biology.. 2009 Feb; 29(2):202-8. Epub 2008 Nov 20.
2009 Feb
Ibrahim J, Berk BC. "Flow-mediated vascular remodeling in hypertension: relation to hemodyamics." Stroke; a journal of cerebral circulation.. 2009 Feb; 40(2):582-90. Epub 2008 Dec 18.
2009 Jan 2
Alexis JD, Wang N, Che W, Lerner-Marmarosh N, Sahni A, Korshunov VA, Zou Y, Ding B, Yan C, Berk BC, Abe J. "Bcr kinase activation by angiotensin II inhibits peroxisome-proliferator-activated receptor gamma transcriptional activity in vascular smooth muscle cells." Circulation research.. 2009 Jan 2; 104(1):69-78. Epub 2008 Nov 20.
2009 Jan
Korshunov VA, Berk BC. "Genetic modifier loci linked to intima formation induced by low flow in the mouse carotid." Arteriosclerosis, thrombosis, and vascular biology.. 2009 Jan; 29(1):47-53. Epub 2008 Oct 23.
2009
Massett MP, Fan R, Berk BC. "Quantitative trait loci for exercise training responses in FVB/NJ and C57BL/6J mice." Physiological genomics. 2009 40(1):15-22. Epub 2009 Sep 29.
2009
Ibrahim, J, Berk BC. "Flow-Mediated Vascular Remodeling in Hypertension. Relation to Hemodyamics." Stroke. 2009; . Link
2009
Plekhanova O, Berk BC, Bashtrykov P, Brooks AI, Tkachuk V, Parfyonova Y. "Oligonucleotide microarrays reveal regulated genes related to inward arterial remodeling induced by urokinase plasminogen activator." Journal of vascular research. 2009 46(3):177-87. Epub 2008 Sep 24.
2008 Oct
Cavet ME, Pang J, Yin G, Berk BC. "An epidermal growth factor (EGF) -dependent interaction between GIT1 and sorting nexin 6 promotes degradation of the EGF receptor." FASEB journal : official publication of the Federation of American Societies for Experimental Biology.. 2008 Oct; 22(10):3607-16. Epub 2008 Jun 03.
2008 Jun 17
Satoh K, Matoba T, Suzuki J, O'Dell MR, Nigro P, Cui Z, Mohan A, Pan S, Li L, Jin ZG, Yan C, Abe J, Berk BC. "Cyclophilin A mediates vascular remodeling by promoting inflammation and vascular smooth muscle cell proliferation." Circulation.. 2008 Jun 17; 117(24):3088-98. Epub 2008 Jun 09.
2008 May 23
Li L, Tatake RJ, Natarajan K, Taba Y, Garin G, Tai C, Leung E, Surapisitchat J, Yoshizumi M, Yan C, Abe J, Berk BC. "Fluid shear stress inhibits TNF-mediated JNK activation via MEK5-BMK1 in endothelial cells." Biochemical and biophysical research communications.. 2008 May 23; 370(1):159-63. Epub 2008 Mar 19.
2008 May
Cavet ME, Smolock EM, Ozturk OH, World C, Pang J, Konishi A, Berk BC. "Gas6-axl receptor signaling is regulated by glucose in vascular smooth muscle cells." Arteriosclerosis, thrombosis, and vascular biology.. 2008 May; 28(5):886-91. Epub 2008 Feb 21.
2008 May
Pang J, Yan C, Natarajan K, Cavet ME, Massett MP, Yin G, Berk BC. "GIT1 mediates HDAC5 activation by angiotensin II in vascular smooth muscle cells." Arteriosclerosis, thrombosis, and vascular biology.. 2008 May; 28(5):892-8. Epub 2008 Feb 21.
2008 May
Korshunov VA, Berk BC. "Smooth muscle apoptosis and vascular remodeling." Current opinion in hematology. 2008 May; 15(3):250-4.
2008 Apr
Mathews MT, Berk BC. "PARP-1 inhibition prevents oxidative and nitrosative stress-induced endothelial cell death via transactivation of the VEGF receptor 2." Arteriosclerosis, thrombosis, and vascular biology.. 2008 Apr; 28(4):711-7. Epub 2008 Jan 31.
2008 Feb 26
Berk BC. "Atheroprotective signaling mechanisms activated by steady laminar flow in endothelial cells." Circulation.. 2008 Feb 26; 117(8):1082-9.
2008 Feb 1
Satoh K, Berk BC. "Circulating smooth muscle progenitor cells: novel players in plaque stability." Cardiovascular research. 2008 Feb 1; 77(3):445-7. Epub 2007 Dec 04.
2008
Reinhart-King, C.; Fujiwara, K.; Berk, B.C. "Chapter 2 physiologic stress-mediated signaling in the endothelium." Methods Enzymology. 2008; 443: 25-44. Link
2008
Reinhart-King CA, Fujiwara K, Berk BC. "Physiologic stress-mediated signaling in the endothelium." Methods in enzymology. 2008 443:25-44.
2007 Aug
Korshunov VA, Schwartz SM, Berk BC. "Vascular remodeling: hemodynamic and biochemical mechanisms underlying Glagov's phenomenon." Arteriosclerosis, thrombosis, and vascular biology.. 2007 Aug; 27(8):1722-8. Epub 2007 May 31.
2007 Jul 6
Garin G, Abe J, Mohan A, Lu W, Yan C, Newby AC, Rhaman A, Berk BC. "Flow antagonizes TNF-alpha signaling in endothelial cells by inhibiting caspase-dependent PKC zeta processing." Circulation research.. 2007 Jul 6; 101(1):97-105. Epub 2007 May 24.
2007 Jun
Wang J, Pan S, Berk BC. "Glutaredoxin mediates Akt and eNOS activation by flow in a glutathione reductase-dependent manner." Arteriosclerosis, thrombosis, and vascular biology.. 2007 Jun; 27(6):1283-8. Epub 2007 Apr 12.
2007 Mar
Berk BC, Fujiwara K, Lehoux S. "ECM remodeling in hypertensive heart disease." The Journal of clinical investigation.. 2007 Mar; 117(3):568-75.
2007 Feb 2
Pan S, Berk BC. "Glutathiolation regulates tumor necrosis factor-alpha-induced caspase-3 cleavage and apoptosis: key role for glutaredoxin in the death pathway." Circulation research.. 2007 Feb 2; 100(2):213-9. Epub 2006 Dec 21.
2007
Chen C, Korshunov VA, Massett MP, Yan C, Berk BC. "Impaired vasorelaxation in inbred mice is associated with alterations in both nitric oxide and super oxide pathways." Journal of vascular research. 2007 44(6):504-12. Epub 2007 Jul 30.
2007
Korshunov VA, Daul M, Massett MP, Berk BC. "Axl mediates vascular remodeling induced by deoxycorticosterone acetate-salt hypertension." Hypertension.. 2007 50(6):1057-62. Epub 2007 Oct 08.
2007
Berk BC. "Novel approaches to treat oxidative stress and cardiovascular diseases." Transactions of the American Clinical and Climatological Association. 2007 118:209-14.
2006 Nov
Barker TA, Massett MP, Korshunov VA, Mohan AM, Kennedy AJ, Berk BC. "Angiotensin II type 2 receptor expression after vascular injury: differing effects of angiotensin-converting enzyme inhibition and angiotensin receptor blockade." Hypertension.. 2006 Nov; 48(5):942-9. Epub 2006 Sep 18.
2006 Sep
Miano JM, Berk BC. "HDAC7 supports vascular integrity." Nature medicine.. 2006 Sep; 12(9):997-8.
2006 Sep
Plekhanova OS, Men'shikov MY, Bashtrykov PP, Berk BC, Tkachuk VA, Parfenova EV. "Urokinase induces ROS production in vascular smooth muscle cells." Bulletin of experimental biology and medicine. 2006 Sep; 142(3):304-7.
2006 Jun 9
Korshunov VA, Mohan AM, Georger MA, Berk BC. "Axl, a receptor tyrosine kinase, mediates flow-induced vascular remodeling." Circulation research.. 2006 Jun 9; 98(11):1446-52. Epub 2006 Apr 20.
2006 May 30
Maekawa N, Abe J, Shishido T, Itoh S, Ding B, Sharma VK, Sheu SS, Blaxall BC, Berk BC. "Inhibiting p90 ribosomal S6 kinase prevents (Na+)-H+ exchanger-mediated cardiac ischemia-reperfusion injury." Circulation.. 2006 May 30; 113(21):2516-23. Epub 2006 May 22.
2006 Apr 15
Hoefen RJ, Berk BC. "The multifunctional GIT family of proteins." Journal of cell science.. 2006 Apr 15; 119(Pt 8):1469-75.
2006 Apr 11
Itoh S, Ding B, Shishido T, Lerner-Marmarosh N, Wang N, Maekawa N, Berk BC, Takeishi Y, Yan C, Blaxall BC, Abe J. "Role of p90 ribosomal S6 kinase-mediated prorenin-converting enzyme in ischemic and diabetic myocardium." Circulation.. 2006 Apr 11; 113(14):1787-98. Epub 2006 Apr 03.
2006 Apr
Menshikov M, Plekhanova O, Cai H, Chalupsky K, Parfyonova Y, Bashtrikov P, Tkachuk V, Berk BC. "Urokinase plasminogen activator stimulates vascular smooth muscle cell proliferation via redox-dependent pathways." Arteriosclerosis, thrombosis, and vascular biology.. 2006 Apr; 26(4):801-7. Epub 2006 Feb 02.
2006 Mar 31
Nagel DJ, Aizawa T, Jeon KI, Liu W, Mohan A, Wei H, Miano JM, Florio VA, Gao P, Korshunov VA, Berk BC, Yan C. "Role of nuclear Ca2+/calmodulin-stimulated phosphodiesterase 1A in vascular smooth muscle cell growth and survival." Circulation research.. 2006 Mar 31; 98(6):777-84. Epub 2006 Mar 02.
2006 Mar 31
Suzuki J, Jin ZG, Meoli DF, Matoba T, Berk BC. "Cyclophilin A is secreted by a vesicular pathway in vascular smooth muscle cells." Circulation research.. 2006 Mar 31; 98(6):811-7. Epub 2006 Mar 09.
2006 Feb
Korshunov VA, Nikonenko TA, Tkachuk VA, Brooks A, Berk BC. "Interleukin-18 and macrophage migration inhibitory factor are associated with increased carotid intima-media thickening." Arteriosclerosis, thrombosis, and vascular biology.. 2006 Feb; 26(2):295-300. Epub 2005 Nov 17.
2006 Feb
Berk BC, Korshunov VA. "Genetic determinants of vascular remodelling." The Canadian journal of cardiology. 2006 Feb; 22 Suppl B:6B-11B.
2006 Jan 6
Shen WL, Gao PJ, Che ZQ, Ji KD, Yin M, Yan C, Berk BC, Zhu DL. "NAD(P)H oxidase-derived reactive oxygen species regulate angiotensin-II induced adventitial fibroblast phenotypic differentiation." Biochemical and biophysical research communications.. 2006 Jan 6; 339(1):337-43. Epub 2005 Nov 15.
2006 Jan
Ibrahim J, Berk BC, Hughes AD. "Comparison of simultaneous measurements of blood pressure by tail-cuff and carotid arterial methods in conscious spontaneously hypertensive and Wistar-Kyoto rats." Clinical and experimental hypertension (New York, N.Y. : 1993). 2006 Jan; 28(1):57-72.
2006
Natarajan K, Berk BC. "Crosstalk coregulation mechanisms of G protein-coupled receptors and receptor tyrosine kinases." Methods in molecular biology.. 2006 332:51-77.
2006
World CJ, Yamawaki H, Berk BC. "Thioredoxin in the cardiovascular system." Journal of molecular medicine (Berlin, Germany). 2006 84(12):997-1003. Epub 2006 Oct 05.
2006
Garin G, Berk BC. "Flow-mediated signaling modulates endothelial cell phenotype." Endothelium : journal of endothelial cell research. 2006 13(6):375-84.
2005 Nov 11
Garin G, Mathews M, Berk BC. "Tissue-resident bone marrow-derived progenitor cells: key players in hypoxia-induced angiogenesis." Circulation research.. 2005 Nov 11; 97(10):955-7.
2005 Oct 11
Ding B, Abe J, Wei H, Xu H, Che W, Aizawa T, Liu W, Molina CA, Sadoshima J, Blaxall BC, Berk BC, Yan C. "A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis." Proceedings of the National Academy of Sciences of the United States of America.. 2005 Oct 11; 102(41):14771-6. Epub 2005 Sep 26.
2005 Sep 20
Watanabe T, Suzuki J, Yamawaki H, Sharma VK, Sheu SS, Berk BC. "Losartan metabolite EXP3179 activates Akt and endothelial nitric oxide synthase via vascular endothelial growth factor receptor-2 in endothelial cells: angiotensin II type 1 receptor-independent effects of EXP3179." Circulation.. 2005 Sep 20; 112(12):1798-805.
2005 Sep
Giles TD, Berk BC, Black HR, Cohn JN, Kostis JB, Izzo JL, Weber MA. "Expanding the definition and classification of hypertension." Journal of clinical hypertension (Greenwich, Conn.). 2005 Sep; 7(9):505-12.
2005 Aug 19
Tai LK, Zheng Q, Pan S, Jin ZG, Berk BC. "Flow activates ERK1/2 and endothelial nitric oxide synthase via a pathway involving PECAM1, SHP2, and Tie2." The Journal of biological chemistry.. 2005 Aug 19; 280(33):29620-4. Epub 2005 Jun 28.
2005 Jul 29
Yin G, Zheng Q, Yan C, Berk BC. "GIT1 is a scaffold for ERK1/2 activation in focal adhesions." The Journal of biological chemistry.. 2005 Jul 29; 280(30):27705-12. Epub 2005 May 27.
2005 Jun 10
Pi X, Garin G, Xie L, Zheng Q, Wei H, Abe J, Yan C, Berk BC. "BMK1/ERK5 is a novel regulator of angiogenesis by destabilizing hypoxia inducible factor 1alpha." Circulation research.. 2005 Jun 10; 96(11):1145-51. Epub 2005 May 05.
2005 May 17
Ding B, Abe J, Wei H, Huang Q, Walsh RA, Molina CA, Zhao A, Sadoshima J, Blaxall BC, Berk BC, Yan C. "Functional role of phosphodiesterase 3 in cardiomyocyte apoptosis: implication in heart failure." Circulation.. 2005 May 17; 111(19):2469-76. Epub 2005 May 02.
2005 Apr 1
Jin ZG, Wong C, Wu J, Berk BC. "Flow shear stress stimulates Gab1 tyrosine phosphorylation to mediate protein kinase B and endothelial nitric-oxide synthase activation in endothelial cells." The Journal of biological chemistry.. 2005 Apr 1; 280(13):12305-9. Epub 2005 Jan 21.
2005 Apr 1
Blaxall BC, Miano JM, Berk BC. "Angiotensin II: a devious activator of mineralocorticoid receptor-dependent gene expression." Circulation research.. 2005 Apr 1; 96(6):610-1.
2005 Apr
Massett MP, Berk BC. "Strain-dependent differences in responses to exercise training in inbred and hybrid mice." American journal of physiology. Regulatory, integrative and comparative physiology. 2005 Apr; 288(4):R1006-13. Epub 2004 Dec 23.
2005 Mar
Yamawaki H, Berk BC. "Thioredoxin: a multifunctional antioxidant enzyme in kidney, heart and vessels." Current opinion in nephrology and hypertension. 2005 Mar; 14(2):149-53.
2005 Mar
Yamawaki H, Pan S, Lee RT, Berk BC. "Fluid shear stress inhibits vascular inflammation by decreasing thioredoxin-interacting protein in endothelial cells." The Journal of clinical investigation.. 2005 Mar; 115(3):733-8.
2005 Feb
Watanabe T, Barker TA, Berk BC. "Angiotensin II and the endothelium: diverse signals and effects." Hypertension.. 2005 Feb; 45(2):163-9. Epub 2005 Jan 03.
2005 Jan
Kim D, Aizawa T, Wei H, Pi X, Rybalkin SD, Berk BC, Yan C. "Angiotensin II increases phosphodiesterase 5A expression in vascular smooth muscle cells: a mechanism by which angiotensin II antagonizes cGMP signaling." Journal of molecular and cellular cardiology. 2005 Jan; 38(1):175-84. Epub 2004 Dec 08.
2005
Velarde G, Berk BC. "Role of hypertension in the metabolic syndrome: who is affected?" Current hypertension reports. 2005 7(6):418-26.
2004 Nov 19
Lungu AO, Jin ZG, Yamawaki H, Tanimoto T, Wong C, Berk BC. "Cyclosporin A inhibits flow-mediated activation of endothelial nitric-oxide synthase by altering cholesterol content in caveolae." The Journal of biological chemistry.. 2004 Nov 19; 279(47):48794-800. Epub 2004 Sep 20.
2004 Nov 15
Narins CR, Lin DA, Burton PB, Jin ZG, Berk BC. "Interleukin-18 and interleukin-18 binding protein levels before and after percutaneous coronary intervention in patients with and without recent myocardial infarction." The American journal of cardiology.. 2004 Nov 15; 94(10):1285-7.
2004 Oct
Akaike M, Che W, Marmarosh NL, Ohta S, Osawa M, Ding B, Berk BC, Yan C, Abe J. "The hinge-helix 1 region of peroxisome proliferator-activated receptor gamma1 (PPARgamma1) mediates interaction with extracellular signal-regulated kinase 5 and PPARgamma1 transcriptional activation: involvement in flow-induced PPARgamma activation in endothelial cells." Molecular and cellular biology. 2004 Oct; 24(19):8691-704.
2004 Oct
Melaragno MG, Cavet ME, Yan C, Tai LK, Jin ZG, Haendeler J, Berk BC. "Gas6 inhibits apoptosis in vascular smooth muscle: role of Axl kinase and Akt." Journal of molecular and cellular cardiology. 2004 Oct; 37(4):881-7.
2004 Jul 13
Korshunov VA, Berk BC. "Strain-dependent vascular remodeling: the "Glagov phenomenon" is genetically determined." Circulation.. 2004 Jul 13; 110(2):220-6. Epub 2004 Jun 28.
2004 Jul 9
Osawa M, Itoh S, Ohta S, Huang Q, Berk BC, Marmarosh NL, Che W, Ding B, Yan C, Abe J. "ERK1/2 associates with the c-Met-binding domain of growth factor receptor-bound protein 2 (Grb2)-associated binder-1 (Gab1): role in ERK1/2 and early growth response factor-1 (Egr-1) nuclear accumulation." The Journal of biological chemistry.. 2004 Jul 9; 279(28):29691-9. Epub 2004 Apr 12.
2004 Jul 2
Konishi A, Aizawa T, Mohan A, Korshunov VA, Berk BC. "Hydrogen peroxide activates the Gas6-Axl pathway in vascular smooth muscle cells." The Journal of biological chemistry.. 2004 Jul 2; 279(27):28766-70. Epub 2004 Apr 28.
2004 Jul
Jin ZG, Lungu AO, Xie L, Wang M, Wong C, Berk BC. "Cyclophilin A is a proinflammatory cytokine that activates endothelial cells." Arteriosclerosis, thrombosis, and vascular biology.. 2004 Jul; 24(7):1186-91. Epub 2004 May 06.
2004 May
Jin ZG, Berk BC. "SOXF: redox mediators of vascular smooth muscle cell growth." Heart (British Cardiac Society). 2004 May; 90(5):488-90.
2004 Apr 30
van Nieuw Amerongen GP, Natarajan K, Yin G, Hoefen RJ, Osawa M, Haendeler J, Ridley AJ, Fujiwara K, van Hinsbergh VW, Berk BC. "GIT1 mediates thrombin signaling in endothelial cells: role in turnover of RhoA-type focal adhesions." Circulation research.. 2004 Apr 30; 94(8):1041-9. Epub 2004 Mar 11.
2004 Apr 30
Tanimoto T, Lungu AO, Berk BC. "Sphingosine 1-phosphate transactivates the platelet-derived growth factor beta receptor and epidermal growth factor receptor in vascular smooth muscle cells." Circulation research.. 2004 Apr 30; 94(8):1050-8. Epub 2004 Mar 25.
2004 Apr
Natarajan K, Yin G, Berk BC. "Scaffolds direct Src-specific signaling in response to angiotensin II: new roles for Cas and GIT1." Molecular pharmacology.. 2004 Apr; 65(4):822-5.
2004 Mar 5
Zheng Q, Yin G, Yan C, Cavet M, Berk BC. "14-3-3beta binds to big mitogen-activated protein kinase 1 (BMK1/ERK5) and regulates BMK1 function." The Journal of biological chemistry.. 2004 Mar 5; 279(10):8787-91. Epub 2003 Dec 16.
2004 Feb 20
Pi X, Yan C, Berk BC. "Big mitogen-activated protein kinase (BMK1)/ERK5 protects endothelial cells from apoptosis." Circulation research.. 2004 Feb 20; 94(3):362-9. Epub 2003 Dec 11.
2004 Jan
Yin G, Haendeler J, Yan C, Berk BC. "GIT1 functions as a scaffold for MEK1-extracellular signal-regulated kinase 1 and 2 activation by angiotensin II and epidermal growth factor." Molecular and cellular biology. 2004 Jan; 24(2):875-85.
2004
Korshunov VA, Massett MP, Carey RM, Berk BC. "Role of Angiotensin-converting enzyme and neutral endopeptidase in flow-dependent remodeling." Journal of vascular research. 2004 41(2):148-56. Epub 2004 Mar 03.
2004
Berk BC, Bisognano JD. "VALUE in hypertension treatment." Current hypertension reports. 2004 6(6):411-3.
2004
Korshunov VA, Solomatina MA, Plekhanova OS, Parfyonova YV, Tkachuk VA, Berk BC. "Plasminogen activator expression correlates with genetic differences in vascular remodeling." Journal of vascular research. 2004 41(6):481-90. Epub 2004 Oct 28.
2004
Jin ZG, Berk BC. "Role of secreted oxidative stress-induced factors (SOXFs) in the pathogenesis of atherosclerosis." Archives des maladies du coeur et des vaisseaux. 2004 97(12):1256-9.
2003 Nov 28
Yamawaki H, Haendeler J, Berk BC. "Thioredoxin: a key regulator of cardiovascular homeostasis." Circulation research.. 2003 Nov 28; 93(11):1029-33.
2003 Oct 1
Lerner-Marmarosh N, Yoshizumi M, Che W, Surapisitchat J, Kawakatsu H, Akaike M, Ding B, Huang Q, Yan C, Berk BC, Abe J. "Inhibition of tumor necrosis factor-[alpha]-induced SHP-2 phosphatase activity by shear stress: a mechanism to reduce endothelial inflammation." Arteriosclerosis, thrombosis, and vascular biology.. 2003 Oct 1; 23(10):1775-81. Epub 2003 Aug 28.
2003 Sep 30
Yamawaki H, Lehoux S, Berk BC. "Chronic physiological shear stress inhibits tumor necrosis factor-induced proinflammatory responses in rabbit aorta perfused ex vivo." Circulation.. 2003 Sep 30; 108(13):1619-25. Epub 2003 Sep 08.
2003 Sep 12
Konishi A, Berk BC. "Epidermal growth factor receptor transactivation is regulated by glucose in vascular smooth muscle cells." The Journal of biological chemistry.. 2003 Sep 12; 278(37):35049-56. Epub 2003 Jun 26.
2003 Sep 5
Aizawa T, Wei H, Miano JM, Abe J, Berk BC, Yan C. "Role of phosphodiesterase 3 in NO/cGMP-mediated antiinflammatory effects in vascular smooth muscle cells." Circulation research.. 2003 Sep 5; 93(5):406-13. Epub 2003 Aug 14.
2003 Aug 22
Jin ZG, Ueba H, Tanimoto T, Lungu AO, Frame MD, Berk BC. "Ligand-independent activation of vascular endothelial growth factor receptor 2 by fluid shear stress regulates activation of endothelial nitric oxide synthase." Circulation research.. 2003 Aug 22; 93(4):354-63. Epub 2003 Jul 31.
2003 Jun
Yin G, Yan C, Berk BC. "Angiotensin II signaling pathways mediated by tyrosine kinases." The international journal of biochemistry & cell biology. 2003 Jun; 35(6):780-3.
2003 May 16
Cavet ME, Lehoux S, Berk BC. "14-3-3beta is a p90 ribosomal S6 kinase (RSK) isoform 1-binding protein that negatively regulates RSK kinase activity." The Journal of biological chemistry.. 2003 May 16; 278(20):18376-83. Epub 2003 Mar 04.
2003 May 16
Ibrahim J, Miyashiro JK, Berk BC. "Shear stress is differentially regulated among inbred rat strains." Circulation research.. 2003 May 16; 92(9):1001-9. Epub 2003 Apr 03.
2003 May 6
Berk BC. "Angiotensin type 2 receptor (AT2R): a challenging twin." Science's STKE : signal transduction knowledge environment. 2003 May 6; 2003(181):PE16. Epub 2003 May 06.
2003 May
Ogata Y, Takahashi M, Ueno S, Takeuchi K, Okada T, Mano H, Ookawara S, Ozawa K, Berk BC, Ikeda U, Shimada K, Kobayashi E. "Antiapoptotic effect of endothelin-1 in rat cardiomyocytes in vitro." Hypertension.. 2003 May; 41(5):1156-63. Epub 2003 Mar 31.
2003 Mar
Yoshizumi M, Abe J, Tsuchiya K, Berk BC, Tamaki T. "Stress and vascular responses: atheroprotective effect of laminar fluid shear stress in endothelial cells: possible role of mitogen-activated protein kinases." Journal of pharmacological sciences. 2003 Mar; 91(3):172-6.
2003 Jan 1
Yan C, Kim D, Aizawa T, Berk BC. "Functional interplay between angiotensin II and nitric oxide: cyclic GMP as a key mediator." Arteriosclerosis, thrombosis, and vascular biology.. 2003 Jan 1; 23(1):26-36.
2003
Haendeler J, Yin G, Hojo Y, Saito Y, Melaragno M, Yan C, Sharma VK, Heller M, Aebersold R, Berk BC. "GIT1 mediates Src-dependent activation of phospholipase Cgamma by angiotensin II and epidermal growth factor." The Journal of biological chemistry.. 2003 278(50):49936-44. Epub 2003 Sep 30.
2003
Korshunov VA, Berk BC. "Flow-induced vascular remodeling in the mouse: a model for carotid intima-media thickening." Arteriosclerosis, thrombosis, and vascular biology.. 2003 23(12):2185-91. Epub 2003 Oct 23.
2002 Nov 8
Tanimoto T, Jin ZG, Berk BC. "Transactivation of vascular endothelial growth factor (VEGF) receptor Flk-1/KDR is involved in sphingosine 1-phosphate-stimulated phosphorylation of Akt and endothelial nitric-oxide synthase (eNOS)." The Journal of biological chemistry.. 2002 Nov 8; 277(45):42997-3001. Epub 2002 Sep 10.
2002 Nov 1
Tai LK, Okuda M, Abe J, Yan C, Berk BC. "Fluid shear stress activates proline-rich tyrosine kinase via reactive oxygen species-dependent pathway." Arteriosclerosis, thrombosis, and vascular biology.. 2002 Nov 1; 22(11):1790-6.
2002 Oct 18
Hojo Y, Saito Y, Tanimoto T, Hoefen RJ, Baines CP, Yamamoto K, Haendeler J, Asmis R, Berk BC. "Fluid shear stress attenuates hydrogen peroxide-induced c-Jun NH2-terminal kinase activation via a glutathione reductase-mediated mechanism." Circulation research.. 2002 Oct 18; 91(8):712-8.
2002 Oct
Haendeler J, Hoffmann J, Tischler V, Berk BC, Zeiher AM, Dimmeler S. "Redox regulatory and anti-apoptotic functions of thioredoxin depend on S-nitrosylation at cysteine 69." Nature cell biology. 2002 Oct; 4(10):743-9.
2002 Aug 9
Huang Q, Lerner-Marmarosh N, Che W, Ohta S, Osawa M, Yoshizumi M, Glassman M, Yan C, Berk BC, Abe J. "The novel role of the C-terminal region of SHP-2. Involvement of Gab1 and SHP-2 phosphatase activity in Elk-1 activation." The Journal of biological chemistry.. 2002 Aug 9; 277(32):29330-41. Epub 2002 May 14.
2002 Jul 12
Abe J, Berk BC. "Hypoxia and HIF-1alpha stability: another stress-sensing mechanism for Shc." Circulation research.. 2002 Jul 12; 91(1):4-6.
2002 Jun 28
Saito Y, Hojo Y, Tanimoto T, Abe J, Berk BC. "Protein kinase C-alpha and protein kinase C-epsilon are required for Grb2-associated binder-1 tyrosine phosphorylation in response to platelet-derived growth factor." The Journal of biological chemistry.. 2002 Jun 28; 277(26):23216-22. Epub 2002 Apr 08.
2002 Jun 14
Che W, Lerner-Marmarosh N, Huang Q, Osawa M, Ohta S, Yoshizumi M, Glassman M, Lee JD, Yan C, Berk BC, Abe J. "Insulin-like growth factor-1 enhances inflammatory responses in endothelial cells: role of Gab1 and MEKK3 in TNF-alpha-induced c-Jun and NF-kappaB activation and adhesion molecule expression." Circulation research.. 2002 Jun 14; 90(11):1222-30.
2002 Jun
Frame MD, Fox RJ, Kim D, Mohan A, Berk BC, Yan C. "Diminished arteriolar responses in nitrate tolerance involve ROS and angiotensin II." American journal of physiology. Heart and circulatory physiology. 2002 Jun; 282(6):H2377-85.
2002 May
Hoefen RJ, Berk BC. "The role of MAP kinases in endothelial activation." Vascular pharmacology. 2002 May; 38(5):271-3.
2002 Apr
Saito Y, Berk BC. "Angiotensin II-mediated signal transduction pathways." Current hypertension reports. 2002 Apr; 4(2):167-71.
2002 Apr
Berk BC, Min W, Yan C, Surapisitchat J, Liu Y, Hoefen R. "Atheroprotective Mechanisms Activated by Fluid Shear Stress in Endothelial Cells." Drug news & perspectives. 2002 Apr; 15(3):133-139.
2002 Jan
Takeishi Y, Huang Q, Abe J, Che W, Lee JD, Kawakatsu H, Hoit BD, Berk BC, Walsh RA. "Activation of mitogen-activated protein kinases and p90 ribosomal S6 kinase in failing human hearts with dilated cardiomyopathy." Cardiovascular research. 2002 Jan; 53(1):131-7.
2002
Pi X, Yan C, Kim D, Chen J, Berk BC. "Differential expression of genes from nitrate-tolerant rat aorta." Journal of vascular research. 2002 39(4):304-10.
2001 Nov 6
Kim D, Rybalkin SD, Pi X, Wang Y, Zhang C, Munzel T, Beavo JA, Berk BC, Yan C. "Upregulation of phosphodiesterase 1A1 expression is associated with the development of nitrate tolerance." Circulation.. 2001 Nov 6; 104(19):2338-43.
2001 Nov
Takeishi Y, Huang Q, Wang T, Glassman M, Yoshizumi M, Baines CP, Lee JD, Kawakatsu H, Che W, Lerner-Marmarosh N, Zhang C, Yan C, Ohta S, Walsh RA, Berk BC, Abe J. "Src family kinase and adenosine differentially regulate multiple MAP kinases in ischemic myocardium: modulation of MAP kinases activation by ischemic preconditioning." Journal of molecular and cellular cardiology. 2001 Nov; 33(11):1989-2005.
2001 Oct
Saito Y, Haendeler J, Hojo Y, Yamamoto K, Berk BC. "Receptor heterodimerization: essential mechanism for platelet-derived growth factor-induced epidermal growth factor receptor transactivation." Molecular and cellular biology. 2001 Oct; 21(19):6387-94.
2001 Sep 18
Che W, Abe J, Yoshizumi M, Huang Q, Glassman M, Ohta S, Melaragno MG, Poppa V, Yan C, Lerner-Marmarosh N, Zhang C, Wu Y, Arlinghaus R, Berk BC. "p160 Bcr mediates platelet-derived growth factor activation of extracellular signal-regulated kinase in vascular smooth muscle cells." Circulation.. 2001 Sep 18; 104(12):1399-406.
2001 Sep
Takeishi Y, Huang Q, Abe J, Glassman M, Che W, Lee JD, Kawakatsu H, Lawrence EG, Hoit BD, Berk BC, Walsh RA. "Src and multiple MAP kinase activation in cardiac hypertrophy and congestive heart failure under chronic pressure-overload: comparison with acute mechanical stretch." Journal of molecular and cellular cardiology. 2001 Sep; 33(9):1637-48.
2001 Jul
Berk BC. "Vascular smooth muscle growth: autocrine growth mechanisms." Physiological reviews.. 2001 Jul; 81(3):999-1030.
2001 May 22
Surapisitchat J, Hoefen RJ, Pi X, Yoshizumi M, Yan C, Berk BC. "Fluid shear stress inhibits TNF-alpha activation of JNK but not ERK1/2 or p38 in human umbilical vein endothelial cells: Inhibitory crosstalk among MAPK family members." Proceedings of the National Academy of Sciences of the United States of America.. 2001 May 22; 98(11):6476-81. Epub 2001 May 15.
2001 May 11
Chen K, Vita JA, Berk BC, Keaney JF. "c-Jun N-terminal kinase activation by hydrogen peroxide in endothelial cells involves SRC-dependent epidermal growth factor receptor transactivation." The Journal of biological chemistry.. 2001 May 11; 276(19):16045-50. Epub 2001 Feb 27.
2001 May 11
Lehoux S, Abe Ji , Florian JA, Berk BC. "14-3-3 Binding to Na+/H+ exchanger isoform-1 is associated with serum-dependent activation of Na+/H+ exchange." The Journal of biological chemistry.. 2001 May 11; 276(19):15794-800. Epub 2001 Feb 13.
2001 May
Miano JM, Berk BC. "Retinoids: new insight into smooth muscle cell growth inhibition." Arteriosclerosis, thrombosis, and vascular biology.. 2001 May; 21(5):724-6.
2001 Apr 6
Yan C, Luo H, Lee JD, Abe J, Berk BC. "Molecular cloning of mouse ERK5/BMK1 splice variants and characterization of ERK5 functional domains." The Journal of biological chemistry.. 2001 Apr 6; 276(14):10870-8. Epub 2001 Jan 03.
2001 Apr
Liu Y, Yin G, Surapisitchat J, Berk BC, Min W. "Laminar flow inhibits TNF-induced ASK1 activation by preventing dissociation of ASK1 from its inhibitor 14-3-3." The Journal of clinical investigation.. 2001 Apr; 107(7):917-23.
2001 Jan
Saito Y, Berk BC. "Transactivation: a novel signaling pathway from angiotensin II to tyrosine kinase receptors." Journal of molecular and cellular cardiology. 2001 Jan; 33(1):3-7.
2001
Abe JI, Che W, Yoshizumi M, Huang Q, Glassman M, Ohta S, Wu Y, Arlinghaus R, Berk BC. "Bcr in vascular smooth muscle cells involvement of Ras and Raf-1 activation by Bcr." Annals of the New York Academy of Sciences.. 2001 947:341-3.
2001
Berk BC, Abe JI, Min W, Surapisitchat J, Yan C. "Endothelial atheroprotective and anti-inflammatory mechanisms." Annals of the New York Academy of Sciences.. 2001 947:93-109; discussion 109-11.
2000 Nov 24
Haendeler J, Berk BC. "Angiotensin II mediated signal transduction. Important role of tyrosine kinases." Regulatory peptides. 2000 Nov 24; 95(1-3):1-7.
2000 Nov 10
Ou H, Haendeler J, Aebly MR, Kelly LA, Cholewa BC, Koike G, Kwitek-Black A, Jacob HJ, Berk BC, Miano JM. "Retinoic acid-induced tissue transglutaminase and apoptosis in vascular smooth muscle cells." Circulation research.. 2000 Nov 10; 87(10):881-7.
2000 Oct 27
Jin ZG, Melaragno MG, Liao DF, Yan C, Haendeler J, Suh YA, Lambeth JD, Berk BC. "Cyclophilin A is a secreted growth factor induced by oxidative stress." Circulation research.. 2000 Oct 27; 87(9):789-96.
2000 Sep 1
Miano JM, Berk BC. "Retinoids: versatile biological response modifiers of vascular smooth muscle phenotype." Circulation research.. 2000 Sep 1; 87(5):355-62.
2000 Jun
Berk BC, Haendeler J, Sottile J. "Angiotensin II, atherosclerosis, and aortic aneurysms." The Journal of clinical investigation.. 2000 Jun; 105(11):1525-6.
2000 May 26
Heeneman S, Haendeler J, Saito Y, Ishida M, Berk BC. "Angiotensin II induces transactivation of two different populations of the platelet-derived growth factor beta receptor. Key role for the p66 adaptor protein Shc." The Journal of biological chemistry.. 2000 May 26; 275(21):15926-32.
2000 Apr 21
Yoshizumi M, Abe J, Haendeler J, Huang Q, Berk BC. "Src and Cas mediate JNK activation but not ERK1/2 and p38 kinases by reactive oxygen species." The Journal of biological chemistry.. 2000 Apr 21; 275(16):11706-12.
2000 Apr 14
Haendeler J, Ishida M, Hunyady L, Berk BC. "The third cytoplasmic loop of the angiotensin II type 1 receptor exerts differential effects on extracellular signal-regulated kinase (ERK1/ERK2) and apoptosis via Ras- and Rap1-dependent pathways." Circulation research.. 2000 Apr 14; 86(7):729-36.
2000 Mar 31
Abe J, Baines CP, Berk BC. "Role of mitogen-activated protein kinases in ischemia and reperfusion injury : the good and the bad." Circulation research.. 2000 Mar 31; 86(6):607-9.
2000 Jan 21
Abe J, Okuda M, Huang Q, Yoshizumi M, Berk BC. "Reactive oxygen species activate p90 ribosomal S6 kinase via Fyn and Ras." The Journal of biological chemistry.. 2000 Jan 21; 275(3):1739-48.
2000 Jan 7
Liao DF, Jin ZG, Baas AS, Daum G, Gygi SP, Aebersold R, Berk BC. "Purification and identification of secreted oxidative stress-induced factors from vascular smooth muscle cells." The Journal of biological chemistry.. 2000 Jan 7; 275(1):189-96.
1999 Nov
Melaragno MG, Fridell YW, Berk BC. "The Gas6/Axl system: a novel regulator of vascular cell function." Trends in cardiovascular medicine. 1999 Nov; 9(8):250-3.
1999 Oct 15
Gallis B, Corthals GL, Goodlett DR, Ueba H, Kim F, Presnell SR, Figeys D, Harrison DG, Berk BC, Aebersold R, Corson MA. "Identification of flow-dependent endothelial nitric-oxide synthase phosphorylation sites by mass spectrometry and regulation of phosphorylation and nitric oxide production by the phosphatidylinositol 3-kinase inhibitor LY294002." The Journal of biological chemistry.. 1999 Oct 15; 274(42):30101-8.
1999 Oct
Miano JM, Berk BC. "NAB2: a transcriptional brake for activated gene expression in the vessel wall?" The American journal of pathology.. 1999 Oct; 155(4):1009-12.
1999 Sep 17
Okuda M, Takahashi M, Suero J, Murry CE, Traub O, Kawakatsu H, Berk BC. "Shear stress stimulation of p130(cas) tyrosine phosphorylation requires calcium-dependent c-Src activation." The Journal of biological chemistry.. 1999 Sep 17; 274(38):26803-9.
1999 Aug
Berk BC. "Redox signals that regulate the vascular response to injury." Thrombosis and haemostasis.. 1999 Aug; 82(2):810-7.
1999 Jul 23
Abe J, Berk BC. "Fyn and JAK2 mediate Ras activation by reactive oxygen species." The Journal of biological chemistry.. 1999 Jul 23; 274(30):21003-10.
1999 Jul 16
Traub O, Ishida T, Ishida M, Tupper JC, Berk BC. "Shear stress-mediated extracellular signal-regulated kinase activation is regulated by sodium in endothelial cells. Potential role for a voltage-dependent sodium channel." The Journal of biological chemistry.. 1999 Jul 16; 274(29):20144-50.
1999 Jul 16
Takahashi E, Abe J, Gallis B, Aebersold R, Spring DJ, Krebs EG, Berk BC. "p90(RSK) is a serum-stimulated Na+/H+ exchanger isoform-1 kinase. Regulatory phosphorylation of serine 703 of Na+/H+ exchanger isoform-1." The Journal of biological chemistry.. 1999 Jul 16; 274(29):20206-14.
1999 Jul 9
Peterson TE, Poppa V, Ueba H, Wu A, Yan C, Berk BC. "Opposing effects of reactive oxygen species and cholesterol on endothelial nitric oxide synthase and endothelial cell caveolae." Circulation research.. 1999 Jul 9; 85(1):29-37.
1999 Jun 25
Vatner SF, Berk BC, Hintze TH, Leinwand LA, Libby P, Marban E, Schwartz K, Strauss HC, Yazaki Y. "Eight years behind the masthead" Circulation research.. 1999 Jun 25; 84(12):1361-4.
1999 Jun
Delehanty JM, Ling FS, Berk BC. "If I had an acute coronary syndrome..." Lancet.. 1999 Jun; 353 Suppl 2:SII24-6.
1999 Mar
Ishida T, Ishida M, Suero J, Takahashi M, Berk BC. "Agonist-stimulated cytoskeletal reorganization and signal transduction at focal adhesions in vascular smooth muscle cells require c-Src." The Journal of clinical investigation.. 1999 Mar; 103(6):789-97.
1999 Jan 1
Yan C, Takahashi M, Okuda M, Lee JD, Berk BC. "Fluid shear stress stimulates big mitogen-activated protein kinase 1 (BMK1) activity in endothelial cells. Dependence on tyrosine kinases and intracellular calcium." The Journal of biological chemistry.. 1999 Jan 1; 274(1):143-50.
1999 Jan
Berk BC. "Angiotensin II signal transduction in vascular smooth muscle: pathways activated by specific tyrosine kinases." Journal of the American Society of Nephrology : JASN.. 1999 Jan; 10 Suppl 11:S62-8.
1999
Takeishi Y, Abe J, Lee JD, Kawakatsu H, Walsh RA, Berk BC. "Differential regulation of p90 ribosomal S6 kinase and big mitogen-activated protein kinase 1 by ischemia/reperfusion and oxidative stress in perfused guinea pig hearts." Circulation research.. 1999 85(12):1164-72.
1998 Oct 19
Kusuhara M, Takahashi E, Peterson TE, Abe J, Ishida M, Han J, Ulevitch R, Berk BC. "p38 Kinase is a negative regulator of angiotensin II signal transduction in vascular smooth muscle cells: effects on Na+/H+ exchange and ERK1/2." Circulation research.. 1998 Oct 19; 83(8):824-31.
1998 Oct 5
Melaragno MG, Wuthrich DA, Poppa V, Gill D, Lindner V, Berk BC, Corson MA. "Increased expression of Axl tyrosine kinase after vascular injury and regulation by G protein-coupled receptor agonists in rats." Circulation research.. 1998 Oct 5; 83(7):697-704.
1998 Aug
Poppa V, Miyashiro JK, Corson MA, Berk BC. "Endothelial NO synthase is increased in regenerating endothelium after denuding injury of the rat aorta." Arteriosclerosis, thrombosis, and vascular biology.. 1998 Aug; 18(8):1312-21.
1998 Jun 29
Schmitz U, Ishida T, Ishida M, Surapisitchat J, Hasham MI, Pelech S, Berk BC. "Angiotensin II stimulates p21-activated kinase in vascular smooth muscle cells: role in activation of JNK." Circulation research.. 1998 Jun 29; 82(12):1272-8.
1998 May
Traub O, Berk BC. "Laminar shear stress: mechanisms by which endothelial cells transduce an atheroprotective force." Arteriosclerosis, thrombosis, and vascular biology.. 1998 May; 18(5):677-85.
1998 Feb
Abe J, Berk BC. "Reactive oxygen species as mediators of signal transduction in cardiovascular disease." Trends in cardiovascular medicine. 1998 Feb; 8(2):59-64.
1998
Berk, B.C.; Canessa, M.; Vallega, G.; Alexander, R.W. "Agonist-mediated changes in intracellular pH: role in vascular smooth muscle cell function." J Cardiovasc Pharmacol. 1998; 12(Suppl 5): S104-14. Link
1998
Ishida M, Ishida T, Thomas SM, Berk BC. "Activation of extracellular signal-regulated kinases (ERK1/2) by angiotensin II is dependent on c-Src in vascular smooth muscle cells." Circulation research.. 1998 82(1):7-12.
1998
Takahashi E, Berk BC. "MAP kinases and vascular smooth muscle function." Acta physiologica Scandinavica. 1998 164(4):611-21.
1997 Nov 18
Nunes GL, Robinson K, Kalynych A, King SB, Sgoutas DS, Berk BC. "Vitamins C and E inhibit O2- production in the pig coronary artery." Circulation.. 1997 Nov 18; 96(10):3593-601.
1997 Oct
Schmitz U, Ishida M, Berk BC. "Angiotensin II stimulates tyrosine phosphorylation of phospholipase C-gamma-associated proteins. Characterization of a c-Src-dependent 97-kD protein in vascular smooth muscle cells." Circulation research.. 1997 Oct; 81(4):550-7.
1997 Sep
Miyashiro JK, Poppa V, Berk BC. "Flow-induced vascular remodeling in the rat carotid artery diminishes with age." Circulation research.. 1997 Sep; 81(3):311-9.
1997 Sep
Mondy JS, Lindner V, Miyashiro JK, Berk BC, Dean RH, Geary RL. "Platelet-derived growth factor ligand and receptor expression in response to altered blood flow in vivo." Circulation research.. 1997 Sep; 81(3):320-7.
1997 Sep
Schmitz U, Berk BC. "Angiotensin II signal transduction: Stimulation of multiple mitogen-activated protein kinase pathways." Trends in endocrinology and metabolism: TEM. 1997 Sep; 8(7):261-6.
1997 Aug 15
Abe J, Takahashi M, Ishida M, Lee JD, Berk BC. "c-Src is required for oxidative stress-mediated activation of big mitogen-activated protein kinase 1." The Journal of biological chemistry.. 1997 Aug 15; 272(33):20389-94.
1997 Aug
Takahashi E, Abe J, Berk BC. "Angiotensin II stimulates p90rsk in vascular smooth muscle cells. A potential Na(+)-H+ exchanger kinase." Circulation research.. 1997 Aug; 81(2):268-73.
1997 Jun
Phan VN, Kusuhara M, Lucchesi PA, Berk BC. "A 90-kD Na(+)-H+ exchanger kinase has increased activity in spontaneously hypertensive rat vascular smooth muscle cells." Hypertension.. 1997 Jun; 29(6):1265-72.
1997 Jun
Ishida M, Berk BC. "Angiotensin II signal transduction in vascular smooth muscle cells: role of tyrosine kinases." The Keio journal of medicine. 1997 Jun; 46(2):61-8.
1997 May
Berk BC, Corson MA. "Angiotensin II signal transduction in vascular smooth muscle: role of tyrosine kinases." Circulation research.. 1997 May; 80(5):607-16.
1997 Apr 15
Wiesner TF, Berk BC, Nerem RM. "A mathematical model of the cytosolic-free calcium response in endothelial cells to fluid shear stress." Proceedings of the National Academy of Sciences of the United States of America.. 1997 Apr 15; 94(8):3726-31.
1997 Apr 15
Ishida T, Takahashi M, Corson MA, Berk BC. "Fluid shear stress-mediated signal transduction: how do endothelial cells transduce mechanical force into biological responses?" Annals of the New York Academy of Sciences.. 1997 Apr 15; 811:12-23; discussion 23-4.
1997 Mar 7
Liao DF, Monia B, Dean N, Berk BC. "Protein kinase C-zeta mediates angiotensin II activation of ERK1/2 in vascular smooth muscle cells." The Journal of biological chemistry.. 1997 Mar 7; 272(10):6146-50.
1997 Jan
Kusuhara M, Chait A, Cader A, Berk BC. "Oxidized LDL stimulates mitogen-activated protein kinases in smooth muscle cells and macrophages." Arteriosclerosis, thrombosis, and vascular biology.. 1997 Jan; 17(1):141-8.
1997
Traub O, Monia BP, Dean NM, Berk BC. "PKC-epsilon is required for mechano-sensitive activation of ERK1/2 in endothelial cells." The Journal of biological chemistry.. 1997 272(50):31251-7.
1997
Takahashi M, Ishida T, Traub O, Corson MA, Berk BC. "Mechanotransduction in endothelial cells: temporal signaling events in response to shear stress." Journal of vascular research. 1997 34(3):212-9.
1996 Nov
Corson MA, James NL, Latta SE, Nerem RM, Berk BC, Harrison DG. "Phosphorylation of endothelial nitric oxide synthase in response to fluid shear stress." Circulation research.. 1996 Nov; 79(5):984-91.
1996 Nov
Liao DF, Duff JL, Daum G, Pelech SL, Berk BC. "Angiotensin II stimulates MAP kinase kinase kinase activity in vascular smooth muscle cells, Role of Raf." Circulation research.. 1996 Nov; 79(5):1007-14.
1996 Aug
Ishida T, Peterson TE, Kovach NL, Berk BC. "MAP kinase activation by flow in endothelial cells. Role of beta 1 integrins and tyrosine kinases." Circulation research.. 1996 Aug; 79(2):310-6.
1996 Jul 12
Abe J, Kusuhara M, Ulevitch RJ, Berk BC, Lee JD. "Big mitogen-activated protein kinase 1 (BMK1) is a redox-sensitive kinase." The Journal of biological chemistry.. 1996 Jul 12; 271(28):16586-90.
1996 Jul
Vatner SF, Berk BC, Leinwand LA, Libby P, Schwartz K, Strauss HC. "A second term for the editors. Status and goals for the review process." Circulation research.. 1996 Jul; 79(1):1-3.
1996 Jun
Lucchesi PA, Bell JM, Willis LS, Byron KL, Corson MA, Berk BC. "Ca(2+)-dependent mitogen-activated protein kinase activation in spontaneously hypertensive rat vascular smooth muscle defines a hypertensive signal transduction phenotype." Circulation research.. 1996 Jun; 78(6):962-70.
1996 May
Wiesner TF, Berk BC, Nerem RM. "A mathematical model of cytosolic calcium dynamics in human umbilical vein endothelial cells." The American journal of physiology. 1996 May; 270(5 Pt 1):C1556-69.
1996
Takahashi M, Berk BC. "Mitogen-activated protein kinase (ERK1/2) activation by shear stress and adhesion in endothelial cells. Essential role for a herbimycin-sensitive kinase." The Journal of clinical investigation.. 1996 98(11):2623-31.
1996
Helmlinger G, Berk BC, Nerem RM. "Pulsatile and steady flow-induced calcium oscillations in single cultured endothelial cells." Journal of vascular research. 1996 33(5):360-9.
1995 Nov
Tseng H, Peterson TE, Berk BC. "Fluid shear stress stimulates mitogen-activated protein kinase in endothelial cells." Circulation research.. 1995 Nov; 77(5):869-78.
1995 Oct
Duff JL, Marrero MB, Paxton WG, Schieffer B, Bernstein KE, Berk BC. "Angiotensin II signal transduction and the mitogen-activated protein kinase pathway." Cardiovascular research. 1995 Oct; 30(4):511-7.
1995 Oct
Marrero MB, Schieffer B, Paxton WG, Duff JL, Berk BC, Bernstein KE. "The role of tyrosine phosphorylation in angiotensin II-mediated intracellular signalling." Cardiovascular research. 1995 Oct; 30(4):530-6.
1995 Aug
Helmlinger G, Berk BC, Nerem RM. "Calcium responses of endothelial cell monolayers subjected to pulsatile and steady laminar flow differ." The American journal of physiology. 1995 Aug; 269(2 Pt 1):C367-75.
1995 Jul
Baas AS, Berk BC. "Differential activation of mitogen-activated protein kinases by H2O2 and O2- in vascular smooth muscle cells." Circulation research.. 1995 Jul; 77(1):29-36.
1995 May 18
Marrero MB, Schieffer B, Paxton WG, Heerdt L, Berk BC, Delafontaine P, Bernstein KE. "Direct stimulation of Jak/STAT pathway by the angiotensin II AT1 receptor." Nature. 1995 May 18; 375(6528):247-50.
1995 Mar 31
Duff JL, Monia BP, Berk BC. "Mitogen-activated protein (MAP) kinase is regulated by the MAP kinase phosphatase (MKP-1) in vascular smooth muscle cells. Effect of actinomycin D and antisense oligonucleotides." The Journal of biological chemistry.. 1995 Mar 31; 270(13):7161-6.
1995 Mar
Fishel RS, Eisenberg S, Shai SY, Redden RA, Bernstein KE, Berk BC. "Glucocorticoids induce angiotensin-converting enzyme expression in vascular smooth muscle." Hypertension.. 1995 Mar; 25(3):343-9.
1995 Feb
Lucchesi PA, Berk BC. "Regulation of sodium-hydrogen exchange in vascular smooth muscle." Cardiovascular research. 1995 Feb; 29(2):172-7.
1995 Jan
Nunes GL, Sgoutas DS, Redden RA, Sigman SR, Gravanis MB, King SB, Berk BC. "Combination of vitamins C and E alters the response to coronary balloon injury in the pig." Arteriosclerosis, thrombosis, and vascular biology.. 1995 Jan; 15(1):156-65.
1995 Jan
Fishel RS, Thourani V, Eisenberg SJ, Shai SY, Corson MA, Nabel EG, Bernstein KE, Berk BC. "Fibroblast growth factor stimulates angiotensin converting enzyme expression in vascular smooth muscle cells. Possible mediator of the response to vascular injury." The Journal of clinical investigation.. 1995 Jan; 95(1):377-87.
1995
Eisenberg, S.; Berk, B.C. "The endothelial cell." Resident and Staff Physician. 1995; 41: 13-23. Link
1995
Helmlinger, G.; Berk, B.C.; Nerem, R.M. "Flow-induced calcium responses in endothelial cells are synergistically modulated by serum." J Cellular Engineering. 1995; 1: 13-20. Link
1995
Duff JL, Berk BC. "Angiotensin II-mediated signal transduction events in vascular smooth muscle cells: kinases and phosphatases." Blood pressure. Supplement. 1995 2:55-60.
1995
Ishida M, Marrero MB, Schieffer B, Ishida T, Bernstein KE, Berk BC. "Angiotensin II activates pp60c-src in vascular smooth muscle cells." Circulation research.. 1995 77(6):1053-9.
1995
Berk BC, Harris K. "Restenosis after percutaneous transluminal coronary angioplasty: new therapeutic insights from pathogenic mechanisms." Advances in internal medicine. 1995 40:445-501.
1995
Berk BC, Corson MA, Peterson TE, Tseng H. "Protein kinases as mediators of fluid shear stress stimulated signal transduction in endothelial cells: a hypothesis for calcium-dependent and calcium-independent events activated by flow." Journal of biomechanics. 1995 28(12):1439-50.
1994 Apr 15
Paxton WG, Marrero MB, Klein JD, Delafontaine P, Berk BC, Bernstein KE. "The angiotensin II AT1 receptor is tyrosine and serine phosphorylated and can serve as a substrate for the src family of tyrosine kinases." Biochemical and biophysical research communications.. 1994 Apr 15; 200(1):260-7.
1994 Apr 8
Marrero MB, Paxton WG, Duff JL, Berk BC, Bernstein KE. "Angiotensin II stimulates tyrosine phosphorylation of phospholipase C-gamma 1 in vascular smooth muscle cells." The Journal of biological chemistry.. 1994 Apr 8; 269(14):10935-9.
1994
Lucchesi PA, DeRoux N, Berk BC. "Na(+)-H+ exchanger expression in vascular smooth muscle of spontaneously hypertensive and Wistar-Kyoto rats." Hypertension.. 1994 24(6):734-8.
1993 Nov
Bernstein KE, Berk BC. "The biology of angiotensin II receptors." American journal of kidney diseases : the official journal of the National Kidney Foundation.. 1993 Nov; 22(5):745-54.
1993 Aug
Schneider JE, Berk BC, Gravanis MB, Santoian EC, Cipolla GD, Tarazona N, Lassegue B, King SB. "Probucol decreases neointimal formation in a swine model of coronary artery balloon injury. A possible role for antioxidants in restenosis." Circulation.. 1993 Aug; 88(2):628-37.
1993 Aug
Mitsuka M, Nagae M, Berk BC. "Na(+)-H+ exchange inhibitors decrease neointimal formation after rat carotid injury. Effects on smooth muscle cell migration and proliferation." Circulation research.. 1993 Aug; 73(2):269-75.
1993 Jul
Mitsumata M, Fishel RS, Nerem RM, Alexander RW, Berk BC. "Fluid shear stress stimulates platelet-derived growth factor expression in endothelial cells." The American journal of physiology. 1993 Jul; 265(1 Pt 2):H3-8.
1993 May
Rao GN, Sardet C, Pouysségur J, Berk BC. "Phosphorylation of Na(+)-H+ antiporter is not stimulated by phorbol ester and acidification in granulocytic HL-60 cells." The American journal of physiology. 1993 May; 264(5 Pt 1):C1278-84.
1993 Mar 11
Rao GN, Lasségue B, Griendling KK, Alexander RW, Berk BC. "Hydrogen peroxide-induced c-fos expression is mediated by arachidonic acid release: role of protein kinase C." Nucleic acids research.. 1993 Mar 11; 21(5):1259-63.
1993 Feb
Berk BC, Rao GN. "Angiotensin II-induced vascular smooth muscle cell hypertrophy: PDGF A-chain mediates the increase in cell size." Journal of cellular physiology. 1993 Feb; 154(2):368-80.
1993
Duff JL, Marrero MB, Paxton WG, Charles CH, Lau LF, Bernstein KE, Berk BC. "Angiotensin II induces 3CH134, a protein-tyrosine phosphatase, in vascular smooth muscle cells." The Journal of biological chemistry.. 1993 268(35):26037-40.
1993
Berk, B.C. "Endothelial dysfunction in atherosclerosis." Choice in Cardiology. 1993; 21: 1259-1263. Link
1993
Corson MA, Berk BC. "Growth factors and the vessel wall." Heart disease and stroke : a journal for primary care physicians. 1993 2(2):166-70.
1992 Oct 15
Duff JL, Berk BC, Corson MA. "Angiotensin II stimulates the pp44 and pp42 mitogen-activated protein kinases in cultured rat aortic smooth muscle cells." Biochemical and biophysical research communications.. 1992 Oct 15; 188(1):257-64.
1992 Aug
Krug LM, Berk BC. "Na+, K(+)-adenosine triphosphatase regulation in hypertrophied vascular smooth muscle cells." Hypertension.. 1992 Aug; 20(2):144-50.
1992 Jun
Shai SY, Fishel RS, Martin BM, Berk BC, Bernstein KE. "Bovine angiotensin converting enzyme cDNA cloning and regulation. Increased expression during endothelial cell growth arrest." Circulation research.. 1992 Jun; 70(6):1274-81.
1992 Jun
Geiger RV, Berk BC, Alexander RW, Nerem RM. "Flow-induced calcium transients in single endothelial cells: spatial and temporal analysis." The American journal of physiology. 1992 Jun; 262(6 Pt 1):C1411-7.
1992 May
Rao GN, Sardet C, Pouysségur J, Berk BC. "Na+/H+ antiporter gene expression increases during retinoic acid-induced granulocytic differentiation of HL60 cells." Journal of cellular physiology. 1992 May; 151(2):361-6.
1992 Apr 25
Tseng H, Berk BC. "The Na/K/2Cl cotransporter is increased in hypertrophied vascular smooth muscle cells." The Journal of biological chemistry.. 1992 Apr 25; 267(12):8161-7.
1992 Mar
Rao GN, Berk BC. "Active oxygen species stimulate vascular smooth muscle cell growth and proto-oncogene expression." Circulation research.. 1992 Mar; 70(3):593-9.
1992 Feb
Corson MA, Alexander RW, Berk BC. "5-HT2 receptor mRNA is overexpressed in cultured rat aortic smooth muscle cells relative to normal aorta." The American journal of physiology. 1992 Feb; 262(2 Pt 1):C309-15.
1992 Feb
Taubman MB, Rollins BJ, Poon M, Marmur J, Green RS, Berk BC, Nadal-Ginard B. "JE mRNA accumulates rapidly in aortic injury and in platelet-derived growth factor-stimulated vascular smooth muscle cells." Circulation research.. 1992 Feb; 70(2):314-25.
1992
Berk, B.C.; Corson, M.A. "Autocrine and paracrine growth mechanisms in vascular smooth muscle." Current Opinions in Cardiology. 1992; 7: 739-744. Link
1992
Rothman A, Kulik TJ, Taubman MB, Berk BC, Smith CW, Nadal-Ginard B. "Development and characterization of a cloned rat pulmonary arterial smooth muscle cell line that maintains differentiated properties through multiple subcultures." Circulation.. 1992 86(6):1977-86.
1991 Jul 25
Rao GN, de Roux N, Sardet C, Pouysségur J, Berk BC. "Na+/H+ antiporter gene expression during monocytic differentiation of HL60 cells." The Journal of biological chemistry.. 1991 Jul 25; 266(21):13485-8.
1991 Jul
Berk BC. "The microcirculation in coronary ischemia. Are native anticoagulant mechanisms a path to new therapies?" Circulation.. 1991 Jul; 84(1):439-41.
1991 May 5
Rao GN, Corson MA, Berk BC. "Uric acid stimulates vascular smooth muscle cell proliferation by increasing platelet-derived growth factor A-chain expression." The Journal of biological chemistry.. 1991 May 5; 266(13):8604-8.
1991 May
Berk BC, Gordon JB, Alexander RW. "Pharmacologic roles of heparin and glucocorticoids to prevent restenosis after coronary angioplasty." Journal of the American College of Cardiology.. 1991 May; 17(6 Suppl B):111B-117B.
1991 Apr
Liu MW, Berk BC. "Restenosis following coronary balloon angioplasty Role of smooth muscle cell proliferation." Trends in cardiovascular medicine. 1991 Apr; 1(3):107-11.
1991 Mar 15
Berk BC, Taubman MB, Griendling KK, Cragoe EJ, Fenton JW, Brock TA. "Thrombin-stimulated events in cultured vascular smooth-muscle cells." The Biochemical journal. 1991 Mar 15; 274 ( Pt 3):799-805.
1991 Mar
Mitsuka M, Berk BC. "Long-term regulation of Na(+)-H+ exchange in vascular smooth muscle cells: role of protein kinase C." The American journal of physiology. 1991 Mar; 260(3 Pt 1):C562-9.
1991
Liu M.W.; Berk, B.C. "Restenosis following coronary balloon angioplasty: Role of smooth muscle cell proliferation." Trends in Cardiovascular Medicine. 1991; 1: 107-111. Link
1990 Nov 15
Rao GN, Sardet C, Pouysségur J, Berk BC. "Differential regulation of Na+/H+ antiporter gene expression in vascular smooth muscle cells by hypertrophic and hyperplastic stimuli." The Journal of biological chemistry.. 1990 Nov 15; 265(32):19393-6.
1990 Nov 15
Berk BC, Elder E, Mitsuka M. "Hypertrophy and hyperplasia cause differing effects on vascular smooth muscle cell Na+/H+ exchange and intracellular pH." The Journal of biological chemistry.. 1990 Nov 15; 265(32):19632-7.
1990 Oct 5
Berk BC, Taubman MB, Cragoe EJ, Fenton JW, Griendling KK. "Thrombin signal transduction mechanisms in rat vascular smooth muscle cells. Calcium and protein kinase C-dependent and -independent pathways." The Journal of biological chemistry.. 1990 Oct 5; 265(28):17334-40.
1990 Jan 15
Berk BC, Weintraub WS, Alexander RW. "Elevation of C-reactive protein in "active" coronary artery disease." The American journal of cardiology.. 1990 Jan 15; 65(3):168-72.
1989 Aug
Griendling KK, Tsuda T, Berk BC, Alexander RW. "Angiotensin II stimulation of vascular smooth muscle cells. Secondary signalling mechanisms." American journal of hypertension. 1989 Aug; 2(8):659-65.
1989 Apr
Berk BC, Vekshtein V, Gordon HM, Tsuda T. "Angiotensin II-stimulated protein synthesis in cultured vascular smooth muscle cells." Hypertension.. 1989 Apr; 13(4):305-14.
1989 Mar
Berk BC, Vallega G, Muslin AJ, Gordon HM, Canessa M, Alexander RW. "Spontaneously hypertensive rat vascular smooth muscle cells in culture exhibit increased growth and Na+/H+ exchange." The Journal of clinical investigation.. 1989 Mar; 83(3):822-9.
1989 Jan 15
Berk BC, Alexander RW. "Vasoactive effects of growth factors." Biochemical pharmacology. 1989 Jan 15; 38(2):219-25.
1989 Jan 5
Taubman MB, Berk BC, Izumo S, Tsuda T, Alexander RW, Nadal-Ginard B. "Angiotensin II induces c-fos mRNA in aortic smooth muscle. Role of Ca2+ mobilization and protein kinase C activation." The Journal of biological chemistry.. 1989 Jan 5; 264(1):526-30.
1989
Griendling KK, Tsuda T, Berk BC, Alexander RW. "Angiotensin II stimulation of vascular smooth muscle." Journal of cardiovascular pharmacology. 1989 14 Suppl 6:S27-33.
1988 Aug 5
Griendling KK, Berk BC, Alexander RW. "Evidence that Na+/H+ exchange regulates angiotensin II-stimulated diacylglycerol accumulation in vascular smooth muscle cells." The Journal of biological chemistry.. 1988 Aug 5; 263(22):10620-4.
1988 Jun
Vallega GA, Canessa ML, Berk BC, Brock TA, Alexander RW. "Vascular smooth muscle Na+-H+ exchanger kinetics and its activation by angiotensin II." The American journal of physiology. 1988 Jun; 254(6 Pt 1):C751-8.
1988 Mar
Nabel EG, Berk BC, Brock TA, Smith TW. "Na+-Ca2+ exchange in cultured vascular smooth muscle cells." Circulation research.. 1988 Mar; 62(3):486-93.
1988 Feb
Griendling KK, Berk BC, Socorro L, Tsuda T, Delafontaine P, Alexander RW. "Secondary signalling mechanisms in angiotensin II-stimulated vascular smooth muscle cells." Clinical and experimental pharmacology & physiology. 1988 Feb; 15(2):105-12.
1988
Berk BC, Vallega G, Griendling KK, Gordon JB, Cragoe EJ, Canessa M, Alexander RW. "Effects of glucocorticoids on Na+/H+ exchange and growth in cultured vascular smooth muscle cells." Journal of cellular physiology. 1988 137(3):391-401.
1988
Berk BC, Canessa M, Vallega G, Alexander RW. "Agonist-mediated changes in intracellular pH: role in vascular smooth muscle cell function." Journal of cardiovascular pharmacology. 1988 12 Suppl 5:S104-14.
1987 Sep 23
Danthuluri NR, Berk BC, Brock TA, Cragoe EJ, Deth RC. "Protein kinase C-mediated intracellular alkalinization in rat and rabbit aortic smooth muscle cells." European journal of pharmacology. 1987 Sep 23; 141(3):503-6.
1987 Jun
Griendling KK, Berk BC, Ganz P, Gimbrone MA, Alexander RW. "Angiotensin II stimulation of vascular smooth muscle phosphoinositide metabolism. State of the art lecture." Hypertension.. 1987 Jun; 9(6 Pt 2):III181-5.
1987 Apr 15
Berk BC, Aronow MS, Brock TA, Cragoe E, Gimbrone MA, Alexander RW. "Angiotensin II-stimulated Na+/H+ exchange in cultured vascular smooth muscle cells. Evidence for protein kinase C-dependent and -independent pathways." The Journal of biological chemistry.. 1987 Apr 15; 262(11):5057-64.
1987 Apr 15
Berk BC, Brock TA, Gimbrone MA, Alexander RW. "Early agonist-mediated ionic events in cultured vascular smooth muscle cells. Calcium mobilization is associated with intracellular acidification." The Journal of biological chemistry.. 1987 Apr 15; 262(11):5065-72.
1986 Apr 4
Berk BC, Alexander RW, Brock TA, Gimbrone MA, Webb RC. "Vasoconstriction: a new activity for platelet-derived growth factor." Science (New York, N.Y.). 1986 Apr 4; 232(4746):87-90.
1985 Mar
Berk BC, Brock TA, Webb RC, Taubman MB, Atkinson WJ, Gimbrone MA, Alexander RW. "Epidermal growth factor, a vascular smooth muscle mitogen, induces rat aortic contraction." The Journal of clinical investigation.. 1985 Mar; 75(3):1083-6.
1981 Nov 25
Berk BC, Hinkle PM. "Purification of a stimulator of microtubule assembly from bovine thyroid." The Journal of biological chemistry.. 1981 Nov 25; 256(22):11859-65.
1980 Apr 10
Berk BC, Hinkle PM. "Thyroid and brain microtubules: a comparison." The Journal of biological chemistry.. 1980 Apr 10; 255(7):3186-93.