Edward G. Freedman, Ph.D.

Edward G. Freedman, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 603
Rochester, NY 14642

Office: (585) 273-1892

Lab Information

Visit Lab Website »


Research Bio

Effects of mild traumatic brain injury (sports-related concussion) on eye-head-hand coordination.



Sports-related concussions (mild traumatic brain injuries or mTBI) are estimated to occur between 1.6 and 3.8 million times annually in the United States. The dangers of repeated injuries can be severe, particularly if additional impacts occur before full recovery. Prevention, identification, treatment, rehabilitation, and determination of recovery time-points are largely inadequate due to the paucity of parametric factors that can be easily and reliably measured both in the field and in the clinic. The overarching goal of the proposed study is to identify behavioral markers of mTBI that will ultimately help protect athletes from the dangers of premature return to full activity by tracking and facilitating recovery after injury. To accomplish this, a battery of visual-spatial tasks has been designed that require coordination of the eyes, head and hand and address sensorimotor plasticity, spatial working memory, and visuo-spatial orientation. These particular tasks have been selected because they permit a focused assessment of a variety of critical brain functions. Functions that when disrupted by mTBI can result in disorientation, dysmetria, and dyscoordination and are often symptoms of mild TBI in human subjects as well as in animal models of TBI. Careful analysis of movement kinematics and coordination during eye-head-hand orienting movements, movements to remembered target locations, visual guidance and control of hand trajectories, and tasks that require adaptive plasticity of coordination will yield parameters that pinpoint effects of mTBI, its progression and recovery to an extent that existing clinical exams and tests do not allow.

For more information visit the Lab Website: http://www.urmc.rochester.edu/labs/freedman-lab/

Awards & Honors (Local)

NSF CAREER Award 2002
Alfred P. Sloan Research Fellow. 2001
Donald B. Lindsley Prize in Behavioral Neuroscience, (The Grass Foundation/The Society for Neuroscience). 1997
Saul Winegrad, M.D. Award for outstanding dissertation (Neuroscience) - Biomedical Graduate Studies, | Univ. of Pennsylvania. 1997
Louis B. Flexner Award for outstanding dissertation research - Institute of Neurological Sciences, | Univ. of Pennsylvania 1996

Recent Journal Articles

Showing the 5 most recent journal articles. 31 available »

2014 Jan
Walton MM, Freedman EG. "Activity of long-lead burst neurons in pontine reticular formation during head-unrestrained gaze shifts." Journal of neurophysiology. 2014 Jan; 111(2):300-12. Epub 2013 Oct 30.
2012
Walton, MMG; Freedman, EG. "Activity of long lead burst neurons in pontine reticular formation during head-unrestrained gaze shifts." JNeurophysiol. 2012; .
2011 Oct
Walton MM, Freedman EG. "Gaze shift duration, independent of amplitude, influences the number of spikes in the burst for medium-lead burst neurons in pontine reticular formation." Experimental brain research. 2011 Oct; 214(2):225-39. Epub 2011 Aug 14.
2010 Oct 20
Quessy S, Quinet J, Freedman EG. "The locus of motor activity in the superior colliculus of the rhesus monkey is unaltered during saccadic adaptation." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2010 Oct 20; 30(42):14235-44.
2010
Quessy, S., Quinet, J., Freedman, E. G. "The locus of motor activity in the superior colliculus of the rhesus monkey is unaltered during saccadic adaptation". J. Neuroscience. 2010; : 14235-44.

Current Appointments

Associate Professor - Department of Neurobiology and Anatomy (SMD) - Primary
Associate Professor - Center for Visual Science A&S (RC)

Education

PhD | Neuroscience | Univ of Pennsylvania1996
MS | Neurobiology | Cornell University1992
BS | Biology | Brown University1986

Post-Doctoral Training & Residency

Post-doctoral Fellow, Univ. of Washington, Seattle WA 1999
Post-doctoral Fellow, Univ. of Pennsylvania, Philadelphia PA. 1997