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Bruce M. Fenton, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 704
Rochester, NY 14642

Journal Articles

Showing all 63 journal articles available.

2007 Oct 15
Fenton BM, Paoni SF. "The addition of AG-013736 to fractionated radiation improves tumor response without functionally normalizing the tumor vasculature." Cancer research.. 2007 Oct 15; 67(20):9921-8.
2007 Aug 15
Wang W, Yang S, Su Y, Xiao Z, Wang C, Li X, Lin L, Fenton BM, Paoni SF, Ding I, Keng P, Okunieff P, Zhang L. "Enhanced antitumor effect of combined triptolide and ionizing radiation." Clinical cancer research : an official journal of the American Association for Cancer Research.. 2007 Aug 15; 13(16):4891-9.
2007
Okunieff P, Sun J, Fenton B, Liu W, Ding I. "Intratumoral VEGF and FGF1 administration alters tumor growth, vascular density, oxygenation, and expression of MCP-1 and interleukins." Advances in experimental medicine and biology. 2007 599:109-16.
2006 Jun
Winey BA, Misic V, Liao L, Parker K, Fenton BM, Yu Y. "In vivo cancer diagnosis with optical spectroscopy and acoustically induced blood stasis using a murine MCa35 model." Medical physics.. 2006 Jun; 33(6):1623-33.
2006
Conover,D.L.; Ning,R.; Paoni,S.; Wilson,I.; Lu,X.; Zhang,Y.; Fenton,B.;. "Cone beam computed tomography angiogenesis imaging: Preliminary studies". Proc.of SPIE. 2006; 6143: 61433G1-6.
2005
Winey,B.A.; Misic,V.; Fenton,B.; Paoni,S.; Liao,L.; Okunieff,P.; Liu,H..; Parker,K.J.; Yu,Y;. "In vivo optical spectroscopy of acoustically induced blood stasis". Proceedings of the 2005 IEEE. 2005; .
2005
Fenton BM, Paoni SF, Grimwood B, Ding I. "Varied response of spontaneous tumors to antiangiogenic agents." Advances in experimental medicine and biology. 2005 566:59-65.
2005
Okunieff P, Fenton B, Chen Y. "Past, present, and future of oxygen in cancer research." Advances in experimental medicine and biology. 2005 566:213-22.
2005
Misic V, Winey B, Liu H, Liao L, Okunieff P, Parker K, Fenton B, Yu Y. "Tumor Detection in vivo with Optical Spectroscopy." Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society.. 2005 5:4708-11.
2004 Aug 15
Fenton BM, Paoni SF, Ding I. "Pathophysiological effects of vascular endothelial growth factor receptor-2-blocking antibody plus fractionated radiotherapy on murine mammary tumors." Cancer research.. 2004 Aug 15; 64(16):5712-9.
2004 Aug
Fenton BM, Paoni SF, Ding I. "Effect of VEGF receptor-2 antibody on vascular function and oxygenation in spontaneous and transplanted tumors." Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 2004 Aug; 72(2):221-30.
2004 May
Williams JP, Hernady E, Johnston CJ, Reed CM, Fenton B, Okunieff P, Finkelstein JN. "Effect of administration of lovastatin on the development of late pulmonary effects after whole-lung irradiation in a murine model." Radiation research.. 2004 May; 161(5):560-7.
2004 Jan 26
Fenton BM, Paoni SF, Liu W, Cheng SY, Hu B, Ding I. "Overexpression of VEGF121, but not VEGF165 or FGF-1, improves oxygenation in MCF-7 breast tumours." British journal of cancer.. 2004 Jan 26; 90(2):430-5.
2003 Nov 15
Fenton BM, Paoni SF, Grimwood BG, Ding I. "Disparate effects of endostatin on tumor vascular perfusion and hypoxia in two murine mammary carcinomas." International journal of radiation oncology, biology, physics.. 2003 Nov 15; 57(4):1038-46.
2003 Aug 1
Guo P, Fang Q, Tao HQ, Schafer CA, Fenton BM, Ding I, Hu B, Cheng SY. "Overexpression of vascular endothelial growth factor by MCF-7 breast cancer cells promotes estrogen-independent tumor growth in vivo." Cancer research.. 2003 Aug 1; 63(15):4684-91.
2003 Aug
Liu W, Chen Y, Wang W, Keng P, Finkelstein J, Hu D, Liang L, Guo M, Fenton B, Okunieff P, Ding I. "Combination of radiation and celebrex (celecoxib) reduce mammary and lung tumor growth." American journal of clinical oncology.. 2003 Aug; 26(4):S103-9.
2003 May 6
Gerber SA, Moran JP, Frelinger JG, Frelinger JA, Fenton BM, Lord EM. "Mechanism of IL-12 mediated alterations in tumour blood vessel morphology: analysis using whole-tissue mounts." British journal of cancer.. 2003 May 6; 88(9):1453-61.
2003
Fenton BM, Paoni SF, Beauchamp BK, Tran B, Liang L, Grimwood B, Ding I. "Evaluation of microregional variations in tumor hypoxia following the administration of endostatin." Advances in experimental medicine and biology. 2003 510:19-24.
2003
Fenton BM, Paoni SF. "Oxygenation and vascular perfusion in spontaneous and transplanted tumor models." Advances in experimental medicine and biology. 2003 530:165-76.
2003
Okunieff P, Fenton BM, Zhang L, Kern FG, Wu T, Greg JR, Ding I. "Fibroblast growth factors (FGFS) increase breast tumor growth rate, metastases, blood flow, and oxygenation without significant change in vascular density." Advances in experimental medicine and biology. 2003 530:593-601.
2003
Ding I, Liu W, Sun J, Paoni SF, Hernady E, Fenton BM, Okunieff P. "FGF1 and VEGF mediated angiogenesis in KHT tumor-bearing mice." Advances in experimental medicine and biology. 2003 530:603-9.
2003
Ding I, Okunieff P, Salnikow K, Liu W, Fenton B. "A new intrinsic hypoxia marker in esophageal cancer." Advances in experimental medicine and biology. 2003 540:227-33.
2002 Jun 5
Fenton BM, Paoni SF, Beauchamp BK, Ding I. "Zonal image analysis of tumour vascular perfusion, hypoxia, and necrosis." British journal of cancer.. 2002 Jun 5; 86(11):1831-6.
2002 May
Ding I, Liu W, Sun J, Fenton B, Okunieff P. "Comparison and modulation of angiogenic responses by FGFs, VEGF and SCF in murine and human fibrosarcomas." Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 2002 May; 132(1):17-25.
2001 Oct
Fenton BM, Beauchamp BK, Paoni SF, Okunieff P, Ding I. "Characterization of the effects of antiangiogenic agents on tumor pathophysiology." American journal of clinical oncology.. 2001 Oct; 24(5):453-7.
2001 Oct
Okunieff P, Li M, Liu W, Sun J, Fenton B, Zhang L, Ding I. "Keratinocyte growth factors radioprotect bowel and bone marrow but not KHT sarcoma." American journal of clinical oncology.. 2001 Oct; 24(5):491-5.
2001 Sep 1
Fenton BM, Lord EM, Paoni SF. "Intravascular HBO(2) saturations, perfusion and hypoxia in spontaneous and transplanted tumor models." International journal of cancer. Journal international du cancer.. 2001 Sep 1; 93(5):693-8.
2001 Mar 1
Fenton BM. "Influence of hydralazine administration on oxygenation in spontaneous and transplanted tumor models." International journal of radiation oncology, biology, physics.. 2001 Mar 1; 49(3):799-808.
2001 Feb
Fenton BM, Lord EM, Paoni SF. "Effects of radiation on tumor intravascular oxygenation, vascular configuration, development of hypoxia, and clonogenic survival." Radiation research.. 2001 Feb; 155(2):360-8.
2001 Jan 15
Ding I, Sun JZ, Fenton B, Liu WM, Kimsely P, Okunieff P, Min W. "Intratumoral administration of endostatin plasmid inhibits vascular growth and perfusion in MCa-4 murine mammary carcinomas." Cancer research.. 2001 Jan 15; 61(2):526-31.
2001
Conover,D.L.; Fenton,B.M.; Foster,T.H.; Hull,E.L.;. "An evaluation of near infrared spectroscopy and cryospectrophotometry estimates of haemoglobin oxygen saturation in a rodent mammary tumour model". Phys Med Biol. 2001; 45(9): 2685-2700.
2000 Jan
Fenton BM, Lord EM, Paoni SF. "Enhancement of tumor perfusion and oxygenation by carbogen and nicotinamide during single- and multifraction irradiation." Radiation research.. 2000 Jan; 153(1):75-83.
1999 Feb
Fenton BM, Paoni SF, Lee J, Koch CJ, Lord EM. "Quantification of tumour vasculature and hypoxia by immunohistochemical staining and HbO2 saturation measurements." British journal of cancer.. 1999 Feb; 79(3-4):464-71.
1999
Lee,J.; Moran,J.P.; Fenton,B.M.; Koch,C.J.; Frelinger,J.G.; Keng,P.C.; Lord,E.M.;. "Alteration of tumor response to radiation by interleukin-2 gene transfer". Br.J.Cancer. 1999; 82(4): 937-944.
1999
Schell MC, Rosenzweig DP, Weaver KA, Fenton BM, Rubin P. "Characterization of the dose perturbation by stents as a function of X-ray beam energy." Cardiovascular radiation medicine. 1999 1(2):154-9.
1998 Apr 1
Lee J, Fenton BM, Koch CJ, Frelinger JG, Lord EM. "Interleukin 2 expression by tumor cells alters both the immune response and the tumor microenvironment." Cancer research.. 1998 Apr 1; 58(7):1478-85.
1998
Fenton BM, Paoni SF, Koch CJ, Lord EM. "Effect of local irradiation on tumor oxygenation, perfused vessel density, and development of hypoxia." Advances in experimental medicine and biology. 1998 454:619-28.
1997 Aug
Fenton BM. "Effects of carbogen plus fractionated irradiation on KHT tumor oxygenation." Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 1997 Aug; 44(2):183-90.
1997 Jan
Kiani MF, Fenton BM, Sporn LA, Siemann DW. "Effects of ionizing radiation on the adhesive interaction of human tumor and endothelial cells in vitro." Clinical & experimental metastasis. 1997 Jan; 15(1):12-8.
1995 Sep 30
Fenton BM, Kiani MF, Siemann DW. "Should direct measurements of tumor oxygenation relate to the radiobiological hypoxic fraction of a tumor?" International journal of radiation oncology, biology, physics.. 1995 Sep 30; 33(2):365-73.
1995 May
Fenton BM. "The effects of carbogen and nicotinamide on intravascular oxyhaemoglobin saturations in SCCVII and KHT murine tumours." British journal of cancer.. 1995 May; 71(5):945-9.
1995 Apr
Kiani MF, Fenton BM. "Inherent cellular differences may explain the dissimilar survival of RIF-1 and KHT tumour cells under aerobic and hypoxic conditions." International journal of radiation biology.. 1995 Apr; 67(4):449-52.
1995 Jan
Fenton BM, Raubertas RF, Boyce DJ. "Quantification of micro-regional heterogeneities in tumor oxygenation using intravascular HbO2 saturations." Radiation research.. 1995 Jan; 141(1):49-56.
1995
Fenton BM, Siemann DW. "Are direct measures of tumor oxygenation reflective of changes in tumor radiosensitivity following oxygen manipulation?" Acta oncologica (Stockholm, Sweden). 1995 34(3):307-11.
1994 Jun 15
Fenton BM, Boyce DJ. "Micro-regional mapping of HbO2 saturations and blood flow following nicotinamide administration." International journal of radiation oncology, biology, physics.. 1994 Jun 15; 29(3):459-62.
1994
Fenton BM, Siemann DW. "Investigations of perfusion-limited hypoxia and oxygenation in the KHT sarcoma." Advances in experimental medicine and biology. 1994 361:627-34.
1993 Jul
Fenton BM, Way BA. "Vascular morphometry of KHT and RIF-1 murine sarcomas." Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 1993 Jul; 28(1):57-62.
1992
Fenton BM, Sutherland RM. "Effect of flunarizine on micro-regional distributions of intravascular HbO2 saturations in RIF-1 and KHT sarcomas." International journal of radiation oncology, biology, physics.. 1992 22(3):447-50.
1991 Jun
Fenton BM, Raubertas RF, Sutherland RM. "Time-dependent effects of anesthetic agents on 31P NMR high-energy phosphates in KHT and RIF-1 fibrosarcomas." NMR in biomedicine.. 1991 Jun; 4(3):137-41.
1991
Fenton BM, Sutherland RM. "Effects of anaesthetic agent on [31P]NMR high-energy phosphates and regional distributions of intravascular oxyhaemoglobin saturations." International journal of radiation biology.. 1991 60(1-2):115-9.
1990 Mar 15
Mueller-Klieser W, Schaefer C, Walenta S, Rofstad EK, Fenton BM, Sutherland RM. "Assessment of tumor energy and oxygenation status by bioluminescence, nuclear magnetic resonance spectroscopy, and cryospectrophotometry." Cancer research.. 1990 Mar 15; 50(6):1681-5.
1990
Fenton BM, Gayeski TE. "Determination of microvascular oxyhemoglobin saturations using cryospectrophotometry." The American journal of physiology.. 1990 259(6 Pt 2):H1912-20.
1989 Apr
Rofstad EK, DeMuth P, Fenton BM, Ceckler TL, Sutherland RM. "31P NMR spectroscopy and HbO2 cryospectrophotometry in prediction of tumor radioresistance caused by hypoxia." International journal of radiation oncology, biology, physics.. 1989 Apr; 16(4):919-23.
1988 Oct 1
Rofstad EK, DeMuth P, Fenton BM, Sutherland RM. "31P nuclear magnetic resonance spectroscopy studies of tumor energy metabolism and its relationship to intracapillary oxyhemoglobin saturation status and tumor hypoxia." Cancer research.. 1988 Oct 1; 48(19):5440-6.
1988 May
Rofstad EK, Fenton BM, Sutherland RM. "Intracapillary HbO2 saturations in murine tumours and human tumour xenografts measured by cryospectrophotometry: relationship to tumour volume, tumour pH and fraction of radiobiologically hypoxic cells." British journal of cancer.. 1988 May; 57(5):494-502.
1988
Fenton BM, Rofstad EK, Degner FL, Sutherland RM. "Cryospectrophotometric determination of tumor intravascular oxyhemoglobin saturations: dependence on vascular geometry and tumor growth." Journal of the National Cancer Institute.. 1988 80(20):1612-9.
1985 Apr
Fenton BM, Wilson DW, Cokelet GR. "Analysis of the effects of measured white blood cell entrance times on hemodynamics in a computer model of a microvascular bed." Pflügers Archiv : European journal of physiology.. 1985 Apr; 403(4):396-401.
1985 Jan
Fenton BM, Carr RT, Cokelet GR. "Nonuniform red cell distribution in 20 to 100 micrometers bifurcations." Microvascular research. 1985 Jan; 29(1):103-26.
1982
Fenton,B.M.; Cokelet,G.R.; LaCelle,P.L.;. "Influence of wall surface on the flow of blood through endothelial-lined glass tubes". Int.J.Microcirc.(Clin.and Expt.). 1982; 1: 157-162.
1981 Jul
Worthen DM, Fenton BM, Rosen P, Zweifach B. "Morphometry of diabetic conjunctival blood vessels." Ophthalmology.. 1981 Jul; 88(7):655-7.
1981
Fenton,B.M.; Zweifach,B.W.;. "Microcirculatory model relating geometrical variation to changes in pressure and flow rate". Annals Biomed.Eng.. 1981; 9: 303-321.
1981
Zweifach,B.W.; Schmid-Schonbein,G.; Fenton,B.;. "Morphometric analysis of the microcirculation". Biblthca.Anat.. 1981; 20: 1-4.
1979 Sep
Fenton BM, Zweifach BW, Worthen DM. "Quantitative morphometry of conjunctival microcirculation in diabetes mellitus." Microvascular research. 1979 Sep; 18(2):153-66.

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