Patricia J. Sime, M.D.

Patricia J. Sime, M.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 692
Rochester, NY 14642

Office: (585) 275-4161
Fax: (585) 273-1171


The biographical information for Patricia J. Sime, M.D. is not currently available.


Peroxisome Proliferator-Activated Receptor (PPAR) Expression in Human Body Fluids, Platelets and Secretions

United States Serial NO.: 10/576,824
Filed Date: October 22, 2004
Title: Peroxisome Proliferator-Activated Receptor Gamma (PPARy) and/or Retinoic Acid Receptor (RXR) Agonst To Inhibit Platelet Functions
Invented by: Richard Phipps, Patricia Sime, Neil Blumberg
Over-Trimethylation of 27-Lysine on Histone 3 in Human Idiopathic Pulmonary Fibrosis and Silica Mouse Model

United States Serial NO.: 13/126,875
Filed Date: November 2, 2009
Title: Methods of Diagnosing and Treating Fibrosis
Invented by: Xin Lin, Jia Guo, Steve Georas, Patricia Sime

Recent Journal Articles

Showing the 5 most recent journal articles. 91 available »

2014 Jun 1
Lugade AA, Bogner PN, Thatcher TH, Sime PJ, Phipps RP, Thanavala Y. "Cigarette smoke exposure exacerbates lung inflammation and compromises immunity to bacterial infection." The Journal of immunology : official journal of the American Association of Immunologists.. 2014 Jun 1; 192(11):5226-35. Epub 2014 Apr 21.
2014 Jun
Thannickal VJ, Henke CA, Horowitz JC, Noble PW, Roman J, Sime PJ, Zhou Y, Wells RG, White ES, Tschumperlin DJ. "Matrix biology of idiopathic pulmonary fibrosis: a workshop report of the national heart, lung, and blood institute." The American journal of pathology.. 2014 Jun; 184(6):1643-51. Epub 2014 Apr 13.
2014 May 1
Yao H, Sundar IK, Ahmad T, Lerner C, Gerloff J, Friedman AE, Phipps RP, Sime PJ, McBurney MW, Guarente LP, Rahman I. "SIRT1 protects against cigarette smoke-induced lung oxidative stress via a FOXO3-dependent mechanism." American journal of physiology. Lung cellular and molecular physiology.. 2014 May 1; 306(9):L816-28. Epub 2014 Mar 14.
2014 May
Jeon KI, Kulkarni A, Woeller CF, Phipps RP, Sime PJ, Hindman HB, Huxlin KR. "Inhibitory effects of PPAR? ligands on TGF-?1-induced corneal myofibroblast transformation." The American journal of pathology.. 2014 May; 184(5):1429-45. Epub 2014 Mar 17.
2014 Jan 15
Blackwell TS, Tager AM, Borok Z, Moore BB, Schwartz DA, Anstrom KJ, Bar-Joseph Z, Bitterman P, Blackburn MR, Bradford W, Brown KK, Chapman HA, Collard HR, Cosgrove GP, Deterding R, Doyle R, Flaherty KR, Garcia CK, Hagood JS, Henke CA, Herzog E, Hogaboam CM, Horowitz JC, King TE, Loyd JE, Lawson WE, Marsh CB, Noble PW, Noth I, Sheppard D, Olsson J, Ortiz LA, O'Riordan TG, Oury TD, Raghu G, Roman J, Sime PJ, Sisson TH, Tschumperlin D, Violette SM, Weaver TE, Wells RG, White ES, Kaminski N, Martinez FJ, Wynn TA, Thannickal VJ, Eu JP. "Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report." American journal of respiratory and critical care medicine.. 2014 Jan 15; 189(2):214-22.

Current Appointments

Chief - Department of Medicine, Pulmonary Diseases and Critical Care (SMD)
C. Jane Davis & C. Robert Davis Distinguished Professor in Pulmonary Medicine - Department of Medicine, Pulmonary Diseases and Critical Care (SMD)
Professor - Department of Medicine, Pulmonary Diseases and Critical Care (SMD) - Primary
Professor - Cancer Center
Professor - Department of Environmental Medicine (SMD)
Professor - Department of Microbiology and Immunology (SMD)


Pulmonary Disease - American Board of Internal Medicine
Internal Medicine - American Board of Internal Medicine


MD | Medicine | UK-U Edinburgh Fac Med1988
BS | Pathology | UK-U Edinburgh Fac Med1984

Post-Doctoral Training & Residency

Fellowship in Pulmonary at Royal Infirmary of Edinburgh03/01/1998 - 09/30/1999
Fellowship in Pulmonary at Mcmaster Univ, Canada11/01/1993 - 02/28/1998
Fellowship in Pulmonary at Royal Infirmary of Edinburgh03/01/1992 - 11/01/1993
Residency in General Internal Medicine at Borders General Hospital03/01/1991 - 02/28/1992
Residency in General Internal Medicine at Western General Hospitals08/01/1989 - 02/28/1991
Internship in Internal Medicine/General Surgery at Royal Infirmary of Edinburgh08/01/1988 - 07/31/1989