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Marc B. Lande, M.D., M.P.H.

Marc B. Lande, M.D., M.P.H.

Pediatrics , Pediatric Nephrology

UR Medicine Faculty The University of Rochester Medical Faculty Group (URMFG) consists of over 900 specialist and primary care providers spanning 19 departments. URMFG is certified by the National Committee for Quality Assurance.
Accountable Health Partner Accountable Health Partners (AHP) is a network of over 2,000 community and UR medical faculty and a dozen leading hospitals throughout the region. AHP offers a full range of care.
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Contact

Appointment (585) 275-9784
Fax (585) 756-8054

About Me

Dr. Lande serves as the Co-Director of the Pediatric Hypertension and Lipid Clinic and is the Pediatric Nephrologist representative to the URMC Solid Organ Transplant Program.

Specific Clinical Interest include:
General Nephrology
Dialysis
Renal Transplant
ICU Nephrology

Professional Background

Fellowship Director, Pediatric Nephrology
Co-Director, Pediatric Hypertension and Lipid Clinic, URMC

Faculty Appointments

Professor - Department of Pediatrics, Pediatric Nephrology (SMD)

Chief - Department of Pediatrics, Pediatric Nephrology (SMD)

Credentials

Residency & Fellowship

Fellowship, Pediatric Nephrology, Boston Children's Hospital (USA). 1991 - 1994

Residency, Pediatrics, Golisano Children's Hospital-University of Rochester. 1987 - 1989

Internship, Pediatrics, Golisano Children's Hospital-University of Rochester. 1986 - 1987

Education

MD | University of Pennsylvania School of Dental Medicine. 1986

Awards

Visiting Professor of Pediatric Nephrology at Emory School of Medicine. 2017

Society for Pediatric Research Election (SPR). 2008

American College of Cardiology Foundation/Pfizer Visiting Professor in Cardiovascular Medicine Award. 2006

Rose Award (OHSU). 1997

Rose Award (OHSU). 1996

Henry Christian Memorial Award. 1993

Commissioned Officer Service Award. 1990

Gilbert Forbes Resident Research Award. 1988

Raven Society (University of Virginia). 1982

Phi Beta Kappa ( University of Virginia). 1981

Research

Hypertension is estimated to affect 50 million Americans and is a leading cause of cardiovascular disease, stroke, and kidney disease. Although such morbid events as stroke and myocardial infarction are uncommon in childhood, it is clear that the origins of cardiovascular disease and essential hyper...
Hypertension is estimated to affect 50 million Americans and is a leading cause of cardiovascular disease, stroke, and kidney disease. Although such morbid events as stroke and myocardial infarction are uncommon in childhood, it is clear that the origins of cardiovascular disease and essential hypertension begin early in life and that hypertensive end-organ damage may occur at a young age. Understanding the early time course in how hypertension affects the susceptible organs is important, so that strategies to prevent the development of target-organ damage can be developed.

Dr. Lande is studying the neurocognitive effects of hypertension in children and determining any potential benefit of antihypertensive therapy on cognition. Since 2010, I have led an NIH-funded multicenter research team including investigators from the University of Rochester, Emory University, Maimonides Medical Center, University of Houston, Texas, and the University of North Carolina. This is a multidisciplinary effort including pediatric nephrologists, cardiologists, and neuropsychologists. He is also the site PI for two clinical research collaborative networks, the Chronic Kidney Disease in Children Study (CKiD) and the Study of Hypertension in Pediatrics – Adults Hypertension Onset in Youth (SHIP AHOY). In addition serves on the Neurocognitive subcommittee for CKiD and the Steering Committee for SHIP AHOY.

Publications

Journal Articles

Blood pressure and left ventricular mass index in healthy adolescents.

Daimee UA, Lande MB, Tang W, Tu XM, Veazie P, Bisognano JD, Block R, Teeters JC

Blood pressure monitoring.. 2017 February 22 (1):48-50. Epub 1900 01 01.

Neurocognitive Function in Children with Primary Hypertension.

Lande MB, Batisky DL, Kupferman JC, Samuels J, Hooper SR, Falkner B, Waldstein SR, Szilagyi PG, Wang H, Staskiewicz J, Adams HR

The Journal of pediatrics.. 2017 January 180 :148-155.e1. Epub 09/29/2016.

Association of blood pressure variability and neurocognition in children with chronic kidney disease.

Lande MB, Mendley SR, Matheson MB, Shinnar S, Gerson AC, Samuels JA, Warady BA, Furth SL, Hooper SR

Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2016 November 31 (11):2137-44. Epub 06/05/2016.

Effect of elevated blood pressure on quality of life in children with chronic kidney disease.

Wong C, Gerson A, Hooper SR, Matheson M, Lande M, Kupferman J, Furth S, Warady B, Flynn J,

Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2016 July 31 (7):1129-36. Epub 02/08/2016.

Neurocognitive, Social-Behavioral, and Adaptive Functioning in Preschool Children with Mild to Moderate Kidney Disease.

Hooper SR, Gerson AC, Johnson RJ, Mendley SR, Shinnar S, Lande MB, Matheson MB, Gipson DS, Morgenstern B, Warady BA, Furth SL

Journal of developmental and behavioral pediatrics : JDBP.. 2016 April 37 (3):231-8. Epub 1900 01 01.

Executive function and cerebrovascular reactivity in pediatric hypertension.

Ostrovskaya MA, Rojas M, Kupferman JC, Lande MB, Paterno K, Brosgol Y, Pavlakis SG

Journal of child neurology.. 2015 April 30 (5):543-6. Epub 07/22/2013.

Sleep disordered breathing as measured by SRBD-PSQ and neurocognition in children with hypertension.

Lande MB, Hooper SR, Batisky DL, Kupferman JC, Szilagyi PG, Samuels JA, Adams HR

American journal of hypertension.. 2015 April 28 (4):552-8. Epub 09/20/2014.

Duration of chronic kidney disease reduces attention and executive function in pediatric patients.

Mendley SR, Matheson MB, Shinnar S, Lande MB, Gerson AC, Butler RW, Warady BA, Furth SL, Hooper SR

Kidney international.. 2015 April 87 (4):800-6. Epub 09/24/2014.

Cognitive function in hypertensive children.

Lande MB, Kupferman JC

Current hypertension reports.. 2015 January 17 (1):508. Epub 1900 01 01.

Recurrent gain of function mutation in calcium channel CACNA 1H causes early onset hypertension and primary aldosteronism

Scholl UI; Stolting G; Nelson-Williams C; Vichot AA; Choi M; Loring E; Prasad ML; Goh G; Carling T; Juhlin CC; Quack I; Rump LC; Thiel A; Lande MB; Frazier BG; Rasoulpour M; Bowlin DL; Sethna CB; Trachtman H; Fahlke C; Lifton RP.

Elife. 2015; .

Neurocognition in children with autosomal recessive polycystic kidney disease in the CKiD cohort study.

Hartung EA, Matheson M, Lande MB, Dell KM, Guay-Woodford LM, Gerson AC, Warady BA, Hooper SR, Furth SL

Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2014 October 29 (10):1957-65. Epub 05/15/2014.

Pediatric hypertension: the year in review.

Lande MB, Kupferman JC

Clinical pediatrics.. 2014 April 53 (4):315-9. Epub 08/19/2013.

Blood pressure and school performance.

Lande MB, Kupferman JC, Hooper SR, Pavlakis SG, Batisky DL, Adams HR

Psychosomatic medicine.. 2014 February 76 (2):163-6. Epub 01/26/2014.

Primary hypertension and neurocognitive and executive functioning in school-age children.

Kupferman JC, Lande MB, Adams HR, Pavlakis SG

Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2013 March 28 (3):401-8. Epub 06/13/2012.

Treatment of Pediatric Hypertension: Lessons Learned from Recent Studies

Lande MB; Kupferman JC.

Current Cardiovascular Risk Reports. 2013; 7(5): 307-314.

A multicenter study of neurocognition in children with hypertension: methods, challenges, and solutions.

Lande MB, Adams HR, Kupferman JC, Hooper SR, Szilagyi PG, Batisky DL

Journal of the American Society of Hypertension : JASH.. 2013 7 (5):353-62. Epub 06/20/2013.

Neurocognitive alterations in hypertensive children and adolescents.

Lande MB, Kupferman JC, Adams HR

The journal of clinical hypertension.. 2012 June 14 (6):353-9. Epub 05/21/2012.

Casual Blood Pressure and Neurocognitive Function in Children with Chronic Kidney Disease: A Report of the Children with Chronic Kidney Disease Cohort Study

Lande MB, Gerson AC, Hooper SR, Cox C, Matheson M, Mendley SR, Gipson DS, Wong Cynthia, Warady BA, Furth SL, Flynn JT.

Clin J Am Soc Nephrol. 2011; 6: 1831-37.

Neurocognitive functioning of children and adolescents with mild-to-moderate chronic kidney disease

Hooper SR, Gerson AC, Butler RW, Gipson DS, Mendley SR, Lande MB, Shinnar S, Wentz A, Matteson M, Cox C, Furth SL, Warady BA.

Clin J Am Soc Nephrol. 2011; 6: 1824-30.

Health-related quality of life of children with mild to moderate chronic kidney disease

Gerson AC, Wentz A, Abraham AG, Mendley SR, Hooper SR, Butler RW, Gipson DS, Lande MB, Shinnar S, Moxey-Mims MM, Warady BA, Furth SL.

Pediatrics. 2010; 125(2): e349-57.

Parental assessment of executive function and internalizing and externalizing behavior in primary hypertension after anti-hypertensive therapy

Lande MB, Adams H, Falkner B, Waldstein SR, Schwartz GJ, Szilagyi PG, Wang H, Palumbo D.

J Pediatr. 2010; 157(1): 114-9.

A simple method of measuring thoracic aortic pulse wave velocity in children: Methods and normal values.

Jo CO, Lande MB, Meagher CC, Wang H, Vermilion RP.

J Am Soc Echocardiogr. 2010; 23: 735-40.

Learning and attention problems among children with pediatric primary hypertension

Adams HR, Szilagyi PG, Gebhardt L, Lande MB.

Pediatrics. 2010; 126(6): e1425-9.

Treatment of hypertension in children and adolescents.

Lande MB, Flynn JT.

Pediatr Nephrol. 2009; 24(10): 1939-49.

Parental Assessments of Internalizing and Externalizing Behavior and Executive Function in Children with Primary Hypertension

Lande MB, Adams H, Falkner B, Waldstein SR, Schwartz GJ, Szilagyi P, Wang H, Palumbo D.

J Pediatr. 2009; 154: 207-12.

Elevated blood pressure, race/ethnicity, and C-reactive protein in children and adolescents.

Lande MB, Pearson TA, Vermilion RP, Auinger P, Fernandez ID.

Pediatrics. 2008; 122: 1252-7.

Left ventricular mass index in children with white coat hypertension.

Lande MB, Meagher CC, Fisher SG, Belani P, Wang H, Rashid M.

J Pediatr. 2008; 153: 50-4.

Effects of childhood primary hypertension on carotid intima media thickness: a matched controlled study.

Lande MB, Carson NL, Roy J, Meagher CC

Hypertension.. 2006 July 48 (1):40-4. Epub 05/30/2006.

Medical evaluation and treatment of urolithiasis.

Nicoletta JA, Lande MB

Pediatric clinics of North America.. 2006 June 53 (3):479-91, vii. Epub 1900 01 01.

Neurocognitive outcomes in children with chronic kidney disease: Current findings and contemporary endeavors.

Gerson AC, Butler R, Moxey-Mims M, Wentz A, Shinnar S, Lande MB, Mendley SR, Warady BA, Furth SL, Hooper SR.

Ment Retard Dev Disabil Res Rev. 2006; 12: 208-215.

Granulomatous interstitial nephritis associated with bone marrow transplantation.

Schwaderer AL, Arend L, Lande MB

Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2005 April 20 (4):539-42. Epub 02/03/2005.

Role of urinary supersaturation in the evaluation of children with urolithiasis.

Lande MB, Varade W, Erkan E, Niederbracht Y, Schwartz GJ

Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2005 April 20 (4):491-4. Epub 02/17/2005.

Elevated blood pressure and decreased cognitive function among school-age children and adolescents in the United States.

Lande MB, Kaczorowski JM, Auinger P, Schwartz GJ, Weitzman M

The Journal of pediatrics.. 2003 December 143 (6):720-4. Epub 1900 01 01.

Vitamin E therapy in IgA nephropathy: a double-blind, placebo-controlled study.

Chan JC, Mahan JD, Trachtman H, Scheinman J, Flynn JT, Alon US, Lande MB, Weiss RA, Norkus EP

Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2003 October 18 (10):1015-9. Epub 08/12/2003.

Long versus standard initial steroid therapy for children with the nephrotic syndromeA report from the Southwest Pediatric Nephrology Study Group.

Lande MB, Gullion C, Hogg RJ, Gauthier B, Shah B, Leonard MB, Bonilla-Felix M, Nash M, Roy S, Strife CF, Arbus G

Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2003 April 18 (4):342-6. Epub 03/21/2003.

Family structure and the course of steroid-sensitive nephrotic syndrome.

Soliday E, Lande MB

Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2002 January 17 (1):41-4. Epub 1900 01 01.

Daily reports and pooled time series analysis: pediatric psychology applications.

Soliday E, Moore KJ, Lande MB

Journal of pediatric psychology.. 2002 27 (1):67-76. Epub 1900 01 01.

Membranous nephropathy associated with chronic immune thrombocytopenic purpura in childhood.

Lande MB, Thomas GA, Houghton DC

American journal of kidney diseases : the official journal of the National Kidney Foundation.. 2001 May 37 (5):E40. Epub 1900 01 01.

Family environment, child behavior, and medical indicators in children with kidney disease.

Soliday E, Kool E, Lande MB

Child psychiatry and human development.. 2001 31 (4):279-95. Epub 1900 01 01.

Effect of grapefruit juice on cyclosporin A pharmacokinetics in pediatric renal transplant patients.

Brunner LJ, Pai KS, Munar MY, Lande MB, Olyaei AJ, Mowry JA

Pediatric transplantation.. 2000 November 4 (4):313-21. Epub 1900 01 01.

Variability among pediatric nephrologists in the initial therapy of nephrotic syndrome.

Lande MB, Leonard MB

Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2000 August 14 (8-9):766-9. Epub 1900 01 01.

Acyclovir prophylaxis of varicella in children with renal disease receiving steroids.

Goldstein SL, Somers MJ, Lande MB, Brewer ED, Jabs KL

Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 2000 April 14 (4):305-8. Epub 1900 01 01.

Psychosocial adjustment in children with kidney disease.

Soliday E, Kool E, Lande MB

Journal of pediatric psychology.. 2000 March 25 (2):93-103. Epub 1900 01 01.

Behavioral effects of corticosteroids in steroid-sensitive nephrotic syndrome.

Soliday E, Grey S, Lande MB

Pediatrics.. 1999 October 104 (4):e51. Epub 1900 01 01.

Kidney transplantation in children: a single center experience.

Lashley DB, Barry JM, Demattos AM, Lande MB, Mowry JA

The Journal of urology.. 1999 June 161 (6):1920-5. Epub 1900 01 01.

Immune complex disease associated with Epstein-Barr virus infectious mononucleosis.

Lande MB, Mowry JA, Houghton DC, White CR, Borzy MS

Pediatric nephrology : journal of the International Pediatric Nephrology Association.. 1998 October 12 (8):651-3. Epub 1900 01 01.

Transplantation of adult kidneys into small children

Barry JM, Reller KS, Lande MB, Mowry JA, Jenkins R.

Akt. Urol. 1998; 29: 239-245.

Phosphorylation of aquaporin-2 does not alter the membrane water permeability of rat papillary water channel-containing vesicles.

Lande MB, Jo I, Zeidel ML, Somers M, Harris HW

The Journal of biological chemistry.. 1996 March 8271 (10):5552-7. Epub 1900 01 01.

Long-term outcome of Haemophilus influenzae meningitis in Navajo Indian children.

D'Angio CT, Froehlke RG, Plank GA, Meehan DJ, Aguilar CM, Lande MB, Hugar L

Archives of pediatrics & adolescent medicine.. 1995 September 149 (9):1001-8. Epub 1900 01 01.

The relationship between membrane fluidity and permeabilities to water, solutes, ammonia, and protons.

Lande MB, Donovan JM, Zeidel ML

The Journal of general physiology.. 1995 July 106 (1):67-84. Epub 1900 01 01.

Human red cell Aquaporin CHIP. II. Expression during normal fetal development and in a novel form of congenital dyserythropoietic anemia.

Agre P, Smith BL, Baumgarten R, Preston GM, Pressman E, Wilson P, Illum N, Anstee DJ, Lande MB, Zeidel ML

The Journal of clinical investigation.. 1994 September 94 (3):1050-8. Epub 1900 01 01.

Determinants of apical membrane permeabilities of barrier epithelia.

Lande MB, Priver NA, Zeidel ML

The American journal of physiology.. 1994 August 267 (2 Pt 1):C367-74. Epub 1900 01 01.

Reversible Fanconi syndrome associated with valproate therapy.

Lande MB, Kim MS, Bartlett C, Guay-Woodford LM

The Journal of pediatrics.. 1993 August 123 (2):320-2. Epub 1900 01 01.

The role of syphilis serology in the evaluation of suspected sexual abuse.

Lande MB, Richardson AC, White KC

The Pediatric infectious disease journal.. 1992 February 11 (2):125-7. Epub 1900 01 01.

Books

Pediatric Hypertension (2017)

Chapter: Cognitive and Behavioral Aspects of Childhood Hypertension

Authors: Lande MB, Kupferman JC, Adams HR

Publisher: Springer, New York 2017

Nelson Textbook of Pediatrics (2016)

Chapter: Systemic Hypertension

Authors: Lande MB

Publisher: WB Saunders, Philadelphia 2016

Pediatric Hypertension (2013)

Chapter: Cognitive and Behavioral Aspects of Childhood Hypertension

Authors: Lande MB, Kupferman JC, Adams HR

Publisher: Springer, New York 2013

Nelson Textbook of Pediatrics, Nineteenth Edition (2011)

Chapter: Systemic Hypertension

Authors: Lande MB, RM Kleigman, BF Stanton, J St. Geme, N Schor, RE Behrman, eds

Publisher: WB Saunders, Philadelphia 2011

Performing Preventive Services: A Bright Futures Handbook (2010)

Chapter: Blood Pressure

Authors: Lande MB, Varade W. S Tanski, L Garfunkel, P Duncan, M Weitzman

Publisher: American Academy of Pediatrics 2010

Ratings & Reviews

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