Eileen M. Redmond, Ph.D.

Eileen M. Redmond, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box SURG
Rochester, NY 14642

Office: (585) 275-2870
Administrative: (585) 275-1488
Lab: (585) 275-2902

Journal Articles

Showing all 65 journal articles available.

2014 Mar
Kennedy E; Greene C; Hakimjavadi R; Mooney CJ; Fitzpatrick E; Collins LE; Loscher CL; Guha S; Morrow D; Redmond EM; Cahill PA. "Embryonic rat vascular smooth muscle cells revisited - a model for neonatal, neointimal vSMC or differentiated vascular stem cells?". Vascular Cell. 2014; 6(1).
2014 Feb
Doyle AJ; Redmond EM; Gillespie DL; Knight PA; Cullen JP; Cahill PA; Morrow D. "Differential Expression of Hedgehog/Notch and Transforming Growth Factor-Beta in Human Abdominal Aortic Aneurysms." J Vasc Surg. 2014; .
2014
Redmond EM; Liu W; Hamm K, Hatch E, Cahill PA, Morrow D. "Perivascular Delivery of Notch1 siRNA Inhibits Injury-induced Arterial Remodeling." PLoS One. 2014; 9(1): e84122. Link
2013 Aug
Redmond EM; Hamm K; Cullen JP; Hatch E; Cahill PA; Morrow D. "Inhibition of Patched-1 Prevents Injury-induced Neointimal Hyperplasia." Arteriosclerosis, Thrombosis and Vascular Biology. 2013; 33(8): 1960-1964.
2012 Apr
Cahill PA; Redmond EM. "Alcohol and Cardiovascular Disease--Modulation of Vascular Cell Function". Nutrients. 2012; 4(4): 297-318. Link
2012 Mar
Redmond EM; Cahill PA. "The NOX-ROS connection: targeting Nox1 control of N-cadherin shedding in vascular smooth muscle cells." Cardiovasc Res.. 2012; 93(3): 386-387.
2011 May
Guha S; Cullen JP; Morrow D; Colombo A; Lally C; Walls D; Redmond EM; Cahill PA. "Glycogen synthase kinase 3 beta (GSK-3b) positively regulates Notch signaling in vascular smooth muscle cells; role in cell proliferation and survival." Basic Res Cardiol. 2011; .
2011
Zhao J; Wang W; Hoon Ha C; Kim JY; Wong C; Redmond EM; Hamik A; Jain MK; Feng G-S; Jin ZG. "Endothelial Gab1 is crucial for postnatal angiogenesis". Arteriosclerosis, thrombosis, and vascular biology. 2011; .
2011
Walshe T; Connell P; Cryan L; Ferguson G; Gardiner T; Morrow D; Redmond EM; O'Brien C; Cahill PA. "Microvascular retinal endothelial and pericyte cell apoptosis in vitro: role of Hedgehog and Notch." Invest Ophthamol Vis Sci. 2011; .
2011
Liu W, Redmond EM, Morrow D, Cullen JP. "Differential effects of daily-moderate versus weekend-binge alcohol consumption on atherosclerotic plaque development in mice." Atherosclerosis. 2011 219(2):448-54. Epub 2011 Aug 30.
2011
Redmond EM, Guha S, Walls D, Cahill PA. "Investigational Notch and Hedgehog inhibitors--therapies for cardiovascular disease." Expert opinion on investigational drugs. 2011 20(12):1649-64. Epub 2011 Oct 18.
2010
Banerjee S; Lin C-F; Skinner K; Schiffhauer L; Peacock J; Hicks D; Redmond EM; Morrow D; Huston A; Shayne M; Langstein H; Miller-Graziano C; Strickland J; O'Donoghue L, De A. "Heat shock protein 27 differentiates tolerogenic macrophages that may support human breast cancer progression." Cancer Research. 2010; .
2010
Morrow D, Cullen JP, Liu W, Cahill PA, Redmond EM. "Alcohol inhibits smooth muscle cell proliferation via regulation of the Notch signaling pathway." Arteriosclerosis, thrombosis, and vascular biology.. 2010 30(12):2597-603. Epub 2010 Oct 07.
2009 Oct
Morrow D; Avissar NE; Toia L; Redmond EM; Watson TJ; Jones C; Raymond DP; Litle V; Godfrey T; Peters JH. "Pathogenesis of Barrett's Esophagus; Bile Acids Inhibit the Notch Signaling Pathway with Induction of CDX2 Gene Expression in Human Esophageal Cells." Surgery. 2009; 146(4): 714-721.
2009 Jul
Morrow D, Cullen JP, Liu W, Guha S, Sweeney C, Birney YA, Collins N, Walls D, Redmond EM, Cahill PA. "Sonic Hedgehog induces Notch target gene expression in vascular smooth muscle cells via VEGF-A." Arteriosclerosis, thrombosis, and vascular biology.. 2009 Jul; 29(7):1112-8. Epub 2009 Apr 30.
2009 Jun
Redmond EM, Morrow D, Kundimi S, Miller-Graziano CL, Cullen JP. "Acetaldehyde stimulates monocyte adhesion in a P-selectin- and TNFalpha-dependent manner." Atherosclerosis. 2009 Jun; 204(2):372-80. Epub 2008 Oct 18.
2009
Redmond EM; Morrow D; Kundimi S; Miller-Grazian CL; Cullen JP. "Acetaldehyde stimulates monocyte adhesion in a P-selectin- and TNFalpha-dependent manner". Atherosclerosis. 2009; 204(2): 372-80.
2008 Nov
Skill NJ; Wang Y-N; Theodorakis NG; Redmond EM; Cahill PA; Sitzmann JV. "Role of cyclooxygenase isoforms in prostacyclin biosynthesis and murine pre-hepatic portal hypertension". Am J Physiol. 2008; 295(5): G953-64.
2008 Jul 15
Morrow D, Cullen JP, Cahill PA, Redmond EM. "Ethanol stimulates endothelial cell angiogenic activity via a Notch- and angiopoietin-1-dependent pathway." Cardiovascular research.. 2008 Jul 15; 79(2):313-21. Epub 2008 Apr 30.
2008
Morrow D, Guha S, Sweeney C, Birney Y, Walshe T, O'Brien C, Walls D, Redmond EM, Cahill PA. "Notch and vascular smooth muscle cell phenotype." Circulation research.. 2008 103(12):1370-82.
2007 Nov
Cullen JP, Morrow D, Jin Y, von Offenberg Sweeney N, Sitzmann JV, Cahill PA, Redmond EM. "Resveratrol inhibits expression and binding activity of the monocyte chemotactic protein-1 receptor, CCR2, on THP-1 monocytes." Atherosclerosis. 2007 Nov; 195(1):e125-33. Epub 2007 May 17.
2007 Jun
Morrow D, Cullen JP, Cahill PA, Redmond EM. "Cyclic strain regulates the Notch/CBF-1 signaling pathway in endothelial cells: role in angiogenic activity." Arteriosclerosis, thrombosis, and vascular biology.. 2007 Jun; 27(6):1289-96. Epub 2007 Mar 29.
2007 Jan
Cummins PM; von Offenberg Sweeney N; Killeen MT; Birney YA; Redmond EM; Cahill PA. "Cyclic strain-mediated matrix metalloproteinase regulation within the vascular endothelium: A force to be reckoned with." AJP Heart and Circulatory Physiol. 2007; 292(1): H28-42.
2007 Jan
Morrow D, Sweeney C, Birney YA, Guha S, Collins N, Cummins PM, Murphy R, Walls D, Redmond EM, Cahill PA. "Biomechanical regulation of hedgehog signaling in vascular smooth muscle cells in vitro and in vivo." American journal of physiology. Cell physiology.. 2007 Jan; 292(1):C488-96. Epub 2006 Aug 30.
2007
Cullen JP, Morrow D, Jin Y, Curley B, Robinson A, Sitzmann JV, Cahill PA, Redmond EM. "Resveratrol, a polyphenolic phytostilbene, inhibits endothelial monocyte chemotactic protein-1 synthesis and secretion." Journal of vascular research. 2007 44(1):75-84. Epub 2006 Dec 21.
2005 Nov
Morrow D; Scheller A; Birney Y; Sweeney C; Ghua S; Cummins PM; Murphy R; Walls D; Redmond EM; Cahill PA. "Notch-mediated CBF-1/RBP-J{kappa}-dependent regulation of human vascular smooth muscle cell phenotype in vitro." Am J Physiol- Cell Physiology. 2005; 289(5): C1188-96. Link
2005 Oct
Cullen JP, Sayeed S, Jin Y, Theodorakis NG, Sitzmann JV, Cahill PA, Redmond EM. "Ethanol inhibits monocyte chemotactic protein-1 expression in interleukin-1{beta}-activated human endothelial cells." American journal of physiology. Heart and circulatory physiology.. 2005 Oct; 289(4):H1669-75. Epub 2005 May 20.
2005 Sep
Cullen JP, Sayeed S, Kim Y, Theodorakis NG, Sitzmann JV, Cahill PA, Redmond EM. "Ethanol inhibits pulse pressure-induced vascular smooth muscle cell migration by differentially modulating plasminogen activator inhibitor type 1, matrix metalloproteinase-2 and -9." Thrombosis and haemostasis.. 2005 Sep; 94(3):639-45.
2005 Apr 8
Von Offenberg Sweeney N, Cummins PM, Cotter EJ, Fitzpatrick PA, Birney YA, Redmond EM, Cahill PA. "Cyclic strain-mediated regulation of vascular endothelial cell migration and tube formation." Biochemical and biophysical research communications.. 2005 Apr 8; 329(2):573-82.
2005 Mar 18
Morrow D, Sweeney C, Birney YA, Cummins PM, Walls D, Redmond EM, Cahill PA. "Cyclic strain inhibits Notch receptor signaling in vascular smooth muscle cells in vitro." Circulation research.. 2005 Mar 18; 96(5):567-75. Epub 2005 Feb 10.
2004 Sep 1
von Offenberg Sweeney N, Cummins PM, Birney YA, Cullen JP, Redmond EM, Cahill PA. "Cyclic strain-mediated regulation of endothelial matrix metalloproteinase-2 expression and activity." Cardiovascular research.. 2004 Sep 1; 63(4):625-34.
2004 Sep
Sweeney C, Morrow D, Birney YA, Coyle S, Hennessy C, Scheller A, Cummins PM, Walls D, Redmond EM, Cahill PA. "Notch 1 and 3 receptor signaling modulates vascular smooth muscle cell growth, apoptosis, and migration via a CBF-1/RBP-Jk dependent pathway." FASEB journal : official publication of the Federation of American Societies for Experimental Biology.. 2004 Sep; 18(12):1421-3. Epub 2004 Jul 09.
2004 Jul
von Offenberg Sweeney N; Cummins PM; Birney YA; Redmond EM; Cahill PA. "Cyclic strain-induced endothelial MMP-2: role in vascular smooth muscle cell migration." Biochem Biopys Res Commun. 2004; 320(2): 325-33. Link
2004
Cullen JP, Nicholl SM, Sayeed S, Sitzmann JV, Okada SS, Cahill PA, Redmond EM. "Plasminogen activator inhibitor-1 deficiency enhances flow-induced smooth muscle cell migration." Thrombosis research.. 2004 114(1):57-65.
2004
Birney YA, Sweeney CH, Cappadona CR, Sitzmann JV, Cummins PM, Redmond EM, Cahill PA. "Pulse pressure-induced transmural fluid flux increases bovine aortic smooth muscle cell apoptosis in a mitogen activated protein kinase dependent manner." Journal of vascular research. 2004 41(4):364-74. Epub 2004 Sep 06.
2003 Oct
Birney Y, Redmond EM, Sitzmann JV, Cahill PA. "Eicosanoids in cirrhosis and portal hypertension." Prostaglandins & other lipid mediators. 2003 Oct; 72(1-2):3-18.
2003 May
Theodorakis NG, Wang YN, Skill NJ, Metz MA, Cahill PA, Redmond EM, Sitzmann JV. "The role of nitric oxide synthase isoforms in extrahepatic portal hypertension: studies in gene-knockout mice." Gastroenterology.. 2003 May; 124(5):1500-8.
2002 Oct 1
Cullen JP, Sayeed S, Sawai RS, Theodorakis NG, Cahill PA, Sitzmann JV, Redmond EM. "Pulsatile flow-induced angiogenesis: role of G(i) subunits." Arteriosclerosis, thrombosis, and vascular biology.. 2002 Oct 1; 22(10):1610-6.
2002 Jun 12
Sayeed S, Cullen JP, Coppage M, Sitzmann JV, Redmond EM. "Ethanol differentially modulates the expression and activity of cell cycle regulatory proteins in rat aortic smooth muscle cells." European journal of pharmacology. 2002 Jun 12; 445(3):163-70.
2001 Mar
Cahill PA, Redmond EM, Sitzmann JV. "Endothelial dysfunction in cirrhosis and portal hypertension." Pharmacology & therapeutics. 2001 Mar; 89(3):273-93.
2001 Jan 30
Redmond EM, Cullen JP, Cahill PA, Sitzmann JV, Stefansson S, Lawrence DA, Okada SS. "Endothelial cells inhibit flow-induced smooth muscle cell migration: role of plasminogen activator inhibitor-1." Circulation.. 2001 Jan 30; 103(4):597-603.
2000 May
Redmond EM, Sitzmann JV, Cahill PA. "Potential mechanisms for cardiovascular protective effect of ethanol." Acta pharmacologica Sinica.. 2000 May; 21(5):385-90.
1999 Jul 10
Cappadona C, Redmond EM, Theodorakis NG, McKillop IH, Hendrickson R, Chhabra A, Sitzmann JV, Cahill PA. "Phenotype dictates the growth response of vascular smooth muscle cells to pulse pressure in vitro." Experimental cell research.. 1999 Jul 10; 250(1):174-86.
1999 Jun 1
Hendrickson RJ, Okada SS, Cahill PA, Yankah E, Sitzmann JV, Redmond EM. "Ethanol inhibits basal and flow-induced vascular smooth muscle cell migration in vitro." The Journal of surgical research. 1999 Jun 1; 84(1):64-70.
1999 Jun
Hendrickson RJ, Cahill PA, Sitzmann JV, Redmond EM. "Ethanol enhances basal and flow-stimulated nitric oxide synthase activity in vitro by activating an inhibitory guanine nucleotide binding protein." The Journal of pharmacology and experimental therapeutics.. 1999 Jun; 289(3):1293-300.
1999 Mar
Hendrickson RJ, Cappadona C, Yankah EN, Sitzmann JV, Cahill PA, Redmond EM. "Sustained pulsatile flow regulates endothelial nitric oxide synthase and cyclooxygenase expression in co-cultured vascular endothelial and smooth muscle cells." Journal of molecular and cellular cardiology.. 1999 Mar; 31(3):619-29.
1999 Feb
Redmond EM, Cahill PA, Hirsch M, Wang YN, Sitzmann JV, Okada SS. "Effect of pulse pressure on vascular smooth muscle cell migration: the role of urokinase and matrix metalloproteinase." Thrombosis and haemostasis.. 1999 Feb; 81(2):293-300.
1998 Dec
Hendrickson RJ; Cahill PA; McKillop IH; Sitzmann JV; Redmond EM. "Ethanol inhibits mitogen activated protein kinase activity and growth of vascular smooth muscle cells in vitro." Eur J Parmacol.. 1998; 362(2-3): 251-9. Link
1998 Nov
Mebazaa A, Wetzel RC, Dodd-o JM, Redmond EM, Shah AM, Maeda K, Maistre G, Lakatta EG, Robotham JL. "Potential paracrine role of the pericardium in the regulation of cardiac function." Cardiovascular research.. 1998 Nov; 40(2):332-42.
1998 Aug
Cahill PA, Hou MC, Hendrickson R, Wang YN, Zhang S, Redmond EM, Sitzman JV. "Increased expression of endothelin receptors in the vasculature of portal hypertensive rats: role in splanchnic hemodynamics." Hepatology : official journal of the American Association for the Study of Liver Diseases.. 1998 Aug; 28(2):396-403.
1998 Jan
Hou MC, Cahill PA, Zhang S, Wang YN, Hendrickson RJ, Redmond EM, Sitzmann JV. "Enhanced cyclooxygenase-1 expression within the superior mesenteric artery of portal hypertensive rats: role in the hyperdynamic circulation." Hepatology : official journal of the American Association for the Study of Liver Diseases.. 1998 Jan; 27(1):20-7.
1998 Jan
Redmond EM, Cahill PA, Sitzmann JV. "Flow-mediated regulation of G-protein expression in cocultured vascular smooth muscle and endothelial cells." Arteriosclerosis, thrombosis, and vascular biology.. 1998 Jan; 18(1):75-83.
1998
Kouretas PC, Hannan RL, Kapur NK, Hendrickson R, Redmond EM, Myers AK, Kim YD, Cahill PA, Sitzmann JV. "Non-anticoagulant heparin increases endothelial nitric oxide synthase activity: role of inhibitory guanine nucleotide proteins." Journal of molecular and cellular cardiology.. 1998 30(12):2669-82.
1997 Jul
Hou MC, Cahill PA, Zhang S, Redmond EM, Sitzmann JV. "Enhanced G-protein-induced relaxation in portal hypertensive rats: role of nitric oxide." Hepatology : official journal of the American Association for the Study of Liver Diseases.. 1997 Jul; 26(1):27-33.
1997
Redmond EM, Cahill PA, Sitzmann JV. "Flow-mediated regulation of endothelin receptors in cocultured vascular smooth muscle cells: an endothelium-dependent effect." Journal of vascular research. 1997 34(6):425-35.
1996 Sep
Cahill PA, Redmond EM, Hodges R, Zhang S, Sitzmann JV. "Increased endothelial nitric oxide synthase activity in the hyperemic vessels of portal hypertensive rats." Journal of hepatology.. 1996 Sep; 25(3):370-8.
1996 Mar
Redmond EM, Cahill PA, Hodges R, Zhang S, Sitzmann JV. "Regulation of endothelin receptors by nitric oxide in cultured rat vascular smooth muscle cells." Journal of cellular physiology.. 1996 Mar; 166(3):469-79.
1996 Feb
Cahill PA, Redmond EM, Wu Y, Sitzmann JV. "Regulation of atrial natriuretic factor receptors in portal hypertensive rabbits." Journal of hepatology.. 1996 Feb; 24(2):185-93.
1995 Sep
Redmond EM, Cahill PA, Sitzmann JV. "Perfused transcapillary smooth muscle and endothelial cell co-culture--a novel in vitro model." In vitro cellular & developmental biology. Animal.. 1995 Sep; 31(8):601-9.
1995 Aug
Cahill PA, Foster C, Redmond EM, Gingalewski C, Wu Y, Sitzmann JV. "Enhanced nitric oxide synthase activity in portal hypertensive rabbits." Hepatology : official journal of the American Association for the Study of Liver Diseases.. 1995 Aug; 22(2):598-606.
1995 Jan 16
Cahill PA, Redmond EM, Foster C, Sitzmann JV. "Nitric oxide regulates angiotensin II receptors in vascular smooth muscle cells." European journal of pharmacology. 1995 Jan 16; 288(2):219-29.
1994 Nov
Redmond EM, Cherian MN, Wetzel RC. "17 beta-Estradiol inhibits flow- and acute hypoxia-induced prostacyclin release from perfused endocardial endothelial cells." Circulation.. 1994 Nov; 90(5):2519-24.
1992
Kent A, Redmond EM, Keenan AK. "The ANF-C receptor is not linked to adenylyl cyclase inhibition in bovine pulmonary artery endothelial cells." Life sciences.. 1992 51(18):1439-44.
1990 Dec
Cahill PA; Redmond EM; Keenan AK. "Vascular atrial natriuretic factor receptor subtypes are not independently regulated by atrial peptides." J Biol Chem. 1990; 265(35): 1896-906. Link
1990 Aug
Redmond EM; Cahill PA; Keenan AK. "Atrial natriuretic factor recognizes two receptor subtypes in endothelial cells cultured from bovine pulmonary artery." FEBS Lett. 1990; 269(1): 157-162.

Books

2013
Redmond EM. "Vascular endothelium- role in the pathophysiology of atherosclerosis.". Vascular Disease: Biology, Medicine, Treatment.. : Wiley-Blackwell, 2013.
2012
Redmond EM , Lally T, Cahill PA.. "Hemodynamic control of vascular smooth muscle cell function.". Vascular Smooth Muscle: Fundamental Biology and Mechanisms of Disease. Hill and Olsen. : Elsevier, 2012.
2002
Redmond EM and Cahill PA. "Alcohol, Vascular Cells and Hemodynamic Forces". Alcohol and Heart Disease. RR Watson and AK Myers. London: Taylor and Francis, 2002. 91-103