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Lisa A. DeLouise, Ph.D., M.P.D.

Lisa A. DeLouise, Ph.D., M.P.D.

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Research Lab

We are bionanomaterials group that investigates novel biomedical devices for diagnostic and therapeutic applications.

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About Me

Faculty Appointments

Associate Professor - Department of Dermatology (SMD)

Associate Professor - Department of Electrical & Computer Engineering (RC) - Joint

Credentials

Education

MPD | Rochester Inst Technology. Product Development. 2001

PhD | Penn State University. Physical Chemistry. 1984

BS | Providence College. Chemistry. 1979

Research

The DeLouise Bio-nanomaterials lab focuses on investigating the interactions of environmental insults on the skin and developing novel approaches to probe these interactions at the single cell and tissue levels which is also important for high content drug discovery.

Skin & the Environment
The DeLouise Bio-nanomaterials lab focuses on investigating the interactions of environmental insults on the skin and developing novel approaches to probe these interactions at the single cell and tissue levels which is also important for high content drug discovery.

Skin & the Environment
Skin is the largest organ of the body by mass and is a main route to contact dermatitis sensitization. A particular interest in the lab is to elucidate the mechanisms by which nano and microscale particulates can alter skin immune responses in the context of skin allergy. Nano and microscale particles are ubiquitous in the environment. They are derived from numerous sources including air pollution, cigarette smoke and the degradation of plastic waste, which lead to unintentional skin contact. Due to their unique optical, physiochemical and mechanical properties, nanomaterials they are increasingly exploited in industrial applications and are formulated into consumer products including cosmetic lotions thus increasing the probability skin exposure. Our studies find that skin exposure to nanoparticles can exacerbate and in some cases mitigate skin allergic symptoms. What is interesting is that heathy interfollicular skin is a formidable barrier that hinders nanoparticle penetration. Conditions that disrupt the skin barrier function, such as ultraviolet radiation induced sunburn, can enhance penetration, the free diffusion of nanoparticles into the skin does not occur. Rather nanoparticles tend to collect in the stratum corneum layers, skin furrows and hair follicles. This means that the profound impact that nanoparticles exert on skin immune responses likely results from signaling cascades derived in outermost layers of the epidermis. Our on-going studies seek to discover these mechanisms and the specific molecular and cellular signals that shift immune responses from proinflammatory to immunosuppressive. Specific focuses areas seek to understand the direct and indirect effect that nanomaterials have on mast cells and dendritic cells, which are key player in skin allergic responses. The goal is to develop novel strategies to induce tolerance to antigenic compound that induce skin allergy and to understand how nanomaterials may effect polarization of immune cells and their trafficking into the skin.

Technologies for Dissecting Single Cell Heterogeneity & Tissue Chip Drug Discovery
Tissue samples are comprised of heterogeneous cell populations and analysis of a bulk sample yields an average response where important information about a small but potentially relevant cell subpopulations is diluted out. High-throughput single cell screening technologies can facilitate the discovery of these rare cells. The DeLouise lab invented microbubble array technology and Nidus MB Technologies was founded to commercialize their use in high throughput single cell and tissue screening applications. Microphysiological tissue chips have been developed for drug screening. MBs are nanoliter (0.5 to >100 nL) spherical cavities molded into arrays containing 500 to >4000 MBs/cm2. The unique architecture of the MB provides a microenvironmental niche that cells can rapidly condition which favors single cell survival, proliferation and concentration of cell secreted factors. Assays have been developed to screen B cells to discover antigen specific antibodies and drug resistant cancer cells. Current efforts seek to develop a salivary gland tissue chip for screening radio protective drugs and develop an antigen agnostic assays to functionally discover neutralizing antibodies. High content image base detection methods are routinely used in these assays which requires development of sophisticated machine learning approaches for MB detection and analysis of the contents in each valid MB in the array over time. Ongoing efforts seek to develop user friendly graphical interfaces, powerful data analytics and to automate the cell/tissue retrieval process from selected MBs.

Patents

Hybrid Target Analyte Responsive Polymer Sensor with Optical Amplification

Issue date: September 23, 2014

Patent #: 8,841,137

Country: United States

Inventors: Lisa Bonanno, Lisa A DeLouise

Microfluidic Device and Method of Manufacturing the Microfluidic Device

Issue date: May 24, 2016

Patent #: 9,346,197

Country: United States

Inventors: Lisa A DeLouise

Microfluidic Device and Method of Manufacturing the Microfluidic Device

Issue date: October 04, 2016

Patent #: 9,457,497

Country: United States

Inventors: Lisa A DeLouise

Method of Enriching Stem and/or Progenitor Cells

Issue date: June 17, 2014

Patent #: 8,753,880

Country: United States

Inventors: Siddarth Chandrasekaran, Lisa A DeLouise

Publications

Journal Articles

Immunomodulatory effects of nanoparticles on dendritic cells in a model of allergic contact dermatitis: importance of PD-L2 expression.

Wong Lau A, Perez Pineda J, DeLouise LA

Scientific reports.. 2023 September 2513 (1):15992. Epub 09/25/2023.

Identifying novel radioprotective drugs via salivary gland tissue chip screening.

DeLouise L, Piraino L, Chen CY, Mereness J, Dunman P, Benoit D, Ovitt C

Research square.. 2023 September 22 Epub 09/22/2023.

Identifying novel radioprotective drugs via salivary gland tissue chip screening.

Piraino L, Chen CY, Mereness J, Dunman PM, Ovitt C, Benoit D, DeLouise L

bioRxiv : the preprint server for biology.. 2023 July 13 Epub 07/13/2023.

Slow hydrogel matrix degradation enhances salivary gland mimetic phenotype.

Mereness JA, Piraino L, Chen CY, Moyston T, Song Y, Shubin A, DeLouise LA, Ovitt CE, Benoit DSW

Acta biomaterialia.. 2023 May 5 Epub 05/05/2023.

Optimizing Soluble Cues for Salivary Gland Tissue Mimetics Using a Design of Experiments (DoE) Approach.

Piraino LR, Benoit DSW, DeLouise LA

Cells.. 2022 June 1811 (12)Epub 06/18/2022.

Author Correction: Development of a functional salivary gland tissue chip with potential for high-content drug screening.

Song Y, Uchida H, Sharipol A, Piraino L, Mereness JA, Ingalls MH, Rebhahn J, Newlands SD, DeLouise LA, Ovitt CE, Benoit DSW

Communications biology.. 2022 March 305 (1):315. Epub 03/30/2022.

Encapsulation of Primary Salivary Gland Acinar Cell Clusters and Intercalated Ducts (AIDUCs) within Matrix Metalloproteinase (MMP)-Degradable Hydrogels to Maintain Tissue Structure and Function.

Song Y, Sharipol A, Uchida H, Ingalls MH, Piraino L, Mereness JA, Moyston T, DeLouise LA, Ovitt CE, Benoit DSW

Advanced healthcare materials.. 2022 January 6 :e2101948. Epub 01/06/2022.

Salivary Gland Tissue Engineering Approaches: State of the Art and Future Directions.

Piraino LR, Benoit DSW, DeLouise LA

Cells.. 2021 July 810 (7)Epub 07/08/2021.

Author Correction: Development of a functional salivary gland tissue chip with potential for high-content drug screening.

Song Y, Uchida H, Sharipol A, Piraino L, Mereness JA, Ingalls MH, Rebhahn J, Newlands SD, DeLouise LA, Ovitt CE, Benoit DSW

Communications biology.. 2021 April 304 (1):533. Epub 04/30/2021.

Development of a functional salivary gland tissue chip with potential for high-content drug screening.

Song Y, Uchida H, Sharipol A, Piraino L, Mereness JA, Ingalls MH, Rebhahn J, Newlands SD, DeLouise LA, Ovitt CE, Benoit DSW

Communications biology.. 2021 March 194 (1):361. Epub 03/19/2021.

Silicon Nanomembrane Filtration and Imaging for the Evaluation of Microplastic Entrainment along a Municipal Water Delivery Route.

Madejski GR, Ahmad SD, Musgrave J, Flax J, Madejski JG, Rowley DA, DeLouise LA, Berger AJ, Knox WH, McGrath JL

Sustainability.. 2020 December 212 (24)Epub 12/20/2020.

The UVR Filter Octinoxate Modulates Aryl Hydrocarbon Receptor Signaling in Keratinocytes via Inhibition of CYP1A1 and CYP1B1.

Phelan-Dickinson SJ, Palmer BC, Chen Y, DeLouise LA

Toxicological sciences : an official journal of the Society of Toxicology.. 2020 June 30 Epub 06/30/2020.

Further studies in translatable model systems are needed to predict the impacts of human microplastic exposure.

Morgan SE, DeLouise LA

Open access journal of toxicology.. 2020 June 4 (3):79-82. Epub 06/05/2020.

Morphology-dependent titanium dioxide nanoparticle-induced keratinocyte toxicity and exacerbation of allergic contact dermatitis.

Palmer BC, DeLouise LA

HSOA journal of toxicology : current research.. 2020 4 (1)Epub 06/17/2020.

Amorphous silicon dioxide nanoparticles modulate immune responses in a model of allergic contact dermatitis.

Palmer BC, Jatana S, Phelan-Dickinson SJ, DeLouise LA

Scientific reports.. 2019 March 259 (1):5085. Epub 03/25/2019.

Multi-walled carbon nanotube oxidation dependent keratinocyte cytotoxicity and skin inflammation.

Palmer BC, Phelan-Dickenson SJ, DeLouise LA

Particle and fibre toxicology.. 2019 January 816 (1):3. Epub 01/08/2019.

Identifying drug resistant cancer cells using microbubble well arrays.

Pu Q, Spooner R, DeLouise LA

Biomedical microdevices.. 2017 September 19 (3):17. Epub 1900 01 01.

Immunomodulatory Effects of Nanoparticles on Skin Allergy.

Jatana S, Palmer BC, Phelan SJ, DeLouise LA

Scientific reports.. 2017 June 217 (1):3979. Epub 06/21/2017.

In vivo quantification of quantum dot systemic transport in C57BL/6 hairless mice following skin application post-ultraviolet radiation.

Jatana S, Palmer BC, Phelan SJ, Gelein R, DeLouise LA

Particle and fibre toxicology.. 2017 April 1414 (1):12. Epub 04/14/2017.

Effect of Nanoparticle Surface Coating on Cell Toxicity and Mitochondria Uptake.

Zheng H, Mortensen LJ, Ravichandran S, Bentley K, DeLouise LA

Journal of biomedical nanotechnology.. 2017 February 13 (2):155-66. Epub 1900 01 01.

From Dose to Response: In Vivo Nanoparticle Processing and Potential Toxicity.

Graham UM, Jacobs G, Yokel RA, Davis BH, Dozier AK, Birch ME, Tseng MT, Oberdörster G, Elder A, DeLouise L

Advances in experimental medicine and biology.. 2017 947 :71-100. Epub 1900 01 01.

Nanoparticle-Enabled Transdermal Drug Delivery Systems for Enhanced Dose Control and Tissue Targeting.

Palmer BC, DeLouise LA

Molecules : a journal of synthetic chemistry and natural product chemistry.. 2016 December 1521 (12)Epub 12/15/2016.

In vitro assays for determining the metastatic potential of melanoma cell lines with characterized in vivo invasiveness.

Chandrasekaran S, Giang UB, Xu L, DeLouise LA

Biomedical microdevices.. 2016 October 18 (5):89. Epub 1900 01 01.

Impact of Cosmetic Lotions on Nanoparticle Penetration through C57BL/6 Hairless Mouse and Human Skin: A Comparison Study.

Jatana S, Callahan LM, Pentland AP, DeLouise LA

Cosmetics.. 2016 March 3 (1)Epub 02/19/2016.

Development and characterization of antibody reagents for detecting nanoparticles.

Ravichandran S, Sullivan MA, Callahan LM, Bentley KL, DeLouise LA

Nanoscale.. 2015 December 217 (47):20042-54. Epub 11/16/2015.

UVB Dependence of Quantum Dot Reactive Oxygen Species Generation in Common Skin Cell Models.

Mortensen LJ, Faulknor R, Ravichandran S, Zheng H, DeLouise LA

Journal of biomedical nanotechnology.. 2015 September 11 (9):1644-52. Epub 1900 01 01.

Microbubble array diffusion assay for the detection of cell secreted factors.

Bobo B, Phelan D, Rebhahn J, Piepenbrink MS, Zheng B, Mosmann TR, Kobie JJ, DeLouise LA

Lab on a chip.. 2014 September 2114 (18):3640-50. Epub 07/31/2014.

Quantitative analysis of spherical microbubble cavity array formation in thermally cured polydimethylsiloxane for use in cell sorting applications.

Giang UB, Jones MC, Kaule MJ, Virgile CR, Pu Q, Delouise LA

Biomedical microdevices.. 2014 February 16 (1):55-67. Epub 1900 01 01.

Understanding engineered nanomaterial skin interactions and the modulatory effects of ultraviolet radiation skin exposure.

Jatana S, DeLouise LA

Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.. 2014 6 (1):61-79. Epub 10/03/2013.

Quantification of quantum dot murine skin penetration with UVR barrier impairment.

Mortensen LJ, Jatana S, Gelein R, Debenedetto A, de Mesy Bentley KL, Beck L, Elder A, Delouise L

Nanotoxicology.. 2013 December 7 (8):1386-98. Epub 04/17/2013.

The impact of UVB exposure and differentiation state of primary keratinocytes on their interaction with quantum dots.

Mortensen LJ, Ravichandran S, Delouise LA

Nanotoxicology.. 2013 November 7 (7):1244-54. Epub 10/25/2012.

Characterization of cell seeding and specific capture of B cells in microbubble well arrays.

Jones MC, Kobie JJ, Delouise LA

Biomedical microdevices.. 2013 June 15 (3):453-63. Epub 1900 01 01.

Thiol antioxidant-functionalized CdSe/ZnS quantum dots: synthesis, characterization, cytotoxicity.

Zheng H, Mortensen LJ, DeLouise LA

Journal of biomedical nanotechnology.. 2013 March 9 (3):382-92. Epub 1900 01 01.

Effect of homotypic and heterotypic interaction in 3D on the E-selectin mediated adhesive properties of breast cancer cell lines.

Chandrasekaran S, Geng Y, DeLouise LA, King MR

Biomaterials.. 2012 December 33 (35):9037-48. Epub 09/17/2012.

Applications of nanotechnology in dermatology.

DeLouise LA

The Journal of investigative dermatology.. 2012 March 132 (3 Pt 2):964-75. Epub 01/05/2012.

Quantification of human skin barrier function and susceptibility to quantum dot skin penetration.

Ravichandran S, Mortensen LJ, DeLuise LA

Nanotoxicology.. 2011 December 5 (4):675-86. Epub 12/10/2010.

Enriching and characterizing cancer stem cell sub-populations in the WM115 melanoma cell line.

Chandrasekaran S, DeLouise LA

Biomaterials.. 2011 December 32 (35):9316-27. Epub 09/13/2011.

Microenvironment induced spheroid to sheeting transition of immortalized human keratinocytes (HaCaT) cultured in microbubbles formed in polydimethylsiloxane.

Chandrasekaran S, Giang UB, King MR, DeLouise LA

Biomaterials.. 2011 October 32 (29):7159-68. Epub 07/02/2011.

The cytotoxicity of OPA-modified CdSe/ZnS core/shell quantum dots and its modulation by silibinin in human skin cells.

Zheng H, Chen G, Song F, DeLouise LA, Lou Z

Journal of biomedical nanotechnology.. 2011 October 7 (5):648-58. Epub 1900 01 01.

Near-IR fluorescence and reflectance confocal microscopy for imaging of quantum dots in mammalian skin.

Mortensen LJ, Glazowski CE, Zavislan JM, Delouise LA

Biomedical optics express.. 2011 June 12 (6):1610-25. Epub 05/19/2011.

Continuously perfused microbubble array for 3D tumor spheroid model.

Agastin S, Giang UB, Geng Y, Delouise LA, King MR

Biomicrofluidics.. 2011 June 5 (2):24110. Epub 06/03/2011.

Progress and challenges in quantifying skin permeability to nanoparticles using a quantum dot model.

Mortensen LJ, Ravichandran S, Zheng H, DeLouise LA

Journal of biomedical nanotechnology.. 2010 October 6 (5):596-604. Epub 1900 01 01.

Detection of the cancer marker CD146 expression in melanoma cells with semiconductor quantum dot label.

Zheng H, Chen G, DeLouise LA, Lou Z

Journal of biomedical nanotechnology.. 2010 August 6 (4):303-11. Epub 1900 01 01.

Integration of a Chemical-Responsive Hydrogel into a Porous Silicon Photonic Sensor for Visual Colorimetric Readout.

Bonanno LM, Delouise LA

Advanced functional materials.. 2010 January 1920 (4):573-578. Epub 1900 01 01.

Tunable detection sensitivity of opiates in urine via a label-free porous silicon competitive inhibition immunosensor.

Bonanno LM, Delouise LA

Analytical chemistry.. 2010 January 1582 (2):714-22. Epub 1900 01 01.

Tunable Detection Sensitivity of Opiates and Their Metabolites in Urine via a Label-Free Porous Silicon Competitive Inhibition Immunosensor

L. Bonanno, L. DeLouise.

Anal Chem. 2010; 82: 714-22L.

Integration of a chemical responsive hydrogel into a porous silicon photonic sensor for visual colorimetric readout.

L. Bonanno, L. DeLouise.

Adv Funct Mater. 2010; 20: 1-6.

Physicochemical Factors that Affect Nanoparticle Passage Across Epithelial Barriers

A. Elder, S. Vidyasagar, L. DeLouise.

Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 2009; 1(4): 434-50.

Photoinduced fluorescence enhancement and energy transfer effects of quantum dots in porous silicon

L. DeLouise, H. Ouyang.

psychica status solidi (c). 2009; 6(7): 1729-35.

Reusable Attachment Chemistry for Protein Probes in Porous Silicon Sensors

L. Bonanno, L. DeLouise.

physica status solidi (a). 2009; 206(6): 1299-1305.

Physicochemical factors that affect metal and metal oxide nanoparticle passage across epithelial barriers.

Elder A, Vidyasagar S, DeLouise L

Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.. 2009 1 (4):434-50. Epub 1900 01 01.

In vivo skin penetration of quantum dot nanoparticles in the murine model: the effect of UVR.

Mortensen LJ, Oberdörster G, Pentland AP, Delouise LA

Nano letters.. 2008 September 8 (9):2779-87. Epub 08/08/2008.

Label-free optical detection of peptide synthesis on a porous silicon scaffold/sensor.

Furbert P, Lu C, Winograd N, DeLouise L

Langmuir : the ACS journal of surfaces and colloids.. 2008 March 1824 (6):2908-15. Epub 02/05/2008.

Microfabrication of Bubbular Cavities in PDMS for Cell Sorting and Microcell Culture Applications.

U.T. Giang, M.R. King, and L. A. DeLouise.

J of Bionic Eng. 2008; 5(4): 308-16.

Quantum Dot Skin Penetration in a Sunburn Murine Model", Nano Letters 2008; 8(9); 2779-2787.

Mortensen, L., Pentland, A.P., Oberdorster, G., DeLouise, L.A.

Nano Letters. 2008; 8(9): 2779-87.

Optical Monitoring of Peptide Synthesis on Porous Silicon Microcavity Scaffold.

P. Furbert, C. Lu, N. Winograd and L. A. DeLouise,.

Langmuir. 2008; 24(6): 2908-15.

Microfabrication of cavities in polydimethylsiloxane using DRIE silicon molds.

Giang UB, Lee D, King MR, DeLouise LA

Lab on a chip.. 2007 December 7 (12):1660-2. Epub 10/12/2007.

Whole blood optical biosensor.

Bonanno LM, DeLouise LA

Biosensors & bioelectronics.. 2007 October 3123 (3):444-8. Epub 07/20/2007.

Enhancement of the evanescent field using polymer waveguides fabricated by deep UV exposure on mesoporous silicon.

Rabus DG, DeLouise LA, Ichihashi Y

Optics letters.. 2007 October 132 (19):2843-5. Epub 1900 01 01.

Steric crowding effects on target detection in an affinity biosensor.

Bonanno LM, Delouise LA

Langmuir : the ACS journal of surfaces and colloids.. 2007 May 823 (10):5817-23. Epub 04/11/2007.

Label-free quantitative detection of protein using macroporous silicon photonic bandgap biosensors.

Ouyang H, Delouise LA, Miller BL, Fauchet PM

Analytical chemistry.. 2007 February 1579 (4):1502-6. Epub 01/23/2007.

Microfabrication of Concave Cavities in Polydimethylsiloxane Using DRIE Silicon Molds.

U. Giang, D. Lee, M. King and L. DeLouise,.

Lab Chip. 2007; 7: 1660-62.

Enhancement of the evanescent field using polymer waveguides on mesoporous silicon fabricated by deep UV exposure.

D.G. Rabus, L.A. DeLouise, Y. Ichihashi,.

The Virtual Journal for Biomedical Optics. 2007; 32(19): 2843-45.

Integrated Whole Blood Filter – Biosensor

L. Bonanno, L. DeLouise,.

Biosensors and Bioelectronics. 2007; 23(3): 444-48.

Steric Crowding Effects on Target Detection in an Affinity Biosensor

L. Bonanno, L. DeLouise,.

Langmuir. 2007; 23(10): 5817-23.

Label-free quantitative detection of protein using macroporous silicon photonic bandgap biosensors.

H. Ouyang, L. A. DeLouise, B.L. Miller, P.M. Fauchet.

Anal Chem. 2007; 79(4): 1502-6.

Cross-correlation of optical microcavity biosensor response with immobilized enzyme activity. Insights into biosensor sensitivity.

DeLouise LA, Kou PM, Miller BL

Analytical chemistry.. 2005 May 1577 (10):3222-30. Epub 1900 01 01.

Enzyme immobilization in porous silicon: quantitative analysis of the kinetic parameters for glutathione-S-transferases.

Delouise LA, Miller BL

Analytical chemistry.. 2005 April 177 (7):1950-6. Epub 1900 01 01.

Hydrogel Supported Optical Microcavity Sensors

L.A. DeLouise, P.M. Fauchet, B.L. Miller, and A. P. Pentland.

Advanced Materials. 2005; 17(18): 2199-2203.

Quantatitive assessment of enzyme immobilization capacity in porous silicon.

DeLouise LA, Miller BL

Analytical chemistry.. 2004 December 176 (23):6915-20. Epub 1900 01 01.

Optimization of Mesoporous Silicon Microcavities for Proteomic Sensing

L.A. DeLouise and B.L. Miller.

Mat. Res. Soc. Symp. Proc. 2004; 782(A5): 1.

L.A. DeLouise and B.L. Miller.

Trends in Porous Silicon Biomedical Devices - Tuning Microstructure and Performance Trade-offs in Optical Biosensors

Biosensing with one-dimensional photonic bandgap structure

Ouyang, H.; DeLouise, L. A.; Christophersen, M.; Miller, B. L.; Fauchet, P. M.

Proc. SPIE. 2004; 5511: 71-80.

Quantitative Assessment of Enzyme Immobilization Capacity in Porous Silicon

L.A. DeLouise and B.L. Miller.

Analytical Chem. 2004; 76(23): 6915-20.

Investigation of the Chemical Mechanisms of Ta(110)/Ta(110)-suboxide Etch Selectivity Using Cl2 Molecular Beams

L.A. DeLouise.

Surface Science. 1995; 324: 233-248.

Surface Reactions on Semiconductors Studied by Molecular Beam Reactive Scattering

M. L. Yu and L.A. DeLouise.

Surface Science Reports. 1994; 19: 286.

Nitridation of GaAs(110) Using Energetic N+ and N2+ Ion Beams

L.A. DeLouise.

J. Vac. Sci. and Technol. 1993; A(11): 609.

Time Dependence of the Photodissociation of Sr+(NH3)2

C.A. Schmuttenmaer, J. Qian, S.G. Donnelly, M.J. DeLuca, D.F. Varley, L.A. DeLouise, R.J.D. Miller and J.M. Farrar.

J. Phys. Chem. 1993; 97(13): 3077.

Unusual Angular Dependence of Trapping Probability at Highly Corrugated Surfaces

Y.R. Wang, L.A. DeLouise and T.E. Orlowski.

J. Chem. Phys. 1993; 99: 5508.

Dynamical Study of the Ar+ Ion Enhanced Cl2/GaAs{110} Etch Rate Phenomenon : Dependence on the Reactant Flux Ratio

L.A. DeLouise.

International Symposium on Surface Science, Thin Films and Vacuum, Wuxi CHINA, Vacuum. 1992; 43: 1083.

Investigation of the Ar+ Ion Enhanced Cl2/GaAs{110} Etch Rate Phenomenon: Dependence on the Reactant Flux Ratio

L.A. DeLouise.

J. Appl. Phys. 1992; 72: 1608.

L.A. DeLouise.

Reactive N2+ Ion Bombardment of GaAs(100): A Method for GaN Thin Film Growth

Investigation of the Dynamics of the Cl2/GaAs(110) Thermal and the Ar+ Ion Enhanced Etching Mechanisms

L.A. DeLouise.

Proceedings International Workshop on Science and Technology for Surface Reaction Processes, Toyko JAPAN,. 1992; : 75.

Angle-Resolved Supersonic Molecular Beam Study of the Cl2/GaAs(110) Thermal Etching Reaction

L.A. DeLouise.

J. Chem. Phys. 1991; 94: 1528.

Evidence for Precursor-Mediated Cl2 Etching of GaAs(110): Effect of Surface Temperature and Incident Translational Energy on the Reaction Probability

L.A. DeLouise.

J. Vac. Sci. Technol. 1991; A9: 1732.

Supersonic Molecular Beam Study of the Trapping of Cl2 on GaAs(110): Dissociative Chemisorption and Desorption

L.A. DeLouise.

Surface Sci. Lett. 1991; 244: L87-L95.

Trapping Dynamics in Reactive Gas/Surface Scattering: Importance of Parallel Momentum Accommodation

L.A. DeLouise.

Chem. Phys. Lett.,. 1991; 180: 149.

Investigation of the Mechanism of Ar+ Ion-Assisted Cl2/GaAs(110) Etching: Role of Ion-Induced Charge Acceptor States

L.A. DeLouise.

J. Appl. Phys. 1991; 70: 1718.

Defect induced surface chemistry: A comparison of the adsorption and thermal decomposition of C2H4 on Rh{111} and Rh{331}

R. Levis, L.A. DeLouise, E.J. White, and N. Winograd.

Surface Science. 1990; 230: 35-46.

The Influence of Surface Atomic Steps on Site-Selective Adsorption Processes: Ethylidyne Formation on Rh(111) and Rh(331)

R. Levis, N. Winograd, and L.A. DeLouise.

JACS. 1987; 109: 6873.

Oxygen interaction with Pd3Sn: X-ray photoelectron Spectroscopy and Secondary Ion Mass Spectrometry

H.H. Rotermund, V. Penka, L.A. DeLouise, and C.R. Brundle.

J. Vac. Sci. Technol. 1987; A5: 1198.

SIMS/XPS Studies of Surface Reaction on Rh (111) and Rh (331)

E. White, L.A. DeLouise and N. Winograd.

Springer Series in Chemical Physics. 1986; 44: 219.

Molecular Beam Study of the Dissociation Chemisorption of Oxygen in W(110)

C. T. Rettner, L.A. DeLouise, and D.J. Auerbach.

J. Vac. Sci. Technol. 1986; 4: 1491.

Effect of Incidence Kinetic Energy and Surface Coverage on the Dissociative Chemisorption of Oxygen on W(110)

C. T. Rettner, L.A. DeLouise, and D. J. Auerbach.

J. Chem. Phys. 1986; 85: 1131.

Adsorption and Desorption of NO From the Rh (111) and Rh (331) Surfaces

L.A. DeLouise and N. Winograd.

Surface Science. 1985; 159: 199-213.

Reduction of Nitric Oxide on the Carbon Pretreated Rh(331) Single Crystal Surface: Evidence For Molecular CN-Formation

L.A. DeLouise and N. Winograd.

Surface Science. 1985; 154: 79.

Velocity Dependence of Azimuthal Anisotropys in Ion Scattering from Rh(111)

CC. Chang, L.A. DeLouise, N. Winograd, and B.J. Garrison.

Surface Science. 1985; 154: 22-34.

Rotationally Mediated Selective Adsorption, Physisorption and Dissociative Chemisorption of HD on W(110)

C. T. Rettner, L.A. DeLouise, J. P. Cowin, D. J. Auerbach.

Chem. Phys. Lett. 1985; 118: 355.

Rotationally Mediated Selective Adsorption of HD on W(110): Physisorption Without Chemisorption

C. T. Rettner, L.A. DeLouise, J. P. Cowin, D. J. Auerbach,.

Faraday Discuss. Chem. Soc. 1985; 80: 1.

Characterization of CO Binding Sites on the Rh (111) and Rh (331) Surfaces by XPS and LEED: Comparison to EELS Results.

L.A. DeLouise, E. J. White and N. Winograd,.

Surface Science. 1984; 147: 252-262.

Characterization of the Molecular Adsorption and Desorption of Carbon Monoxide from Rhodium Surfaces.

L.A. DeLouise and N. Winograd.

Surface Science. 1984; 138: 417.

Influence of Steps on the Reactivity of NO on Clean and Pretreated Rhodium Single Crystal Surfaces

L.A. DeLouise and N. Winograd.

Bull. Am. Phys. Soc. 1984; : 347.

Books

Safety of Nanoparticles: From Manufacturing to Medical Applications (2009)

Chapter: "Breeching Epithelial Barriers - Physiochemical Factors Impacting Nanoparticle Translocation and Toxicity",

Authors: DeLouise, L.A., Mortensen, L.; Elder, A.,

Publisher: Springer Science, Business Media 2009

Biophotonics (2008)

Chapter: Biodetection Using Silicon Photonic Crystal Microcavities,

Authors: PM Fauchet, BL Miller, LA DeLouise, MR Lee, and H Ouyang,

Publisher: Springer 2008

Surface Reactions on Semiconductors Studied by Molecular Beam Reactive (1994)

Authors: Ming L. Yu and L.A. DeLouise,

Publisher: Surface Science Reports 1994