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John M. Ashton, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 672
Rochester, NY 14642

Office: (585) 275-7276

Journal Articles

Showing all 11 journal articles available.

2015
Sivagnanalingam U, Balys M, Eberhardt A, Wang N, Myers JR, Ashton JM, Becker MW, Calvi LM, Mendler JH. "Residual Disease in a Novel Xenograft Model of RUNX1-Mutated, Cytogenetically Normal Acute Myeloid Leukemia." PloS one. 2015 10(7):e0132375. Epub 2015 Jul 15.
2013 Nov 22
Pei S, Minhajuddin M, Callahan KP, Balys M, Ashton JM, Neering SJ, Lagadinou ED, Corbett C, Ye H, Liesveld JL, O'Dwyer KM, Li Z, Shi L, Greninger P, Settleman J, Benes C, Hagen FK, Munger J, Crooks PA, Becker MW, Jordan CT. "Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells." The Journal of biological chemistry. 2013 Nov 22; 288(47):33542-58. Epub 2013 Oct 02.
2013 Jul 8
Miller PG, Al-Shahrour F, Hartwell KA, Chu LP, Järås M, Puram RV, Puissant A, Callahan KP, Ashton J, McConkey ME, Poveromo LP, Cowley GS, Kharas MG, Labelle M, Shterental S, Fujisaki J, Silberstein L, Alexe G, Al-Hajj MA, Shelton CA, Armstrong SA, Root DE, Scadden DT, Hynes RO, Mukherjee S, Stegmaier K, Jordan CT, Ebert BL. "In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling." Cancer cell. 2013 Jul 8; 24(1):45-58. Epub 2013 Jun 13.
2013 Mar 7
Lagadinou ED, Sach A, Callahan K, Rossi RM, Neering SJ, Minhajuddin M, Ashton JM, Pei S, Grose V, O'Dwyer KM, Liesveld JL, Brookes PS, Becker MW, Jordan CT. "BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells." Cell stem cell. 2013 Mar 7; 12(3):329-41. Epub 2013 Jan 17.
2012 Sep 7
Ashton JM, Balys M, Neering SJ, Hassane DC, Cowley G, Root DE, Miller PG, Ebert BL, McMurray HR, Land H, Jordan CT. "Gene sets identified with oncogene cooperativity analysis regulate in vivo growth and survival of leukemia stem cells." Cell stem cell. 2012 Sep 7; 11(3):359-72. Epub 2012 Aug 02.
2012 Apr
Zhao C, Xiu Y, Ashton J, Xing L, Morita Y, Jordan CT, Boyce BF. "Noncanonical NF-?B signaling regulates hematopoietic stem cell self-renewal and microenvironment interactions." Stem cells. 2012 Apr; 30(4):709-18.
2012 Jan 12
Frisch BJ, Ashton JM, Xing L, Becker MW, Jordan CT, Calvi LM. "Functional inhibition of osteoblastic cells in an in vivo mouse model of myeloid leukemia." Blood. 2012 Jan 12; 119(2):540-50. Epub 2011 Sep 28.
2010 Nov
Galloway CA, Ashton J, Sparks JD, Mooney RA, Smith HC. "Metabolic regulation of APOBEC-1 complementation factor trafficking in mouse models of obesity and its positive correlation with the expression of ApoB protein in hepatocytes." Biochimica et biophysica acta. 2010 Nov; 1802(11):976-85. Epub 2010 Jun 09.
2007 Oct 1
Neering SJ, Bushnell T, Sozer S, Ashton J, Rossi RM, Wang PY, Bell DR, Heinrich D, Bottaro A, Jordan CT. "Leukemia stem cells in a genetically defined murine model of blast-crisis CML." Blood. 2007 Oct 1; 110(7):2578-85. Epub 2007 Jun 29.
2006 Sep
Delvecchio VG, Connolly JP, Alefantis TG, Walz A, Quan MA, Patra G, Ashton JM, Whittington JT, Chafin RD, Liang X, Grewal P, Khan AS, Mujer CV. "Proteomic profiling and identification of immunodominant spore antigens of Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis." Applied and environmental microbiology. 2006 Sep; 72(9):6355-63.
2004
Alefantis T, Grewal P, Ashton J, Khan AS, Valdes JJ, Del Vecchio VG. "A rapid and sensitive magnetic bead-based immunoassay for the detection of staphylococcal enterotoxin B for high-through put screening." Molecular and cellular probes. 2004 18(6):379-82.