Shawn P. Murphy, Ph.D.

Shawn P. Murphy, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 668
Rochester, NY 14642

Journal Articles

Showing all 32 journal articles available.

2009
Choi, J.C.; Holtz, R.; Murphy, S.P. "Histone deacetylases inhibit IFN-y-inducible gene expression in mouse trophoblast cells". J Immunol. 2009; 182(10): 6307-6315.
2009
Apps, R.A.; Murphy, S.P.; Fernando, R.; Gardner, L.; Ahad, T.; Moffett, A. "Human Leukocyte Antigen (HLA) expression by normal trophoblast cells and placental cell lines using a novel method to characterize allotype specificities of anti-HLA antibodies". Immunology. 2009; 127(1): 26-39.
2009
Rimsza, L.M.; Chan, W.C.; Gascoyne, R.D.; Campo, E.; Jaffe, E.S.; Staudt, L.M.; Delabie, J.; Rosenwald, A.; Murphy S.P. "CIITA or RFX Coding Region Loss of Function Mutations Occur Rarely in Diffuse Large B Cell Lymphoma Cases and Cell Lines with Low Levels of Major Histocompatibility Complex Class II Expression." Haematologica. 2009; 94(4): 596-598.
2009
Murphy, S.P.; Tayade, C.; Ashkar, A.A.; Hattta, K.; Zhang, J.; Croy B.A. "Interferon-gamma in successful pregnancies". Biol Reprod. 2009; 80(5): 848-859.
2009
Cycon, K.; Clements, J; Holtz, R.; Fuji, H.; Murphy, S.P. "The immunogenicity of L1210 lymphoma clones correlates with the ability to function as antigen presenting cells". Immunology. 2009; 128: e641-651.
2009
Cycon, K.; Rimsza, L.; Murphy, S.P. "Alterations in CIITA constitute a common mechanism accounting for downregulation of MHC class II expression in diffuse large B cell lymphoma (DLBCL)". Experimental Hematology. 2009; 37(2): 184-194.
2007 Feb 1
Choi JC, Holtz R, Petroff MG, Alfaidy N, Murphy SP. "Dampening of IFN-gamma-inducible gene expression in human choriocarcinoma cells is due to phosphatase-mediated inhibition of the JAK/STAT-1 pathway." The Journal of immunology : official journal of the American Association of Immunologists. 2007 Feb 1; 178(3):1598-607.
2007
Choi, J.C.; Petroff, M.G.; Holtz, R.; Alfaidy, N.; Challis, J.R.; Murphy, S.P. "Dampening of IFN-y-inducible gene expression in human choriocarcinoma cells is due to phosphatase-mediated inhibition of the JAK/STAT-1 pathway". J Immunol. 2007; 178(3): 1589-1607.
2004 Jul 5
Murphy SP, Choi JC, Holtz R. "Regulation of major histocompatibility complex class II gene expression in trophoblast cells." Reproductive biology and endocrinology : RB&E. 2004 Jul 5; 2:52. Epub 2004 Jul 05.
2003 Nov
Chang CC, Murphy SP, Ferrone S. "Differential in vivo and in vitro HLA-G expression in melanoma cells: potential mechanisms." Human immunology. 2003 Nov; 64(11):1057-63.
2003 Sep
Holtz R, Choi JC, Petroff MG, Piskurich JF, Murphy SP. "Class II transactivator (CIITA) promoter methylation does not correlate with silencing of CIITA transcription in trophoblasts." Biology of reproduction. 2003 Sep; 69(3):915-24. Epub 2003 May 14.
2002 Sep 15
Murphy SP, Holtz R, Lewandowski N, Tomasi TB, Fuji H. "DNA alkylating agents alleviate silencing of class II transactivator gene expression in L1210 lymphoma cells." The Journal of immunology : official journal of the American Association of Immunologists. 2002 Sep 15; 169(6):3085-93.
1999
Li LH, Sen A, Murphy SP, Jahreis GP, Fuji H, Hui SW. "Apoptosis induced by DNA uptake limits transfection efficiency." Experimental cell research. 1999 253(2):541-50.
1998 Sep
Murphy SP, Tomasi TB. "Absence of MHC class II antigen expression in trophoblast cells results from a lack of class II transactivator (CIITA) gene expression." Molecular reproduction and development. 1998 Sep; 51(1):1-12.
1997 Aug
Murphy SP, Gollnick SO, Pazmany T, Maier P, Elkin G, Tomasi TB. "Repression of MHC class II gene transcription in trophoblast cells by novel single-stranded DNA binding proteins." Molecular reproduction and development. 1997 Aug; 47(4):390-403.
1995 Nov
Pazmany T, Murphy SP, Gollnick SO, Brooks SP, Tomasi TB. "Activation of multiple transcription factors and fos and jun gene family expression in cells exposed to a single electric pulse." Experimental cell research. 1995 Nov; 221(1):103-10.
1995 Jan 27
Bhattacharyya T, Karnezis AN, Murphy SP, Hoang T, Freeman BC, Phillips B, Morimoto RI. "Cloning and subcellular localization of human mitochondrial hsp70." The Journal of biological chemistry. 1995 Jan 27; 270(4):1705-10.
1994 Aug 30
Mathur SK, Sistonen L, Brown IR, Murphy SP, Sarge KD, Morimoto RI. "Deficient induction of human hsp70 heat shock gene transcription in Y79 retinoblastoma cells despite activation of heat shock factor 1." Proceedings of the National Academy of Sciences of the United States of America. 1994 Aug 30; 91(18):8695-9.
1994 Aug
Murphy SP, Gorzowski JJ, Sarge KD, Phillips B. "Characterization of constitutive HSF2 DNA-binding activity in mouse embryonal carcinoma cells." Molecular and cellular biology. 1994 Aug; 14(8):5309-17.
1994
Carr, V.M.; Murphy, S.P.; Morimoto, R.I.; Farbman, A. "Small subclass of olfactory neurons with specific bulbar projections reactive with monoclonal antibodies to the hsp70 heat shock protein." Carr, V.M., Murphy, S.P., Morimoto, R.I. and Farbman, A. 1994; 348: 150-160. Link
1993
Sarge, K.D.; Murphy, S.P.; Morimoto, R.I. "Activation of heat shock gene transcription of HSF1 involves oligomerization, nuclear translocation and acquisition of DNA binding and can occur in the absence of stress." Mol. Cell. Biol. 1993; 13(1392-1407). Link
1993
Kroeger, P.E.; Sarge, K.D.; Murphy, S.P.; Naki, A.; Morimoto, R.I. "Differential regulation of Heat shock gene transcription by a family of heat shock factors. (Review)." J. Occup. Environ. Health (Japan). 1993; 15: 55-63. Link
1992 Jul
Abravaya K, Myers MP, Murphy SP, Morimoto RI. "The human heat shock protein hsp70 interacts with HSF, the transcription factor that regulates heat shock gene expression." Genes & development. 1992 Jul; 6(7):1153-64.
1989
Espeseth, A.; Murphy, S.P.; Linney, E. "Retinoic acid receptor expression vector inhibits differentiation of F9 embryonal carcinoma cells". Espeseth, A., Murphy, S.P. and Linney, E. 1989; 3: 1647-1656. Link
1988 Aug
Murphy SP, Garbern J, Odenwald WF, Lazzarini RA, Linney E. "Differential expression of the homeobox gene Hox-1.3 in F9 embryonal carcinoma cells." Proceedings of the National Academy of Sciences of the United States of America. 1988 Aug; 85(15):5587-91.
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Murphy SP; Choi JC; Holtz, R. "Class II transactivator (CIITA) gene expression is silenced in mouse embryonic cells.".
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Choi JC; Holtz R; Murphy SP. "HDACs inhibit IFN-?-inducible gene expression in mouse trophoblast cells". .
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Cycon K; Clements J; Holtz R; Fuji H; Murphy SP. "The immunogenicity of L1210 lymphoma clones correlates with the ability to function as antigen presenting cells. Immunology." Immunology. .
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Cycon K; Rimzsa L; Murphy SP. "Alterations in CIITA constitute a common mechanism accounting for downregulation of MHC class II expression in diffuse large B cell lymphoma (DLBCL)." Experimental Hematology. .
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Murphy SP; Tayade C; Zhang J; Ashkar AA; Croy BA. "Interferon-gamma, immune cells and pregnancy". Biology of Reproduction. .
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Apps RA; Murphy SP; Fernando R; Gardner L; Ahad T; Moffett A. "Human Leukocyte Antigen (HLA) expression by normal trophoblast cells and placental cell lines using a novel method to characterize allotype specificities of anti-HLA antibodies." Immunology. .
0
Rimsza LM; Chan WC; Gascoyne RD; Campo E; Jaffe ES; Staudt LM; Delabie J; Rosenwald A; Murphy SP. "CIITA or RFX Coding Region Loss of Function Mutations Occur Rarely in Diffuse Large B Cell Lymphoma Cases and Cell Lines with Low Levels of Major Histocompatibility Complex Class II Expression." Haematologica. .