Coeli M. Lopes, Ph.D.

Coeli M. Lopes, Ph.D.

Contact Information

Aab Cardiovascular Research Institute
211 Bailey Road
West Henrietta, NY 14586

Appointment: (585) 275-URMC (8762)

Professional Bio

EDUCATION



BS: PUC-Rio, Brazil; Physics (1989)
MS: PUC-Rio, Brazil; Biophysics (1992)
PhD: Imperial College, UK; Biophysics (1997)
Postdoctoral Fellow - Yale University - Department of Physiology (1997-2000)
Postdoctoral Fellow - Mount Sinai School of Medicine - Department of Physiology and Biophysics (2000-2003)

APPOINTMENTS
2003-2004: Instructor - Mount Sinai School of Medicine - Department of Physiology and Biophysics
2004-2012: Assistant Professor - University of Rochester - Department of medicine - Cardiovascular Research Institute
2013-now: Associate Professor (Research) - University of Rochester - Department of medicine - Cardiovascular Research Institute

Patient Care Bio

Sudden arrhythmic death is the major cause of death in patients with congestive heart failure. In addition, heart failure increases the proarrhythmic effect of antiarrhythmic drugs, with the risk of drug induced Torsades de Pointes arrhythmias being approximately doubled by heart failure. Nonetheless the mechanisms of regulation of ion channels in heart failure are incompletely understood. Our works aims to undertand the pathological remodeling of cardiac ion currents in heart failure in order to develop novel treatements to reverse these effects and treat life treatening arrhythmias. We also study the effect of genetic mutations linked to the inherited cardiac arrhythmia Long QT syndrome.

We try to understand the role of specific genetic mutations on the patient clinical phenotype and response to treatment. Identification of disease- and mutation- specific therapies will ultimately allow tailoring of therapy to patients, optimizing treatment and lowering the overall risk of life threatening cardiac arrhythmias.

Awards & Honors (National)

NIH reviewer ESTA Study Section 2013
AHA reviewer - Cardiac Electrophysiology Study Section 2012 - Present
Scientist Development Grant | American Heart Association 2004 - Present

Awards & Honors (Local)

Postdoctoral Fellowship American Heart Association 2002 - 2004
New York City Board Fellow Award American Heart Association 2002
PhD Scholarship Federal Agency for Post-Graduate Education (CAPES- Brazil) 1992 - 1996
Graduate Student Scholarship National Research Council (CNPq Brazil) 1990 - 1992
Outstanding Basic Science Student Award PUC-Rio 1987
Full Merit University Scholarship PUC-Rio 1986 - 1989
Outstanding Basic Science Student Award PUC-Rio 1986

Current Appointments

Research Associate Professor - Department of Medicine, Aab Cardiovascular Research Institute (SMD) - Primary

Education

PhD | Biophysics | Imperial College1997
MS | Physics | Brazil-Pontificia Universidade Catolica1992
BS | Physics | Brazil-Pontificia Universidade Catolica1989