Coeli M. Lopes, Ph.D.

Coeli M. Lopes, Ph.D.

Contact Information

Aab Cardiovascular Research Institute
211 Bailey Road
West Henrietta, NY 14586

Office: (585) 276-9784
Fax: (585) 276-9829
Lab: (585) 276-9834
Administrative: (585) 276-9800

Journal Articles

Showing all 30 journal articles available.

2013 May
Mathias A, Moss AJ, Lopes CM, Barsheshet A, McNitt S, Zareba W, Robinson JL, Locati EH, Ackerman MJ, Benhorin J, Kaufman ES, Platonov PG, Qi M, Shimizu W, Towbin JA, Michael Vincent G, Wilde AA, Zhang L, Goldenberg I. "Prognostic implications of mutation-specific QTc standard deviation in congenital long QT syndrome." Heart rhythm : the official journal of the Heart Rhythm Society.. 2013 May; 10(5):720-5. Epub 2013 Jan 29.
2013 Mar
Mullally J, Goldenberg I, Moss AJ, Lopes CM, Ackerman MJ, Zareba W, McNitt S, Robinson JL, Benhorin J, Kaufman ES, Towbin JA, Barsheshet A. "Risk of life-threatening cardiac events among patients with long QT syndrome and multiple mutations." Heart rhythm : the official journal of the Heart Rhythm Society.. 2013 Mar; 10(3):378-82. Epub 2012 Nov 19.
2012 Nov 20
Hoefen R, Reumann M, Goldenberg I, Moss AJ, O-Uchi J, Gu Y, McNitt S, Zareba W, Jons C, Kanters JK, Platonov PG, Shimizu W, Wilde AA, Rice JJ, Lopes CM. "In silico cardiac risk assessment in patients with long QT syndrome: type 1: clinical predictability of cardiac models." Journal of the American College of Cardiology.. 2012 Nov 20; 60(21):2182-91.
2012 Jun
Costa J, Lopes CM, Barsheshet A, Moss AJ, Migdalovich D, Ouellet G, McNitt S, Polonsky S, Robinson JL, Zareba W, Ackerman MJ, Benhorin J, Kaufman ES, Platonov PG, Shimizu W, Towbin JA, Vincent GM, Wilde AA, Goldenberg I. "Combined assessment of sex- and mutation-specific information for risk stratification in type 1 long QT syndrome." Heart rhythm : the official journal of the Heart Rhythm Society.. 2012 Jun; 9(6):892-8. Epub 2012 Jan 28.
2012 Apr 24
Barsheshet A, Goldenberg I, O-Uchi J, Moss AJ, Jons C, Shimizu W, Wilde AA, McNitt S, Peterson DR, Zareba W, Robinson JL, Ackerman MJ, Cypress M, Gray DA, Hofman N, Kanters JK, Kaufman ES, Platonov PG, Qi M, Towbin JA, Vincent GM, Lopes CM. "Mutations in cytoplasmic loops of the KCNQ1 channel and the risk of life-threatening events: implications for mutation-specific response to ?-blocker therapy in type 1 long-QT syndrome." Circulation.. 2012 Apr 24; 125(16):1988-96. Epub 2012 Mar 28.
2012 Apr
Couderc JP, Xia X, Denjoy I, Extramiana F, Maison-Blanche P, Moss AJ, Zareba W, Lopes CM. "Genotype- and Sex-Specific QT-RR Relationship in the Type-1 Long-QT Syndrome." Journal of the American Heart Association. 2012 Apr; 1(2):e000570. Epub 2012 Apr 24.
2011 Oct
Migdalovich D, Moss AJ, Lopes CM, Costa J, Ouellet G, Barsheshet A, McNitt S, Polonsky S, Robinson JL, Zareba W, Ackerman MJ, Benhorin J, Kaufman ES, Platonov PG, Shimizu W, Towbin JA, Vincent GM, Wilde AA, Goldenberg I. "Mutation and gender-specific risk in type 2 long QT syndrome: implications for risk stratification for life-threatening cardiac events in patients with long QT syndrome." Heart rhythm : the official journal of the Heart Rhythm Society.. 2011 Oct; 8(10):1537-43. Epub 2011 Mar 25.
2011 Mar 30
Jons C, O-Uchi J, Moss AJ, Reumann M, Rice JJ, Goldenberg I, Zareba W, Wilde AA, Shimizu W, Kanters JK, McNitt S, Hofman N, Robinson JL, Lopes CM. "Use of mutant-specific ion channel characteristics for risk stratification of long QT syndrome patients." Science translational medicine. 2011 Mar 30; 3(76):76ra28.
2011 Jan 4
Goldenberg I, Horr S, Moss AJ, Lopes CM, Barsheshet A, McNitt S, Zareba W, Andrews ML, Robinson JL, Locati EH, Ackerman MJ, Benhorin J, Kaufman ES, Napolitano C, Platonov PG, Priori SG, Qi M, Schwartz PJ, Shimizu W, Towbin JA, Vincent GM, Wilde AA, Zhang L. "Risk for life-threatening cardiac events in patients with genotype-confirmed long-QT syndrome and normal-range corrected QT intervals." Journal of the American College of Cardiology.. 2011 Jan 4; 57(1):51-9.
2010 Oct
O-Uchi J, Lopes CM. "Combined blockade of ?- and ??-adrenoceptors in left ventricular remodeling induced by hypertension: beneficial or not?" Hypertension research : official journal of the Japanese Society of Hypertension. 2010 Oct; 33(10):984-5. Epub 2010 Aug 19.
2010 Aug 20
Casey LM, Pistner AR, Belmonte SL, Migdalovich D, Stolpnik O, Nwakanma FE, Vorobiof G, Dunaevsky O, Matavel A, Lopes CM, Smrcka AV, Blaxall BC. "Small molecule disruption of G beta gamma signaling inhibits the progression of heart failure." Circulation research.. 2010 Aug 20; 107(4):532-9. Epub 2010 Jun 24.
2010 Apr 16
Wojtovich AP, Williams DM, Karcz MK, Lopes CM, Gray DA, Nehrke KW, Brookes PS. "A novel mitochondrial K(ATP) channel assay." Circulation research.. 2010 Apr 16; 106(7):1190-6. Epub 2010 Feb 25.
2010
Matavel A, Medei E, Lopes CM. "PKA and PKC partially rescue long QT type 1 phenotype by restoring channel-PIP2 interactions." Channels.. 2010 4(1):3-11. Epub 2010 Jan 05.
2010
Couderc JP, Lopes CM. "Short and long QT syndromes: does QT length really matter?" Journal of electrocardiology. 2010 43(5):396-9.
2010
Kim JA, Lopes CM, Moss AJ, McNitt S, Barsheshet A, Robinson JL, Zareba W, Ackerman MJ, Kaufman ES, Towbin JA, Vincent M, Goldenberg I. "Trigger-specific risk factors and response to therapy in long QT syndrome type 2." Heart rhythm : the official journal of the Heart Rhythm Society.. 2010 7(12):1797-805. Epub 2010 Sep 17.
2010
Williams DM, Lopes CM, Rosenhouse-Dantsker A, Connelly HL, Matavel A, O-Uchi J, McBeath E, Gray DA. "Molecular basis of decreased Kir4.1 function in SeSAME/EAST syndrome." Journal of the American Society of Nephrology : JASN.. 2010 21(12):2117-29. Epub 2010 Nov 18.
2009 Aug
Jons C, Moss AJ, Lopes CM, McNitt S, Zareba W, Goldenberg I, Qi M, Wilde AA, Shimizu W, Kanters JK, Towbin JA, Ackerman MJ, Robinson JL. "Mutations in conserved amino acids in the KCNQ1 channel and risk of cardiac events in type-1 long-QT syndrome." Journal of cardiovascular electrophysiology.. 2009 Aug; 20(8):859-65. Epub 2009 Mar 13.
2009 May
Matavel A, Lopes CM. "PKC activation and PIP(2) depletion underlie biphasic regulation of IKs by Gq-coupled receptors." Journal of molecular and cellular cardiology.. 2009 May; 46(5):704-12. Epub 2009 Feb 20.
2007
Lopes C.M.B., Remon J.I., Matavel, A., Sui, J.L., Keselman, I., Medei E., Shen, Y., Rosenhouse-Dantsker A., Rohacs, T., Logothetis, D.E. "Protein Kinase A Modultates PLC-Dependent Regulation and PIP2-sensitivity of K+ Channels". Channels 1(2):124-34. 2007; .
2007
Lopes CM, Remon JI, Matavel A, Sui JL, Keselman I, Medei E, Shen Y, Rosenhouse-Dantsker A, Rohacs T, Logothetis DE. "Protein kinase A modulates PLC-dependent regulation and PIP2-sensitivity of K+ channels." Channels.. 2007 1(2):124-34. Epub 2007 Apr 23.
2005 May
Rohács T, Lopes CM, Michailidis I, Logothetis DE. "PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain." Nature neuroscience.. 2005 May; 8(5):626-34. Epub 2005 Apr 24.
2005 Apr 1
Lopes CM, Rohács T, Czirják G, Balla T, Enyedi P, Logothetis DE. "PIP2 hydrolysis underlies agonist-induced inhibition and regulates voltage gating of two-pore domain K+ channels." The Journal of physiology.. 2005 Apr 1; 564(Pt 1):117-29. Epub 2005 Jan 27.
2004 Sep 3
Du X, Zhang H, Lopes C, Mirshahi T, Rohacs T, Logothetis DE. "Characteristic interactions with phosphatidylinositol 4,5-bisphosphate determine regulation of kir channels by diverse modulators." The Journal of biological chemistry.. 2004 Sep 3; 279(36):37271-81. Epub 2004 May 20.
2003 Aug 1
Meyers MB, Fischer A, Sun YJ, Lopes CM, Rohacs T, Nakamura TY, Zhou YY, Lee PC, Altschuld RA, McCune SA, Coetzee WA, Fishman GI. "Sorcin regulates excitation-contraction coupling in the heart." The Journal of biological chemistry.. 2003 Aug 1; 278(31):28865-71. Epub 2003 May 16.
2003 Mar 27
Zhang H, Craciun LC, Mirshahi T, Rohács T, Lopes CM, Jin T, Logothetis DE. "PIP(2) activates KCNQ channels, and its hydrolysis underlies receptor-mediated inhibition of M currents." Neuron.. 2003 Mar 27; 37(6):963-75.
2003 Jan 21
Rohács T, Lopes CM, Jin T, Ramdya PP, Molnár Z, Logothetis DE. "Specificity of activation by phosphoinositides determines lipid regulation of Kir channels." Proceedings of the National Academy of Sciences of the United States of America.. 2003 Jan 21; 100(2):745-50. Epub 2003 Jan 13.
2002 Jun 13
Lopes CM, Zhang H, Rohacs T, Jin T, Yang J, Logothetis DE. "Alterations in conserved Kir channel-PIP2 interactions underlie channelopathies." Neuron.. 2002 Jun 13; 34(6):933-44.
2002
T. Rohacs, C. Lopes, T. Mirshahi, T. Jin, H. Zhang, D.E. Logothetis. "Assaying phosphatidylinositol bisphosphate regulation of potassium channels G protein pathways: effector mechanisms". Meth. Enz. 2002; 345: 71-92. Link
2001 Jul 6
Lopes CM, Zilberberg N, Goldstein SA. "Block of Kcnk3 by protons. Evidence that 2-P-domain potassium channel subunits function as homodimers." The Journal of biological chemistry.. 2001 Jul 6; 276(27):24449-52. Epub 2001 May 17.
2000
Lopes C.M.B., Gallagher P.G., Buck M.E., Butler M.H. and Goldstein S.A. "Proton block and voltage gating are potassium-dependent in the cardiac leak cahnnel kcnk3." J. Biol. Chem. 275, 16969-78.. 2000; 275: 16969-78. Link

Books

2000
C.M. Lopes, Goldstein S.A., Apkon M.. "Single cell electrophysiology and ion channelopathies". The molecular genetics of cardiac electrophysiology. CI Berul, J Tobin. : Kluwer Academic Publishers, 2000.