Research Bio
My research interests revolve around the use of computer modeling to understand the structure and thermodynamics of biological molecules. In particular, I am most interested in understanding the biology and physics of lipid-protein interactions. These interactions underlie a fantastic array of biological processes, including cell-signaling by GPCRs and some immune reactions, specifically the action of antimicrobial peptides.
2013 Apr
Grossfield A. "Special issue on lipid-protein interactions." Chemistry and physics of lipids. 2013 Apr 0; 169:1. |
2012 Jul 10
Leioatts N, Romo TD, Grossfield A. "Elastic Network Models are Robust to Variations in Formalism." Journal of chemical theory and computation. 2012 Jul 10; 8(7):2424-2434. Epub 2012 Jun 05. |
2012 Mar 7
Olausson BE, Grossfield A, Pitman MC, Brown MF, Feller SE, Vogel A. "Molecular dynamics simulations reveal specific interactions of post-translational palmitoyl modifications with rhodopsin in membranes." Journal of the American Chemical Society. 2012 Mar 7; 134(9):4324-31. Epub 2012 Feb 22. |
2012 Feb
Horn JN, Sengillo JD, Lin D, Romo TD, Grossfield A. "Characterization of a potent antimicrobial lipopeptide via coarse-grained molecular dynamics." Biochimica et biophysica acta. 2012 Feb 0; 1818(2):212-8. Epub 2011 Jul 28. |
2011 Aug
Romo TD, Bradney LA, Greathouse DV, Grossfield A. "Membrane binding of an acyl-lactoferricin B antimicrobial peptide from solid-state NMR experiments and molecular dynamics simulations." Biochimica et biophysica acta. 2011 Aug 0; 1808(8):2019-30. Epub 2011 Apr 06. |
