Joshua C. Munger, Ph.D.

Joshua C. Munger, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 712
Rochester, NY 14642

Office: (585) 273-4800
Fax: (585) 275-6007

Books

Journal Articles

Showing all 20 journal articles available.

2014 Apr 1
Proschel C, Stripay JL, Shih CH, Munger JC, Noble MD. "Delayed transplantation of precursor cell-derived astrocytes provides multiple benefits in a rat model of Parkinsons." EMBO molecular medicine.. 2014 Apr 1; 6(4):504-18. Epub 2014 Jan 29.
2014 Jan
Ortiz-Riaño E, Ngo N, Devito S, Eggink D, Munger J, Shaw ML, de la Torre JC, Martínez-Sobrido L. "Inhibition of arenavirus by A3, a pyrimidine biosynthesis inhibitor." Journal of virology.. 2014 Jan; 88(2):878-89. Epub 2013 Nov 06.
2014
Mathers C, Spencer CM, Munger J. "Distinct domains within the human cytomegalovirus U(L)26 protein are important for wildtype viral replication and virion stability." PloS one. 2014 9(2):e88101. Epub 2014 Feb 05.
2013 Nov 22
Pei S, Minhajuddin M, Callahan KP, Balys M, Ashton JM, Neering SJ, Lagadinou ED, Corbett C, Ye H, Liesveld JL, O'Dwyer KM, Li Z, Shi L, Greninger P, Settleman J, Benes C, Hagen FK, Munger J, Crooks PA, Becker MW, Jordan CT. "Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells." The Journal of biological chemistry.. 2013 Nov 22; 288(47):33542-58. Epub 2013 Oct 02.
2012 Aug 30
Sasaki M, Knobbe CB, Munger JC, Lind EF, Brenner D, Brüstle A, Harris IS, Holmes R, Wakeham A, Haight J, You-Ten A, Li WY, Schalm S, Su SM, Virtanen C, Reifenberger G, Ohashi PS, Barber DL, Figueroa ME, Melnick A, Zúñiga-Pflücker JC, Mak TW. "IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics." Nature. 2012 Aug 30; 488(7413):656-9.
2012 Jan
McArdle J, Moorman NJ, Munger J. "HCMV targets the metabolic stress response through activation of AMPK whose activity is important for viral replication." PLoS pathogens. 2012 Jan; 8(1):e1002502. Epub 2012 Jan 26.
2011 Jul 5
Hollenbaugh JA, Munger J, Kim B. "Metabolite profiles of human immunodeficiency virus infected CD4+ T cells and macrophages using LC-MS/MS analysis." Virology.. 2011 Jul 5; 415(2):153-9. Epub 2011 May 11.
2011 Jun
Spencer CM, Schafer XL, Moorman NJ, Munger J. "Human cytomegalovirus induces the activity and expression of acetyl-coenzyme A carboxylase, a fatty acid biosynthetic enzyme whose inhibition attenuates viral replication." Journal of virology.. 2011 Jun; 85(12):5814-24. Epub 2011 Apr 06.
2011 Jan
McArdle J, Schafer XL, Munger J. "Inhibition of calmodulin-dependent kinase kinase blocks human cytomegalovirus-induced glycolytic activation and severely attenuates production of viral progeny." Journal of virology.. 2011 Jan; 85(2):705-14. Epub 2010 Nov 17.
2011
Wang R, Dillon CP, Shi LZ, Milasta S, Carter R, Finkelstein D, McCormick LL, Fitzgerald P, Chi H, Munger J, Green DR. "The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation." Immunity. 2011 35(6):871-82.
2008 Oct
Munger J, Bennett BD, Parikh A, Feng XJ, McArdle J, Rabitz HA, Shenk T, Rabinowitz JD. "Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy." Nature biotechnology. 2008 Oct; 26(10):1179-86. Epub 2008 Sep 28.
2006 Apr
Munger J, Yu D, Shenk T. "UL26-deficient human cytomegalovirus produces virions with hypophosphorylated pp28 tegument protein that is unstable within newly infected cells." Journal of virology.. 2006 Apr; 80(7):3541-8.
2006
Munger J, Bajad SU, Coller HA, Shenk T, Rabinowitz JD. "Dynamics of the cellular metabolome during human cytomegalovirus infection." PLoS pathogens. 2006 2(12):e132.
2003 Jun
Benetti L, Munger J, Roizman B. "The herpes simplex virus 1 US3 protein kinase blocks caspase-dependent double cleavage and activation of the proapoptotic protein BAD." Journal of virology.. 2003 Jun; 77(11):6567-73.
2003 Jan 20
Munger J, Hagglund R, Roizman B. "Infected cell protein No. 22 is subject to proteolytic cleavage by caspases activated by a mutant that induces apoptosis." Virology.. 2003 Jan 20; 305(2):364-70.
2003
Munger, J.; Zhou, G.; Roizman, B.;. "Cell death on demand: Herpes simplex viruses and apoptosis". In C. D. O?Connor (ed.), Microbial Subversion of Host Cells, Cambridge University Press, Cambridge. 2003; : 229-245. Link
2002 Jan
Hagglund R, Munger J, Poon AP, Roizman B. "U(S)3 protein kinase of herpes simplex virus 1 blocks caspase 3 activation induced by the products of U(S)1.5 and U(L)13 genes and modulates expression of transduced U(S)1.5 open reading frame in a cell type-specific manner." Journal of virology.. 2002 Jan; 76(2):743-54.
2001 Aug 28
Munger J, Roizman B. "The US3 protein kinase of herpes simplex virus 1 mediates the posttranslational modification of BAD and prevents BAD-induced programmed cell death in the absence of other viral proteins." Proceedings of the National Academy of Sciences of the United States of America.. 2001 Aug 28; 98(18):10410-5. Epub 2001 Aug 21.
2001 Jun
Munger J, Chee AV, Roizman B. "The U(S)3 protein kinase blocks apoptosis induced by the d120 mutant of herpes simplex virus 1 at a premitochondrial stage." Journal of virology.. 2001 Jun; 75(12):5491-7.
2000 Feb
Galvan V, Brandimarti R, Munger J, Roizman B. "Bcl-2 blocks a caspase-dependent pathway of apoptosis activated by herpes simplex virus 1 infection in HEp-2 cells." Journal of virology.. 2000 Feb; 74(4):1931-8.