Christopher L. Seplaki, Ph.D.

Christopher L. Seplaki, Ph.D.

Contact Information

Public Health Sciences
265 Crittenden Blvd.
Rochester, NY 14642

Administrative: (585) 275-8784
Office: (585) 273-1549
Fax: (585) 461-4532

Research Bio

Dr. Seplaki's overarching goals are to understand how challenges in the social and physical environment interact with the biological processes of aging, and how to translate that understanding into effective interventions that reduce disability and mortality among older adults. His research, spanning both the individual and population level, encompasses physical and social characteristics of the home environment that support or challenge elders, life stressors, and socioeconomic status, and examines how these factors are related to changes in biological indicators of several physiological systems and self-reports of physical and mental health. Key themes in his work include an emphasis on measurement and estimation issues and a focus on subclinical disease processes related to geriatric frailty and allostatic load, including development of measures of health risk related to multi-system dysregulation. Taken together, Dr. Seplaki's research seeks to provide an integrated perspective on trajectories of health in late life and, ultimately, identify opportunities to reduce disability and mortality and improve the ability of older adults to continue to live independently.

Keywords: Aging, disability, environment, frailty, biomarkers, measurement, health disparities

Awards & Honors (Local)

Behavioral and Social Sciences Section | Gerontological Association of America 2014
Mason F. Lord Poster Competition Honoring Dr. James Fries | Johns Hopkins School of Medicine, Division of Geriatrics 2007
RAND Summer Institute Full Scholarship 2003
Conference Student Competition, Highly Commended | International Health Economics Association 1999
Conference Pre- and Post Doctoral Poster Award | Association for Health Services Research 1999
Distinguished Teaching Assistant | Department of Economics, University of Wisconsin-Madison 1996
Rutgers Scholar 1994
John C. Daniel Memorial Award, Economics 1994

Recent Journal Articles

Showing the 5 most recent journal articles. 24 available »

2014 Aug
Seplaki CL, Agree EM, Weiss CO, Szanton SL, Bandeen-Roche K, Fried LP. "Assistive devices in context: cross-sectional association between challenges in the home environment and use of assistive devices for mobility." The Gerontologist. 2014 Aug; 54(4):651-60. Epub 2013 Apr 24.
2013 Jul
Kobrosly RW, Seplaki CL, Cory-Slechta DA, Moynihan J, van Wijngaarden E. "Multisystem physiological dysfunction is associated with depressive symptoms in a population-based sample of older adults." International journal of geriatric psychiatry. 2013 Jul; 28(7):718-27. Epub 2012 Sep 07.
2013 Mar
Cohen AA, Milot E, Yong J, Seplaki CL, Fülöp T, Bandeen-Roche K, Fried LP. "A novel statistical approach shows evidence for multi-system physiological dysregulation during aging." Mechanisms of ageing and development. 2013 Mar; 134(3-4):110-7. Epub 2013 Jan 31.
2012 Sep 15
Xue QL, Bandeen-Roche K, Mielenz TJ, Seplaki CL, Szanton SL, Thorpe RJ, Kalyani RR, Chaves PH, Dam TT, Ornstein K, RoyChoudhury A, Varadhan R, Yao W, Fried LP. "Patterns of 12-year change in physical activity levels in community-dwelling older women: can modest levels of physical activity help older women live longer?" American journal of epidemiology. 2012 Sep 15; 176(6):534-43. Epub 2012 Aug 30.
2012 Jan
Kobrosly RW, Seplaki CL, Jones CM, van Wijngaarden E. "Physiologic dysfunction scores and cognitive function test performance in U.S. adults." Psychosomatic medicine. 2012 Jan; 74(1):81-8. Epub 2011 Dec 07.

Current Appointments

Associate Professor - Department of Public Health Sciences (SMD) - Primary


PhD | Population Health | Univ Wisconsin-Madison2002
MS | Economics | Univ Wisconsin-Madison1997
BA | Economics | Rutgers University1994